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ONTOLOGY REPORT - ANNOTATIONS


Term:amine metabolic process
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Accession:GO:0009308 term browser browse the term
Definition:The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
Synonyms:exact_synonym: amine metabolism


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amine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AOC1 amine oxidase copper containing 1 IEA
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000104 NCBI chr 7:150,824,875...150,861,504
Ensembl chr 7:150,824,627...150,861,504
JBrowse link
G AOC2 amine oxidase copper containing 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:42,844,580...42,850,707
Ensembl chr17:42,844,580...42,850,707
JBrowse link
G AOC3 amine oxidase copper containing 3 IDA
IBA
IEA
(PMID:9653080)
(PMID:21873635)
UniProtKB
GO_Central
PMID:9653080, PMID:21873635 GO_REF:0000104 NCBI chr17:42,851,182...42,858,130
Ensembl chr17:42,851,184...42,858,130
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IEA Ensembl GO_REF:0000107 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G INMT indolethylamine N-methyltransferase IDA (PMID:10552930) UniProtKB PMID:10552930 NCBI chr 7:30,752,135...30,757,602
Ensembl chr 7:30,697,985...30,757,602
JBrowse link
G SULT1A1 sulfotransferase family 1A member 1 TAS (PMID:8661000) PINC PMID:8661000 NCBI chr16:28,605,587...28,623,395
Ensembl chr16:28,605,196...28,623,625
JBrowse link
G SULT1C2 sulfotransferase family 1C member 2 TAS (PMID:9169148) PINC PMID:9169148 NCBI chr 2:108,288,895...108,309,915
Ensembl chr 2:108,288,639...108,309,915
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 IDA (PMID:23474851) UniProtKB PMID:23474851 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
JBrowse link
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFMID arylformamidase IEA UniProt GO_REF:0000104 NCBI chr17:78,185,102...78,207,702
Ensembl chr17:78,187,317...78,207,701
JBrowse link
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:42,767,087...42,801,002
Ensembl chr 2:42,767,089...42,792,593
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790
JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:39,934,955...40,016,391
Ensembl chr 8:39,934,614...40,016,391
JBrowse link
G KMO kynurenine 3-monooxygenase IEA UniProt GO_REF:0000104 NCBI chr 1:241,531,883...241,595,642
Ensembl chr 1:241,532,134...241,595,642
JBrowse link
G KYNU kynureninase IEA UniProt GO_REF:0000104 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
JBrowse link
amine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SULT1A2 sulfotransferase family 1A member 2 TAS (PMID:9119390) PINC PMID:9119390 NCBI chr16:28,591,943...28,597,070
Ensembl chr16:28,591,943...28,597,050
JBrowse link
benzylpenicillin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC2 ATP binding cassette subfamily C member 2 IEA Ensembl GO_REF:0000107 NCBI chr10:99,782,602...99,853,741
Ensembl chr10:99,782,640...99,852,594
JBrowse link
cellular biogenic amine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAOA monoamine oxidase A TAS (PMID:8211186) PINC PMID:8211186 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,824
JBrowse link
G MECP2 methyl-CpG binding protein 2 IEA Ensembl GO_REF:0000107 NCBI chr  X:154,021,573...154,097,717
Ensembl chr  X:154,021,573...154,137,103
JBrowse link
G SULT1B1 sulfotransferase family 1B member 1 TAS (PMID:9443824) PINC PMID:9443824 NCBI chr 4:69,721,167...69,760,644
Ensembl chr 4:69,721,167...69,787,961
JBrowse link
choline catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 TAS Reactome Reactome:R-HSA-6798163 NCBI chr 5:126,541,841...126,595,219
Ensembl chr 5:126,531,200...126,595,362
JBrowse link
G BHMT betaine--homocysteine S-methyltransferase TAS Reactome Reactome:R-HSA-6798163 NCBI chr 5:79,111,809...79,132,288
Ensembl chr 5:79,111,809...79,132,288
JBrowse link
G CHDH choline dehydrogenase TAS Reactome Reactome:R-HSA-6798163 NCBI chr 3:53,812,335...53,846,464
Ensembl chr 3:53,812,335...53,846,419
JBrowse link
G DMGDH dimethylglycine dehydrogenase TAS
IMP
(PMID:10102904) Reactome
UniProtKB
PMID:10102904 Reactome:R-HSA-6798163 NCBI chr 5:78,997,564...79,069,674
Ensembl chr 5:78,997,564...79,236,038
JBrowse link
G SARDH sarcosine dehydrogenase TAS Reactome Reactome:R-HSA-6798163 NCBI chr 9:133,663,074...133,739,958
Ensembl chr 9:133,663,560...133,739,955
JBrowse link
G SLC44A1 solute carrier family 44 member 1 TAS Reactome Reactome:R-HSA-6798163 NCBI chr 9:105,244,608...105,439,775
Ensembl chr 9:105,244,622...105,439,171
JBrowse link
ethanolamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHKA choline kinase alpha IEA Ensembl GO_REF:0000107 NCBI chr11:68,052,859...68,121,389
Ensembl chr11:68,052,859...68,121,444
JBrowse link
G GDE1 glycerophosphodiester phosphodiesterase 1 ISS UniProt GO_REF:0000024 NCBI chr16:19,501,693...19,522,098
Ensembl chr16:19,501,693...19,522,123
JBrowse link
histamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDC histidine decarboxylase TAS
IBA
IDA
IEA
(PMID:21873635)
(PMID:22767596)
Reactome
GO_Central
UniProtKB
