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ONTOLOGY REPORT - ANNOTATIONS

Term:cyclic nucleotide metabolic process
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Accession:GO:0009187 term browser browse the term
Definition:The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.
Synonyms:exact_synonym: cyclic nucleotide metabolism


show annotations for term's descendants           Sort by:
cAMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy1 adenylate cyclase 1 involved_in ISO
IBA		 RGD
GO_Central
MGI		 PMID:14985420 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:2312640 NCBI chr11:7,013,433...7,128,506
Ensembl chr11:7,013,489...7,128,506 		JBrowse link
G Adcy10 adenylate cyclase 10 involved_in ISO RGD
MGI		 PMID:7225326 PMID:9874775 PMID:16627466 PMID:16964251 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:1299450 RGD:2313171 RGD:2313173 RGD:2313177 NCBI chr 1:165,309,114...165,404,347
Ensembl chr 1:165,312,752...165,404,343 		JBrowse link
G Adcy2 adenylate cyclase 2 involved_in ISO
IBA		 RGD
GO_Central
MGI		 PMID:11738086 PMID:12711600 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:2312641 RGD:2312674 NCBI chr13:68,768,162...69,147,719
Ensembl chr13:68,768,162...69,147,660 		JBrowse link
G Adcy3 adenylate cyclase 3 involved_in IMP
IBA
ISO		 (MGI:1889935|PMID:11055432) UniProt
GO_Central
MGI
RGD		 PMID:11055432 PMID:12711600 GO_REF:0000033 GO_REF:0000096 MGI:1889935 MGI:4417868 RGD:2312674 NCBI chr12:4,183,397...4,263,525
Ensembl chr12:4,183,103...4,263,525 		JBrowse link
G Adcy4 adenylate cyclase 4 involved_in
acts_upstream_of_or_within		 ISO
IBA
TAS		 (PMID:7766992) RGD
GO_Central
MGI		 PMID:7766992 PMID:11738086 PMID:12711600 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:2312641 RGD:2312674 NCBI chr14:56,006,513...56,021,552
Ensembl chr14:56,006,514...56,021,552 		JBrowse link
G Adcy5 adenylate cyclase 5 involved_in
acts_upstream_of_or_within		 ISO
IBA
TAS		 (PMID:7766992) RGD
GO_Central
MGI		 PMID:7766992 PMID:10894801 PMID:11738086 PMID:12711600 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:2312641 RGD:2312674 RGD:2315006 NCBI chr16:34,974,933...35,126,108
Ensembl chr16:34,975,247...35,126,108 		JBrowse link
G Adcy6 adenylate cyclase 6 involved_in IMP
IBA
ISO		 (MGI:4457984|PMID:20466003) UniProt
GO_Central
MGI
RGD		 PMID:10866989 PMID:10894801 PMID:11738086 PMID:12711600 PMID:15579502 More... GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4457984 MGI:4834177 RGD:1598749 RGD:2312641 RGD:2312654 RGD:2312674 RGD:2312678 RGD:2313211 RGD:2315006 NCBI chr15:98,484,982...98,508,119
Ensembl chr15:98,487,854...98,507,957 		JBrowse link
G Adcy7 adenylate cyclase 7 acts_upstream_of_or_within
involved_in		 ISO
TAS
IBA		 (PMID:7961850) RGD
MGI
GO_Central		 PMID:7961850 PMID:12711600 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:2312674 NCBI chr 8:88,998,818...89,056,593
Ensembl chr 8:88,999,031...89,056,590 		JBrowse link
G Adcy8 adenylate cyclase 8 involved_in ISO
IBA		 RGD
GO_Central
MGI		 PMID:16741924 PMID:19305019 PMID:19444869 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:2312769 RGD:2312785 RGD:7241269 NCBI chr15:64,570,884...64,794,145
Ensembl chr15:64,568,933...64,794,145 		JBrowse link
G Adcy9 adenylate cyclase 9 acts_upstream_of_or_within
involved_in		 ISO
IDA		 (PMID:7575502), (PMID:8662814) RGD
MGI		 PMID:7575502 PMID:8662814 PMID:19444869 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:2312785 NCBI chr16:4,102,750...4,255,094
Ensembl chr16:4,105,393...4,238,362 		JBrowse link
