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ONTOLOGY REPORT - ANNOTATIONS

Term:2'-deoxyribonucleotide metabolic process
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Accession:GO:0009394 term browser browse the term
Definition:The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
Synonyms:exact_synonym: 2'-deoxyribonucleotide metabolism


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2'-deoxyribonucleotide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC119876737 ribonucleoside-diphosphate reductase subunit M2-like involved_in IEA Ensembl GO_REF:0000107
G RRM1 ribonucleotide reductase catalytic subunit M1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:26,595,838...26,631,476
Ensembl chr21:26,595,914...26,631,135 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,106,515...7,113,868
Ensembl chr17:7,104,961...7,122,939 		JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:3,774,725...3,838,576
Ensembl chr13:3,799,025...3,837,934 		JBrowse link
dADP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT18 nudix hydrolase 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:35,139,580...35,144,066
Ensembl chr25:35,140,969...35,143,063 		JBrowse link
dAMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160 		JBrowse link
G NT5C1A 5'-nucleotidase, cytosolic IA involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:3,209,771...3,230,104
Ensembl chr15:3,209,869...3,222,983 		JBrowse link
G PNP purine nucleoside phosphorylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:17,808,454...17,815,987
Ensembl chr15:17,808,461...17,815,676 		JBrowse link
G UOX urate oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:63,482,384...63,513,538
Ensembl chr 6:63,436,236...63,513,478 		JBrowse link
G URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:11,682,304...11,693,143
Ensembl chr25:11,581,206...11,692,284 		JBrowse link
G XDH xanthine dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:24,900,708...24,960,748
Ensembl chr17:24,901,447...24,971,935 		JBrowse link
dAMP salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTG2 actin gamma 2, smooth muscle involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:49,144,184...49,168,872
Ensembl chr17:49,104,546...49,168,782 		JBrowse link
G ADK adenosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:24,540,626...25,047,032
Ensembl chr 4:24,540,659...25,046,464 		JBrowse link
G DCK deoxycytidine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:60,206,742...60,236,338
Ensembl chr13:60,205,937...60,235,678 		JBrowse link
G DGUOK deoxyguanosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:49,107,085...49,139,366
Ensembl chr17:49,104,546...49,168,782 		JBrowse link
dATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADK adenosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12163459) Ensembl
MGI		 PMID:12163459 GO_REF:0000107 NCBI chr 4:24,540,626...25,047,032
Ensembl chr 4:24,540,659...25,046,464 		JBrowse link
dATP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7731963)
(PMID:7592575)
(PMID:7670465)
(PMID:14607964), (PMID:9478961)		 Ensembl
MGI		 PMID:7592575 PMID:7670465 PMID:7731963 PMID:9478961 PMID:14607964 GO_REF:0000107 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160 		JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:25,623,997...25,676,336
Ensembl chr24:25,626,134...25,680,902 		JBrowse link
dATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AK2 adenylate kinase 2 ISO RGD PMID:5010295 RGD:5490216 NCBI chr 2:68,342,769...68,371,769
Ensembl chr 2:68,350,057...68,371,090 		JBrowse link
G GUK1 guanylate kinase 1 ISO RGD PMID:4307347 RGD:5147877 NCBI chr14:820,048...826,694
Ensembl chr14:820,093...827,250 		JBrowse link
G LOC480491 GTP:AMP phosphotransferase AK3, mitochondrial ISO RGD PMID:5010295 RGD:5490216 NCBI chr 9:10,282,452...10,283,479 JBrowse link
G OGA O-GlcNAcase ISO RGD PMID:17573462 RGD:2305953 NCBI chr28:14,376,824...14,405,409
Ensembl chr28:14,373,452...14,404,541 		JBrowse link
dCDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMPK1 cytidine/uridine monophosphate kinase 1 ISO RGD PMID:192455 RGD:5133256 NCBI chr15:13,324,235...13,357,387
Ensembl chr15:13,326,185...13,358,152 		JBrowse link
dCMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPYD dihydropyrimidine dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,789,786...52,564,802
Ensembl chr 6:51,814,573...52,580,923 		JBrowse link
G DPYS dihydropyrimidinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:5,583,795...5,659,355
Ensembl chr13:5,583,801...5,659,463 		JBrowse link
G NT5C 5', 3'-nucleotidase, cytosolic involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:5,342,793...5,344,432
Ensembl chr 9:5,343,378...5,344,380 		JBrowse link
G UPB1 beta-ureidopropionase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:28,194,968...28,225,977
Ensembl chr26:28,195,081...28,225,567 		JBrowse link
G UPP1 uridine phosphorylase 1 involved_in ISO (PMID:7744869) MGI PMID:7744869 NCBI chr18:108,215...120,213 JBrowse link
dCTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCTPP1 dCTP pyrophosphatase 1 involved_in IEA UniProt
TreeGrafter		 GO_REF:0000104 GO_REF:0000118 NCBI chr 6:17,679,681...17,683,644
Ensembl chr 6:17,679,722...17,683,570 		JBrowse link
dGDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GUK1 guanylate kinase 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:4307347 GO_REF:0000107 RGD:5147877 NCBI chr14:820,048...826,694
Ensembl chr14:820,093...827,250 		JBrowse link
dGDP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT18 nudix hydrolase 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:35,139,580...35,144,066
Ensembl chr25:35,140,969...35,143,063 		JBrowse link
dGMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 involved_in ISO PMID:17234634 MGI PMID:17234634 RGD:8553712 NCBI chr12:11,715,215...11,718,622
Ensembl chr12:11,715,271...11,718,717 		JBrowse link
G GDA guanine deaminase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:85,506,598...85,586,212
Ensembl chr 1:85,444,917...85,586,163 		JBrowse link
G NT5C 5', 3'-nucleotidase, cytosolic involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:5,342,793...5,344,432
Ensembl chr 9:5,343,378...5,344,380 		JBrowse link
G NT5C1A 5'-nucleotidase, cytosolic IA involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:3,209,771...3,230,104
Ensembl chr15:3,209,869...3,222,983 		JBrowse link
G NT5C2 5'-nucleotidase, cytosolic II involved_in ISO (PMID:5560407) MGI PMID:5560407 NCBI chr28:15,525,581...15,621,287
Ensembl chr28:15,526,790...15,621,235 		JBrowse link
G UOX urate oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:63,482,384...63,513,538
Ensembl chr 6:63,436,236...63,513,478 		JBrowse link
G URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:11,682,304...11,693,143
Ensembl chr25:11,581,206...11,692,284 		JBrowse link
G XDH xanthine dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:24,900,708...24,960,748
Ensembl chr17:24,901,447...24,971,935 		JBrowse link
dGMP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GUK1 guanylate kinase 1 ISO RGD PMID:4307347 RGD:5147877 NCBI chr14:820,048...826,694
Ensembl chr14:820,093...827,250 		JBrowse link
G NT5C2 5'-nucleotidase, cytosolic II involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:15,525,581...15,621,287
Ensembl chr28:15,526,790...15,621,235 		JBrowse link
dGTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT15 nudix hydrolase 15 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:3,416,702...3,424,607
Ensembl chr22:3,416,578...3,424,409 		JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr24:25,623,997...25,676,336
Ensembl chr24:25,626,134...25,680,902 		JBrowse link
dGTP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTG2 actin gamma 2, smooth muscle involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:49,144,184...49,168,872
Ensembl chr17:49,104,546...49,168,782 		JBrowse link
G DGUOK deoxyguanosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1664183), (PMID:7918681) Ensembl
MGI		 PMID:1664183 PMID:7918681 GO_REF:0000107 NCBI chr17:49,107,085...49,139,366
Ensembl chr17:49,104,546...49,168,782 		JBrowse link
dITP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT16 nudix hydrolase 16 acts_upstream_of_or_within ISO (PMID:20081199) MGI PMID:20081199 NCBI chr23:28,498,730...28,500,998
Ensembl chr23:28,498,652...28,499,998 		JBrowse link
dTDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMPK2 cytidine/uridine monophosphate kinase 2 involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:192455 GO_REF:0000118 RGD:5133256 NCBI chr17:4,466,615...4,478,546 JBrowse link
G DTYMK deoxythymidylate kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:8845311) RGD
MGI
TreeGrafter
InterPro		 PMID:220041 PMID:8845311 GO_REF:0000002 GO_REF:0000118 RGD:5133687 NCBI chr25:51,520,307...51,535,407
Ensembl chr25:51,520,581...51,526,069
Ensembl chr25:51,520,581...51,526,069 		JBrowse link
dTMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUT deoxyuridine triphosphatase involved_in ISO (PMID:10952785), (PMID:15322254) MGI PMID:10952785 PMID:15322254 NCBI chr30:14,572,766...14,585,621
Ensembl chr30:14,572,602...14,585,530 		JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in ISO (MGI:3849912|PMID:19513116) BHF-UCL PMID:19513116 MGI:3849912 NCBI chr 5:41,221,531...41,248,653
Ensembl chr 5:41,221,562...41,253,166 		JBrowse link
G TYMS thymidylate synthetase involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:9894005 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1545055 NCBI chr 7:67,487,927...67,497,747
Ensembl chr 7:67,487,927...67,497,747 		JBrowse link
dTMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NT5C 5', 3'-nucleotidase, cytosolic involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:5,342,793...5,344,432
Ensembl chr 9:5,343,378...5,344,380 		JBrowse link
G UPP1 uridine phosphorylase 1 NOT|involved_in ISO (MGI:3584214|PMID:15772079)
(PMID:12077348)		 UniProt
MGI		 PMID:12077348 PMID:15772079 MGI:3584214 NCBI chr18:108,215...120,213 JBrowse link
