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ONTOLOGY REPORT - ANNOTATIONS


Term:branched-chain amino acid metabolic process
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Accession:GO:0009081 term browser browse the term
Definition:The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
Synonyms:exact_synonym: branched chain family amino acid metabolism



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branched-chain amino acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat2 branched chain amino acid transaminase 2 acts_upstream_of_or_within TAS
ISO
MGI:3772355 (MGI:4442298|PMID:20237068) RGD PMID:20237068 PMID:11171603 MGI:4442298, RGD:62398 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
branched-chain amino acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat1 branched chain amino acid transaminase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
branched-chain amino acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat1 branched chain amino acid transaminase 1 acts_upstream_of_or_within ISO (MGI:3027291|PMID:14755340) RGD PMID:14755340 MGI:3027291 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 acts_upstream_of_or_within IDA
ISO
MGI:3028726 (MGI:3027291|PMID:14755340) RGD PMID:14755340 PMID:11733007 MGI:3027291, RGD:1582175 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha involved_in TAS
IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
(PMID:3593587), (PMID:7883996)
GO_REF:0000024
Ensembl
RGD
HGNC-UCL
PMID:3593587 PMID:7883996 PMID:2822716 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:631719, RGD:13792537 NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862
JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
PMID:21873635
GO_REF:0000107
(PMID:2022752), (PMID:3593587)
HGNC-UCL
Ensembl
RGD
PMID:2022752 PMID:3593587 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 8:84,845,264...85,027,812
Ensembl chr 8:84,845,264...85,027,812
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase involved_in TAS
IDA
PMID:1377677 RGD
HGNC-UCL
PMID:11562470 PMID:1377677 RGD:68918, RGD:68712 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 involved_in ISO (PMID:3593587) RGD PMID:3593587 NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609
JBrowse link
G Dld dihydrolipoamide dehydrogenase involved_in ISO (PMID:3593587) RGD PMID:3593587 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
JBrowse link
G Ivd isovaleryl-CoA dehydrogenase involved_in ISO (PMID:7640268) RGD PMID:7640268 NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
JBrowse link
G Slc25a44 solute carrier family 25, member 44 involved_in ISO (PMID:31435015)
(MGI:6359503|PMID:31435015)
RGD PMID:31435015 MGI:6359503 NCBI chr 2:173,868,317...173,883,137
Ensembl chr 2:173,868,320...173,883,020
JBrowse link
isoleucine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ilvbl ilvB acetolactate synthase like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:11,039,870...11,049,924
Ensembl chr 7:11,039,871...11,049,924
JBrowse link
G Sds serine dehydratase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
JBrowse link
G Sdsl serine dehydratase-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:36,099,693...36,109,914
Ensembl chr12:36,099,693...36,109,906
JBrowse link
isoleucine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadsb acyl-CoA dehydrogenase, short/branched chain involved_in ISO
IEA
ISS
(PMID:11013134)
GO_REF:0000107
GO_REF:0000041
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:11013134 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:1979337), (PMID:8103405) RGD PMID:1979337 PMID:8103405 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 acts_upstream_of_or_within IDA
ISO
MGI:3772355 (MGI:3770498|PMID:17767905) RGD PMID:17767905 PMID:11733007 MGI:3770498, RGD:1582175 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase IMP RGD PMID:27472223 RGD:39131293 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 involved_in ISO
IEA
ISS
(PMID:18996107), (PMID:19706438)
GO_REF:0000041
GO_REF:0000024
RGD
UniProt
PMID:18996107 PMID:19706438 GO_REF:0000024 GO_REF:0000041 NCBI chr  X:21,089,152...21,091,597
Ensembl chr  X:21,089,122...21,109,488
JBrowse link
isoleucine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat2 branched chain amino acid transaminase 2 acts_upstream_of_or_within ISO MGI:3028726 (MGI:3027291|PMID:14755340) RGD PMID:14755340 MGI:3027291 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
