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ONTOLOGY REPORT - ANNOTATIONS


Term:phospholipid catabolic process
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Accession:GO:0009395 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
Synonyms:exact_synonym: phospholipid breakdown;   phospholipid catabolism;   phospholipid degradation



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phospholipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD12 abhydrolase domain containing 12, lysophospholipase involved_in ISO (PMID:30237167)
(MGI:5779796|PMID:25580854)
(MGI:6268556|PMID:30237167)
UniProt PMID:25580854 PMID:30237167 MGI:5779796 MGI:6268556 NCBI chr23:1,496,183...1,562,738
Ensembl chr23:1,496,551...1,562,688
JBrowse link
G ABHD6 abhydrolase domain containing 6, acylglycerol lipase involved_in ISO (MGI:5528738|PMID:24095738) UniProt PMID:24095738 MGI:5528738 NCBI chr20:32,301,120...32,331,030
Ensembl chr20:32,302,104...32,330,998
JBrowse link
G ANGPTL3 angiopoietin like 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:47,524,390...47,532,931
Ensembl chr 5:47,525,365...47,532,899
JBrowse link
G APOA2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:21,263,641...21,265,887
Ensembl chr38:21,262,789...21,265,887
JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 involved_in ISO (PMID:15280042), (PMID:26371182) UniProt PMID:15280042 PMID:26371182 NCBI chr13:18,586,886...18,697,339
Ensembl chr13:18,587,129...18,697,324
JBrowse link
G PLBD1 phospholipase B domain containing 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr27:32,031,073...32,081,910
Ensembl chr27:32,030,824...32,081,918
JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049
JBrowse link
G PLD1 phospholipase D1 ISO RGD PMID:16459925 RGD:2299904 NCBI chr34:35,917,759...36,080,383
Ensembl chr34:35,921,058...36,121,631
JBrowse link
G PLD2 phospholipase D2 ISO RGD PMID:16459925 RGD:2299904 NCBI chr 5:31,755,881...31,767,131
Ensembl chr 5:31,756,433...31,767,066
JBrowse link
G PLPP1 phospholipid phosphatase 1 involved_in ISO (PMID:1334090) UniProt PMID:1334090 NCBI chr 2:42,761,712...42,854,515
Ensembl chr 2:42,763,026...42,854,802
JBrowse link
G PNLIPRP2 pancreatic lipase related protein 2 involved_in ISO (PMID:18702514) UniProt PMID:18702514 NCBI chr28:27,190,641...27,212,185
Ensembl chr28:27,139,230...27,212,178
JBrowse link
glycerophospholipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD12 abhydrolase domain containing 12, lysophospholipase involved_in ISO (PMID:25290914) BHF-UCL PMID:25290914 NCBI chr23:1,496,183...1,562,738
Ensembl chr23:1,496,551...1,562,688
JBrowse link
G GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:18,103,273...18,108,818
Ensembl chr 6:18,103,267...18,108,533
JBrowse link
G LIPC lipase C, hepatic type ISO phosphatidylcholine, phosphatidylethanolamine hydrolysis RGD PMID:9048565 RGD:2308766 NCBI chr30:23,432,460...23,584,037
Ensembl chr30:23,432,493...23,584,037
JBrowse link
G PLA2G4A phospholipase A2 group IVA involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:19,804,412...19,955,215
Ensembl chr 7:19,832,664...19,966,936
JBrowse link
G PLA2G4B phospholipase A2, group IVB (cytosolic) involved_in ISO (PMID:10085124) UniProt PMID:10085124 NCBI chr30:8,865,941...8,878,687
Ensembl chr30:8,859,257...8,876,395
JBrowse link
G PLA2G4D phospholipase A2 group IVD involved_in ISO (PMID:14709560) UniProt PMID:14709560 NCBI chr30:9,091,147...9,115,090
Ensembl chr30:9,092,001...9,115,363
JBrowse link
G PRDX6 peroxiredoxin 6 involved_in ISO (PMID:10893423) CAFA PMID:10893423 NCBI chr 7:25,663,238...25,675,855
Ensembl chr 7:25,663,579...25,675,754
JBrowse link
G SMPD4 sphingomyelin phosphodiesterase 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:30,397,687...30,419,072
Ensembl chr26:30,398,768...30,418,979
JBrowse link
negative regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC1 apolipoprotein C1 involved_in ISO (PMID:2302419) BHF-UCL PMID:2302419 NCBI chr 1:110,520,177...110,522,563
Ensembl chr 1:110,520,198...110,631,412
JBrowse link
phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:18,586,886...18,697,339
Ensembl chr13:18,587,129...18,697,324
JBrowse link
G GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 involved_in ISO (MGI:5616003|PMID:25528375) UniProt PMID:25528375 MGI:5616003 NCBI chr 6:18,103,273...18,108,818
Ensembl chr 6:18,103,267...18,108,533