PMID:21873635, PMID:22767596 GO_REF:0000041, Reactome:R-HSA-977301 NCBI chr15:50,241,945...50,266,049
Ensembl chr15:50,241,947...50,265,965
JBrowse link
G PRG3 proteoglycan 3, pro eosinophil major basic protein 2 IDA (PMID:10318872) UniProtKB PMID:10318872 NCBI chr11:57,376,769...57,381,150
Ensembl chr11:57,376,769...57,381,150
JBrowse link
histamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNMT histamine N-methyltransferase IDA (PMID:26206890) UniProtKB PMID:26206890 NCBI chr 2:137,964,068...138,016,364
Ensembl chr 2:137,964,020...138,016,364
JBrowse link
histamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDC histidine decarboxylase ISO RGD PMID:5898, PMID:4449071, PMID:7075603, PMID:9525922 RGD:2303726, RGD:2303727, RGD:2303728, RGD:2303735 NCBI chr15:50,241,945...50,266,049
Ensembl chr15:50,241,947...50,265,965
JBrowse link
G HNMT histamine N-methyltransferase IMP (PMID:23505051) ARUK-UCL PMID:23505051 NCBI chr 2:137,964,068...138,016,364
Ensembl chr 2:137,964,020...138,016,364
JBrowse link
G SLC22A3 solute carrier family 22 member 3 TAS (PMID:23505051) ARUK-UCL PMID:23505051 NCBI chr 6:160,348,378...160,454,982
Ensembl chr 6:160,348,378...160,452,577
JBrowse link
G SLC29A4 solute carrier family 29 member 4 TAS (PMID:23505051) ARUK-UCL PMID:23505051 NCBI chr 7:5,274,311...5,306,912
Ensembl chr 7:5,274,369...5,306,870
JBrowse link
G TRH thyrotropin releasing hormone IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:129,974,720...129,977,935
Ensembl chr 3:129,974,688...129,977,935
JBrowse link
indolalkylamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AANAT aralkylamine N-acetyltransferase TAS Reactome Reactome:R-HSA-209931 NCBI chr17:76,453,351...76,470,797
Ensembl chr17:76,453,351...76,470,117
JBrowse link
G ASMT acetylserotonin O-methyltransferase TAS Reactome Reactome:R-HSA-209931 NCBI chr  Y:1,595,455...1,643,081
NCBI chr  X:1,595,455...1,643,081
Ensembl chr  X:1,615,059...1,643,081
JBrowse link
G DDC dopa decarboxylase TAS Reactome Reactome:R-HSA-209931 NCBI chr 7:50,458,436...50,565,460
Ensembl chr 7:50,458,436...50,565,405
JBrowse link
G TPH1 tryptophan hydroxylase 1 TAS Reactome Reactome:R-HSA-209931 NCBI chr11:18,017,555...18,046,269
Ensembl chr11:18,017,564...18,042,426
JBrowse link
G TPH2 tryptophan hydroxylase 2 TAS Reactome Reactome:R-HSA-209931 NCBI chr12:71,938,845...72,032,440
Ensembl chr12:71,938,845...72,186,618
JBrowse link
N-acylethanolamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD4 abhydrolase domain containing 4, N-acyl phospholipase B ISO (MGI:MGI:3695251|PMID:16818490) MGI PMID:16818490 MGI:MGI:3695251 NCBI chr14:22,598,238...22,612,864
Ensembl chr14:22,598,237...22,613,215
JBrowse link
G GDE1 glycerophosphodiester phosphodiesterase 1 ISS UniProtKB
UniProt
GO_REF:0000024 NCBI chr16:19,501,693...19,522,098
Ensembl chr16:19,501,693...19,522,123
JBrowse link
G GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 IBA
IMP
(PMID:21873635)
(PMID:25596343), (PMID:27637550)
GO_Central
MGI
PMID:21873635, PMID:25596343, PMID:27637550 NCBI chr17:59,220,470...59,275,970
Ensembl chr17:59,220,467...59,275,970
JBrowse link
G GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 IMP (PMID:27637550) UniProt PMID:27637550 NCBI chr16:30,104,810...30,113,537
Ensembl chr16:30,104,810...30,113,537
JBrowse link
G NAAA N-acylethanolamine acid amidase IDA (PMID:15655246), (PMID:30301806) UniProt PMID:15655246, PMID:30301806 NCBI chr 4:75,910,655...75,941,013
Ensembl chr 4:75,913,660...75,941,013
JBrowse link
G NAPEPLD N-acyl phosphatidylethanolamine phospholipase D IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:103,099,776...103,150,001
Ensembl chr 7:103,099,776...103,149,560
JBrowse link
negative regulation of arginine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 IDA (PMID:19278978) BHF-UCL PMID:19278978 NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,787...203,744,081
Ensembl chr 1:203,626,787...203,744,081
JBrowse link
negative regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO (MGI:MGI:54307|PMID:17511) MGI PMID:17511 MGI:MGI:54307 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,656...78,050,395
JBrowse link
negative regulation of citrulline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 IDA (PMID:19278978) BHF-UCL PMID:19278978 NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,787...203,744,081
Ensembl chr 1:203,626,787...203,744,081
JBrowse link
negative regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COMT catechol-O-methyltransferase IEA Ensembl GO_REF:0000107 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,733...19,969,975
Ensembl chr22:19,941,733...19,969,975
JBrowse link
G HTR2C 5-hydroxytryptamine receptor 2C ISO RGD PMID:17018023 RGD:1625003 NCBI chr  X:114,584,078...114,910,061
Ensembl chr  X:114,584,078...114,910,061
JBrowse link
G ITGAM integrin subunit alpha M ISS ARUK-UCL GO_REF:0000024 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
JBrowse link
G ITGB2 integrin subunit beta 2 NAS (PMID:18981141) ARUK-UCL PMID:18981141 NCBI chr21:44,885,949...44,928,815
Ensembl chr21:44,885,953...44,931,989
JBrowse link
G SNCA synuclein alpha IEA Ensembl GO_REF:0000107 NCBI chr 4:89,724,099...89,838,324
Ensembl chr 4:89,700,345...89,838,315