leucine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat1 branched chain amino acid transaminase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:11733007 PMID:21873635 RGD:1582175, RGD:13792537 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
leucine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Auh AU RNA binding methylglutaconyl-CoA hydratase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr17:12,329,522...12,424,896
Ensembl chr17:12,329,524...12,424,896
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase IMP RGD PMID:27472223 RGD:39131293 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:148,178,203...148,192,072
Ensembl chr 5:148,178,252...148,192,068
JBrowse link
G Hmgcll1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:76,757,301...76,887,300
Ensembl chr 8:76,757,497...76,886,816
JBrowse link
G Ivd isovaleryl-CoA dehydrogenase involved_in IEA
IBA
IDA
ISO
GO_REF:0000041
PMID:21873635
PMID:6401713
(PMID:7640268)
UniProt
RGD
PMID:7640268 PMID:21873635 PMID:6401713 GO_REF:0000041, RGD:13792537, RGD:8554099 NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
JBrowse link
G Mccc1 methylcrotonyl-CoA carboxylase subunit 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:118,799,147...118,851,181
Ensembl chr 2:118,799,150...118,851,222
JBrowse link
G Mccc2 methylcrotonyl-CoA carboxylase subunit 2 involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972
JBrowse link
leucine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat2 branched chain amino acid transaminase 2 acts_upstream_of_or_within ISO MGI:3028726|MGI:3772355 (MGI:3027291|PMID:14755340), (MGI:3770498|PMID:17767905) RGD PMID:14755340 PMID:17767905 MGI:3027291 MGI:3770498 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
G Dao D-amino-acid oxidase acts_upstream_of_or_within ISO MGI:3528694 (MGI:3525958|PMID:15026304) RGD PMID:15026304 MGI:3525958 NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741
JBrowse link
G Ivd isovaleryl-CoA dehydrogenase TAS RGD PMID:2777793 RGD:631718 NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
JBrowse link
valine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat1 branched chain amino acid transaminase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
G Ilvbl ilvB acetolactate synthase like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:11,039,870...11,049,924
Ensembl chr 7:11,039,871...11,049,924
JBrowse link
valine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 involved_in IDA
IEA
ISO
IBA
GO_REF:0000107
(PMID:23835272)
PMID:21873635
Ensembl
RGD
PMID:23835272 PMID:2768248 PMID:21873635 GO_REF:0000107, RGD:1599052, RGD:13792537 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase IMP RGD PMID:27472223 RGD:39131293 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase involved_in IBA
ISS
ISO
IEA
PMID:21873635
GO_REF:0000024
(PMID:16466957)
GO_REF:0000041
UniProt
RGD
PMID:16466957 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr 4:81,649,180...81,747,244
Ensembl chr 4:81,649,175...81,780,617
JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824
JBrowse link
valine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 involved_in IDA PMID:2768248 UniProt PMID:2768248 RGD:1599052 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 acts_upstream_of_or_within ISO MGI:3028726|MGI:3772355 (MGI:3027291|PMID:14755340), (MGI:3770498|PMID:17767905) RGD PMID:14755340 PMID:17767905 MGI:3027291 MGI:3770498 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    metabolic process 11458
      primary metabolic process 10260
        cellular amino acid metabolic process 273
          branched-chain amino acid metabolic process 24
            branched-chain amino acid biosynthetic process + 5
            branched-chain amino acid catabolic process + 20
            isoleucine metabolic process + 8
            leucine metabolic process + 10
            valine metabolic process + 7
Path 2
Term Annotations click to browse term
  biological_process 18734
    metabolic process 11458
      cellular metabolic process 9697
        organic acid metabolic process 1010
          oxoacid metabolic process 982
            carboxylic acid metabolic process 967
              cellular amino acid metabolic process 273
                branched-chain amino acid metabolic process 24
                  branched-chain amino acid biosynthetic process + 5
                  branched-chain amino acid catabolic process + 20
                  isoleucine metabolic process + 8
                  leucine metabolic process + 10
                  valine metabolic process + 7
paths to the root