G Pth2 parathyroid hormone 2 acts_upstream_of_or_within TAS (PMID:11818570) MGI PMID:11818570 NCBI chr 7:44,829,447...44,831,262
Ensembl chr 7:44,830,419...44,831,262 		JBrowse link
cAMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde4a phosphodiesterase 4A, cAMP specific involved_in IDA
ISO		 (MGI:1927461|PMID:11267656) UniProt
MGI		 PMID:11267656 GO_REF:0000096 GO_REF:0000119 MGI:1927461 MGI:4417868 MGI:4834177 NCBI chr 9:21,076,998...21,124,544
Ensembl chr 9:21,077,010...21,124,544 		JBrowse link
cAMP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacnb4 calcium channel, voltage-dependent, beta 4 subunit acts_upstream_of_or_within IMP (PMID:7595494) MGI PMID:7595494 NCBI chr 2:52,318,332...52,566,816
Ensembl chr 2:52,318,337...52,566,843 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:141,028,532...141,056,695
Ensembl chr 4:141,028,551...141,056,695 		JBrowse link
G Hrh3 histamine receptor H3 involved_in ISO RGD
MGI		 PMID:11130725 GO_REF:0000096 MGI:4417868 RGD:151708734 NCBI chr 2:179,741,258...179,746,264
Ensembl chr 2:179,741,258...179,746,281 		JBrowse link
cGMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gucy1a1 guanylate cyclase 1, soluble, alpha 1 involved_in
acts_upstream_of_or_within		 ISO
IMP
IBA		 (PMID:16614755) MGI
GO_Central		 PMID:16614755 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 3:81,999,734...82,053,253
Ensembl chr 3:81,999,734...82,053,096 		JBrowse link
G Gucy1b1 guanylate cyclase 1, soluble, beta 1 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 3:81,939,311...81,982,018
Ensembl chr 3:81,939,313...81,981,996 		JBrowse link
G Gucy2c guanylate cyclase 2c involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:136,674,282...136,758,740
Ensembl chr 6:136,674,282...136,758,763 		JBrowse link
G Gucy2d guanylate cyclase 2d involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000096 MGI:4417868 NCBI chr 7:98,089,623...98,126,685
Ensembl chr 7:98,089,623...98,126,686 		JBrowse link
G Gucy2e guanylate cyclase 2e involved_in IDA
IBA		 (MGI:5049799|PMID:21598940) UniProt
GO_Central		 PMID:21598940 GO_REF:0000033 MGI:5049799 NCBI chr11:69,108,943...69,128,083
Ensembl chr11:69,108,943...69,127,862 		JBrowse link
G Gucy2f guanylate cyclase 2f involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:140,862,282...140,980,399
Ensembl chr  X:140,864,156...140,979,927 		JBrowse link
G Gucy2g guanylate cyclase 2g acts_upstream_of_or_within
involved_in		 ISS
IBA		 (MGI:1194478|PMID:9422765) GOC
GO_Central		 PMID:9422765 GO_REF:0000033 MGI:1194478 NCBI chr19:55,186,531...55,229,684
Ensembl chr19:55,186,531...55,229,668 		JBrowse link
G Nppa natriuretic peptide type A involved_in
acts_upstream_of		 ISO
IBA		 RGD
GO_Central
MGI		 PMID:10559136 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:619660 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536 		JBrowse link
G Nppb natriuretic peptide type B acts_upstream_of
involved_in		 ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662 		JBrowse link
G Nppc natriuretic peptide type C acts_upstream_of
involved_in		 IMP
IBA
ISO		 (MGI:2177134|PMID:11259675) GO_Central
MGI		 PMID:11259675 GO_REF:0000033 GO_REF:0000119 MGI:2177134 MGI:4834177 NCBI chr 1:86,594,015...86,598,295
Ensembl chr 1:86,594,013...86,598,293 		JBrowse link
G Npr1 natriuretic peptide receptor 1 involved_in
acts_upstream_of_or_within		 ISO
IBA
IMP		 (MGI:2179542|PMID:11997476) MGI
GO_Central
GOC		 PMID:11997476 GO_REF:0000033 GO_REF:0000119 MGI:2179542 MGI:4834177 NCBI chr 3:90,357,898...90,373,235
Ensembl chr 3:90,357,898...90,373,173 		JBrowse link
G Npr2 natriuretic peptide receptor 2 acts_upstream_of
