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ONTOLOGY REPORT - ANNOTATIONS


Term:amine biosynthetic process
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Accession:GO:0009309 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
Synonyms:exact_synonym: amine anabolism;   amine biosynthesis;   amine formation;   amine synthesis


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amine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SULT1A2 sulfotransferase family 1A member 2 TAS (PMID:9119390) PINC PMID:9119390 NCBI chr16:28,591,943...28,597,070
Ensembl chr16:28,591,943...28,597,050
JBrowse link
histamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDC histidine decarboxylase TAS
IBA
IDA
IEA
(PMID:21873635)
(PMID:22767596)
Reactome
GO_Central
UniProtKB
PMID:21873635, PMID:22767596 GO_REF:0000041, Reactome:R-HSA-977301 NCBI chr15:50,241,945...50,266,049
Ensembl chr15:50,241,947...50,265,965
JBrowse link
G PRG3 proteoglycan 3, pro eosinophil major basic protein 2 IDA (PMID:10318872) UniProtKB PMID:10318872 NCBI chr11:57,376,769...57,381,150
Ensembl chr11:57,376,769...57,381,150
JBrowse link
indolalkylamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AANAT aralkylamine N-acetyltransferase TAS Reactome Reactome:R-HSA-209931 NCBI chr17:76,453,351...76,470,797
Ensembl chr17:76,453,351...76,470,117
JBrowse link
G ASMT acetylserotonin O-methyltransferase TAS Reactome Reactome:R-HSA-209931 NCBI chr  Y:1,595,455...1,643,081
NCBI chr  X:1,595,455...1,643,081
Ensembl chr  X:1,615,059...1,643,081
JBrowse link
G DDC dopa decarboxylase TAS Reactome Reactome:R-HSA-209931 NCBI chr 7:50,458,436...50,565,460
Ensembl chr 7:50,458,436...50,565,405
JBrowse link
G TPH1 tryptophan hydroxylase 1 TAS Reactome Reactome:R-HSA-209931 NCBI chr11:18,017,555...18,046,269
Ensembl chr11:18,017,564...18,042,426
JBrowse link
G TPH2 tryptophan hydroxylase 2 TAS Reactome Reactome:R-HSA-209931 NCBI chr12:71,938,845...72,032,440
Ensembl chr12:71,938,845...72,186,618
JBrowse link
octopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBH dopamine beta-hydroxylase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329
JBrowse link
G MOXD1 monooxygenase DBH like 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:132,296,055...132,401,520
Ensembl chr 6:132,296,055...132,401,475
JBrowse link
G MOXD2P monooxygenase DBH like 2, pseudogene IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:142,240,737...142,247,067
Ensembl chr 7:142,240,740...142,247,067
JBrowse link
polyamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC005258.1 novel protein, readthrough between OAZ1 and SPPL2B IEA UniProt GO_REF:0000043 Ensembl chr19:2,269,525...2,341,172 JBrowse link
G AZIN1 antizyme inhibitor 1 IEA InterPro GO_REF:0000002 NCBI chr 8:102,826,302...102,864,200
Ensembl chr 8:102,826,308...102,893,864
JBrowse link
G AZIN2 antizyme inhibitor 2 IEA InterPro GO_REF:0000002 NCBI chr 1:33,081,152...33,162,288
Ensembl chr 1:33,081,104...33,123,492
JBrowse link
G OAZ1 ornithine decarboxylase antizyme 1 IEA UniProt GO_REF:0000043 NCBI chr19:2,269,486...2,273,488
Ensembl chr19:2,269,509...2,273,490
JBrowse link
G OAZ2 ornithine decarboxylase antizyme 2 IEA UniProt GO_REF:0000043 NCBI chr15:64,687,574...64,703,281
Ensembl chr15:64,687,573...64,703,281
JBrowse link
G OAZ3 ornithine decarboxylase antizyme 3 IEA UniProt GO_REF:0000043 NCBI chr 1:151,762,969...151,771,330
Ensembl chr 1:151,762,899...151,771,334
JBrowse link
G ODC1 ornithine decarboxylase 1 IEA InterPro GO_REF:0000002 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
JBrowse link
G PAOX polyamine oxidase TAS Reactome Reactome:R-HSA-351200 NCBI chr10:133,379,262...133,391,694
Ensembl chr10:133,380,017...133,420,271
Ensembl chr10:133,380,017...133,420,271
