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ONTOLOGY REPORT - ANNOTATIONS


Term:2'-deoxyribonucleotide metabolic process
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Accession:GO:0009394 term browser browse the term
Definition:The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
Synonyms:exact_synonym: 2'-deoxyribonucleotide metabolism


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dADP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AK5 adenylate kinase 5 TAS (PMID:10215863) PINC PMID:10215863 NCBI chr 1:77,281,908...77,559,966
Ensembl chr 1:77,282,019...77,559,966
JBrowse link
dADP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT18 nudix hydrolase 18 IDA (PMID:22556419) UniProtKB PMID:22556419 NCBI chr 8:22,106,872...22,110,355
Ensembl chr 8:22,106,874...22,109,419
JBrowse link
dADP phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AK9 adenylate kinase 9 IDA (PMID:23416111) UniProtKB PMID:23416111 NCBI chr 6:109,492,855...109,691,202
Ensembl chr 6:109,492,856...109,691,217
JBrowse link
dAMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCK deoxycytidine kinase IEA GOC GO_REF:0000108 NCBI chr 4:70,993,649...71,030,914
Ensembl chr 4:70,992,538...71,030,914
JBrowse link
G DGUOK deoxyguanosine kinase IEA GOC GO_REF:0000108 NCBI chr 2:73,926,827...73,958,961
Ensembl chr 2:73,926,826...73,958,961
JBrowse link
dAMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase ISO (MGI:3640719|PMID:10720488) MGI PMID:10720488 MGI:3640719 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,619,522...44,652,233
JBrowse link
G UOX urate oxidase (pseudogene) ISO (MGI:3665448|PMID:16462750) MGI PMID:16462750 MGI:3665448 NCBI chr 1:84,364,958...84,384,801
Ensembl chr 1:84,363,706...84,397,831
JBrowse link
G URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase ISO (MGI:3665448|PMID:16462750) MGI PMID:16462750 MGI:3665448 NCBI chr13:27,977,717...27,988,693
Ensembl chr13:27,977,717...27,988,693
JBrowse link
G URAHP urate (hydroxyiso-) hydrolase, pseudogene ISO (MGI:3665448|PMID:16462750) MGI PMID:16462750 MGI:3665448 NCBI chr16:90,039,761...90,047,783
Ensembl chr16:90,039,761...90,047,773
JBrowse link
dATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADK adenosine kinase IEA Ensembl GO_REF:0000107 NCBI chr10:74,151,185...74,709,300
Ensembl chr10:74,151,202...74,709,963
JBrowse link
dATP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase IEA Ensembl GO_REF:0000107 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,619,522...44,652,233
JBrowse link
G NUDT1 nudix hydrolase 1 IDA (PMID:10373420) UniProtKB PMID:10373420 NCBI chr 7:2,242,226...2,251,145
Ensembl chr 7:2,242,222...2,251,146
JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 IDA (PMID:24141705) UniProtKB PMID:24141705 NCBI chr20:36,889,773...36,951,708
Ensembl chr20:36,889,773...36,951,901
Ensembl chr20:36,889,773...36,951,901
JBrowse link
dATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AK2 adenylate kinase 2 ISO RGD PMID:5010295 RGD:5490216 NCBI chr 1:33,007,940...33,036,883
Ensembl chr 1:33,007,940...33,080,996
JBrowse link
G AK3 adenylate kinase 3 ISO RGD PMID:5010295 RGD:5490216 NCBI chr 9:4,709,556...4,742,043
Ensembl chr 9:4,709,556...4,742,043
JBrowse link
G GUK1 guanylate kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:228,140,084...228,148,955
Ensembl chr 1:228,139,962...228,148,984
JBrowse link
G OGA O-GlcNAcase ISO RGD PMID:17573462 RGD:2305953 NCBI chr10:101,784,445...101,818,709
Ensembl chr10:101,784,443...101,818,465
JBrowse link
dCDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMPK1 cytidine/uridine monophosphate kinase 1 ISO RGD PMID:192455 RGD:5133256 NCBI chr 1:47,333,790...47,378,839
Ensembl chr 1:47,333,797...47,378,839
JBrowse link
dCTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCTPP1 dCTP pyrophosphatase 1 IMP
IBA
(PMID:24467396)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:24467396 NCBI chr16:30,423,615...30,430,030
Ensembl chr16:30,423,615...30,430,030
JBrowse link
depyrimidination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MBD4 methyl-CpG binding domain 4, DNA glycosylase TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr 3:129,430,947...129,440,029
Ensembl chr 3:129,430,944...129,440,179
JBrowse link
G NEIL1 nei like DNA glycosylase 1 TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr15:75,346,638...75,357,115
Ensembl chr15:75,346,955...75,357,115
JBrowse link
G NEIL2 nei like DNA glycosylase 2 TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr 8:11,769,710...11,787,345
Ensembl chr 8:11,769,639...11,787,345
