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ONTOLOGY REPORT - ANNOTATIONS


Term:aromatic amino acid family metabolic process
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Accession:GO:0009072 term browser browse the term
Definition:The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
Synonyms:exact_synonym: aromatic amino acid family metabolism


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aromatic amino acid family metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fah fumarylacetoacetate hydrolase IEA UniProt GO_REF:0000002, MGI:2152098 NCBI chr 7:84,585,159...84,605,942
Ensembl chr 7:84,585,159...84,606,722
JBrowse link
G Gstz1 glutathione transferase zeta 1 (maleylacetoacetate isomerase) IEA UniProt GO_REF:0000002, MGI:2152098 NCBI chr12:87,147,161...87,164,723
Ensembl chr12:87,147,165...87,164,723
JBrowse link
G Hpd 4-hydroxyphenylpyruvic acid dioxygenase IEA UniProt GO_REF:0000002, MGI:2152098 NCBI chr 5:123,171,807...123,182,723
Ensembl chr 5:123,171,807...123,182,727
JBrowse link
G Hpdl 4-hydroxyphenylpyruvate dioxygenase-like IEA UniProt GO_REF:0000002, MGI:2152098 NCBI chr 4:116,819,907...116,821,508
Ensembl chr 4:116,819,904...116,821,707
JBrowse link
G Il4i1 interleukin 4 induced 1 IDA (MGI:3505621|PMID:15383589) MGI PMID:15383589 MGI:3505621 NCBI chr 7:44,836,288...44,840,809
Ensembl chr 7:44,816,387...44,840,809
JBrowse link
G Pah phenylalanine hydroxylase IEA UniProt GO_REF:0000002, MGI:2152098 NCBI chr10:87,521,795...87,584,137
Ensembl chr10:87,521,795...87,584,136
JBrowse link
G Tat tyrosine aminotransferase IEA UniProt GO_REF:0000002, MGI:2152098 NCBI chr 8:109,986,078...109,999,804
Ensembl chr 8:109,990,437...109,999,803
JBrowse link
G Th tyrosine hydroxylase IEA UniProt GO_REF:0000002, MGI:2152098 NCBI chr 7:142,892,779...142,899,995
Ensembl chr 7:142,892,752...142,931,128
JBrowse link
G Tph1 tryptophan hydroxylase 1 IEA UniProt GO_REF:0000002, MGI:2152098 NCBI chr 7:46,644,641...46,672,537
Ensembl chr 7:46,644,641...46,672,537
JBrowse link
G Tph2 tryptophan hydroxylase 2 IEA UniProt GO_REF:0000002, MGI:2152098 NCBI chr10:115,078,641...115,185,022
Ensembl chr10:115,078,641...115,185,022
JBrowse link
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr17:83,831,348...83,848,981
Ensembl chr17:83,831,156...83,847,963
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 8:24,584,133...24,596,952
Ensembl chr 8:24,584,136...24,597,009
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 8:24,531,892...24,576,414
Ensembl chr 8:24,531,892...24,576,333
JBrowse link
anthranilate metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kynu kynureninase ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096, MGI:4834177, MGI:6201960 NCBI chr 2:43,555,258...43,683,048
Ensembl chr 2:43,555,329...43,682,715
JBrowse link
aromatic amino acid family catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tat tyrosine aminotransferase IEA UniProt GO_REF:0000002, MGI:2152098 NCBI chr 8:109,986,078...109,999,804
Ensembl chr 8:109,990,437...109,999,803
JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase IBA
IDA
TAS
ISO
IMP
(MGI:6201960|PMID:21873635)
(MGI:2386819|PMID:9520487)
(MGI:1335713|PMID:10212311)
(MGI:72094|PMID:7715703), (MGI:77787|PMID:7592982)
GO_Central
MGI
PMID:7592982, PMID:7715703, PMID:9520487, PMID:10212311, PMID:21873635 GO_REF:0000096, MGI:1335713, MGI:2386819, MGI:4417868, MGI:6201960, MGI:72094, MGI:77787 NCBI chr 7:142,892,779...142,899,995
Ensembl chr 7:142,892,752...142,931,128
JBrowse link
L-phenylalanine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fah fumarylacetoacetate hydrolase IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 7:84,585,159...84,605,942
Ensembl chr 7:84,585,159...84,606,722
JBrowse link
G Gstz1 glutathione transferase zeta 1 (maleylacetoacetate isomerase) IBA
TAS
(MGI:6201960|PMID:21873635)
(MGI:1339892|PMID:10373324)
GO_Central
MGI
PMID:10373324, PMID:21873635 MGI:1339892, MGI:6201960 NCBI chr12:87,147,161...87,164,723
Ensembl chr12:87,147,165...87,164,723
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr16:37,579,742...37,632,026
Ensembl chr16:37,580,153...37,632,020
JBrowse link
G Hpd 4-hydroxyphenylpyruvic acid dioxygenase IEA UniProt GO_REF:0000004, MGI:1354194 NCBI chr 5:123,171,807...123,182,723
Ensembl chr 5:123,171,807...123,182,727
JBrowse link
