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ONTOLOGY REPORT - ANNOTATIONS


Term:amine biosynthetic process
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Accession:GO:0009309 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
Synonyms:exact_synonym: amine anabolism;   amine biosynthesis;   amine formation;   amine synthesis



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catecholamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:17194738 RGD:5131263 NCBI chr14:43,366,849...43,414,398
Ensembl chr14:43,368,340...43,415,142
JBrowse link
G HDC histidine decarboxylase involved_in IEA UniProt GO_REF:0000043 NCBI chr30:16,201,222...16,223,452
Ensembl chr30:16,201,589...16,223,662
JBrowse link
G TH tyrosine hydroxylase ISO RGD PMID:20025246 RGD:4139888 NCBI chr18:46,327,136...46,334,973
Ensembl chr18:46,327,137...46,335,602
JBrowse link
dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:20097214 RGD:6903884 NCBI chr23:43,569,658...43,617,113
Ensembl chr23:43,614,035...43,616,238
JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:20097214 RGD:6903884 NCBI chr  X:88,703,551...88,708,451
Ensembl chr  X:88,705,765...88,706,853
JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit ISO RGD PMID:12438507 RGD:704388 NCBI chr 3:36,852,082...37,164,930
Ensembl chr 3:36,852,543...36,978,399
JBrowse link
G CYP2D15 cytochrome P450 family 2 subfamily D member 15 ISO RGD PMID:19818757 RGD:5143981 NCBI chr10:23,255,259...23,259,380
Ensembl chr10:23,255,249...23,259,298
JBrowse link
G DAO D-amino acid oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:18,032,663...18,057,277
Ensembl chr26:18,033,392...18,057,238
JBrowse link
G DDC dopa decarboxylase ISO RGD PMID:12703659 RGD:4139893 NCBI chr18:1,802,239...1,876,714
Ensembl chr18:1,803,273...1,867,616
JBrowse link
G GCH1 GTP cyclohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:30,733,422...30,784,067
Ensembl chr 8:30,732,608...30,784,156
JBrowse link
G GPR37 G protein-coupled receptor 37 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3046856|PMID:15218106) Ensembl
MGI
PMID:15218106 GO_REF:0000107 MGI:3046856 NCBI chr14:11,113,584...11,137,639
Ensembl chr14:11,114,415...11,132,395
JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 acts_upstream_of_or_within ISO (MGI:1203924|PMID:9608532), (MGI:3767764|PMID:16782508) MGI PMID:9608532 PMID:16782508 MGI:1203924 MGI:3767764 NCBI chr36:2,546,237...2,554,559
Ensembl chr36:2,547,421...2,552,780
JBrowse link
G SLC6A3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO (MGI:2386819|PMID:9520487) MGI PMID:9520487 MGI:2386819 NCBI chr34:11,209,118...11,245,456
Ensembl chr34:11,210,939...11,246,742
JBrowse link
G SNCA synuclein alpha acts_upstream_of_or_within ISO (MGI:1352916|PMID:10707987) MGI PMID:10707987 MGI:1352916 NCBI chr32:12,915,871...13,079,338
Ensembl chr32:12,916,215...13,060,383
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISO (MGI:3622848|PMID:16257223) UniProt PMID:16257223 MGI:3622848 NCBI chr38:13,430,832...13,511,655
Ensembl chr38:13,429,148...13,510,242
JBrowse link
G TH tyrosine hydroxylase involved_in IEA UniProt GO_REF:0000041 NCBI chr18:46,327,136...46,334,973
Ensembl chr18:46,327,137...46,335,602
JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TH tyrosine hydroxylase involved_in
acts_upstream_of_or_within
ISO PMID:11943812
(MGI:72094|PMID:7715703), (MGI:77787|PMID:7592982)
(MGI:2386819|PMID:9520487)
RGD
BHF-UCL
MGI
PMID:2427363 PMID:7592982 PMID:7715703 PMID:9520487 PMID:11943812 More... MGI:2386819 MGI:72094 MGI:77787 RGD:1580046 RGD:5129111 RGD:5130972 NCBI chr18:46,327,136...46,334,973