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
negative regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATCAY ATCAY kinesin light chain interacting caytaxin IDA (PMID:16899818) UniProtKB PMID:16899818 NCBI chr19:3,880,685...3,928,082
Ensembl chr19:3,879,864...3,928,082
JBrowse link
nor-spermidine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SAT2 spermidine/spermine N1-acetyltransferase family member 2 IDA (PMID:12803540) UniProtKB PMID:12803540 NCBI chr17:7,626,234...7,627,878
Ensembl chr17:7,626,234...7,627,876
JBrowse link
octopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBH dopamine beta-hydroxylase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329
JBrowse link
G MOXD1 monooxygenase DBH like 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:132,296,055...132,401,520
Ensembl chr 6:132,296,055...132,401,475
JBrowse link
G MOXD2P monooxygenase DBH like 2, pseudogene IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:142,240,737...142,247,067
Ensembl chr 7:142,240,740...142,247,067
JBrowse link
octopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBH dopamine beta-hydroxylase ISO RGD PMID:11521740 RGD:1625401 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329
JBrowse link
phenylethylamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAOA monoamine oxidase A ISO Y402A, Y407A, Y410A had an impact on the properties of the protein while Y402F, Y410F had little effect; the residues are near the C406 FAD binding site RGD PMID:11754741 RGD:1600709 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,824
JBrowse link
polyamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC005258.1 novel protein, readthrough between OAZ1 and SPPL2B IEA UniProt GO_REF:0000043 Ensembl chr19:2,269,525...2,341,172 JBrowse link
G AZIN1 antizyme inhibitor 1 IEA InterPro GO_REF:0000002 NCBI chr 8:102,826,302...102,864,200
Ensembl chr 8:102,826,308...102,893,864
JBrowse link
G AZIN2 antizyme inhibitor 2 IEA InterPro GO_REF:0000002 NCBI chr 1:33,081,152...33,162,288
Ensembl chr 1:33,081,104...33,123,492
JBrowse link
G OAZ1 ornithine decarboxylase antizyme 1 IEA UniProt GO_REF:0000043 NCBI chr19:2,269,486...2,273,488
Ensembl chr19:2,269,509...2,273,490
JBrowse link
G OAZ2 ornithine decarboxylase antizyme 2 IEA UniProt GO_REF:0000043 NCBI chr15:64,687,574...64,703,281
Ensembl chr15:64,687,573...64,703,281
JBrowse link
G OAZ3 ornithine decarboxylase antizyme 3 IEA UniProt GO_REF:0000043 NCBI chr 1:151,762,969...151,771,330
Ensembl chr 1:151,762,899...151,771,334
JBrowse link
G ODC1 ornithine decarboxylase 1 IEA InterPro GO_REF:0000002 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
JBrowse link
G PAOX polyamine oxidase TAS Reactome Reactome:R-HSA-351200 NCBI chr10:133,379,262...133,391,694
Ensembl chr10:133,380,017...133,420,271
Ensembl chr10:133,380,017...133,420,271
JBrowse link
G SAT1 spermidine/spermine N1-acetyltransferase 1 TAS
IDA
(PMID:15283699) Reactome
UniProt
PMID:15283699 Reactome:R-HSA-351200 NCBI chr  X:23,783,158...23,786,223
Ensembl chr  X:23,783,173...23,786,226
JBrowse link
G SAT2 spermidine/spermine N1-acetyltransferase family member 2 NOT IDA (PMID:15283699) UniProt PMID:15283699 NCBI chr17:7,626,234...7,627,878
Ensembl chr17:7,626,234...7,627,876
JBrowse link
G SMOX spermine oxidase TAS Reactome Reactome:R-HSA-351200 NCBI chr20:4,148,828...4,187,732
Ensembl chr20:4,120,980...4,187,747
JBrowse link
G SRM spermidine synthase IEA
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000104 NCBI chr 1:11,054,589...11,060,053
Ensembl chr 1:11,054,584...11,060,020
JBrowse link
polyamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAOX polyamine oxidase IDA (PMID:12477380) UniProtKB PMID:12477380 NCBI chr10:133,379,262...133,391,694
Ensembl chr10:133,380,017...133,420,271
Ensembl chr10:133,380,017...133,420,271
JBrowse link
G SAT1 spermidine/spermine N1-acetyltransferase 1 ISO RGD PMID:15541750 RGD:7244190 NCBI chr  X:23,783,158...23,786,223
Ensembl chr  X:23,783,173...23,786,226
JBrowse link
G SMOX spermine oxidase IDA (PMID:12477380) UniProtKB PMID:12477380 NCBI chr20:4,148,828...4,187,732
Ensembl chr20:4,120,980...4,187,747
JBrowse link
polyamine deacetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC10 histone deacetylase 10 IDA (PMID:28516954) UniProt PMID:28516954 NCBI chr22:50,245,183...50,251,265
Ensembl chr22:50,245,183...50,251,405
JBrowse link
G HDAC6 histone deacetylase 6 NOT IDA (PMID:28516954) UniProt PMID:28516954 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982
JBrowse link
polyamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMD1 adenosylmethionine decarboxylase 1 TAS Reactome Reactome:R-HSA-351202 NCBI chr 6:110,814,617...110,895,713
Ensembl chr 6:110,874,770...110,898,879
JBrowse link
G OAZ2 ornithine decarboxylase antizyme 2 IEA
TAS
(PMID:9428668) InterPro
PINC
PMID:9428668 GO_REF:0000002 NCBI chr15:64,687,574...64,703,281
Ensembl chr15:64,687,573...64,703,281
JBrowse link
G ODC1 ornithine decarboxylase 1 TAS Reactome Reactome:R-HSA-351202 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
JBrowse link
G SAT1 spermidine/spermine N1-acetyltransferase 1 ISO RGD PMID:11172929 RGD:1599544 NCBI chr  X:23,783,158...23,786,223