G Pah phenylalanine hydroxylase IEA UniProt GO_REF:0000002, GO_REF:0000004, MGI:1354194, MGI:2152098 NCBI chr10:87,521,795...87,584,137
Ensembl chr10:87,521,795...87,584,136
JBrowse link
G Qdpr quinoid dihydropteridine reductase IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 5:45,434,032...45,450,229
Ensembl chr 5:45,434,021...45,450,236
JBrowse link
G Tat tyrosine aminotransferase IEA UniProt GO_REF:0000004, MGI:1354194 NCBI chr 8:109,986,078...109,999,804
Ensembl chr 8:109,990,437...109,999,803
JBrowse link
L-phenylalanine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase ISO MGI GO_REF:0000096, MGI:4417868 NCBI chr10:87,521,795...87,584,137
Ensembl chr10:87,521,795...87,584,136
JBrowse link
G Pcbd1 pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1 ISO MGI GO_REF:0000096, MGI:4417868 NCBI chr10:61,089,331...61,094,329
Ensembl chr10:61,089,331...61,094,324
JBrowse link
G Spr sepiapterin reductase IMP (MGI:3722569|PMID:16532389) MGI PMID:16532389 MGI:3722569 NCBI chr 6:85,133,680...85,137,764
Ensembl chr 6:85,130,176...85,137,766
JBrowse link
melanin biosynthetic process from tyrosine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dct dopachrome tautomerase IDA
IBA
(MGI:3690794|PMID:2169885)
(MGI:6201960|PMID:21873635)
UniProt
GO_Central
PMID:2169885, PMID:21873635 MGI:3690794, MGI:6201960 NCBI chr14:118,012,790...118,052,246
Ensembl chr14:118,012,790...118,052,244
JBrowse link
G Tyrp1 tyrosinase-related protein 1 TAS (MGI:3687692|PMID:9918801) UniProt PMID:9918801 MGI:3687692 NCBI chr 4:80,834,123...80,851,736
Ensembl chr 4:80,834,123...80,851,719
JBrowse link
positive regulation of L-dopa biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinson disease (autosomal recessive, early onset) 7 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 4:150,897,133...150,909,921
Ensembl chr 4:150,897,133...150,914,437
JBrowse link
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 ISO MGI GO_REF:0000096, MGI:4417868 NCBI chr15:82,370,527...82,380,260
Ensembl chr15:82,370,527...82,380,260
JBrowse link
G Tph2 tryptophan hydroxylase 2 IC (MGI:2652990|PMID:12584449) MGI PMID:12584449 MGI:2652990 NCBI chr10:115,078,641...115,185,022
Ensembl chr10:115,078,641...115,185,022
JBrowse link
tryptophan catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd amino carboxymuconate semialdehyde decarboxylase ISO MGI GO_REF:0000096, MGI:4417868 NCBI chr 1:127,729,413...127,767,564
Ensembl chr 1:127,729,413...127,767,978
JBrowse link
G Afmid arylformamidase IEA UniProt GO_REF:0000004, MGI:1354194 NCBI chr11:117,825,503...117,839,908
Ensembl chr11:117,825,924...117,839,908
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 IEA UniProt GO_REF:0000004, MGI:1354194 NCBI chr 8:24,584,133...24,596,952
Ensembl chr 8:24,584,136...24,597,009
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 IEA UniProt GO_REF:0000004, MGI:1354194 NCBI chr 8:24,531,892...24,576,414
Ensembl chr 8:24,531,892...24,576,333
JBrowse link
G Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) IEA UniProt GO_REF:0000002, MGI:2152098 NCBI chr 1:175,632,193...175,660,853
Ensembl chr 1:175,620,381...175,662,116
JBrowse link
G Kynu kynureninase ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 2:43,555,258...43,683,048
Ensembl chr 2:43,555,329...43,682,715
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase IEA UniProt GO_REF:0000004, MGI:1354194 NCBI chr 3:81,958,412...81,975,728
Ensembl chr 3:81,957,090...81,976,202
JBrowse link
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kynu kynureninase ISO MGI GO_REF:0000096, MGI:4417868 NCBI chr 2:43,555,258...43,683,048
Ensembl chr 2:43,555,329...43,682,715
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096, MGI:4417868, MGI:6201960 NCBI chr 3:81,958,412...81,975,728
Ensembl chr 3:81,957,090...81,976,202
JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase IDA
IBA
(MGI:3587527|PMID:15866519)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:15866519, PMID:21873635 MGI:3587527, MGI:6201960 NCBI chr11:117,825,503...117,839,908
Ensembl chr11:117,825,924...117,839,908
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 IBA
IDA
ISO
(MGI:6201960|PMID:21873635)
(MGI:2151782|PMID:2419335), (MGI:2156954|PMID:11751753)
GO_Central
MGI
PMID:2419335, PMID:11751753, PMID:21873635 GO_REF:0000096, MGI:2151782, MGI:2156954, MGI:4417868, MGI:6201960 NCBI chr 8:24,584,133...24,596,952