involved_in
acts_upstream_of_or_within		 ISO
IBA
IDA		 (MGI:2682104|PMID:14514678) MGI
GO_Central
GOC		 PMID:14514678 GO_REF:0000033 GO_REF:0000119 MGI:2682104 MGI:4834177 NCBI chr 4:43,629,015...43,651,437
Ensembl chr 4:43,631,935...43,651,244 		JBrowse link
cGMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde1a phosphodiesterase 1A, calmodulin-dependent involved_in ISO RGD
MGI		 PMID:16514069 GO_REF:0000096 MGI:4417868 RGD:2312521 NCBI chr 2:79,664,797...80,026,862
Ensembl chr 2:79,664,797...79,959,802 		JBrowse link
G Pde2a phosphodiesterase 2A, cGMP-stimulated involved_in IMP
IBA
ISO		 (MGI:4420377|PMID:19632989) UniProt
GO_Central
MGI		 PMID:19632989 GO_REF:0000033 GO_REF:0000119 MGI:4420377 MGI:4834177 NCBI chr 7:101,070,905...101,162,026
Ensembl chr 7:101,060,093...101,162,026
Ensembl chr 7:101,060,093...101,162,026 		JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific acts_upstream_of_or_within IDA (PMID:12554648) MGI PMID:12554648 NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023 		JBrowse link
G Pde9a phosphodiesterase 9A involved_in IDA
IMP
ISO
IBA		 (MGI:1266874|PMID:9624145)
(MGI:5634842|PMID:25799991)		 UniProt
MGI
GO_Central		 PMID:9624145 PMID:25799991 GO_REF:0000033 GO_REF:0000119 MGI:1266874 MGI:4834177 MGI:5634842 NCBI chr17:31,605,079...31,695,284
Ensembl chr17:31,605,184...31,695,284 		JBrowse link
cGMP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 acts_upstream_of_or_within IMP (PMID:3038581), (PMID:7518067) MGI PMID:3038581 PMID:7518067 NCBI chr 6:113,720,803...114,019,574
Ensembl chr 6:113,720,792...114,019,574 		JBrowse link
G Npr2 natriuretic peptide receptor 2 involved_in IMP (PMID:15722353) MGI PMID:15722353 NCBI chr 4:43,629,015...43,651,437
Ensembl chr 4:43,631,935...43,651,244 		JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific acts_upstream_of_or_within IMP (PMID:19474061), (PMID:20511540) MGI PMID:19474061 PMID:20511540 NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023 		JBrowse link
G Pde9a phosphodiesterase 9A involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:31,605,079...31,695,284
Ensembl chr17:31,605,184...31,695,284 		JBrowse link
G Rora RAR-related orphan receptor alpha acts_upstream_of_or_within IMP (PMID:7518067) MGI PMID:7518067 NCBI chr 9:68,560,627...69,295,528
Ensembl chr 9:68,561,068...69,295,528 		JBrowse link
cyclic nucleotide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy1 adenylate cyclase 1 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr11:7,013,433...7,128,506
Ensembl chr11:7,013,489...7,128,506 		JBrowse link
G Adcy10 adenylate cyclase 10 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 1:165,309,114...165,404,347
Ensembl chr 1:165,312,752...165,404,343 		JBrowse link
G Adcy2 adenylate cyclase 2 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr13:68,768,162...69,147,719
Ensembl chr13:68,768,162...69,147,660 		JBrowse link
G Adcy3 adenylate cyclase 3 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr12:4,183,397...4,263,525
Ensembl chr12:4,183,103...4,263,525 		JBrowse link
G Adcy4 adenylate cyclase 4 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr14:56,006,513...56,021,552
Ensembl chr14:56,006,514...56,021,552 		JBrowse link
G Adcy5 adenylate cyclase 5 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr16:34,974,933...35,126,108
Ensembl chr16:34,975,247...35,126,108 		JBrowse link
G Adcy6 adenylate cyclase 6 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr15:98,484,982...98,508,119
Ensembl chr15:98,487,854...98,507,957 		JBrowse link