Ensembl chr  X:23,783,173...23,786,226
JBrowse link
G SMS spermine synthase TAS Reactome Reactome:R-HSA-351202 NCBI chr  X:21,940,709...21,994,837
Ensembl chr  X:21,940,709...21,994,837
JBrowse link
G SRM spermidine synthase TAS Reactome Reactome:R-HSA-351202 NCBI chr 1:11,054,589...11,060,053
Ensembl chr 1:11,054,584...11,060,020
JBrowse link
positive regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PEBP1 phosphatidylethanolamine binding protein 1 ISO RGD PMID:8888012 RGD:2302806 NCBI chr12:118,136,124...118,145,584
Ensembl chr12:118,136,124...118,145,584
JBrowse link
positive regulation of ammonia assimilation cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1H4 nuclear receptor subfamily 1 group H member 4 IEA Ensembl GO_REF:0000107 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
JBrowse link
positive regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPAS1 endothelial PAS domain protein 1 ISO RGD PMID:19457096 RGD:5128877 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G PARK7 Parkinsonism associated deglycase IC
IDA
(PMID:16731528)
(PMID:19703902)
ParkinsonsUK-UCL PMID:16731528, PMID:19703902 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
G VPS35 VPS35 retromer complex component IEA Ensembl GO_REF:0000107 NCBI chr16:46,656,132...46,689,194
Ensembl chr16:46,656,132...46,689,518
JBrowse link
positive regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase IEA Ensembl GO_REF:0000107 NCBI chr16:8,674,617...8,784,575
Ensembl chr16:8,674,596...8,784,575
JBrowse link
G GPR37 G protein-coupled receptor 37 IEA Ensembl GO_REF:0000107 NCBI chr 7:124,743,885...124,765,792
Ensembl chr 7:124,743,885...124,765,792
JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 IMP (PMID:8643611) UniProtKB PMID:8643611 NCBI chr  X:134,460,165...134,500,668
Ensembl chr  X:134,460,165...134,520,513
JBrowse link
G MAOB monoamine oxidase B IEA Ensembl GO_REF:0000107 NCBI chr  X:43,766,610...43,882,450
Ensembl chr  X:43,766,610...43,882,450
JBrowse link
G NPY neuropeptide Y ISO RGD PMID:19579268 RGD:10448966 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862
JBrowse link
positive regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISS (PMID:21757002) BHF-UCL PMID:21757002 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
JBrowse link
positive regulation of homocysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COMT catechol-O-methyltransferase IEA Ensembl GO_REF:0000107 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,733...19,969,975
Ensembl chr22:19,941,733...19,969,975
JBrowse link
positive regulation of L-dopa biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase IMP (PMID:16731528) ParkinsonsUK-UCL PMID:16731528 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
positive regulation of spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAOX polyamine oxidase IDA (PMID:16354669) UniProtKB PMID:16354669 NCBI chr10:133,379,262...133,391,694
Ensembl chr10:133,380,017...133,420,271
Ensembl chr10:133,380,017...133,420,271
JBrowse link
putrescine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SAT2 spermidine/spermine N1-acetyltransferase family member 2 IDA (PMID:12803540) UniProtKB PMID:12803540 NCBI chr17:7,626,234...7,627,878
Ensembl chr17:7,626,234...7,627,876
JBrowse link
putrescine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ODC1 ornithine decarboxylase 1 ISO RGD PMID:1415709, PMID:10430362 RGD:1578320, RGD:7242912 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
JBrowse link
G PAOX polyamine oxidase IDA (PMID:16354669) UniProtKB PMID:16354669 NCBI chr10:133,379,262...133,391,694
Ensembl chr10:133,380,017...133,420,271
Ensembl chr10:133,380,017...133,420,271
JBrowse link
putrescine biosynthetic process from arginine, using agmatinase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGMAT agmatinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:15,571,699...15,585,051
Ensembl chr 1:15,571,699...15,585,051
JBrowse link
putrescine biosynthetic process from ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AZIN1 antizyme inhibitor 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:102,826,302...102,864,200
Ensembl chr 8:102,826,308...102,893,864
JBrowse link
G AZIN2 antizyme inhibitor 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:33,081,152...33,162,288
Ensembl chr 1:33,081,104...33,123,492
JBrowse link
G ODC1 ornithine decarboxylase 1 IEA
IBA
ISS
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024, GO_REF:0000041 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
JBrowse link
putrescine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAOX polyamine oxidase IDA (PMID:16354669) UniProtKB PMID:16354669 NCBI chr10:133,379,262...133,391,694
Ensembl chr10:133,380,017...133,420,271
Ensembl chr10:133,380,017...133,420,271
JBrowse link
G SAT1 spermidine/spermine N1-acetyltransferase 1 IEA UniProtKB GO_REF:0000041 NCBI chr  X:23,783,158...23,786,223
Ensembl chr  X:23,783,173...23,786,226
JBrowse link
G SAT2 spermidine/spermine N1-acetyltransferase family member 2 IEA UniProtKB GO_REF:0000041 NCBI chr17:7,626,234...7,627,878
Ensembl chr17:7,626,234...7,627,876
