Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:branched-chain amino acid catabolic process
go back to main search page
Accession:GO:0009083 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
Synonyms:exact_synonym: branched chain family amino acid breakdown;   branched chain family amino acid catabolic process;   branched chain family amino acid catabolism;   branched chain family amino acid degradation



show annotations for term's descendants           Sort by:
 
branched-chain amino acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Auh AU RNA binding methylglutaconyl-CoA hydratase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:12,329,522...12,424,896
Ensembl chr17:12,329,524...12,424,896
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 acts_upstream_of_or_within ISO (MGI:3027291|PMID:14755340) RGD PMID:14755340 MGI:3027291 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 acts_upstream_of_or_within IDA
ISO
MGI:3028726 (MGI:3027291|PMID:14755340) RGD PMID:14755340 PMID:11733007 MGI:3027291, RGD:1582175 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha involved_in TAS
ISO
IEA
IBA
ISS
(PMID:3593587), (PMID:7883996)
GO_REF:0000002
PMID:21873635
GO_REF:0000024
RGD
InterPro
HGNC-UCL
PMID:3593587 PMID:7883996 PMID:2822716 PMID:21873635 GO_REF:0000002 GO_REF:0000024, RGD:631719, RGD:13792537 NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862
JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta involved_in ISS
ISO
IEA
IBA
GO_REF:0000024
(PMID:2022752), (PMID:3593587)
GO_REF:0000107
PMID:21873635
HGNC-UCL
RGD
Ensembl
PMID:2022752 PMID:3593587 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 8:84,845,264...85,027,812
Ensembl chr 8:84,845,264...85,027,812
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase involved_in TAS
IDA
PMID:1377677 RGD
HGNC-UCL
PMID:11562470 PMID:1377677 RGD:68918, RGD:68712 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 involved_in ISO
IEA
(PMID:3593587)
GO_REF:0000107
RGD
Ensembl
PMID:3593587 GO_REF:0000107 NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609
JBrowse link
G Dld dihydrolipoamide dehydrogenase involved_in ISO (PMID:3593587) RGD PMID:3593587 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:81,649,180...81,747,244
Ensembl chr 4:81,649,175...81,780,617
JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824
JBrowse link
G Ivd isovaleryl-CoA dehydrogenase involved_in ISO (PMID:7640268) RGD PMID:7640268 NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
JBrowse link
G Slc25a44 solute carrier family 25, member 44 involved_in ISO (PMID:31435015)
(MGI:6359503|PMID:31435015)
RGD PMID:31435015 MGI:6359503 NCBI chr 2:173,868,317...173,883,137
Ensembl chr 2:173,868,320...173,883,020
JBrowse link
isoleucine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadsb acyl-CoA dehydrogenase, short/branched chain involved_in ISO
IEA
ISS
(PMID:11013134)
GO_REF:0000107
GO_REF:0000041
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:11013134 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:1979337), (PMID:8103405) RGD PMID:1979337 PMID:8103405 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 acts_upstream_of_or_within
involved_in
IDA
ISO
IEA
MGI:3772355 (MGI:3770498|PMID:17767905)
GO_REF:0000107
RGD
Ensembl
PMID:17767905 PMID:11733007 GO_REF:0000107 MGI:3770498, RGD:1582175 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase IMP RGD PMID:27472223 RGD:39131293 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 involved_in ISO
IEA
ISS
(PMID:18996107), (PMID:19706438)
GO_REF:0000107
GO_REF:0000041
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:18996107 PMID:19706438 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr  X:21,089,152...21,091,597
Ensembl chr  X:21,089,122...21,109,488
JBrowse link
leucine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Auh AU RNA binding methylglutaconyl-CoA hydratase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr17:12,329,522...12,424,896
Ensembl chr17:12,329,524...12,424,896
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase IMP RGD PMID:27472223 RGD:39131293 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:148,178,203...148,192,072
Ensembl chr 5:148,178,252...148,192,068
JBrowse link
G Hmgcll1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:76,757,301...76,887,300
Ensembl chr 8:76,757,497...76,886,816
JBrowse link
G Ivd isovaleryl-CoA dehydrogenase involved_in IEA
IBA
IDA
ISO
GO_REF:0000041
PMID:21873635
PMID:6401713
(PMID:7640268)
UniProt
RGD
PMID:7640268 PMID:21873635 PMID:6401713 GO_REF:0000041, RGD:13792537, RGD:8554099 NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
JBrowse link
G Mccc1 methylcrotonyl-CoA carboxylase subunit 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:118,799,147...118,851,181
Ensembl chr 2:118,799,150...118,851,222
JBrowse link
G Mccc2 methylcrotonyl-CoA carboxylase subunit 2 involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972
JBrowse link
valine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 involved_in IDA
IEA
ISO
IBA
GO_REF:0000107
(PMID:23835272)
PMID:21873635
Ensembl
RGD
PMID:23835272 PMID:2768248 PMID:21873635 GO_REF:0000107, RGD:1599052, RGD:13792537 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase IMP RGD PMID:27472223 RGD:39131293 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase involved_in IBA
ISS
ISO
IEA
PMID:21873635
GO_REF:0000024
(PMID:16466957)
GO_REF:0000041
UniProt
RGD
PMID:16466957 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr 4:81,649,180...81,747,244
Ensembl chr 4:81,649,175...81,780,617
JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      primary metabolic process 10535
        cellular amino acid metabolic process 277
          branched-chain amino acid metabolic process 24
            branched-chain amino acid catabolic process 20
              branched-chain amino acid catabolic process to alcohol via Ehrlich pathway 0
              branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway 0
              isoleucine catabolic process 5
              leucine catabolic process + 7
              valine catabolic process + 4
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      organic substance metabolic process 11355
        organic acid metabolic process 1013
          oxoacid metabolic process 982
            carboxylic acid metabolic process 961
              carboxylic acid catabolic process 233
                cellular amino acid catabolic process 107
                  branched-chain amino acid catabolic process 20
                    branched-chain amino acid catabolic process to alcohol via Ehrlich pathway 0
                    branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway 0
                    isoleucine catabolic process 5
                    leucine catabolic process + 7
                    valine catabolic process + 4
paths to the root