Ensembl chr 8:24,584,136...24,597,009
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 IBA
ISO
IDA
IMP
(MGI:6201960|PMID:21873635)
(MGI:3712725|PMID:17499941)
(MGI:3719924|PMID:17671174)
GO_Central
MGI
PMID:17499941, PMID:17671174, PMID:21873635 GO_REF:0000096, MGI:3712725, MGI:3719924, MGI:4834177, MGI:6201960 NCBI chr 8:24,531,892...24,576,414
Ensembl chr 8:24,531,892...24,576,333
JBrowse link
G Kynu kynureninase IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 2:43,555,258...43,683,048
Ensembl chr 2:43,555,329...43,682,715
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 3:81,958,412...81,975,728
Ensembl chr 3:81,957,090...81,976,202
JBrowse link
tryptophan metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase, Cu++ transporting, alpha polypeptide IMP (MGI:53851|PMID:4147174) MGI PMID:4147174 MGI:53851 NCBI chr  X:106,027,224...106,128,161
Ensembl chr  X:106,027,276...106,124,926
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase ISO MGI GO_REF:0000096, MGI:4417868 NCBI chr 3:81,958,412...81,975,728
Ensembl chr 3:81,957,090...81,976,202
JBrowse link
tyrosine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096, MGI:4417868, MGI:6201960 NCBI chr10:87,521,795...87,584,137
Ensembl chr10:87,521,795...87,584,136
JBrowse link
tyrosine biosynthetic process, by oxidation of phenylalanine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase ISO MGI GO_REF:0000096, MGI:4417868 NCBI chr10:87,521,795...87,584,137
Ensembl chr10:87,521,795...87,584,136
JBrowse link
tyrosine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fah fumarylacetoacetate hydrolase IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 7:84,585,159...84,605,942
Ensembl chr 7:84,585,159...84,606,722
JBrowse link
G Gstz1 glutathione transferase zeta 1 (maleylacetoacetate isomerase) TAS (MGI:1339892|PMID:10373324) MGI PMID:10373324 MGI:1339892 NCBI chr12:87,147,161...87,164,723
Ensembl chr12:87,147,165...87,164,723
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase IEA UniProt GO_REF:0000004, MGI:1354194 NCBI chr16:37,579,742...37,632,026
Ensembl chr16:37,580,153...37,632,020
JBrowse link
G Hpd 4-hydroxyphenylpyruvic acid dioxygenase IBA
ISO
(MGI:6201960|PMID:21873635)
(MGI:6362140|PMID:31537781)
GO_Central
MGI
PMID:21873635, PMID:31537781 GO_REF:0000096, MGI:4417868, MGI:6201960, MGI:6362140 NCBI chr 5:123,171,807...123,182,723
Ensembl chr 5:123,171,807...123,182,727
JBrowse link
G Tat tyrosine aminotransferase IDA
ISO
(MGI:5430853|PMID:21153519) UniProt
MGI
PMID:21153519 GO_REF:0000096, MGI:4834177, MGI:5430853 NCBI chr 8:109,986,078...109,999,804
Ensembl chr 8:109,990,437...109,999,803
JBrowse link
tyrosine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase, Cu++ transporting, alpha polypeptide IMP (MGI:53851|PMID:4147174) MGI PMID:4147174 MGI:53851 NCBI chr  X:106,027,224...106,128,161
Ensembl chr  X:106,027,276...106,124,926
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase IEA UniProt GO_REF:0000002, MGI:2152098 NCBI chr16:37,579,742...37,632,026
Ensembl chr16:37,580,153...37,632,020
JBrowse link
G Iyd iodotyrosine deiodinase IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096, MGI:4834177, MGI:6201960 NCBI chr10:3,540,274...3,554,880
Ensembl chr10:3,540,240...3,554,877
JBrowse link
G Thap4 THAP domain containing 4 ISO MGI GO_REF:0000096, MGI:4834177 NCBI chr 1:93,705,391...93,754,838
Ensembl chr 1:93,701,935...93,754,864
JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 IMP (MGI:6362140|PMID:31537781) MGI PMID:31537781 MGI:6362140 NCBI chr 9:44,799,400...44,802,951
Ensembl chr 9:44,799,397...44,803,072
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23386
    metabolic process 11305
      cellular metabolic process 10088
        organic acid metabolic process 956
          aromatic amino acid family metabolic process 30
            L-dopa metabolic process + 1
            L-phenylalanine metabolic process + 9
            anthranilate metabolic process + 1
            aromatic amino acid family biosynthetic process + 2
            aromatic amino acid family catabolic process + 14
            gliotoxin biosynthetic process + 0
            para-aminobenzoic acid metabolic process + 0
            tryptophan metabolic process + 11
            tyrosine metabolic process + 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.