JBrowse link
putrescine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AOC1 amine oxidase copper containing 1 IMP (PMID:8144586) UniProt PMID:8144586 NCBI chr 7:150,824,875...150,861,504
Ensembl chr 7:150,824,627...150,861,504
JBrowse link
regulation of 'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACMSD aminocarboxymuconate semialdehyde decarboxylase TAS (PMID:12140278), (PMID:19843166) ParkinsonsUK-UCL PMID:12140278, PMID:19843166 NCBI chr 2:134,838,319...134,902,906
Ensembl chr 2:134,838,616...134,902,034
JBrowse link
regulation of acetylcholine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FSHR follicle stimulating hormone receptor IEA Ensembl GO_REF:0000107 NCBI chr 2:48,953,161...49,154,527
Ensembl chr 2:48,962,157...49,154,527
Ensembl chr 2:48,962,157...49,154,527
JBrowse link
regulation of arginine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISS UniProt GO_REF:0000024 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,456,371...28,492,098
Ensembl chr16:28,456,371...28,492,098
JBrowse link
regulation of arginine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FH fumarate hydratase ISS UniProt GO_REF:0000024 NCBI chr 1:241,497,603...241,519,755
Ensembl chr 1:241,497,603...241,519,761
Ensembl chr 1:241,497,603...241,519,761
JBrowse link
G SLC7A7 solute carrier family 7 member 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:22,773,222...22,819,796
Ensembl chr14:22,773,222...22,829,820
JBrowse link
regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VHL von Hippel-Lindau tumor suppressor ISO RGD PMID:11912140 RGD:619592 NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,008...10,152,220
Ensembl chr 3:10,141,008...10,152,220
JBrowse link
regulation of cellular amino acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AZIN1 antizyme inhibitor 1 TAS Reactome Reactome:R-HSA-350562 NCBI chr 8:102,826,302...102,864,200
Ensembl chr 8:102,826,308...102,893,864
JBrowse link
G INS insulin IMP (PMID:3553851) BHF-UCL PMID:3553851 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,341
Ensembl chr11:2,159,779...2,161,341
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 TAS Reactome Reactome:R-HSA-350562 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G OAZ1 ornithine decarboxylase antizyme 1 TAS Reactome Reactome:R-HSA-350562 NCBI chr19:2,269,486...2,273,488
Ensembl chr19:2,269,509...2,273,490
JBrowse link
G OAZ2 ornithine decarboxylase antizyme 2 TAS Reactome Reactome:R-HSA-350562 NCBI chr15:64,687,574...64,703,281
Ensembl chr15:64,687,573...64,703,281
JBrowse link
G OAZ3 ornithine decarboxylase antizyme 3 TAS Reactome Reactome:R-HSA-350562 NCBI chr 1:151,762,969...151,771,330
Ensembl chr 1:151,762,899...151,771,334
JBrowse link
G ODC1 ornithine decarboxylase 1 TAS Reactome Reactome:R-HSA-350562 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
JBrowse link
G PSMA1 proteasome 20S subunit alpha 1 TAS Reactome Reactome:R-HSA-350562 NCBI chr11:14,504,876...14,643,662
Ensembl chr11:14,504,874...14,643,635
JBrowse link
G PSMA2 proteasome 20S subunit alpha 2 TAS Reactome Reactome:R-HSA-350562 NCBI chr 7:42,916,861...42,932,174
Ensembl chr 7:42,909,273...42,932,174
Ensembl chr 7:42,909,273...42,932,174
JBrowse link
G PSMA3 proteasome 20S subunit alpha 3 TAS Reactome Reactome:R-HSA-350562 NCBI chr14:58,244,843...58,272,004
Ensembl chr14:58,244,843...58,272,012
JBrowse link
G PSMA4 proteasome 20S subunit alpha 4 TAS Reactome Reactome:R-HSA-350562 NCBI chr15:78,540,405...78,552,417
Ensembl chr15:78,540,405...78,552,417
JBrowse link
G PSMA5 proteasome 20S subunit alpha 5 TAS Reactome Reactome:R-HSA-350562 NCBI chr 1:109,399,042...109,426,448
Ensembl chr 1:109,399,042...109,426,448
JBrowse link
G PSMA6 proteasome 20S subunit alpha 6 TAS Reactome Reactome:R-HSA-350562 NCBI chr14:35,278,558...35,317,493
Ensembl chr14:35,278,633...35,317,493
JBrowse link
G PSMA7 proteasome 20S subunit alpha 7 TAS Reactome Reactome:R-HSA-350562 NCBI chr20:62,136,733...62,143,394
Ensembl chr20:62,136,733...62,143,440
JBrowse link
G PSMA8 proteasome 20S subunit alpha 8 TAS Reactome Reactome:R-HSA-350562 NCBI chr18:26,133,869...26,193,355
Ensembl chr18:26,133,852...26,193,355
JBrowse link
G PSMB1 proteasome 20S subunit beta 1 TAS Reactome Reactome:R-HSA-350562 NCBI chr 6:170,535,120...170,553,307
Ensembl chr 6:170,535,120...170,553,307
JBrowse link
G PSMB10 proteasome 20S subunit beta 10 TAS Reactome Reactome:R-HSA-350562 NCBI chr16:67,934,506...67,936,850
Ensembl chr16:67,934,506...67,936,864
JBrowse link
G PSMB11 proteasome subunit beta 11 TAS Reactome Reactome:R-HSA-350562 NCBI chr14:23,042,212...23,044,060
Ensembl chr14:23,042,212...23,044,060
JBrowse link
G PSMB2 proteasome 20S subunit beta 2 TAS Reactome Reactome:R-HSA-350562 NCBI chr 1:35,599,541...35,641,526
Ensembl chr 1:35,599,541...35,641,526
JBrowse link
G PSMB3 proteasome 20S subunit beta 3 TAS Reactome Reactome:R-HSA-350562 NCBI chr17:38,752,741...38,764,225
Ensembl chr17:38,752,741...38,764,225
JBrowse link
G PSMB4 proteasome 20S subunit beta 4 TAS Reactome Reactome:R-HSA-350562 NCBI chr 1:151,399,573...151,401,937
Ensembl chr 1:151,399,560...151,401,937
JBrowse link
