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ONTOLOGY REPORT - ANNOTATIONS


Term:thiamine diphosphate biosynthetic process
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Accession:GO:0009229 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.
Synonyms:exact_synonym: TPP biosynthesis;   TPP biosynthetic process;   thiamin diphosphate biosynthetic process;   thiamin pyrophosphate biosynthesis;   thiamin pyrophosphate biosynthetic process;   thiamine diphosphate anabolism;   thiamine diphosphate biosynthesis;   thiamine diphosphate formation;   thiamine diphosphate synthesis;   thiamine pyrophosphate biosynthesis;   thiamine pyrophosphate biosynthetic process


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thiamine diphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc19a2 solute carrier family 19 member 2 involved_in ISO (PMID:8186267) MGI PMID:8186267 NCBI chrNW_004955462:7,786,920...7,804,828
Ensembl chrNW_004955462:7,786,913...7,805,792
JBrowse link
G Slc19a3 solute carrier family 19 member 3 involved_in ISO (PMID:28665968)
(PMID:8186267)
MGI PMID:8186267 PMID:28665968 NCBI chrNW_004955453:6,935,372...6,957,808
Ensembl chrNW_004955453:6,935,371...6,958,103
JBrowse link
G Slc25a19 solute carrier family 25 member 19 involved_in ISO (PMID:17035501), (PMID:8186267) MGI PMID:8186267 PMID:17035501 NCBI chrNW_004955553:2,134,715...2,160,777 JBrowse link
G Thtpa thiamine triphosphatase involved_in ISO (PMID:18276586) MGI PMID:18276586 NCBI chrNW_004955409:36,803,721...36,808,094
Ensembl chrNW_004955409:36,804,258...36,808,091
JBrowse link
G Tpk1 thiamin pyrophosphokinase 1 involved_in ISO (PMID:10567383)
(PMID:11342111), (PMID:38547260)
(PMID:38547260)
MGI
UniProt
PMID:10567383 PMID:11342111 PMID:38547260 NCBI chrNW_004955491:621,941...968,570
Ensembl chrNW_004955491:623,530...968,253
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12533
    cellular process 11968
      metabolic process 7959
        biosynthetic process 5495
          organophosphate biosynthetic process 400
            thiamine diphosphate biosynthetic process 5
              negative regulation of thiamine diphosphate biosynthetic process 0
              regulation of thiamine diphosphate biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 12533
    cellular process 11968
      metabolic process 7959
        biosynthetic process 5495
          small molecule biosynthetic process 461
            vitamin biosynthetic process 20
              water-soluble vitamin biosynthetic process 9
                thiamine-containing compound biosynthetic process 5
                  thiamine diphosphate biosynthetic process 5
                    negative regulation of thiamine diphosphate biosynthetic process 0
                    regulation of thiamine diphosphate biosynthetic process + 0
paths to the root