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ONTOLOGY REPORT - ANNOTATIONS


Term:methionine biosynthetic process
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Accession:GO:0009086 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
Synonyms:exact_synonym: methionine anabolism;   methionine biosynthesis;   methionine formation;   methionine synthesis



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methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADI1 acireductone dioxygenase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr2A:3,509,162...3,538,064
Ensembl chr2A:3,430,158...3,458,248
JBrowse link
G APIP APAF1 interacting protein involved_in IEA UniProt GO_REF:0000043 NCBI chr11:34,855,437...34,889,486
Ensembl chr11:34,730,671...34,764,732
JBrowse link
G BHMT betaine--homocysteine S-methyltransferase involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:3510291|PMID:15217352) RGD
InterPro
UniProt
MGI
PMID:15217352 PMID:15845641 GO_REF:0000002 GO_REF:0000117 MGI:3510291 RGD:1359026 NCBI chr 5:36,181,183...36,201,833
Ensembl chr 5:36,670,854...36,728,993
JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 involved_in IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000117 NCBI chr 5:36,223,429...36,242,187
Ensembl chr 5:36,670,854...36,728,993
JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:41,741,072...41,771,150
Ensembl chr 4:47,591,329...47,621,357
JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr19:13,327,569...13,336,286
Ensembl chr19:14,060,859...14,067,222
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) BHF-UCL PMID:25633902 NCBI chr14:44,969,573...45,041,296
Ensembl chr14:63,223,484...63,293,881
JBrowse link
G MTHFR methylenetetrahydrofolate reductase acts_upstream_of_or_within ISO (MGI:3510291|PMID:15217352) MGI PMID:15217352 MGI:3510291 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:1930456|PMID:11158293) RGD
UniProt
Ensembl
InterPro
MGI
PMID:11158293 PMID:11730351 PMID:15845641 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117 MGI:1930456 RGD:1359026 RGD:1601423 NCBI chr 1:212,353,195...212,463,304
Ensembl chr 1:217,358,050...217,460,946
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:8,195,868...8,228,071
Ensembl chr 5:8,017,403...8,049,322
JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHMT betaine--homocysteine S-methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:36,181,183...36,201,833
Ensembl chr 5:36,670,854...36,728,993
JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 involved_in ISO (PMID:18230605) BHF-UCL PMID:18230605 NCBI chr 5:36,223,429...36,242,187
Ensembl chr 5:36,670,854...36,728,993
JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADI1 acireductone dioxygenase 1 involved_in IEA Ensembl
UniProt
InterPro
GO_REF:0000002 GO_REF:0000041 GO_REF:0000104 GO_REF:0000107 NCBI chr2A:3,509,162...3,538,064
Ensembl chr2A:3,430,158...3,458,248
JBrowse link
G APIP APAF1 interacting protein involved_in IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000041 NCBI chr11:34,855,437...34,889,486
Ensembl chr11:34,730,671...34,764,732
JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt
Ensembl
InterPro
GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 NCBI chr 4:41,741,072...41,771,150
Ensembl chr 4:47,591,329...47,621,357
JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt GO_REF:0000041 NCBI chr19:13,327,569...13,336,286
Ensembl chr19:14,060,859...14,067,222
JBrowse link
G MTAP methylthioadenosine phosphorylase involved_in IEA UniProt GO_REF:0000041 GO_REF:0000104 NCBI chr 9:21,637,543...21,769,698
Ensembl chr 9:22,266,376...22,382,218
JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APIP APAF1 interacting protein involved_in IEA UniProt GO_REF:0000104 NCBI chr11:34,855,437...34,889,486
Ensembl chr11:34,730,671...34,764,732
JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr 4:41,741,072...41,771,150
Ensembl chr 4:47,591,329...47,621,357
JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr19:13,327,569...13,336,286
Ensembl chr19:14,060,859...14,067,222
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15229
    metabolic process 9937
      cellular metabolic process 8986
        organic acid metabolic process 847
          sulfur amino acid metabolic process 29
            sulfur amino acid biosynthetic process 14
              methionine biosynthetic process 11
                L-methionine biosynthetic process + 7
Path 2
Term Annotations click to browse term
  biological_process 15229
    metabolic process 9937
      cellular metabolic process 8986
        organic acid metabolic process 847
          oxoacid metabolic process 822
            carboxylic acid metabolic process 806
              cellular amino acid metabolic process 268
                alpha-amino acid metabolic process 172
                  aspartate family amino acid metabolic process 35
                    methionine metabolic process 13
                      methionine biosynthetic process 11
                        L-methionine biosynthetic process + 7
paths to the root