G PSMB5 proteasome 20S subunit beta 5 TAS Reactome Reactome:R-HSA-350562 NCBI chr14:23,025,851...23,035,220
Ensembl chr14:23,016,543...23,035,230
JBrowse link
G PSMB6 proteasome 20S subunit beta 6 TAS Reactome Reactome:R-HSA-350562 NCBI chr17:4,796,164...4,798,495
Ensembl chr17:4,796,144...4,798,502
JBrowse link
G PSMB7 proteasome 20S subunit beta 7 TAS Reactome Reactome:R-HSA-350562 NCBI chr 9:124,353,465...124,415,442
Ensembl chr 9:124,353,465...124,415,444
JBrowse link
G PSMB8 proteasome 20S subunit beta 8 TAS Reactome Reactome:R-HSA-350562 NCBI chr 6:32,840,717...32,844,679
Ensembl chr 6:32,840,717...32,844,679
JBrowse link
G PSMB9 proteasome 20S subunit beta 9 TAS Reactome Reactome:R-HSA-350562 NCBI chr 6:32,854,192...32,859,851
Ensembl chr 6:32,844,136...32,859,851
JBrowse link
G PSMC1 proteasome 26S subunit, ATPase 1 TAS Reactome Reactome:R-HSA-350562 NCBI chr14:90,256,553...90,275,429
Ensembl chr14:90,256,527...90,275,429
JBrowse link
G PSMC2 proteasome 26S subunit, ATPase 2 TAS Reactome Reactome:R-HSA-350562 NCBI chr 7:103,344,405...103,369,395
Ensembl chr 7:103,344,254...103,369,395
JBrowse link
G PSMC3 proteasome 26S subunit, ATPase 3 TAS Reactome Reactome:R-HSA-350562 NCBI chr11:47,418,775...47,426,473
Ensembl chr11:47,418,769...47,426,473
JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 TAS Reactome Reactome:R-HSA-350562 NCBI chr19:39,971,150...39,981,764
Ensembl chr19:39,971,165...39,981,764
JBrowse link
G PSMC5 proteasome 26S subunit, ATPase 5 TAS Reactome Reactome:R-HSA-350562 NCBI chr17:63,827,431...63,832,019
Ensembl chr17:63,827,152...63,832,026
JBrowse link
G PSMC6 proteasome 26S subunit, ATPase 6 TAS Reactome Reactome:R-HSA-350562 NCBI chr14:52,707,163...52,728,590
Ensembl chr14:52,707,178...52,728,590
JBrowse link
G PSMD1 proteasome 26S subunit, non-ATPase 1 TAS Reactome Reactome:R-HSA-350562 NCBI chr 2:231,056,867...231,172,827
Ensembl chr 2:231,056,864...231,172,827
JBrowse link
G PSMD10 proteasome 26S subunit, non-ATPase 10 TAS Reactome Reactome:R-HSA-350562 NCBI chr  X:108,084,207...108,091,542
Ensembl chr  X:108,084,207...108,091,549
JBrowse link
G PSMD11 proteasome 26S subunit, non-ATPase 11 TAS Reactome Reactome:R-HSA-350562 NCBI chr17:32,444,510...32,483,319
Ensembl chr17:32,444,379...32,483,319
JBrowse link
G PSMD12 proteasome 26S subunit, non-ATPase 12 TAS Reactome Reactome:R-HSA-350562 NCBI chr17:67,337,916...67,366,598
Ensembl chr17:67,337,916...67,366,605
JBrowse link
G PSMD13 proteasome 26S subunit, non-ATPase 13 TAS Reactome Reactome:R-HSA-350562 NCBI chr11:236,972...252,984
Ensembl chr11:236,966...252,984
JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 TAS Reactome Reactome:R-HSA-350562 NCBI chr 2:161,308,425...161,411,717
Ensembl chr 2:161,308,425...161,411,717
JBrowse link
G PSMD2 proteasome 26S subunit, non-ATPase 2 TAS Reactome Reactome:R-HSA-350562 NCBI chr 3:184,299,241...184,309,050
Ensembl chr 3:184,299,198...184,309,050
JBrowse link
G PSMD3 proteasome 26S subunit, non-ATPase 3 TAS Reactome Reactome:R-HSA-350562 NCBI chr17:39,980,807...39,997,959
Ensembl chr17:39,980,807...39,997,959
JBrowse link
G PSMD4 proteasome 26S subunit, non-ATPase 4 TAS Reactome Reactome:R-HSA-350562 NCBI chr 1:151,254,734...151,267,479
Ensembl chr 1:151,254,703...151,267,479
Ensembl chr 1:151,254,703...151,267,479
JBrowse link
G PSMD5 proteasome 26S subunit, non-ATPase 5 TAS Reactome Reactome:R-HSA-350562 NCBI chr 9:120,816,053...120,842,922
Ensembl chr 9:120,815,496...120,842,951
JBrowse link
G PSMD6 proteasome 26S subunit, non-ATPase 6 TAS Reactome Reactome:R-HSA-350562 NCBI chr 3:64,010,551...64,024,007
Ensembl chr 3:64,010,550...64,024,010
Ensembl chr 3:64,010,550...64,024,010
JBrowse link
G PSMD7 proteasome 26S subunit, non-ATPase 7 TAS Reactome Reactome:R-HSA-350562 NCBI chr16:74,296,814...74,306,288
Ensembl chr16:74,296,814...74,306,288
JBrowse link
G PSMD8 proteasome 26S subunit, non-ATPase 8 TAS Reactome Reactome:R-HSA-350562 NCBI chr19:38,374,571...38,383,824
Ensembl chr19:38,374,536...38,383,824
JBrowse link
G PSMD9 proteasome 26S subunit, non-ATPase 9 TAS Reactome Reactome:R-HSA-350562 NCBI chr12:121,888,790...121,918,297
Ensembl chr12:121,888,809...121,921,470
Ensembl chr12:121,888,809...121,921,470
JBrowse link
G PSME1 proteasome activator subunit 1 TAS Reactome Reactome:R-HSA-350562 NCBI chr14:24,136,194...24,138,962
Ensembl chr14:24,136,163...24,138,967
JBrowse link
G PSME2 proteasome activator subunit 2 TAS Reactome Reactome:R-HSA-350562 NCBI chr14:24,143,365...24,146,646
Ensembl chr14:24,143,362...24,147,570
JBrowse link
G PSME3 proteasome activator subunit 3 TAS Reactome Reactome:R-HSA-350562 NCBI chr17:42,833,397...42,843,760
Ensembl chr17:42,824,385...42,843,760
JBrowse link
G PSME4 proteasome activator subunit 4 TAS Reactome Reactome:R-HSA-350562 NCBI chr 2:53,864,069...53,970,993
Ensembl chr 2:53,864,069...53,970,993
JBrowse link
G PSMF1 proteasome inhibitor subunit 1 TAS Reactome Reactome:R-HSA-350562 NCBI chr20:1,113,263...1,172,246
Ensembl chr20:1,113,240...1,189,415
JBrowse link
G SEM1 SEM1 26S proteasome complex subunit TAS Reactome Reactome:R-HSA-350562 NCBI chr 7:96,481,626...96,709,846
Ensembl chr 7:96,481,626...96,709,891
JBrowse link
