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ONTOLOGY REPORT - ANNOTATIONS

Term:methionine biosynthetic process
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Accession:GO:0009086 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
Synonyms:exact_synonym: methionine anabolism;   methionine biosynthesis;   methionine formation;   methionine synthesis

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methionine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase IDA
ISO		 (MGI:3510291|PMID:15217352) RGD PMID:15217352, PMID:15845641 MGI:3510291, RGD:1359026 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO (PMID:25633902) RGD PMID:25633902 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340 		JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:18,640,274...18,721,298
Ensembl chr14:18,640,277...18,720,357 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO
IBA		 MGI:2385823 (MGI:3510291|PMID:15217352)
PMID:21873635		 RGD PMID:15217352, PMID:21873635 MGI:3510291, RGD:13792537 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase IDA
ISO
IEA		 MGI:2180496 (MGI:1930456|PMID:11158293)
GO_REF:0000107
(PMID:23825108)		 RGD
Ensembl		 PMID:11158293 PMID:23825108, PMID:15845641, PMID:11730351 GO_REF:0000107 MGI:1930456, RGD:1359026, RGD:1601423 NCBI chr17:66,210,444...66,295,014
Ensembl chr17:66,210,461...66,295,014 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO
IBA		 (PMID:11466310)
PMID:21873635
(MGI:3710265|PMID:17369066)		 RGD PMID:11466310 PMID:17369066, PMID:21873635 MGI:3710265, RGD:13792537 NCBI chr 1:37,743,089...37,774,485
Ensembl chr 1:37,743,147...37,774,015 		JBrowse link
L-methionine salvage term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase ISO
IEA		 (PMID:18230605)
GO_REF:0000107		 RGD
Ensembl		 PMID:18230605 GO_REF:0000107 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 ISO
IEA		 (PMID:18230605)
GO_REF:0000107		 RGD
Ensembl		 PMID:18230605 GO_REF:0000107 NCBI chr 2:23,272,320...23,289,266
Ensembl chr 2:23,272,328...23,289,266 		JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 IEA
ISS
ISO		 GO_REF:0000041
GO_REF:0000024
(PMID:15938715)		 UniProt
RGD		 PMID:15938715 GO_REF:0000024 GO_REF:0000041 NCBI chr 6:47,940,211...47,947,173
Ensembl chr 6:47,940,183...47,947,230 		JBrowse link
G Apip APAF1 interacting protein IEA
IBA
ISO		 GO_REF:0000041
PMID:21873635
(PMID:22837397), (PMID:23285211)		 UniProt
RGD		 PMID:22837397 PMID:23285211, PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 3:92,969,128...92,998,104
Ensembl chr 3:92,969,141...92,995,483 		JBrowse link
G Enoph1 enolase-phosphatase 1 IEA
IBA
ISS
ISO		 GO_REF:0000041
PMID:21873635
GO_REF:0000024
(PMID:15843022)		 UniProt
RGD		 PMID:15843022, PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr14:11,172,359...11,198,799
Ensembl chr14:11,172,362...11,198,194 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 IEA
IBA		 GO_REF:0000041
PMID:21873635		 UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr19:25,360,299...25,366,283
Ensembl chr19:25,360,164...25,366,806 		JBrowse link
G Mtap methylthioadenosine phosphorylase IEA
IBA		 GO_REF:0000041
PMID:21873635		 UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 5:107,711,077...107,777,530
Ensembl chr 5:107,711,077...107,777,530 		JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:92,969,128...92,998,104
Ensembl chr 3:92,969,141...92,995,483 		JBrowse link
G Enoph1 enolase-phosphatase 1 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:11,172,359...11,198,799
Ensembl chr14:11,172,362...11,198,194 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr19:25,360,299...25,366,283
Ensembl chr19:25,360,164...25,366,806 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20044
    metabolic process 12101
      primary metabolic process 10847
        cellular amino acid metabolic process 269
          cellular amino acid biosynthetic process 65
            methionine biosynthetic process 12
              L-methionine biosynthetic process + 7
Path 2
Term Annotations click to browse term
  biological_process 20044
    metabolic process 12101
      cellular metabolic process 11040
        organic acid metabolic process 1013
          oxoacid metabolic process 975
            carboxylic acid metabolic process 956
              cellular amino acid metabolic process 269
                alpha-amino acid metabolic process 191
                  aspartate family amino acid metabolic process 41
                    methionine metabolic process 14
                      methionine biosynthetic process 12
                        L-methionine biosynthetic process + 7
paths to the root