G Adcy7 adenylate cyclase 7 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 8:88,998,818...89,056,593
Ensembl chr 8:88,999,031...89,056,590 		JBrowse link
G Adcy8 adenylate cyclase 8 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr15:64,570,884...64,794,145
Ensembl chr15:64,568,933...64,794,145 		JBrowse link
G Adcy9 adenylate cyclase 9 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr16:4,102,750...4,255,094
Ensembl chr16:4,105,393...4,238,362 		JBrowse link
G Gucy1a1 guanylate cyclase 1, soluble, alpha 1 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 3:81,999,734...82,053,253
Ensembl chr 3:81,999,734...82,053,096 		JBrowse link
G Gucy1b1 guanylate cyclase 1, soluble, beta 1 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 3:81,939,311...81,982,018
Ensembl chr 3:81,939,313...81,981,996 		JBrowse link
G Gucy2c guanylate cyclase 2c involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 6:136,674,282...136,758,740
Ensembl chr 6:136,674,282...136,758,763 		JBrowse link
G Gucy2d guanylate cyclase 2d involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 7:98,089,623...98,126,685
Ensembl chr 7:98,089,623...98,126,686 		JBrowse link
G Gucy2e guanylate cyclase 2e involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr11:69,108,943...69,128,083
Ensembl chr11:69,108,943...69,127,862 		JBrowse link
G Gucy2f guanylate cyclase 2f involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr  X:140,862,282...140,980,399
Ensembl chr  X:140,864,156...140,979,927 		JBrowse link
G Gucy2g guanylate cyclase 2g involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr19:55,186,531...55,229,684
Ensembl chr19:55,186,531...55,229,668 		JBrowse link
G Npr1 natriuretic peptide receptor 1 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 3:90,357,898...90,373,235
Ensembl chr 3:90,357,898...90,373,173 		JBrowse link
G Npr2 natriuretic peptide receptor 2 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 4:43,629,015...43,651,437
Ensembl chr 4:43,631,935...43,651,244 		JBrowse link
cyclic nucleotide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr11:100,465,765...100,472,565
Ensembl chr11:100,465,730...100,482,555 		JBrowse link
cyclic purine nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ampd2 adenosine monophosphate deaminase 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:107,981,375...107,993,982
Ensembl chr 3:107,981,378...107,993,967 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    metabolic process 10995
      organic substance metabolic process 10563
        organophosphate metabolic process 1026
          nucleoside phosphate metabolic process 607
            nucleotide metabolic process 599
              cyclic nucleotide metabolic process 35
                cyclic nucleotide biosynthetic process + 23
                cyclic nucleotide catabolic process + 6
                cyclic purine nucleotide metabolic process + 34
Path 2
Term Annotations click to browse term
  biological_process 28573
    cellular process 17593
      cellular metabolic process 9652
        cellular aromatic compound metabolic process 5629
          nucleobase-containing compound metabolic process 5383
            nucleobase-containing small molecule metabolic process 666
              nucleoside phosphate metabolic process 607
                nucleotide metabolic process 599
                  cyclic nucleotide metabolic process 35
                    cyclic nucleotide biosynthetic process + 23
                    cyclic nucleotide catabolic process + 6
                    cyclic purine nucleotide metabolic process + 34
paths to the root