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ONTOLOGY REPORT - ANNOTATIONS

Term:serine family amino acid biosynthetic process
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Accession:GO:0009070 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.
Synonyms:exact_synonym: serine family amino acid anabolism;   serine family amino acid biosynthesis;   serine family amino acid formation;   serine family amino acid synthesis


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serine family amino acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:44,969,573...45,041,296
Ensembl chr14:63,223,484...63,293,881 		JBrowse link
cysteine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBS cystathionine beta-synthase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15030387) UniProt
MGI
Ensembl		 PMID:15030387 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr21:29,361,519...29,385,610
Ensembl chr21:42,670,530...42,690,932 		JBrowse link
G CTH cystathionine gamma-lyase involved_in IEA UniProt
Ensembl		 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr 1:69,646,608...69,674,301
Ensembl chr 1:71,629,333...71,677,666 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 involved_in ISO (MGI:5294309|PMID:12468440) UniProt PMID:12468440 MGI:5294309 NCBI chr22:5,424,334...5,469,705 JBrowse link
cysteine biosynthetic process from serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBS cystathionine beta-synthase involved_in IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr21:29,361,519...29,385,610
Ensembl chr21:42,670,530...42,690,932 		JBrowse link
cysteine biosynthetic process via cystathionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBS cystathionine beta-synthase involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr21:29,361,519...29,385,610
Ensembl chr21:42,670,530...42,690,932 		JBrowse link
G CTH cystathionine gamma-lyase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:69,646,608...69,674,301
Ensembl chr 1:71,629,333...71,677,666 		JBrowse link
glycine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHFR dihydrofolate reductase involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:34,663,210...34,689,467
Ensembl chr 5:34,938,548...34,967,003 		JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 ISO from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr17:32,870,949...32,905,690
Ensembl chr17:37,849,206...37,884,220 		JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 ISO from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr12:31,692,451...31,697,727
Ensembl chr12:31,944,785...31,950,138 		JBrowse link
glycine biosynthetic process from serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SHMT1 serine hydroxymethyltransferase 1 involved_in ISO
IEA		 in the presence of tetrahydrofolate RGD
TreeGrafter
InterPro		 PMID:3110140 GO_REF:0000002 GO_REF:0000118 RGD:2300383 NCBI chr17:32,870,949...32,905,690
Ensembl chr17:37,849,206...37,884,220 		JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in ISO
IEA		 in the presence of tetrahydrofolate RGD
TreeGrafter
InterPro		 PMID:3110140 GO_REF:0000002 GO_REF:0000118 RGD:2300383 NCBI chr12:31,692,451...31,697,727
Ensembl chr12:31,944,785...31,950,138 		JBrowse link
glycine biosynthetic process, by transamination of glyoxylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGXT alanine--glyoxylate aminotransferase involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:12383475 GO_REF:0000107 GO_REF:0000118 RGD:1599457 NCBI chr2B:128,125,289...128,137,091
Ensembl chr2B:246,928,784...246,939,837 		JBrowse link
G AGXT2 alanine--glyoxylate aminotransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:75,322,351...75,373,261
Ensembl chr 5:80,601,554...80,652,575 		JBrowse link
L-serine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100993185 putative phosphoserine phosphatase-like protein involved_in ISO (PMID:14673469) UniProt PMID:14673469 NCBI chr 7:56,351,434...56,376,714 JBrowse link
G PHGDH phosphoglycerate dehydrogenase involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:82,803,155...82,835,465
Ensembl chr 1:117,800,843...117,833,462 		JBrowse link
G PSAT1 phosphoserine aminotransferase 1 involved_in IEA UniProt
TreeGrafter
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:46,517,253...46,550,018
Ensembl chr 9:77,147,493...77,180,439 		JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 ISO RGD PMID:10457370 RGD:2300380 NCBI chr12:31,692,451...31,697,727
Ensembl chr12:31,944,785...31,950,138 		JBrowse link
selenocysteine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100970229 selenide, water dikinase 2-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:170,058,006...170,060,257 JBrowse link
G SEPHS1 selenophosphate synthetase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:13,316,013...13,347,087
Ensembl chr10:13,649,672...13,679,724 		JBrowse link
G SEPHS2 selenophosphate synthetase 2 acts_upstream_of_or_within ISO (PMID:17346238) MGI PMID:17346238 NCBI chr16:24,523,111...24,525,390 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    metabolic process 10179
      primary metabolic process 8792
        amino acid metabolic process 285
          proteinogenic amino acid metabolic process 163
            serine family amino acid metabolic process 37
              serine family amino acid biosynthetic process 15
                L-homocysteine biosynthetic process 0
                L-serine biosynthetic process 4
                cysteine biosynthetic process + 3
                glycine biosynthetic process + 5
                homoserine biosynthetic process + 0
                selenocysteine biosynthetic process 3
Path 2
Term Annotations click to browse term
  biological_process 16313
    cellular process 15397
      cellular metabolic process 8945
        organic acid metabolic process 899
          oxoacid metabolic process 892
            carboxylic acid metabolic process 870
              alpha-amino acid metabolic process 208
                L-amino acid metabolic process 173
                  serine family amino acid metabolic process 37
                    serine family amino acid biosynthetic process 15
                      L-homocysteine biosynthetic process 0
                      L-serine biosynthetic process 4
                      cysteine biosynthetic process + 3
                      glycine biosynthetic process + 5
                      homoserine biosynthetic process + 0
                      selenocysteine biosynthetic process 3
paths to the root