JBrowse link
G PLA2G10 phospholipase A2 group X involved_in ISO (PMID:12021277) UniProt PMID:12021277 NCBI chr 6:28,573,239...28,591,714
Ensembl chr 6:28,574,387...28,591,703
JBrowse link
G PLA2G15 phospholipase A2 group XV involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:81,269,914...81,280,700
Ensembl chr 5:81,269,920...81,280,700
JBrowse link
G PLA2G4A phospholipase A2 group IVA involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:19,804,412...19,955,215
Ensembl chr 7:19,832,664...19,966,936
JBrowse link
G PLA2G5 phospholipase A2 group V involved_in ISO (PMID:23533611) UniProt PMID:23533611 NCBI chr 2:78,762,851...78,781,642
Ensembl chr 2:78,762,852...78,781,983
JBrowse link
G PLA2G6 phospholipase A2 group VI involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:26,499,033...26,559,533
Ensembl chr10:26,509,695...26,634,087
JBrowse link
G PLA2G7 phospholipase A2 group VII involved_in ISS UniProt GO_REF:0000024 NCBI chr12:14,866,229...14,908,230
Ensembl chr12:14,866,229...14,908,114
JBrowse link
G PLB1 phospholipase B1 involved_in ISO PMID:9442065
PMID:9442064
UniProt PMID:9442064 PMID:9442065 RGD:30309923 RGD:633237 NCBI chr17:22,420,679...22,558,318
Ensembl chr17:22,440,651...22,557,737
JBrowse link
G PNLIPRP2 pancreatic lipase related protein 2 involved_in ISO (PMID:17401110) UniProt PMID:17401110 NCBI chr28:27,190,641...27,212,185
Ensembl chr28:27,139,230...27,212,178
JBrowse link
G PNPLA7 patatin like phospholipase domain containing 7 involved_in ISO (MGI:6393153|PMID:28887301) UniProt PMID:28887301 MGI:6393153 NCBI chr 9:48,221,754...48,286,352
Ensembl chr 9:48,221,514...48,286,352
JBrowse link
G PNPLA8 patatin like phospholipase domain containing 8 involved_in ISO (PMID:15695510) UniProt PMID:15695510 NCBI chr18:12,134,921...12,181,496
Ensembl chr18:12,141,830...12,179,974
JBrowse link
phosphatidylethanolamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G15 phospholipase A2 group XV involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:81,269,914...81,280,700
Ensembl chr 5:81,269,920...81,280,700
JBrowse link
G PLB1 phospholipase B1 involved_in ISO PMID:9442064 UniProt PMID:9442064 RGD:30309923 NCBI chr17:22,420,679...22,558,318
Ensembl chr17:22,440,651...22,557,737
JBrowse link
G PNPLA8 patatin like phospholipase domain containing 8 involved_in ISO (PMID:15695510) UniProt PMID:15695510 NCBI chr18:12,134,921...12,181,496
Ensembl chr18:12,141,830...12,179,974
JBrowse link
phosphatidylglycerol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G4A phospholipase A2 group IVA involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:19,804,412...19,955,215
Ensembl chr 7:19,832,664...19,966,936
JBrowse link
G PLB1 phospholipase B1 involved_in ISO PMID:9442064 UniProt PMID:9442064 RGD:30309923 NCBI chr17:22,420,679...22,558,318
Ensembl chr17:22,440,651...22,557,737
JBrowse link
phosphatidylinositol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INPP5F inositol polyphosphate-5-phosphatase F acts_upstream_of_or_within ISO (MGI:4943859|PMID:19875726) MGI PMID:19875726 MGI:4943859 NCBI chr28:29,878,489...29,945,598
Ensembl chr28:29,858,658...29,944,490
JBrowse link
G PLCB1 phospholipase C beta 1 ISO RGD PMID:8387502 RGD:11535163 NCBI chr24:13,337,285...13,996,218
Ensembl chr24:13,322,296...13,995,539
JBrowse link
G PLCB3 phospholipase C beta 3 ISO RGD PMID:8387502 RGD:11535163 NCBI chr18:52,793,848...52,809,065
Ensembl chr18:52,793,838...52,809,070
JBrowse link
phosphatidylserine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD12 abhydrolase domain containing 12, lysophospholipase acts_upstream_of_or_within
involved_in
ISO (MGI:5469248|PMID:23297193)
(PMID:30643283)
MGI
UniProt
PMID:23297193 PMID:30643283 MGI:5469248 NCBI chr23:1,496,183...1,562,738
Ensembl chr23:1,496,551...1,562,688
JBrowse link
G ABHD16A abhydrolase domain containing 16A, phospholipase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:1,167,723...1,182,520
Ensembl chr12:1,167,721...1,182,453
JBrowse link
platelet activating factor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G10 phospholipase A2 group X involved_in ISO (PMID:16962371) UniProt PMID:16962371 NCBI chr 6:28,573,239...28,591,714
Ensembl chr 6:28,574,387...28,591,703
JBrowse link
G PLA2G7 phospholipase A2 group VII involved_in ISS UniProt GO_REF:0000024 NCBI chr12:14,866,229...14,908,230
