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ONTOLOGY REPORT - ANNOTATIONS


Term:serine family amino acid biosynthetic process
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Accession:GO:0009070 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.
Synonyms:exact_synonym: serine family amino acid anabolism;   serine family amino acid biosynthesis;   serine family amino acid formation;   serine family amino acid synthesis



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serine family amino acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) RGD PMID:25633902 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link
G Phgdh phosphoglycerate dehydrogenase TAS RGD PMID:9163325 RGD:61693 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
cysteine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:24416422)
PMID:21873635
MGI:1857139 (MGI:3044255|PMID:15030387)
RGD PMID:15030387 PMID:24416422 PMID:21873635 MGI:3044255, RGD:13792537 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Cth cystathionine gamma-lyase involved_in IDA
ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000041
(PMID:10212249)
UniProt
RGD
PMID:10212249 PMID:9359866 GO_REF:0000024 GO_REF:0000041, RGD:1359024 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 involved_in ISO
IEA
(MGI:5294309|PMID:12468440)
GO_REF:0000107
RGD
Ensembl
PMID:12468440 GO_REF:0000107 MGI:5294309 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
cysteine biosynthetic process from serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase TAS RGD PMID:9359866 RGD:1359024 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
cysteine biosynthetic process via cystathionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Cth cystathionine gamma-lyase involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:19428278)
Ensembl
RGD
PMID:19428278 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
D-serine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srr serine racemase involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:11054547), (PMID:15193426)
PMID:21873635
(MGI:1347751|PMID:10557334), (MGI:1926659|PMID:11054547), (MGI:2183617|PMID:12021263), (MGI:3529732|PMID:15710237)
RGD PMID:10557334 PMID:11054547 PMID:12021263 PMID:15193426 PMID:15710237 More... MGI:1347751 MGI:1926659 MGI:2183617 MGI:3529732, RGD:13792537 NCBI chr10:59,769,563...59,786,688
Ensembl chr10:59,769,571...59,787,011
JBrowse link
glycine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhfr dihydrofolate reductase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G LOC688286 similar to threonine aldolase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:103,094,681...103,100,169
Ensembl chr10:103,094,681...103,100,519
JBrowse link
G Sardh sarcosine dehydrogenase TAS RGD PMID:9839943 RGD:634034 NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 IDA from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 IDA from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
glycine biosynthetic process from serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shmt1 serine hydroxymethyltransferase 1 involved_in IDA
IBA
in the presence of tetrahydrofolate
PMID:21873635
RGD
GO_Central
PMID:3110140 PMID:21873635 RGD:2300383, RGD:13792537 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in IDA
IBA
in the presence of tetrahydrofolate
PMID:21873635
RGD
GO_Central
PMID:3110140 PMID:21873635 RGD:2300383, RGD:13792537 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
glycine biosynthetic process, by transamination of glyoxylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase involved_in IDA
ISO
IBA
(PMID:22198249)
PMID:21873635
RGD PMID:22198249 PMID:12383475 PMID:21873635 RGD:1599457, RGD:13792537 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 involved_in ISO (PMID:20018850) RGD PMID:20018850 NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926
JBrowse link
L-serine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phgdh phosphoglycerate dehydrogenase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Psat1 phosphoserine aminotransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Psph phosphoserine phosphatase involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:14673469)
UniProt
RGD
PMID:14673469 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr12:26,882,524...26,905,084
Ensembl chr12:26,883,133...26,905,074
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 IDA RGD PMID:10457370 RGD:2300380 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
selenocysteine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sephs1 selenophosphate synthetase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:73,354,435...73,382,803
Ensembl chr17:73,356,530...73,382,593
JBrowse link
G Sephs2 selenophosphate synthetase 2 acts_upstream_of_or_within ISO (MGI:3711593|PMID:17346238) RGD PMID:17346238 MGI:3711593 NCBI chr 1:181,893,146...181,895,464
Ensembl chr 1:181,892,599...181,895,497
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      primary metabolic process 10535
        cellular amino acid metabolic process 277
          cellular amino acid biosynthetic process 72
            alpha-amino acid biosynthetic process 66
              serine family amino acid biosynthetic process 17
                D-serine biosynthetic process 1
                L-homocysteine biosynthetic process 0
                L-serine biosynthetic process 4
                cysteine biosynthetic process + 3
                glycine biosynthetic process + 7
                homoserine biosynthetic process + 0
                selenocysteine biosynthetic process 2
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      cellular metabolic process 10719
        organic acid metabolic process 1013
          oxoacid metabolic process 982
            carboxylic acid metabolic process 961
              carboxylic acid biosynthetic process 295
                cellular amino acid biosynthetic process 72
                  alpha-amino acid biosynthetic process 66
                    serine family amino acid biosynthetic process 17
                      D-serine biosynthetic process 1
                      L-homocysteine biosynthetic process 0
                      L-serine biosynthetic process 4
                      cysteine biosynthetic process + 3
                      glycine biosynthetic process + 7
                      homoserine biosynthetic process + 0
                      selenocysteine biosynthetic process 2
paths to the root