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ONTOLOGY REPORT - ANNOTATIONS

Term:excinuclease repair complex
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Accession:GO:0009380 term browser browse the term
Definition:Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap.
Synonyms:exact_synonym: UvrABC excinuclease complex;   excinuclease ABC complex


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  cellular_component 28585
    protein-containing complex 6184
      catalytic complex 1789
        DNA repair complex 22
          excinuclease repair complex 0
Path 2
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  cellular_component 28585
    protein-containing complex 6184
      intracellular protein-containing complex 932
        endonuclease complex 41
          endodeoxyribonuclease complex 6
            excinuclease repair complex 0
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