JBrowse link
G SAT1 spermidine/spermine N1-acetyltransferase 1 TAS
IDA
(PMID:15283699) Reactome
UniProt
PMID:15283699 Reactome:R-HSA-351200 NCBI chr  X:23,783,158...23,786,223
Ensembl chr  X:23,783,173...23,786,226
JBrowse link
G SAT2 spermidine/spermine N1-acetyltransferase family member 2 NOT IDA (PMID:15283699) UniProt PMID:15283699 NCBI chr17:7,626,234...7,627,878
Ensembl chr17:7,626,234...7,627,876
JBrowse link
G SMOX spermine oxidase TAS Reactome Reactome:R-HSA-351200 NCBI chr20:4,148,828...4,187,732
Ensembl chr20:4,120,980...4,187,747
JBrowse link
G SRM spermidine synthase IEA
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000104 NCBI chr 1:11,054,589...11,060,053
Ensembl chr 1:11,054,584...11,060,020
JBrowse link
positive regulation of spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAOX polyamine oxidase IDA (PMID:16354669) UniProtKB PMID:16354669 NCBI chr10:133,379,262...133,391,694
Ensembl chr10:133,380,017...133,420,271
Ensembl chr10:133,380,017...133,420,271
JBrowse link
putrescine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ODC1 ornithine decarboxylase 1 ISO RGD PMID:1415709, PMID:10430362 RGD:1578320, RGD:7242912 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
JBrowse link
G PAOX polyamine oxidase IDA (PMID:16354669) UniProtKB PMID:16354669 NCBI chr10:133,379,262...133,391,694
Ensembl chr10:133,380,017...133,420,271
Ensembl chr10:133,380,017...133,420,271
JBrowse link
putrescine biosynthetic process from arginine, using agmatinase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGMAT agmatinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:15,571,699...15,585,051
Ensembl chr 1:15,571,699...15,585,051
JBrowse link
putrescine biosynthetic process from ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AZIN1 antizyme inhibitor 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:102,826,302...102,864,200
Ensembl chr 8:102,826,308...102,893,864
JBrowse link
G AZIN2 antizyme inhibitor 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:33,081,152...33,162,288
Ensembl chr 1:33,081,104...33,123,492
JBrowse link
G ODC1 ornithine decarboxylase 1 IEA
IBA
ISS
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024, GO_REF:0000041 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
JBrowse link
spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGMAT agmatinase IEA UniProt GO_REF:0000043 NCBI chr 1:15,571,699...15,585,051
Ensembl chr 1:15,571,699...15,585,051
JBrowse link
G AMD1 adenosylmethionine decarboxylase 1 IEA
IBA
(PMID:21873635) InterPro
UniProt
GO_Central
PMID:21873635 GO_REF:0000002, GO_REF:0000043 NCBI chr 6:110,814,617...110,895,713
Ensembl chr 6:110,874,770...110,898,879
JBrowse link
G SRM spermidine synthase IDA
IBA
IEA
(PMID:17585781)
(PMID:21873635)
UniProtKB
GO_Central
PMID:17585781, PMID:21873635 GO_REF:0000041 NCBI chr 1:11,054,589...11,060,053
Ensembl chr 1:11,054,584...11,060,020
JBrowse link
spermine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMD1 adenosylmethionine decarboxylase 1 IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 6:110,814,617...110,895,713
Ensembl chr 6:110,874,770...110,898,879
JBrowse link
G SMS spermine synthase IEA
IBA
(PMID:21873635) InterPro
GO_Central
UniProtKB
PMID:21873635 GO_REF:0000002, GO_REF:0000041 NCBI chr  X:21,940,709...21,994,837
Ensembl chr  X:21,940,709...21,994,837
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    metabolic process 12302
      nitrogen compound metabolic process 10513
        organonitrogen compound metabolic process 7191
          amine metabolic process 154
            amine biosynthetic process 26
              cellular biogenic amine biosynthetic process + 25
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.