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ONTOLOGY REPORT - ANNOTATIONS

Term:pyrimidine deoxyribonucleotide catabolic process
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Accession:GO:0009223 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
Synonyms:exact_synonym: pyrimidine deoxyribonucleotide breakdown;   pyrimidine deoxyribonucleotide catabolism;   pyrimidine deoxyribonucleotide degradation


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pyrimidine deoxyribonucleotide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NT5C 5', 3'-nucleotidase, cytosolic involved_in IDA
IBA		 (PMID:10681516) UniProt
GO_Central		 PMID:10681516 GO_REF:0000033 NCBI chr17:75,130,228...75,131,742
Ensembl chr17:75,130,225...75,131,757 		JBrowse link
G NT5M 5',3'-nucleotidase, mitochondrial involved_in TAS
IBA		 (PMID:10899995) PINC
GO_Central		 PMID:10899995 GO_REF:0000033 NCBI chr17:17,303,373...17,347,663
Ensembl chr17:17,303,335...17,347,663 		JBrowse link
dCMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPYD dihydropyrimidine dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000 		JBrowse link
G DPYS dihydropyrimidinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:104,379,431...104,467,055
Ensembl chr 8:104,330,324...104,467,055 		JBrowse link
G NT5C 5', 3'-nucleotidase, cytosolic involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:75,130,228...75,131,742
Ensembl chr17:75,130,225...75,131,757 		JBrowse link
G UPB1 beta-ureidopropionase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:24,495,332...24,528,390
Ensembl chr22:24,494,107...24,528,390 		JBrowse link
G UPP1 uridine phosphorylase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:48,088,704...48,108,736
Ensembl chr 7:48,088,628...48,108,736 		JBrowse link
G UPP2 uridine phosphorylase 2 involved_in IDA (PMID:12849978) MGI PMID:12849978 NCBI chr 2:157,995,179...158,136,154
Ensembl chr 2:157,876,679...158,136,154 		JBrowse link
dCTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCTPP1 dCTP pyrophosphatase 1 involved_in IMP
IBA		 (PMID:24467396) UniProt
GO_Central		 PMID:24467396 GO_REF:0000033 NCBI chr16:30,423,615...30,430,030
Ensembl chr16:30,423,615...30,430,030 		JBrowse link
depyrimidination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MBD4 methyl-CpG binding domain 4, DNA glycosylase involved_in TAS Reactome Reactome:R-HSA-110329 NCBI chr 3:129,430,947...129,439,948
Ensembl chr 3:129,430,947...129,440,179 		JBrowse link
G NEIL1 nei like DNA glycosylase 1 involved_in TAS Reactome Reactome:R-HSA-110329 NCBI chr15:75,347,039...75,357,115
Ensembl chr15:75,346,955...75,357,115 		JBrowse link
G NEIL2 nei like DNA glycosylase 2 involved_in TAS Reactome Reactome:R-HSA-110329 NCBI chr 8:11,769,710...11,787,345
Ensembl chr 8:11,769,639...11,787,345 		JBrowse link
G NTHL1 nth like DNA glycosylase 1 involved_in TAS Reactome Reactome:R-HSA-110329 NCBI chr16:2,039,820...2,047,834
Ensembl chr16:2,039,815...2,047,866 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase involved_in TAS Reactome Reactome:R-HSA-110329 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 involved_in TAS Reactome Reactome:R-HSA-110329 NCBI chr12:54,158,235...54,188,985
Ensembl chr12:54,121,277...54,189,008 		JBrowse link
G TDG thymine DNA glycosylase involved_in TAS Reactome Reactome:R-HSA-110329 NCBI chr12:103,965,872...103,988,874
Ensembl chr12:103,965,822...103,988,874 		JBrowse link
G UNG uracil DNA glycosylase involved_in TAS Reactome Reactome:R-HSA-110329 NCBI chr12:109,097,597...109,110,992
Ensembl chr12:109,097,597...109,126,725 		JBrowse link
dTMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NT5C 5', 3'-nucleotidase, cytosolic involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:75,130,228...75,131,742
Ensembl chr17:75,130,225...75,131,757 		JBrowse link
G TYMP thymidine phosphorylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032 		JBrowse link