regulation of cysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC7A11 solute carrier family 7 member 11 IEA Ensembl GO_REF:0000107 NCBI chr 4:138,164,097...138,242,349
Ensembl chr 4:138,164,097...138,242,349
JBrowse link
regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISS UniProtKB GO_REF:0000024 NCBI chr 1:154,567,778...154,584,708
Ensembl chr 1:154,567,778...154,580,013
JBrowse link
G DRD1 dopamine receptor D1 IEA Ensembl GO_REF:0000107 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G DRD4 dopamine receptor D4 ISS BHF-UCL GO_REF:0000024 NCBI chr11:637,269...640,706
Ensembl chr11:637,269...640,706
JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISS UniProtKB GO_REF:0000024 NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,960,356...63,962,507
Ensembl chr 5:63,960,356...63,962,507
JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 IEA Ensembl GO_REF:0000107 NCBI chr 2:156,324,432...156,332,724
Ensembl chr 2:156,324,437...156,342,348
JBrowse link
G PDE1B phosphodiesterase 1B IEA Ensembl GO_REF:0000107 NCBI chr12:54,549,601...54,579,239
Ensembl chr12:54,549,601...54,579,239
JBrowse link
G PNKD PNKD metallo-beta-lactamase domain containing IEA Ensembl GO_REF:0000107 NCBI chr 2:218,270,485...218,346,793
Ensembl chr 2:218,270,392...218,346,793
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase IMP (PMID:22314364) ParkinsonsUK-UCL PMID:22314364 NCBI chr 6:161,347,417...162,727,802
Ensembl chr 6:161,347,417...162,727,771
Ensembl chr 6:161,347,417...162,727,771
JBrowse link
G SLC6A3 solute carrier family 6 member 3 IEA Ensembl GO_REF:0000107 NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440
JBrowse link
G TACR3 tachykinin receptor 3 IEA Ensembl GO_REF:0000107 NCBI chr 4:103,586,031...103,719,985
Ensembl chr 4:103,586,031...103,719,985
JBrowse link
regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway ISO RGD PMID:19858196 RGD:6484536 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,498...112,846,239
JBrowse link
G SLC7A11 solute carrier family 7 member 11 IEA Ensembl GO_REF:0000107 NCBI chr 4:138,164,097...138,242,349
Ensembl chr 4:138,164,097...138,242,349
JBrowse link
regulation of glutamine family amino acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRT4 sirtuin 4 IEA Ensembl GO_REF:0000107 NCBI chr12:120,291,780...120,313,249
Ensembl chr12:120,302,316...120,313,249
JBrowse link
regulation of homocysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHMT betaine--homocysteine S-methyltransferase NAS (PMID:10075673) UniProtKB PMID:10075673 NCBI chr 5:79,111,809...79,132,288
Ensembl chr 5:79,111,809...79,132,288
JBrowse link
regulation of sulfur amino acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1A calcium voltage-gated channel subunit alpha1 A IEA Ensembl GO_REF:0000107 NCBI chr19:13,206,442...13,506,479
Ensembl chr19:13,206,442...13,633,025
JBrowse link
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 ISO RGD PMID:23098818 RGD:11353778 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,881
JBrowse link
spermidine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SAT1 spermidine/spermine N1-acetyltransferase 1 IBA
IDA
(PMID:21873635)
(PMID:15283699)
GO_Central
UniProt
PMID:15283699, PMID:21873635 NCBI chr  X:23,783,158...23,786,223
Ensembl chr  X:23,783,173...23,786,226
JBrowse link
G SAT2 spermidine/spermine N1-acetyltransferase family member 2 NOT IDA
IBA
(PMID:12803540)
(PMID:15283699)
(PMID:21873635)
UniProtKB
UniProt
GO_Central
PMID:12803540, PMID:15283699, PMID:21873635 NCBI chr17:7,626,234...7,627,878
Ensembl chr17:7,626,234...7,627,876
JBrowse link
spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGMAT agmatinase IEA UniProt GO_REF:0000043 NCBI chr 1:15,571,699...15,585,051
Ensembl chr 1:15,571,699...15,585,051
JBrowse link
G AMD1 adenosylmethionine decarboxylase 1 IEA
IBA
(PMID:21873635) InterPro
UniProt
GO_Central
PMID:21873635 GO_REF:0000002, GO_REF:0000043 NCBI chr 6:110,814,617...110,895,713
Ensembl chr 6:110,874,770...110,898,879
JBrowse link
G SRM spermidine synthase IDA
IBA
IEA
(PMID:17585781)
(PMID:21873635)
UniProtKB
GO_Central
PMID:17585781, PMID:21873635 GO_REF:0000041 NCBI chr 1:11,054,589...11,060,053
Ensembl chr 1:11,054,584...11,060,020
JBrowse link
spermidine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHPS deoxyhypusine synthase IEA Ensembl GO_REF:0000107 NCBI chr19:12,672,470...12,681,880
Ensembl chr19:12,675,717...12,681,880
JBrowse link
G PAOX polyamine oxidase IDA (PMID:16354669) UniProtKB PMID:16354669 NCBI chr10:133,379,262...133,391,694
Ensembl chr10:133,380,017...133,420,271
Ensembl chr10:133,380,017...133,420,271
JBrowse link
spermidine deacetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC10 histone deacetylase 10 IDA (PMID:28516954) UniProt PMID:28516954 NCBI chr22:50,245,183...50,251,265
Ensembl chr22:50,245,183...50,251,405
JBrowse link
G HDAC6 histone deacetylase 6 NOT IDA (PMID:28516954) UniProt PMID:28516954 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982
JBrowse link
spermidine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHPS deoxyhypusine synthase IDA (PMID:23525104) UniProtKB PMID:23525104 NCBI chr19:12,672,470...12,681,880
