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ONTOLOGY REPORT - ANNOTATIONS


Term:cobalamin metabolic process
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Accession:GO:0009235 term browser browse the term
Definition:The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
Synonyms:exact_synonym: cobalamin metabolism;   vitamin B12 metabolic process;   vitamin B12 metabolism
 narrow_synonym: vitamin B12 reduction



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cobalamin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 involved_in ISO
IEA
MGI:2155908 (MGI:4436975|PMID:19897579)
GO_REF:0000107
RGD
Ensembl
PMID:19897579 GO_REF:0000107 MGI:4436975 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcd4 ATP binding cassette subfamily D member 4 involved_in ISO (PMID:22922874) RGD PMID:22922874 NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276
JBrowse link
G Amn amnion associated transmembrane protein involved_in ISO (PMID:14576052) RGD PMID:14576052 NCBI chr 6:130,311,372...130,318,815
Ensembl chr 6:130,311,372...130,318,815
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase TAS RGD PMID:3994693 RGD:5135263 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
JBrowse link
G Cblif cobalamin binding intrinsic factor involved_in IDA
IEA
ISO
GO_REF:0000107
MGI:4363945 (MGI:5586607|PMID:24911144)
Ensembl
RGD
PMID:24911144 PMID:14166172 GO_REF:0000107 MGI:5586607, RGD:1624368 NCBI chr 1:208,605,983...208,620,231
Ensembl chr 1:208,605,983...208,620,344
JBrowse link
G Cd320 CD320 molecule involved_in ISO MGI:3858540 (MGI:5506682|PMID:23430977) RGD PMID:23430977 MGI:5506682 NCBI chr 7:14,626,171...14,631,976
Ensembl chr 7:14,609,146...14,631,976
JBrowse link
G Cubn cubilin involved_in ISO (PMID:14576052) RGD PMID:14576052 NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231
JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase TAS RGD PMID:3994693 RGD:5135263 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125
JBrowse link
G Lmbrd1 LMBR1 domain containing 1 involved_in ISO (PMID:27456980) RGD PMID:27456980 NCBI chr 9:27,096,387...27,178,095
Ensembl chr 9:27,096,297...27,178,090
JBrowse link
G Mmaa metabolism of cobalamin associated A involved_in ISO (PMID:31056463) RGD PMID:31056463 NCBI chr19:28,619,060...28,649,319
Ensembl chr19:28,619,087...28,649,319
JBrowse link
G Mmachc metabolism of cobalamin associated C involved_in ISO
IBA
(PMID:19700356), (PMID:22642810), (PMID:23825108)
PMID:21873635
RGD PMID:19700356 PMID:22642810 PMID:23825108 PMID:21873635 RGD:13792537 NCBI chr 5:130,166,056...130,172,735
Ensembl chr 5:130,166,451...130,172,601
JBrowse link
G Mmadhc metabolism of cobalamin associated D involved_in IEA
ISS
ISO
GO_REF:0000002
GO_REF:0000024
(PMID:24722857)
InterPro
UniProt
RGD
PMID:24722857 GO_REF:0000002 GO_REF:0000024 NCBI chr 3:34,708,649...34,726,554
Ensembl chr 3:34,708,649...34,726,771
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in ISO
IEA
(PMID:23825108)
MGI:2180496 (MGI:1930456|PMID:11158293)
GO_REF:0000107
RGD
Ensembl
PMID:11158293 PMID:23825108 GO_REF:0000107 MGI:1930456 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (MGI:3710265|PMID:17369066) RGD PMID:17369066 MGI:3710265 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425
JBrowse link
cobalamin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cubn cubilin IMP RGD PMID:14576052 RGD:8554807 NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231
JBrowse link
positive regulation of cobalamin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clybl citramalyl-CoA lyase involved_in ISO (MGI:5926841|PMID:29056341) RGD PMID:29056341 MGI:5926841 NCBI chr15:99,283,644...99,505,697
Ensembl chr15:99,283,650...99,505,695
JBrowse link
regulation of cobalamin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clybl citramalyl-CoA lyase involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:29056341)
PMID:21873635
(MGI:5926841|PMID:29056341)
UniProt
RGD
PMID:29056341 PMID:21873635 GO_REF:0000024 MGI:5926841, RGD:13792537 NCBI chr15:99,283,644...99,505,697
Ensembl chr15:99,283,650...99,505,695
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    metabolic process 12042
      small molecule metabolic process 1829
        vitamin metabolic process 93
          water-soluble vitamin metabolic process 45
            cobalamin metabolic process 15
              cobalamin biosynthetic process + 0
              cobalamin catabolic process 1
              negative regulation of cobalamin metabolic process 0
              positive regulation of cobalamin metabolic process 1
              regulation of cobalamin metabolic process + 1
paths to the root