dTTP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMPK2 cytidine/uridine monophosphate kinase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:4,466,615...4,478,546 JBrowse link
G DTYMK deoxythymidylate kinase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:220041 GO_REF:0000118 RGD:5133687 NCBI chr25:51,520,307...51,535,407
Ensembl chr25:51,520,581...51,526,069
Ensembl chr25:51,520,581...51,526,069 		JBrowse link
G TBPL1 TATA-box binding protein like 1 acts_upstream_of_or_within ISO (PMID:11861477) MGI PMID:11861477 NCBI chr 1:26,898,344...26,938,452
Ensembl chr 1:26,899,859...26,936,995 		JBrowse link
G TYMS thymidylate synthetase involved_in IEA UniProt GO_REF:0000041 NCBI chr 7:67,487,927...67,497,747
Ensembl chr 7:67,487,927...67,497,747 		JBrowse link
dTTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCTPP1 dCTP pyrophosphatase 1 NOT|involved_in ISO (PMID:24467396) UniProt PMID:24467396 NCBI chr 6:17,679,681...17,683,644
Ensembl chr 6:17,679,722...17,683,570 		JBrowse link
dUDP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMPK1 cytidine/uridine monophosphate kinase 1 ISO RGD PMID:3010881 RGD:5133253 NCBI chr15:13,324,235...13,357,387
Ensembl chr15:13,326,185...13,358,152 		JBrowse link
G CMPK2 cytidine/uridine monophosphate kinase 2 involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:192455 GO_REF:0000118 RGD:5133256 NCBI chr17:4,466,615...4,478,546 JBrowse link
G DTYMK deoxythymidylate kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr25:51,520,307...51,535,407
Ensembl chr25:51,520,581...51,526,069
Ensembl chr25:51,520,581...51,526,069 		JBrowse link
dUMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUT deoxyuridine triphosphatase involved_in ISO
IEA		 RGD
TreeGrafter
UniProt
InterPro		 PMID:1315924 PMID:3032103 GO_REF:0000002 GO_REF:0000041 GO_REF:0000104 GO_REF:0000118 RGD:2300191 RGD:2301218 NCBI chr30:14,572,766...14,585,621
Ensembl chr30:14,572,602...14,585,530 		JBrowse link
dUMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPYD dihydropyrimidine dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,789,786...52,564,802
Ensembl chr 6:51,814,573...52,580,923 		JBrowse link
G DPYS dihydropyrimidinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:5,583,795...5,659,355
Ensembl chr13:5,583,801...5,659,463 		JBrowse link
G NT5C 5', 3'-nucleotidase, cytosolic involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:5,342,793...5,344,432
Ensembl chr 9:5,343,378...5,344,380 		JBrowse link
G NT5M 5',3'-nucleotidase, mitochondrial involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12234672) Ensembl
MGI		 PMID:12234672 GO_REF:0000107 NCBI chr 5:42,080,654...42,117,919
Ensembl chr 5:42,080,645...42,117,741 		JBrowse link
G UPB1 beta-ureidopropionase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:28,194,968...28,225,977
Ensembl chr26:28,195,081...28,225,567 		JBrowse link
G UPP1 uridine phosphorylase 1 involved_in ISO (PMID:14154460) MGI PMID:14154460 NCBI chr18:108,215...120,213 JBrowse link
dUTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUT deoxyuridine triphosphatase involved_in ISO
IEA		 RGD
InterPro
UniProt
TreeGrafter		 PMID:1315924 PMID:3032103 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 RGD:2300191 RGD:2301218 NCBI chr30:14,572,766...14,585,621
Ensembl chr30:14,572,602...14,585,530 		JBrowse link
pyrimidine deoxyribonucleotide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NT5C 5', 3'-nucleotidase, cytosolic involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:5,342,793...5,344,432
Ensembl chr 9:5,343,378...5,344,380 		JBrowse link
G NT5M 5',3'-nucleotidase, mitochondrial involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:42,080,654...42,117,919
Ensembl chr 5:42,080,645...42,117,741 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    metabolic process 10998
      organic substance metabolic process 10554
        carbohydrate derivative metabolic process 1131
          deoxyribose phosphate metabolic process 40
            2'-deoxyribonucleotide metabolic process 39
              2'-deoxyribonucleotide biosynthetic process + 16
              purine deoxyribonucleotide metabolic process + 22
              pyrimidine deoxyribonucleotide metabolic process + 14
Path 2
Term Annotations click to browse term
  biological_process 17917
    metabolic process 10998
      organic substance metabolic process 10554
        organic cyclic compound metabolic process 5907
          nucleobase-containing compound metabolic process 5439
            nucleobase-containing small molecule metabolic process 682
              nucleoside phosphate metabolic process 615
                nucleotide metabolic process 608
                  deoxyribonucleotide metabolic process 41
                    2'-deoxyribonucleotide metabolic process 39
                      2'-deoxyribonucleotide biosynthetic process + 16
                      purine deoxyribonucleotide metabolic process + 22
                      pyrimidine deoxyribonucleotide metabolic process + 14
paths to the root