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ONTOLOGY REPORT - ANNOTATIONS


Term:aromatic amino acid family metabolic process
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Accession:GO:0009072 term browser browse the term
Definition:The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
Synonyms:exact_synonym: aromatic amino acid family metabolism


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anthranilate metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kynu kynureninase ISO (PMID:11985583) UniProtKB PMID:11985583 NCBI chrNW_004936469:33,632,885...33,805,158 JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase ISO PMID:11943812
(MGI:2386819|PMID:9520487)
(MGI:72094|PMID:7715703), (MGI:77787|PMID:7592982)
BHF-UCL
MGI
RGD
PMID:2427363, PMID:7592982, PMID:7715703, PMID:9520487, PMID:11943812, PMID:19584816 MGI:2386819, MGI:72094, MGI:77787, RGD:1580046, RGD:5129111, RGD:5130972 NCBI chrNW_004936794:478,651...486,887 JBrowse link
L-phenylalanine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Qdpr quinoid dihydropteridine reductase ISO RGD PMID:4155291 RGD:5128604 NCBI chrNW_004936477:10,687,328...10,708,015 JBrowse link
L-phenylalanine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase ISO RGD PMID:16953590 RGD:1601531 NCBI chrNW_004936492:11,342,566...11,412,323 JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 ISO PMID:1465414 CAFA PMID:1465414 RGD:12792994 NCBI chrNW_004936521:7,843,945...7,847,827 JBrowse link
G Spr sepiapterin reductase ISO (MGI:3722569|PMID:16532389) MGI PMID:16532389 MGI:3722569 NCBI chrNW_004936491:16,693,940...16,699,040 JBrowse link
melanin biosynthetic process from tyrosine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dct dopachrome tautomerase ISO (MGI:3690794|PMID:2169885) UniProt PMID:2169885 MGI:3690794 NCBI chrNW_004936472:15,074,947...15,110,427 JBrowse link
positive regulation of L-dopa biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase ISO (PMID:16731528) ParkinsonsUK-UCL PMID:16731528 NCBI chrNW_004936623:2,422,780...2,436,817 JBrowse link
tryptophan catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase ISO RGD PMID:11802786 RGD:70243 NCBI chrNW_004936469:40,858,338...40,904,807 JBrowse link
G Kynu kynureninase ISO (PMID:17334708) UniProtKB PMID:17334708 NCBI chrNW_004936469:33,632,885...33,805,158 JBrowse link
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kynu kynureninase ISO RGD PMID:7236232 RGD:2303721 NCBI chrNW_004936469:33,632,885...33,805,158 JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase ISO RGD PMID:7236232 RGD:2303721 NCBI chrNW_004936576:2,537,702...2,555,790 JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase ISO (MGI:3587527|PMID:15866519) MGI PMID:15866519 MGI:3587527 NCBI chrNW_004936594:2,794,927...2,805,689 JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 ISO (MGI:2151782|PMID:2419335), (MGI:2156954|PMID:11751753) RGD
MGI
PMID:2419335, PMID:10719243, PMID:11513477, PMID:11751753 MGI:2151782, MGI:2156954, RGD:2290190, RGD:2290543 NCBI chrNW_004936843:658,058...672,662 JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 ISO (PMID:17671174)
(MGI:3719924|PMID:17671174)
(MGI:3712725|PMID:17499941)
UniProtKB
MGI
PMID:17499941, PMID:17671174 MGI:3712725, MGI:3719924 NCBI chrNW_004936843:595,237...649,390 JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase ISO (PMID:27762317) UniProtKB PMID:27762317 NCBI chrNW_004936576:2,537,702...2,555,790 JBrowse link
tryptophan metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO (MGI:53851|PMID:4147174) MGI PMID:4147174 MGI:53851 NCBI chrNW_004936683:2,874,022...2,936,214 JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase ISO RGD PMID:3400092, PMID:3899109, PMID:10719243 RGD:2290190, RGD:2290313, RGD:2291804 NCBI chrNW_004936576:2,537,702...2,555,790 JBrowse link
tyrosine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase ISO RGD PMID:16953590 RGD:1601531 NCBI chrNW_004936492:11,342,566...11,412,323 JBrowse link
tyrosine biosynthetic process, by oxidation of phenylalanine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase ISO RGD PMID:10839989 RGD:1601535 NCBI chrNW_004936492:11,342,566...11,412,323 JBrowse link
tyrosine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tat tyrosine aminotransferase ISO (PMID:7999802)
(MGI:5430853|PMID:21153519)
UniProtKB
UniProt
PMID:7999802, PMID:21153519 MGI:5430853 NCBI chrNW_004936475:22,190,282...22,199,398 JBrowse link
tyrosine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO (MGI:53851|PMID:4147174) MGI PMID:4147174 MGI:53851 NCBI chrNW_004936683:2,874,022...2,936,214 JBrowse link
G Iyd iodotyrosine deiodinase ISO (PMID:25395621) UniProt
UniProtKB
PMID:25395621 NCBI chrNW_004936489:3,454,757...3,472,423 JBrowse link
G Thap4 THAP domain containing 4 ISO (PMID:30524950) UniProt PMID:30524950 NCBI chrNW_004936745:316,145...318,559 JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 ISO (MGI:6362140|PMID:31537781) MGI PMID:31537781 MGI:6362140 NCBI chrNW_004936542:3,567,469...3,571,393 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12002
    metabolic process 7668
      cellular metabolic process 7071
        organic acid metabolic process 639
          aromatic amino acid family metabolic process 18
            L-dopa metabolic process + 1
            L-phenylalanine metabolic process + 4
            anthranilate metabolic process + 1
            aromatic amino acid family biosynthetic process + 2
            aromatic amino acid family catabolic process + 8
            gliotoxin biosynthetic process + 0
            para-aminobenzoic acid metabolic process + 0
            tryptophan metabolic process + 7
            tyrosine metabolic process + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.