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ONTOLOGY REPORT - ANNOTATIONS


Term:glutamine family amino acid biosynthetic process
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Accession:GO:0009084 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.
Synonyms:exact_synonym: glutamine family amino acid anabolism;   glutamine family amino acid biosynthesis;   glutamine family amino acid formation;   glutamine family amino acid synthesis


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arginine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asl argininosuccinate lyase NAS RGD PMID:2789519 RGD:632221 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Ass1 argininosuccinate synthase 1 IDA
IBA
ISO
IMP
IEA
PMID:21873635
(PMID:18473344), (PMID:27287393), (PMID:8792870)
PMID:19491403
GO_REF:0000041
RGD
UniProt
PMID:8792870, PMID:18473344, PMID:27287393, PMID:12470967, PMID:21873635, PMID:19491403 GO_REF:0000041, RGD:631755, RGD:13792537, RGD:12859071 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Nags N-acetylglutamate synthase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:90,084,607...90,089,693
Ensembl chr10:90,085,559...90,089,693
JBrowse link
arginine biosynthetic process via ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asl argininosuccinate lyase IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Otc ornithine carbamoyltransferase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:13,524,804...13,601,074
Ensembl chr  X:13,524,607...13,601,069
JBrowse link
glutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gls glutaminase IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
(PMID:16899818), (PMID:22049910)
GO_REF:0000024
(MGI:MGI:5320252|PMID:22228304)
Ensembl
RGD
UniProt
PMID:16899818, PMID:22049910, PMID:22228304, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5320252, RGD:13792537 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gls2 glutaminase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:2,605,679...2,621,853
Ensembl chr 7:2,605,719...2,621,852
JBrowse link
G Glud1 glutamate dehydrogenase 1 ISO (PMID:11032875) RGD PMID:11032875 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:19764902 RGD:13628741 NCBI chr 3:57,881,951...57,998,214
Ensembl chr 3:57,882,370...57,957,346
JBrowse link
glutamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glul glutamate-ammonia ligase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:4403443, PMID:21873635, PMID:28323 RGD:2301548, RGD:13792537, RGD:2301547 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Lgsn lengsin, lens protein with glutamine synthetase domain NOT IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:37,458,603...37,490,117
Ensembl chr 9:37,462,693...37,490,108
JBrowse link
L-proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:259,641,673...259,674,521
Ensembl chr 1:259,641,676...259,674,425
Ensembl chr 1:259,641,676...259,674,425
JBrowse link
G LOC108348083 delta-1-pyrroline-5-carboxylate synthase IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:259,057,407...259,089,727
Ensembl chr 1:259,057,402...259,089,642
JBrowse link
G Noxred1 NADP-dependent oxidoreductase domain containing 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:111,243,232...111,271,107
Ensembl chr 6:111,243,228...111,267,734
JBrowse link
G Oat ornithine aminotransferase IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr10:109,817,300...109,822,218
Ensembl chr10:109,818,177...109,821,807
JBrowse link
G Pycr2 pyrroline-5-carboxylate reductase 2 IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr13:99,184,624...99,188,418
Ensembl chr13:99,184,564...99,188,431
JBrowse link
G Pycr3 pyrroline-5-carboxylate reductase 3 IEA
IBA
ISS
ISO
GO_REF:0000041
PMID:21873635
GO_REF:0000024
(PMID:23024808)
UniProt
RGD
PMID:23024808, PMID:21873635 GO_REF:0000024, GO_REF:0000041, RGD:13792537 NCBI chr 7:116,949,882...116,955,150
Ensembl chr 7:116,949,879...116,955,148
JBrowse link
proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761, PMID:26297558 NCBI chr 1:259,641,673...259,674,521
Ensembl chr 1:259,641,676...259,674,425
Ensembl chr 1:259,641,676...259,674,425
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 ISO (PMID:16730026) RGD PMID:16730026 NCBI chr10:109,817,300...109,822,218
Ensembl chr10:109,818,177...109,821,807
JBrowse link
G Pycr2 pyrroline-5-carboxylate reductase 2 ISO
ISS
(PMID:23024808)
GO_REF:0000024
RGD
UniProt
PMID:23024808 GO_REF:0000024 NCBI chr13:99,184,624...99,188,418
Ensembl chr13:99,184,564...99,188,431
JBrowse link
regulation of arginine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:MGI:4830440|PMID:19284480) RGD PMID:19284480 MGI:MGI:4830440 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      primary metabolic process 10920
        cellular amino acid metabolic process 276
          cellular amino acid biosynthetic process 71
            alpha-amino acid biosynthetic process 66
              glutamine family amino acid biosynthetic process 18
                arginine biosynthetic process + 5
                glutamate biosynthetic process + 4
                glutamine biosynthetic process + 2
                proline biosynthetic process + 7
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      cellular metabolic process 11085
        organic acid metabolic process 1095
          oxoacid metabolic process 1066
            carboxylic acid metabolic process 1009
              carboxylic acid biosynthetic process 318
                cellular amino acid biosynthetic process 71
                  alpha-amino acid biosynthetic process 66
                    glutamine family amino acid biosynthetic process 18
                      arginine biosynthetic process + 5
                      glutamate biosynthetic process + 4
                      glutamine biosynthetic process + 2
                      proline biosynthetic process + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.