JBrowse link
G NTHL1 nth like DNA glycosylase 1 TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr16:2,039,820...2,047,834
Ensembl chr16:2,039,815...2,047,866
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr 3:9,749,952...9,788,246
Ensembl chr 3:9,749,944...9,788,219
JBrowse link
G SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr12:54,121,274...54,188,985
Ensembl chr12:54,121,277...54,189,008
JBrowse link
G TDG thymine DNA glycosylase TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr12:103,965,842...103,988,874
Ensembl chr12:103,965,822...103,988,874
JBrowse link
G UNG uracil DNA glycosylase TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr12:109,097,597...109,110,992
Ensembl chr12:109,097,574...109,110,992
Ensembl chr12:109,097,574...109,110,992
JBrowse link
dGDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GUK1 guanylate kinase 1 IMP (PMID:31201273) UniProt PMID:31201273 NCBI chr 1:228,140,084...228,148,955
Ensembl chr 1:228,139,962...228,148,984
JBrowse link
dGDP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT18 nudix hydrolase 18 IDA (PMID:22556419) UniProtKB PMID:22556419 NCBI chr 8:22,106,872...22,110,355
Ensembl chr 8:22,106,874...22,109,419
JBrowse link
dGDP phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AK9 adenylate kinase 9 IDA
IBA
(PMID:23416111)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:23416111 NCBI chr 6:109,492,855...109,691,202
Ensembl chr 6:109,492,856...109,691,217
JBrowse link
dGMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NT5C 5', 3'-nucleotidase, cytosolic ISO (MGI:1353788|PMID:10681516) MGI PMID:10681516 MGI:1353788 NCBI chr17:75,130,228...75,131,965
Ensembl chr17:75,130,225...75,131,757
JBrowse link
G UOX urate oxidase (pseudogene) ISO (MGI:3665448|PMID:16462750) MGI PMID:16462750 MGI:3665448 NCBI chr 1:84,364,958...84,384,801
Ensembl chr 1:84,363,706...84,397,831
JBrowse link
G URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase ISO (MGI:3665448|PMID:16462750) MGI PMID:16462750 MGI:3665448 NCBI chr13:27,977,717...27,988,693
Ensembl chr13:27,977,717...27,988,693
JBrowse link
G URAHP urate (hydroxyiso-) hydrolase, pseudogene ISO (MGI:3665448|PMID:16462750) MGI PMID:16462750 MGI:3665448 NCBI chr16:90,039,761...90,047,783
Ensembl chr16:90,039,761...90,047,773
JBrowse link
G XDH xanthine dehydrogenase ISO (MGI:6306257|PMID:30936145) MGI PMID:30936145 MGI:6306257 NCBI chr 2:31,334,320...31,414,777
Ensembl chr 2:31,334,321...31,414,742
JBrowse link
dGMP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GUK1 guanylate kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:228,140,084...228,148,955
Ensembl chr 1:228,139,962...228,148,984
JBrowse link
dGTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT1 nudix hydrolase 1 IDA (PMID:10373420), (PMID:22556419) UniProtKB PMID:10373420, PMID:22556419 NCBI chr 7:2,242,226...2,251,145
Ensembl chr 7:2,242,222...2,251,146
JBrowse link
G NUDT15 nudix hydrolase 15 IDA
IBA
(PMID:22556419)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:22556419 NCBI chr13:48,037,726...48,052,755
Ensembl chr13:48,037,726...48,047,221
JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 IDA
IBA
(PMID:24217394)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:24217394 NCBI chr20:36,889,773...36,951,708
Ensembl chr20:36,889,773...36,951,901
Ensembl chr20:36,889,773...36,951,901
JBrowse link
dGTP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGUOK deoxyguanosine kinase IEA Ensembl GO_REF:0000107 NCBI chr 2:73,926,827...73,958,961
Ensembl chr 2:73,926,826...73,958,961
JBrowse link
dITP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT16 nudix hydrolase 16 ISS UniProtKB GO_REF:0000024 NCBI chr 3:131,381,671...131,388,830
Ensembl chr 3:131,381,671...131,388,830
JBrowse link
dTDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMPK2 cytidine/uridine monophosphate kinase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:6,840,417...6,866,635
Ensembl chr 2:6,840,570...6,866,635
JBrowse link
G DTYMK deoxythymidylate kinase IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 2:241,675,747...241,686,815
Ensembl chr 2:241,675,747...241,686,944
JBrowse link
dTMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCTD dCMP deaminase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:182,890,091...182,917,611
Ensembl chr 4:182,890,060...182,917,936
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 IEA Ensembl GO_REF:0000107 NCBI chr17:18,327,873...18,363,560
Ensembl chr17:18,327,860...18,363,563
JBrowse link
G TYMS thymidylate synthetase IDA
