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ONTOLOGY REPORT - ANNOTATIONS

Term:branched-chain amino acid catabolic process
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Accession:GO:0009083 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
Synonyms:exact_synonym: branched chain family amino acid breakdown;   branched chain family amino acid catabolic process;   branched chain family amino acid catabolism;   branched chain family amino acid degradation

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branched-chain amino acid catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Auh AU RNA binding methylglutaconyl-CoA hydratase IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:12,310,178...12,405,224
Ensembl chr17:12,310,214...12,405,205 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 ISO (MGI:3027291|PMID:14755340) RGD PMID:14755340 MGI:3027291 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795 		JBrowse link
G Bcat2 branched chain amino acid transaminase 2 IDA
ISO		 MGI:3028726 (MGI:3027291|PMID:14755340) RGD PMID:14755340, PMID:11733007 MGI:3027291, RGD:1582175 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080 		JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha TAS
IBA
IEA
ISS
ISO		 PMID:21873635
GO_REF:0000002
GO_REF:0000024
(PMID:7883996)		 InterPro
HGNC
RGD		 PMID:7883996, PMID:2822716, PMID:21873635 GO_REF:0000002 GO_REF:0000024, RGD:631719, RGD:13792537 NCBI chr 1:82,423,291...82,452,094
Ensembl chr 1:82,423,277...82,452,281 		JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta ISO
IBA
ISS
IEA		 (PMID:2022752)
PMID:21873635
GO_REF:0000024
GO_REF:0000107		 RGD
HGNC
Ensembl		 PMID:2022752, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 8:91,464,229...91,656,134
Ensembl chr 8:91,464,229...91,656,134 		JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase TAS
IDA		 PMID:1377677 RGD
HGNC		 PMID:11562470, PMID:1377677 RGD:68918, RGD:68712 NCBI chr 1:199,351,628...199,356,299
Ensembl chr 1:199,351,628...199,356,881 		JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:82,604,369...82,702,429
Ensembl chr 4:82,604,373...82,702,429 		JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:53,446,185...53,526,727
Ensembl chr 9:53,446,194...53,526,728 		JBrowse link
G Ivd isovaleryl-CoA dehydrogenase ISO (PMID:7640268) RGD PMID:7640268 NCBI chr 3:110,669,355...110,689,789
Ensembl chr 3:110,669,312...110,690,173 		JBrowse link
G Slc25a44 solute carrier family 25, member 44 ISO (PMID:31435015)
(MGI:6359503|PMID:31435015)		 RGD PMID:31435015 MGI:6359503 NCBI chr 2:187,772,013...187,786,829
Ensembl chr 2:187,774,062...187,786,731 		JBrowse link
isoleucine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadsb acyl-CoA dehydrogenase, short/branched chain ISO
IEA
ISS		 (PMID:11013134)
GO_REF:0000041
GO_REF:0000024		 RGD
UniProt		 PMID:11013134 GO_REF:0000024 GO_REF:0000041 NCBI chr 1:201,981,362...202,022,771
Ensembl chr 1:201,981,357...202,021,008 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 ISO (PMID:1979337), (PMID:8103405) RGD PMID:1979337 PMID:8103405 NCBI chr 8:58,166,990...58,195,884
Ensembl chr 8:58,166,990...58,195,884 		JBrowse link
G Bcat2 branched chain amino acid transaminase 2 IDA
ISO
IEA		 MGI:3772355 (MGI:3770498|PMID:17767905)
GO_REF:0000107		 RGD
Ensembl		 PMID:17767905, PMID:11733007 GO_REF:0000107 MGI:3770498, RGD:1582175 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080 		JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase IMP RGD PMID:27472223 RGD:39131293 NCBI chr 1:199,351,628...199,356,299
Ensembl chr 1:199,351,628...199,356,881 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 ISO
IEA
ISS		 (PMID:18996107), (PMID:19706438)
GO_REF:0000107
GO_REF:0000041
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:18996107 PMID:19706438 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr  X:21,696,796...21,699,241
Ensembl chr  X:21,696,772...21,699,241 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20045
    metabolic process 12102
      cellular metabolic process 11041
        organic acid metabolic process 1013
          branched-chain amino acid metabolic process 16
            branched-chain amino acid catabolic process 13
              D-leucine catabolic process 0
              D-valine catabolic process 0
              branched-chain amino acid catabolic process to alcohol via Ehrlich pathway 0
              branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway 0
              isoleucine catabolic process 5
              valine catabolic process to isobutanol 0
paths to the root