Ensembl chr19:12,675,717...12,681,880
JBrowse link
spermine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SAT2 spermidine/spermine N1-acetyltransferase family member 2 IDA (PMID:12803540) UniProtKB PMID:12803540 NCBI chr17:7,626,234...7,627,878
Ensembl chr17:7,626,234...7,627,876
JBrowse link
spermine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMD1 adenosylmethionine decarboxylase 1 IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 6:110,814,617...110,895,713
Ensembl chr 6:110,874,770...110,898,879
JBrowse link
G SMS spermine synthase IEA
IBA
(PMID:21873635) InterPro
GO_Central
UniProtKB
PMID:21873635 GO_REF:0000002, GO_REF:0000041 NCBI chr  X:21,940,709...21,994,837
Ensembl chr  X:21,940,709...21,994,837
JBrowse link
spermine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAOX polyamine oxidase IDA (PMID:16354669) UniProtKB PMID:16354669 NCBI chr10:133,379,262...133,391,694
Ensembl chr10:133,380,017...133,420,271
Ensembl chr10:133,380,017...133,420,271
JBrowse link
G SMOX spermine oxidase IEA
IDA
(PMID:18422650) UniProtKB PMID:18422650 GO_REF:0000041 NCBI chr20:4,148,828...4,187,732
Ensembl chr20:4,120,980...4,187,747
JBrowse link
spermine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMS spermine synthase ISO (MGI:MGI:1197776|PMID:9467015) MGI PMID:9467015 MGI:MGI:1197776 NCBI chr  X:21,940,709...21,994,837
Ensembl chr  X:21,940,709...21,994,837
JBrowse link
tryptophan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAT aminoadipate aminotransferase TAS Reactome Reactome:R-HSA-71240 NCBI chr 4:170,060,222...170,091,699
Ensembl chr 4:170,060,222...170,091,699
JBrowse link
G ACMSD aminocarboxymuconate semialdehyde decarboxylase TAS (PMID:12140278), (PMID:19843166) ParkinsonsUK-UCL PMID:12140278, PMID:19843166 NCBI chr 2:134,838,319...134,902,906
Ensembl chr 2:134,838,616...134,902,034
JBrowse link
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase TAS Reactome Reactome:R-HSA-71240 NCBI chr 2:42,767,087...42,801,002
Ensembl chr 2:42,767,089...42,792,593
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 TAS Reactome Reactome:R-HSA-71240 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790
JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 TAS Reactome Reactome:R-HSA-71240 NCBI chr 8:39,934,955...40,016,391
Ensembl chr 8:39,934,614...40,016,391
JBrowse link
G KMO kynurenine 3-monooxygenase TAS Reactome Reactome:R-HSA-71240 NCBI chr 1:241,531,883...241,595,642
Ensembl chr 1:241,532,134...241,595,642
JBrowse link
G KYAT1 kynurenine aminotransferase 1 TAS Reactome Reactome:R-HSA-71240 NCBI chr 9:128,832,942...128,882,523
Ensembl chr 9:128,819,663...128,881,931
Ensembl chr 9:128,819,663...128,881,931
JBrowse link
G KYNU kynureninase IEA
IMP
TAS
(PMID:17334708) InterPro
UniProtKB
Reactome
PMID:17334708 GO_REF:0000002, Reactome:R-HSA-71240 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase TAS Reactome Reactome:R-HSA-71240 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
JBrowse link
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KYNU kynureninase IEA Ensembl GO_REF:0000107 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFMID arylformamidase IEA
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr17:78,185,102...78,207,702
Ensembl chr17:78,187,317...78,207,701
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 IEA
IBA
(PMID:21873635) InterPro
GO_Central
UniProtKB
PMID:21873635 GO_REF:0000002, GO_REF:0000041 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790
JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 IEA
IBA
ISS
IDA
(PMID:21873635)
(PMID:17499941)
(PMID:17671174)
InterPro
GO_Central
UniProtKB
PMID:17499941, PMID:17671174, PMID:21873635 GO_REF:0000002, GO_REF:0000041 NCBI chr 8:39,934,955...40,016,391
Ensembl chr 8:39,934,614...40,016,391
JBrowse link
G KYNU kynureninase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase IEA
IDA
(PMID:27762317) InterPro
UniProtKB
PMID:27762317 GO_REF:0000002, GO_REF:0000041 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
JBrowse link
tryptophan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISS UniProtKB GO_REF:0000024 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,656...78,050,395
JBrowse link
G GCDH glutaryl-CoA dehydrogenase IEA UniProtKB GO_REF:0000041 NCBI chr19:12,891,129...12,899,999
Ensembl chr19:12,891,160...12,914,207
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase ISO RGD PMID:3400092, PMID:3899109, PMID:10719243 RGD:2290190, RGD:2290313, RGD:2291804 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18650
    metabolic process 12284
      organic substance metabolic process 11720
        organonitrogen compound metabolic process 7147
          amine metabolic process 154
            2-aminobenzenesulfonate metabolic process + 0
            amine biosynthetic process + 26
            amine catabolic process + 23
            cellular amine metabolic process + 146
            cytokinin metabolic process + 0
            methane biosynthetic process from dimethylamine + 0
            methane biosynthetic process from trimethylamine + 0
            methylamine metabolic process + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.