Ensembl chr18:46,327,137...46,335,602
JBrowse link
epinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PNMT phenylethanolamine N-methyltransferase ISO RGD PMID:7914070 RGD:4139902 NCBI chr 9:22,808,505...22,810,587
Ensembl chr 9:22,808,601...22,810,551
JBrowse link
G TH tyrosine hydroxylase involved_in ISO (PMID:12457228) BHF-UCL PMID:12457228 NCBI chr18:46,327,136...46,334,973
Ensembl chr18:46,327,137...46,335,602
JBrowse link
histamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDC histidine decarboxylase involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:2138019|PMID:11478947)
GO_Central
MGI
PMID:11478947 PMID:21873635 MGI:2138019 NCBI chr30:16,201,222...16,223,452
Ensembl chr30:16,201,589...16,223,662
JBrowse link
G PRG3 proteoglycan 3, pro eosinophil major basic protein 2 involved_in ISO (PMID:10318872) UniProt PMID:10318872 NCBI chr18:38,765,682...38,769,711
Ensembl chr18:38,766,095...38,769,711
JBrowse link
norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha acts_upstream_of_or_within ISO (MGI:53940|PMID:4858102)
(MGI:53801|PMID:4405722)
MGI PMID:4405722 PMID:4858102 MGI:53801 MGI:53940 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869
JBrowse link
G DBH dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
IEA
(MGI:1203930|PMID:9603211), (MGI:1332340|PMID:10051631)
(PMID:21873635)
UniProt
MGI
RGD
GO_Central
PMID:9603211 PMID:10051631 PMID:10573542 PMID:21873635 GO_REF:0000024 GO_REF:0000041 MGI:1203930 MGI:1332340 RGD:1625403 NCBI chr 9:50,004,806...50,024,130
Ensembl chr 9:50,004,806...50,024,130
JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO RGD PMID:19457096 RGD:5128877 NCBI chr10:48,550,836...48,636,776
Ensembl chr10:48,551,410...48,634,844
JBrowse link
G GATA3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:1859081|PMID:10835639) MGI PMID:10835639 MGI:1859081 NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760
JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in ISO (MGI:3772428|PMID:18094025) UniProt PMID:18094025 MGI:3772428 NCBI chr24:3,008,387...3,011,186 JBrowse link
G KL klotho ISO RGD PMID:20086041 RGD:10403068 NCBI chr25:7,154,359...7,201,744
Ensembl chr25:7,156,620...7,199,558
JBrowse link
G MOXD1 monooxygenase DBH like 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:25,018,452...25,114,028
Ensembl chr 1:25,018,509...25,112,478
JBrowse link
G TH tyrosine hydroxylase involved_in ISO (PMID:12457228) BHF-UCL PMID:12457228 NCBI chr18:46,327,136...46,334,973
Ensembl chr18:46,327,137...46,335,602
JBrowse link
octopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBH dopamine beta-hydroxylase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:50,004,806...50,024,130
Ensembl chr 9:50,004,806...50,024,130
JBrowse link
G MOXD1 monooxygenase DBH like 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:25,018,452...25,114,028
Ensembl chr 1:25,018,509...25,112,478
JBrowse link
polyamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SAT1 spermidine/spermine N1-acetyltransferase 1 involved_in ISO (PMID:15283699) UniProt PMID:15283699 NCBI chr  X:19,461,945...19,464,209
Ensembl chr  X:19,463,109...19,464,116
JBrowse link
G SAT2 spermidine/spermine N1-acetyltransferase family member 2 NOT|involved_in ISO (PMID:15283699) UniProt PMID:15283699 NCBI chr 5:32,534,302...32,536,022
Ensembl chr 5:32,534,310...32,535,846
JBrowse link
positive regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPAS1 endothelial PAS domain protein 1 ISO RGD PMID:19457096 RGD:5128877 NCBI chr10:48,550,836...48,636,776
Ensembl chr10:48,551,410...48,634,844
JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in ISO (PMID:19703902) ParkinsonsUK-UCL PMID:19703902 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303
JBrowse link
G VPS35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) ParkinsonsUK-UCL PMID:26203154 MGI:5694519 NCBI chr15:8,428,073...8,454,601
Ensembl chr15:8,428,172...8,454,049
JBrowse link
positive regulation of spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAOX polyamine oxidase involved_in ISO (PMID:16354669) UniProt PMID:16354669
positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAND2 heart and neural crest derivatives expressed 2 involved_in ISO (MGI:4413411|PMID:19008477) BHF-UCL PMID:19008477 MGI:4413411 NCBI chr25:24,140,496...24,143,143
Ensembl chr25:24,141,243...24,152,958
JBrowse link
putrescine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ODC1 ornithine decarboxylase 1 ISO RGD PMID:1415709 PMID:10430362 RGD:1578320 RGD:7242912 NCBI chr17:7,368,699...7,376,970
Ensembl chr17:7,369,232...7,376,975
JBrowse link
G PAOX polyamine oxidase involved_in ISO (PMID:16354669) UniProt PMID:16354669
putrescine biosynthetic process from arginine, using agmatinase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGMAT agmatinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:81,980,959...81,990,377
Ensembl chr 2:81,981,376...81,989,916
JBrowse link
putrescine biosynthetic process from ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AZIN1 antizyme inhibitor 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:4,363,996...4,396,069
Ensembl chr13:4,361,340...4,396,040
JBrowse link
G AZIN2 antizyme inhibitor 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:68,288,554...68,323,710
Ensembl chr 2:68,286,195...68,323,710
JBrowse link
G ODC1 ornithine decarboxylase 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:7,368,699...7,376,970
Ensembl chr17:7,369,232...7,376,975
JBrowse link
regulation of polyamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NNMT nicotinamide N-methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:19,026,514...19,044,154
Ensembl chr 5:19,026,556...19,044,016
JBrowse link
spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMD1 adenosylmethionine decarboxylase 1 acts_upstream_of_or_within ISO (MGI:3584197|PMID:11856372) RGD
MGI
PMID:1415709 PMID:10430362 PMID:10712236 PMID:11856372 MGI:3584197 RGD:1578320 RGD:7242911 RGD:7242912 NCBI chr12:67,432,871...67,453,791
Ensembl chr12:67,448,141...67,451,696
JBrowse link
G SRM spermidine synthase involved_in ISO (PMID:17585781) RGD
UniProt
PMID:8494549 PMID:12843627 PMID:16931179 PMID:17585781 RGD:1359042 RGD:7242920 RGD:7242928 NCBI chr 2:84,968,833...84,973,111
Ensembl chr 2:84,967,570...84,973,087
JBrowse link
spermine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMD1 adenosylmethionine decarboxylase 1 acts_upstream_of_or_within ISO (MGI:3584197|PMID:11856372) RGD
MGI
PMID:1415709 PMID:10430362 PMID:10712236 PMID:11856372 MGI:3584197 RGD:1578320 RGD:7242911 RGD:7242912 NCBI chr12:67,432,871...67,453,791
Ensembl chr12:67,448,141...67,451,696
JBrowse link
G SMS spermine synthase ISO RGD PMID:8494549 RGD:7242928 NCBI chr  X:17,749,020...17,803,351
Ensembl chr  X:17,749,530...17,802,999
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13875
    metabolic process 8978
      nitrogen compound metabolic process 7494
        organonitrogen compound metabolic process 5124
          amine metabolic process 114
            amine biosynthetic process 38
              cellular biogenic amine biosynthetic process + 38
paths to the root