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ONTOLOGY REPORT - ANNOTATIONS


Term:purine nucleobase biosynthetic process
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Accession:GO:0009113 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
Synonyms:exact_synonym: purine base anabolism;   purine base biosynthesis;   purine base biosynthetic process;   purine base formation;   purine base synthesis
 xref: MetaCyc:PWY-841


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purine nucleobase biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppat phosphoribosyl pyrophosphate amidotransferase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:33,580,541...33,614,919
Ensembl chr14:33,580,541...33,614,919
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in ISO
IBA
(PMID:11516159)
PMID:21873635
RGD PMID:11516159, PMID:21873635 RGD:13792537 NCBI chr10:47,030,813...47,059,216
Ensembl chr10:47,031,050...47,059,216
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815
JBrowse link
adenine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:31,780,477...31,805,728
Ensembl chr11:31,780,487...31,805,728
JBrowse link
adenine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aprt adenine phosphoribosyl transferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:55,387,288...55,389,256
Ensembl chr19:55,387,288...55,389,256
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
guanine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in ISO
IBA
ISS
(PMID:19527031)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:19527031, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Prtfdc1 phosphoribosyl transferase domain containing 1 NOT|involved_in ISO (PMID:21054786) RGD PMID:21054786 NCBI chr17:87,926,242...88,037,040
Ensembl chr17:87,927,058...88,037,040
JBrowse link
hypoxanthine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO MGI:1857117|MGI:2683027 (MGI:3640719|PMID:10720488) RGD PMID:10720488 MGI:3640719 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 involved_in ISO (PMID:17701896) RGD PMID:17701896 NCBI chr  X:111,798,233...111,820,270
Ensembl chr  X:111,798,233...111,820,266
JBrowse link
hypoxanthine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in ISO
ISS
(PMID:19527031)
GO_REF:0000024
RGD
UniProt
PMID:19527031 GO_REF:0000024 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
xanthine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO MGI:1857117|MGI:2683027 (MGI:3640719|PMID:10720488) RGD PMID:10720488 MGI:3640719 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    metabolic process 11797
      pigment metabolic process 73
        pigment biosynthetic process 57
          purine nucleobase biosynthetic process 9
            adenine biosynthetic process + 3
            guanine biosynthetic process + 2
            hypoxanthine biosynthetic process + 3
            purine nucleobase salvage + 4
            xanthine biosynthetic process 1
Path 2
Term Annotations click to browse term
  biological_process 19491
    metabolic process 11797
      cellular metabolic process 10755
        cellular aromatic compound metabolic process 5636
          nucleobase-containing compound metabolic process 5420
            nucleobase-containing small molecule metabolic process 577
              nucleobase metabolic process 45
                purine nucleobase metabolic process 23
                  purine nucleobase biosynthetic process 9
                    adenine biosynthetic process + 3
                    guanine biosynthetic process + 2
                    hypoxanthine biosynthetic process + 3
                    purine nucleobase salvage + 4
                    xanthine biosynthetic process 1
paths to the root