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ONTOLOGY REPORT - ANNOTATIONS

Term:serine family amino acid biosynthetic process
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Accession:GO:0009070 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.
Synonyms:exact_synonym: serine family amino acid anabolism;   serine family amino acid biosynthesis;   serine family amino acid formation;   serine family amino acid synthesis


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serine family amino acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IMP (PMID:25633902) BHF-UCL PMID:25633902 NCBI chr14:64,388,353...64,460,025
Ensembl chr14:64,388,031...64,463,457 		JBrowse link
cysteine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBS cystathionine beta-synthase involved_in
acts_upstream_of_or_within		 IDA
ISO
IEA		 (PMID:24416422)
(PMID:15030387)		 BHF-UCL
MGI
Ensembl
UniProt		 PMID:15030387 PMID:24416422 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr21:43,053,191...43,076,873
Ensembl chr21:43,053,191...43,076,943 		JBrowse link
G CBSL cystathionine beta-synthase like involved_in IEA
IDA		 (PMID:24416422) UniProt
BHF-UCL
Ensembl		 PMID:24416422 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr21:6,444,869...6,468,621
Ensembl chr21:43,053,191...43,076,943 		JBrowse link
G CTH cystathionine gamma-lyase involved_in IEA
IDA		 (PMID:10212249) UniProt PMID:10212249 GO_REF:0000041 GO_REF:0000043 NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005 		JBrowse link
cysteine biosynthetic process from serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBS cystathionine beta-synthase involved_in IEA
IBA		 UniProt
GO_Central
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118 NCBI chr21:43,053,191...43,076,873
Ensembl chr21:43,053,191...43,076,943 		JBrowse link
G CBSL cystathionine beta-synthase like involved_in IEA
IBA		 InterPro
GO_Central
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118 NCBI chr21:6,444,869...6,468,621
Ensembl chr21:43,053,191...43,076,943 		JBrowse link
cysteine biosynthetic process via cystathionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBS cystathionine beta-synthase involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr21:43,053,191...43,076,873
Ensembl chr21:43,053,191...43,076,943 		JBrowse link
G CBSL cystathionine beta-synthase like involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr21:6,444,869...6,468,621
Ensembl chr21:43,053,191...43,076,943 		JBrowse link
G CTH cystathionine gamma-lyase involved_in IDA
IBA		 (PMID:19428278) BHF-UCL
GO_Central		 PMID:19428278 GO_REF:0000033 NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851 		JBrowse link
glycine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAO1 hydroxyacid oxidase 1 involved_in IEA UniProt GO_REF:0000041 NCBI chr20:7,882,985...7,940,458
Ensembl chr20:7,882,985...7,940,458 		JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 ISO from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr17:18,327,873...18,363,550
Ensembl chr17:18,327,873...18,363,550 		JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in ISO
IEA		 from L-allothreonine in the absence of tetrahydrofolate RGD
Ensembl		 PMID:3110140 GO_REF:0000107 RGD:2300383 NCBI chr12:57,229,711...57,234,935
Ensembl chr12:57,229,573...57,234,935 		JBrowse link
glycine biosynthetic process from serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SHMT1 serine hydroxymethyltransferase 1 involved_in ISO
IEA
IBA		 in the presence of tetrahydrofolate RGD
TreeGrafter
GO_Central
InterPro		 PMID:3110140 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 RGD:2300383 NCBI chr17:18,327,873...18,363,550
Ensembl chr17:18,327,873...18,363,550 		JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in ISO
IBA
IEA		 in the presence of tetrahydrofolate RGD
GO_Central
TreeGrafter
Ensembl
InterPro		 PMID:3110140 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:2300383 NCBI chr12:57,229,711...57,234,935
Ensembl chr12:57,229,573...57,234,935 		JBrowse link
glycine biosynthetic process, by transamination of glyoxylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGXT alanine--glyoxylate aminotransferase involved_in ISO
IEA
IBA
IDA		 (PMID:22198249) RGD
TreeGrafter
GO_Central
UniProt		 PMID:12383475 PMID:22198249 GO_REF:0000033 GO_REF:0000118 RGD:1599457 NCBI chr 2:240,868,824...240,880,500
Ensembl chr 2:240,868,824...240,880,502 		JBrowse link
G AGXT2 alanine--glyoxylate aminotransferase 2 involved_in IDA (PMID:20018850) BHF-UCL PMID:20018850 NCBI chr 5:34,998,102...35,047,949
Ensembl chr 5:34,998,101...35,048,135 		JBrowse link
L-serine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PHGDH phosphoglycerate dehydrogenase involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:119,711,934...119,744,215
Ensembl chr 1:119,648,411...119,744,218 		JBrowse link
G PSAT1 phosphoserine aminotransferase 1 involved_in IEA
IBA
IDA
NAS		 (PMID:37627284)
(PMID:10637769)		 InterPro
GO_Central
TreeGrafter
UniProt		 PMID:10637769 PMID:37627284 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 9:78,297,125...78,330,093
Ensembl chr 9:78,297,125...78,330,093 		JBrowse link
G PSPH phosphoserine phosphatase involved_in IEA
IBA
IMP		 (PMID:14673469) UniProt
GO_Central
TreeGrafter
InterPro		 PMID:14673469 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 7:56,011,064...56,051,444
Ensembl chr 7:56,011,051...56,051,604 		JBrowse link
G SERINC3 serine incorporator 3 involved_in TAS Reactome Reactome:R-HSA-977347 NCBI chr20:44,496,221...44,522,070
Ensembl chr20:44,496,221...44,522,085 		JBrowse link
G SERINC5 serine incorporator 5 involved_in TAS Reactome Reactome:R-HSA-977347 NCBI chr 5:80,111,225...80,256,048
Ensembl chr 5:80,111,651...80,256,048 		JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:10457370 GO_REF:0000107 RGD:2300380 NCBI chr12:57,229,711...57,234,935
Ensembl chr12:57,229,573...57,234,935 		JBrowse link
selenocysteine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SEPHS1 selenophosphate synthetase 1 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr10:13,317,428...13,348,293
Ensembl chr10:13,317,428...13,348,298 		JBrowse link
G SEPHS2 selenophosphate synthetase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
NAS		 (PMID:17346238)
(PMID:8986768)		 Ensembl
MGI
GO_Central
TreeGrafter
UniProt		 PMID:8986768 PMID:17346238 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr16:30,443,631...30,445,874
Ensembl chr16:30,443,631...30,445,874 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    metabolic process 12464
      primary metabolic process 10695
        amino acid metabolic process 316
          proteinogenic amino acid metabolic process 179
            serine family amino acid metabolic process 40
              serine family amino acid biosynthetic process 17
                L-homocysteine biosynthetic process 0
                L-serine biosynthetic process 6
                cysteine biosynthetic process + 4
                glycine biosynthetic process + 5
                homoserine biosynthetic process + 0
                selenocysteine biosynthetic process 2
Path 2
Term Annotations click to browse term
  biological_process 19669
    cellular process 18300
      cellular metabolic process 10651
        organic acid metabolic process 1051
          oxoacid metabolic process 1042
            carboxylic acid metabolic process 1017
              alpha-amino acid metabolic process 231
                L-amino acid metabolic process 190
                  serine family amino acid metabolic process 40
                    serine family amino acid biosynthetic process 17
                      L-homocysteine biosynthetic process 0
                      L-serine biosynthetic process 6
                      cysteine biosynthetic process + 4
                      glycine biosynthetic process + 5
                      homoserine biosynthetic process + 0
                      selenocysteine biosynthetic process 2
paths to the root