IBA
(PMID:11278511), (PMID:15093541), (PMID:8845352)
(PMID:21873635)
CAFA
GO_Central
PMID:8845352, PMID:11278511, PMID:15093541, PMID:21873635 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578
JBrowse link
dTTP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMPK2 cytidine/uridine monophosphate kinase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:6,840,417...6,866,635
Ensembl chr 2:6,840,570...6,866,635
JBrowse link
G DTYMK deoxythymidylate kinase IEA
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr 2:241,675,747...241,686,815
Ensembl chr 2:241,675,747...241,686,944
JBrowse link
G TBPL1 TATA-box binding protein like 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:133,952,174...133,990,432
Ensembl chr 6:133,952,170...133,990,432
JBrowse link
G TYMS thymidylate synthetase IEA UniProtKB GO_REF:0000041 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578
JBrowse link
dTTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCTPP1 dCTP pyrophosphatase 1 NOT IMP (PMID:24467396) UniProtKB PMID:24467396 NCBI chr16:30,423,615...30,430,030
Ensembl chr16:30,423,615...30,430,030
JBrowse link
dUDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMPK1 cytidine/uridine monophosphate kinase 1 ISO RGD PMID:3010881 RGD:5133253 NCBI chr 1:47,333,790...47,378,839
Ensembl chr 1:47,333,797...47,378,839
JBrowse link
G CMPK2 cytidine/uridine monophosphate kinase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:6,840,417...6,866,635
Ensembl chr 2:6,840,570...6,866,635
JBrowse link
G DTYMK deoxythymidylate kinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:241,675,747...241,686,815
Ensembl chr 2:241,675,747...241,686,944
JBrowse link
dUMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AL353753.1 putative deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:26,066,675...26,126,108
Ensembl chr 9:26,066,675...26,118,408
JBrowse link
G DCTD dCMP deaminase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:182,890,091...182,917,611
Ensembl chr 4:182,890,060...182,917,936
JBrowse link
G DUT deoxyuridine triphosphatase IEA
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr15:48,329,991...48,343,373
Ensembl chr15:48,331,011...48,343,373
JBrowse link
dUMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NT5M 5',3'-nucleotidase, mitochondrial IEA Ensembl GO_REF:0000107 NCBI chr17:17,303,373...17,347,663
Ensembl chr17:17,303,335...17,347,663
JBrowse link
dUTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AL353753.1 putative deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:26,066,675...26,126,108
Ensembl chr 9:26,066,675...26,118,408
JBrowse link
G DUT deoxyuridine triphosphatase IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000104 NCBI chr15:48,329,991...48,343,373
Ensembl chr15:48,331,011...48,343,373
JBrowse link
pyrimidine deoxyribonucleotide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NT5C 5', 3'-nucleotidase, cytosolic IDA
IBA
(PMID:10681516)
(PMID:21873635)
UniProtKB
GO_Central
PMID:10681516, PMID:21873635 NCBI chr17:75,130,228...75,131,965
Ensembl chr17:75,130,225...75,131,757
JBrowse link
G NT5M 5',3'-nucleotidase, mitochondrial IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:17,303,373...17,347,663
Ensembl chr17:17,303,335...17,347,663
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18672
    metabolic process 12302
      organic substance metabolic process 11734
        carbohydrate derivative metabolic process 1191
          deoxyribonucleotide metabolic process 44
            2'-deoxyribonucleotide metabolic process 39
              2'-deoxyribonucleotide biosynthetic process + 14
              purine deoxyribonucleotide metabolic process + 20
              pyrimidine deoxyribonucleotide metabolic process + 20
Path 2
Term Annotations click to browse term
  biological_process 18672
    metabolic process 12302
      cellular metabolic process 11278
        heterocycle metabolic process 6159
          nucleobase-containing compound metabolic process 5984
            nucleobase-containing small molecule metabolic process 672
              nucleoside phosphate metabolic process 582
                nucleotide metabolic process 574
                  deoxyribonucleotide metabolic process 44
                    2'-deoxyribonucleotide metabolic process 39
                      2'-deoxyribonucleotide biosynthetic process + 14
                      purine deoxyribonucleotide metabolic process + 20
                      pyrimidine deoxyribonucleotide metabolic process + 20
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.