G UPP1 uridine phosphorylase 1 involved_in
NOT|involved_in		 IEA
ISO		 (PMID:15772079) Ensembl
UniProt		 PMID:15772079 GO_REF:0000107 NCBI chr 7:48,088,704...48,108,736
Ensembl chr 7:48,088,628...48,108,736 		JBrowse link
dTTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCTPP1 dCTP pyrophosphatase 1 NOT|involved_in IMP (PMID:24467396) UniProt PMID:24467396 NCBI chr16:30,423,615...30,430,030
Ensembl chr16:30,423,615...30,430,030 		JBrowse link
dUMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPYD dihydropyrimidine dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000 		JBrowse link
G DPYS dihydropyrimidinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:104,379,431...104,467,055
Ensembl chr 8:104,330,324...104,467,055 		JBrowse link
G NT5C 5', 3'-nucleotidase, cytosolic involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:75,130,228...75,131,742
Ensembl chr17:75,130,225...75,131,757 		JBrowse link
G NT5M 5',3'-nucleotidase, mitochondrial involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12234672) Ensembl
MGI		 PMID:12234672 GO_REF:0000107 NCBI chr17:17,303,373...17,347,663
Ensembl chr17:17,303,335...17,347,663 		JBrowse link
G UPB1 beta-ureidopropionase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:24,495,332...24,528,390
Ensembl chr22:24,494,107...24,528,390 		JBrowse link
G UPP1 uridine phosphorylase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:48,088,704...48,108,736
Ensembl chr 7:48,088,628...48,108,736 		JBrowse link
dUTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUT deoxyuridine triphosphatase involved_in ISO
IEA
IBA		 RGD
InterPro
UniProt
GO_Central		 PMID:1315924 PMID:3032103 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 RGD:2300191 RGD:2301218 NCBI chr15:48,331,095...48,343,373
Ensembl chr15:48,331,011...48,343,373 		JBrowse link
G LINC03106 long intergenic non-protein coding RNA 3106 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:26,066,675...26,118,408
Ensembl chr 9:26,066,675...26,118,408 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19688
    cellular process 18940
      metabolic process 12898
        catabolic process 3025
          carbohydrate derivative catabolic process 290
            deoxyribose phosphate catabolic process 34
              pyrimidine deoxyribonucleotide catabolic process 19
                dCDP catabolic process 0
                dCMP catabolic process 6
                dCTP catabolic process 1
                dTDP catabolic process 0
                dTMP catabolic process 3
                dTTP catabolic process 1
                dUDP catabolic process 0
                dUMP catabolic process 6
                dUTP catabolic process 2
                depyrimidination 8
Path 2
Term Annotations click to browse term
  biological_process 19688
    cellular process 18940
      metabolic process 12898
        primary metabolic process 11216
          nucleobase-containing compound metabolic process 6781
            nucleobase-containing small molecule metabolic process 755
              nucleoside phosphate metabolic process 721
                nucleotide metabolic process 564
                  deoxyribonucleotide metabolic process 52
                    2'-deoxyribonucleotide metabolic process 50
                      pyrimidine deoxyribonucleotide metabolic process 25
                        pyrimidine deoxyribonucleotide catabolic process 19
                          dCDP catabolic process 0
                          dCMP catabolic process 6
                          dCTP catabolic process 1
                          dTDP catabolic process 0
                          dTMP catabolic process 3
                          dTTP catabolic process 1
                          dUDP catabolic process 0
                          dUMP catabolic process 6
                          dUTP catabolic process 2
                          depyrimidination 8
paths to the root