Ensembl chr12:14,866,229...14,908,114
JBrowse link
positive regulation of phospholipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC2 apolipoprotein C2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:110,504,806...110,506,986
Ensembl chr 1:110,504,815...110,506,961
JBrowse link
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (MGI:4947032|PMID:21177474) UniProt PMID:21177474 MGI:4947032 NCBI chr 9:1,887,093...1,894,728
Ensembl chr 9:1,887,201...1,897,473
JBrowse link
G PRKCD protein kinase C delta involved_in ISO (PMID:19279011) BHF-UCL PMID:19279011 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191
JBrowse link
regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LDLR low density lipoprotein receptor involved_in ISO (MGI:3784112|PMID:18175806) BHF-UCL PMID:18175806 MGI:3784112 NCBI chr20:50,115,175...50,152,443
Ensembl chr20:50,048,736...50,152,355
JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in ISO (MGI:3784112|PMID:18175806) BHF-UCL PMID:18175806 MGI:3784112 NCBI chr26:5,035,797...5,122,383
Ensembl chr26:5,049,407...5,121,468
JBrowse link
regulation of phospholipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5605608|PMID:25218477) Ensembl
MGI
PMID:25218477 GO_REF:0000107 MGI:5605608 NCBI chr37:16,512,027...16,531,269
Ensembl chr37:16,512,770...16,531,219
JBrowse link
sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:5529577|PMID:23973266)
GO_Central
MGI
PMID:21873635 PMID:23973266 MGI:5529577 NCBI chr21:29,714,418...29,719,035
Ensembl chr21:29,714,557...29,719,033
JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 acts_upstream_of_or_within ISO (MGI:5529577|PMID:23973266) MGI PMID:23973266 MGI:5529577 NCBI chr12:66,347,628...66,350,322
Ensembl chr12:66,323,022...66,350,322
JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5529577|PMID:23973266) Ensembl
MGI
PMID:23973266 GO_REF:0000107 MGI:5529577 NCBI chr 5:81,089,657...81,172,173
Ensembl chr 5:81,142,888...81,172,189
JBrowse link
G SMPD4 sphingomyelin phosphodiesterase 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:30,397,687...30,419,072
Ensembl chr26:30,398,768...30,418,979
JBrowse link
G SMPDL3A sphingomyelin phosphodiesterase acid like 3A NOT|involved_in ISO (PMID:26783088) UniProt PMID:26783088 NCBI chr 1:62,091,947...62,110,081
Ensembl chr 1:62,092,121...62,109,773
JBrowse link
G SMPDL3B sphingomyelin phosphodiesterase acid like 3B involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:72,427,085...72,450,547
Ensembl chr 2:72,418,872...72,450,737
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13874
    metabolic process 8976
      catabolic process 2006
        organic substance catabolic process 1666
          organophosphate catabolic process 121
            phospholipid catabolic process 42
              5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolic process 0
              ceramide phosphoethanolamine catabolic process 0
              copal-8-ol diphosphate(3-) catabolic process 0
              farnesyl diphosphate catabolic process 0
              geranylgeranyl diphosphate catabolic process 0
              glycerophospholipid catabolic process + 25
              positive regulation of phospholipid catabolic process + 3
              regulation of phospholipid catabolic process + 7
              sphinganine-1-phosphate catabolic process 0
              sphingomyelin catabolic process + 8
Path 2
Term Annotations click to browse term
  biological_process 13874
    metabolic process 8976
      cellular metabolic process 8165
        phosphorus metabolic process 2350
          phosphate-containing compound metabolic process 2336
            phospholipid metabolic process 311
              phospholipid catabolic process 42
                5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolic process 0
                ceramide phosphoethanolamine catabolic process 0
                copal-8-ol diphosphate(3-) catabolic process 0
                farnesyl diphosphate catabolic process 0
                geranylgeranyl diphosphate catabolic process 0
                glycerophospholipid catabolic process + 25
                positive regulation of phospholipid catabolic process + 3
                regulation of phospholipid catabolic process + 7
                sphinganine-1-phosphate catabolic process 0
                sphingomyelin catabolic process + 8
paths to the root