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ONTOLOGY REPORT - ANNOTATIONS


Term:homoserine metabolic process
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Accession:GO:0009092 term browser browse the term
Definition:The chemical reactions and pathways involving homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine.
Synonyms:exact_synonym: homoserine metabolism


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transsulfuration term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:16636197, PMID:21873635 RGD:1600624, RGD:13792537 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Cth cystathionine gamma-lyase TAS
IBA
IEA
ISO
PMID:21873635
GO_REF:0000002
(PMID:19428278)
InterPro
RGD
PMID:19428278, PMID:15347670, PMID:21873635 GO_REF:0000002, RGD:1600762, RGD:13792537 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G LOC103691744 cystathionine gamma-lyase IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:264,747,068...264,765,112
Ensembl chr 2:264,746,485...264,765,085
JBrowse link
G Mpst mercaptopyruvate sulfurtransferase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:17130129, PMID:21873635 RGD:9685559, RGD:13792537 NCBI chr 7:119,626,636...119,631,317
Ensembl chr 7:119,626,637...119,631,425
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO (MGI:5621260|PMID:23190757) RGD PMID:23190757 MGI:5621260 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Tst thiosulfate sulfurtransferase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:119,616,323...119,623,072
Ensembl chr 7:119,616,324...119,623,072
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      primary metabolic process 10900
        cellular amino acid metabolic process 268
          alpha-amino acid metabolic process 190
            serine family amino acid metabolic process 40
              homoserine metabolic process 6
                L-methionine biosynthetic process from L-homoserine via cystathionine + 0
                homoserine biosynthetic process + 0
                homoserine catabolic process 0
                transsulfuration 6
Path 2
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      cellular metabolic process 11073
        organic acid metabolic process 1008
          oxoacid metabolic process 970
            carboxylic acid metabolic process 951
              cellular amino acid metabolic process 268
                alpha-amino acid metabolic process 190
                  serine family amino acid metabolic process 40
                    homoserine metabolic process 6
                      L-methionine biosynthetic process from L-homoserine via cystathionine + 0
                      homoserine biosynthetic process + 0
                      homoserine catabolic process 0
                      transsulfuration 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.