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ONTOLOGY REPORT - ANNOTATIONS


Term:aromatic amino acid family catabolic process
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Accession:GO:0009074 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
Synonyms:exact_synonym: aromatic amino acid family breakdown;   aromatic amino acid family catabolism;   aromatic amino acid family degradation


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L-phenylalanine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASRGL1 asparaginase and isoaspartyl peptidase 1 TAS Reactome Reactome:R-HSA-71182 NCBI chr11:62,337,430...62,401,401
Ensembl chr11:62,337,448...62,393,412
JBrowse link
G FAH fumarylacetoacetate hydrolase TAS
IBA
IEA
(PMID:21873635) Reactome
GO_Central
UniProtKB
PMID:21873635 GO_REF:0000041 Reactome:R-HSA-71182 NCBI chr15:80,152,789...80,186,949
Ensembl chr15:80,152,490...80,186,946
JBrowse link
G GSTZ1 glutathione S-transferase zeta 1 TAS
IBA
IEA
(PMID:21873635) Reactome
GO_Central
UniProtKB
PMID:21873635 GO_REF:0000041 Reactome:R-HSA-71182 NCBI chr14:77,321,002...77,331,597
Ensembl chr14:77,320,996...77,331,597
JBrowse link
G HGD homogentisate 1,2-dioxygenase TAS
IBA
IEA
(PMID:21873635) Reactome
GO_Central
UniProtKB
PMID:21873635 GO_REF:0000041 Reactome:R-HSA-71182 NCBI chr 3:120,628,168...120,682,555
Ensembl chr 3:120,628,172...120,682,269
JBrowse link
G HPD 4-hydroxyphenylpyruvate dioxygenase TAS
IEA
Reactome
UniProtKB
GO_REF:0000041 Reactome:R-HSA-71182 NCBI chr12:121,839,527...121,888,611
Ensembl chr12:121,839,527...121,863,596
JBrowse link
G IL4I1 interleukin 4 induced 1 TAS Reactome Reactome:R-HSA-71182 NCBI chr19:49,889,654...49,929,504
Ensembl chr19:49,889,654...49,929,539
JBrowse link
G KYAT1 kynurenine aminotransferase 1 TAS Reactome Reactome:R-HSA-71182 NCBI chr 9:128,832,942...128,882,523
Ensembl chr 9:128,819,663...128,881,931
Ensembl chr 9:128,819,663...128,881,931
JBrowse link
G PAH phenylalanine hydroxylase TAS
IEA
Reactome
UniProtKB
GO_REF:0000041 Reactome:R-HSA-71182 NCBI chr12:102,836,889...102,958,441
Ensembl chr12:102,836,889...102,958,410
JBrowse link
G PCBD1 pterin-4 alpha-carbinolamine dehydratase 1 TAS Reactome Reactome:R-HSA-71182 NCBI chr10:70,882,280...70,888,565
Ensembl chr10:70,882,280...70,888,565
JBrowse link
G QDPR quinoid dihydropteridine reductase TAS
IBA
(PMID:21873635) Reactome
GO_Central
PMID:21873635 Reactome:R-HSA-71182 NCBI chr 4:17,486,395...17,512,090
Ensembl chr 4:17,460,261...17,512,206
JBrowse link
G TAT tyrosine aminotransferase TAS
IEA
Reactome
UniProtKB
GO_REF:0000041 Reactome:R-HSA-71182 NCBI chr16:71,565,660...71,577,092
Ensembl chr16:71,565,660...71,577,092
JBrowse link
tryptophan catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAT aminoadipate aminotransferase TAS Reactome Reactome:R-HSA-71240 NCBI chr 4:170,060,222...170,091,699
Ensembl chr 4:170,060,222...170,091,699
JBrowse link
G ACMSD aminocarboxymuconate semialdehyde decarboxylase TAS (PMID:12140278), (PMID:19843166) ParkinsonsUK-UCL PMID:12140278 PMID:19843166 NCBI chr 2:134,838,319...134,902,906
Ensembl chr 2:134,838,616...134,902,034
JBrowse link
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase TAS Reactome Reactome:R-HSA-71240 NCBI chr 2:42,767,087...42,801,002
Ensembl chr 2:42,767,089...42,792,593
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 TAS Reactome Reactome:R-HSA-71240 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790
JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 TAS Reactome Reactome:R-HSA-71240 NCBI chr 8:39,934,955...40,016,391
Ensembl chr 8:39,934,614...40,016,391
JBrowse link
G KMO kynurenine 3-monooxygenase TAS Reactome Reactome:R-HSA-71240 NCBI chr 1:241,531,883...241,595,642
Ensembl chr 1:241,532,134...241,595,642
JBrowse link
G KYAT1 kynurenine aminotransferase 1 TAS Reactome Reactome:R-HSA-71240 NCBI chr 9:128,832,942...128,882,523
Ensembl chr 9:128,819,663...128,881,931
Ensembl chr 9:128,819,663...128,881,931
JBrowse link
G KYNU kynureninase IEA
IMP
TAS
(PMID:17334708) InterPro
UniProtKB
Reactome
PMID:17334708 GO_REF:0000002 Reactome:R-HSA-71240 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase TAS Reactome Reactome:R-HSA-71240 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
JBrowse link
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KYNU kynureninase IEA Ensembl GO_REF:0000107 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFMID arylformamidase IEA
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr17:78,185,102...78,207,702
Ensembl chr17:78,187,317...78,207,701
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 IEA
IBA
(PMID:21873635) InterPro
GO_Central
UniProtKB
PMID:21873635 GO_REF:0000002 GO_REF:0000041 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790
JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 IEA
IBA
ISS
IDA
(PMID:21873635)
(PMID:17499941)
(PMID:17671174)
InterPro
GO_Central
UniProtKB
PMID:17499941 PMID:17671174 PMID:21873635 GO_REF:0000002 GO_REF:0000041 NCBI chr 8:39,934,955...40,016,391
Ensembl chr 8:39,934,614...40,016,391
JBrowse link
G KYNU kynureninase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase IEA
IDA
(PMID:27762317) InterPro
UniProtKB
PMID:27762317 GO_REF:0000002 GO_REF:0000041 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
JBrowse link
tyrosine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAH fumarylacetoacetate hydrolase IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000104 NCBI chr15:80,152,789...80,186,949
Ensembl chr15:80,152,490...80,186,946
JBrowse link
G GSTZ1 glutathione S-transferase zeta 1 IEA UniProt GO_REF:0000043 NCBI chr14:77,321,002...77,331,597
Ensembl chr14:77,320,996...77,331,597
JBrowse link
G HGD homogentisate 1,2-dioxygenase IEA UniProt GO_REF:0000043 NCBI chr 3:120,628,168...120,682,555
Ensembl chr 3:120,628,172...120,682,269
JBrowse link
G HPD 4-hydroxyphenylpyruvate dioxygenase IEA
IBA
ISS
(PMID:21873635) Ensembl
GO_Central
UniProtKB
PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr12:121,839,527...121,888,611
Ensembl chr12:121,839,527...121,863,596
JBrowse link
G TAT tyrosine aminotransferase IDA (PMID:7999802) UniProtKB PMID:7999802 NCBI chr16:71,565,660...71,577,092
Ensembl chr16:71,565,660...71,577,092
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 18673
    metabolic process 12182
      cellular metabolic process 11132
        organic acid metabolic process 1145
          aromatic amino acid family metabolic process 34
            aromatic amino acid family catabolic process 20
              L-phenylalanine catabolic process + 11
              anthranilate catabolic process 0
              aromatic amino acid family catabolic process to alcohol via Ehrlich pathway 0
              aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway 0
              tryptophan catabolic process + 10
              tyrosine catabolic process + 5
paths to the root