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ONTOLOGY REPORT - ANNOTATIONS

Term:aspartate family amino acid biosynthetic process
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Accession:GO:0009067 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
Synonyms:exact_synonym: aspartate family amino acid anabolism;   aspartate family amino acid biosynthesis;   aspartate family amino acid formation;   aspartate family amino acid synthesis


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asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) acts_upstream_of_or_within
involved_in		 IDA
ISO
IBA		 (PMID:2573597)
PMID:21873635		 RGD PMID:2573597 PMID:2887559 PMID:21873635 RGD:2316002, RGD:13792537 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Asnsd1 asparagine synthetase domain containing 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:48,126,802...48,139,073
Ensembl chr 9:48,126,808...48,139,073 		JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:53641|PMID:4193185)		 RGD PMID:4193185 PMID:21873635 MGI:53641, RGD:13792537 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:64,860,308...64,873,656
Ensembl chr16:64,860,704...64,866,162 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) RGD PMID:4193185 MGI:53641 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 involved_in ISO
IEA		 (PMID:10934207)
GO_REF:0000107		 RGD
Ensembl		 PMID:10934207 GO_REF:0000107 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 involved_in ISO (MGI:6202004|PMID:16447251) RGD PMID:16447251 MGI:6202004 NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960 		JBrowse link
L-asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IEA		 (PMID:18230605)
GO_REF:0000107		 RGD
Ensembl		 PMID:18230605 GO_REF:0000107 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18230605)		 Ensembl
RGD		 PMID:18230605 GO_REF:0000107 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475 		JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IEA
ISS
ISO		 GO_REF:0000041
GO_REF:0000024
(PMID:15938715)		 UniProt
RGD		 PMID:15938715 GO_REF:0000024 GO_REF:0000041 NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842 		JBrowse link
G Apip APAF1 interacting protein involved_in IEA
IBA
ISO		 GO_REF:0000041
PMID:21873635
(PMID:22837397), (PMID:23285211)		 UniProt
RGD		 PMID:22837397 PMID:23285211 PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 3:89,431,973...89,457,999
Ensembl chr 3:89,432,037...89,458,340 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA
ISO
IBA
ISS		 GO_REF:0000041
(PMID:15843022)
PMID:21873635
GO_REF:0000024		 UniProt
RGD		 PMID:15843022 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IBA
IEA		 PMID:21873635
GO_REF:0000041		 UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr19:23,907,335...23,913,320
Ensembl chr19:23,907,335...23,913,320 		JBrowse link
G Mtap methylthioadenosine phosphorylase involved_in IBA
IEA		 PMID:21873635
GO_REF:0000041		 UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 5:103,873,020...103,939,406
Ensembl chr 5:103,873,020...103,939,406 		JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:89,431,973...89,457,999
Ensembl chr 3:89,432,037...89,458,340 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr19:23,907,335...23,913,320
Ensembl chr19:23,907,335...23,913,320 		JBrowse link
lysine biosynthetic process via aminoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:1,453,226...1,463,990
Ensembl chr 8:1,452,282...1,463,966 		JBrowse link
G Aass aminoadipate-semialdehyde synthase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136 		JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase acts_upstream_of_or_within IDA
ISO		 (MGI:3510291|PMID:15217352) RGD PMID:15217352 PMID:15845641 MGI:3510291, RGD:1359026 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) RGD PMID:25633902 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:2385823 (MGI:3510291|PMID:15217352)		 RGD PMID:15217352 PMID:21873635 MGI:3510291, RGD:13792537 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO		 GO_REF:0000117
MGI:2180496 (MGI:1930456|PMID:11158293)
(PMID:23825108)		 UniProt
RGD		 PMID:11158293 PMID:23825108 PMID:15845641 PMID:11730351 GO_REF:0000117 MGI:1930456, RGD:1359026, RGD:1601423 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO
IBA		 (PMID:11466310)
(MGI:3710265|PMID:17369066)
PMID:21873635		 RGD PMID:11466310 PMID:17369066 PMID:21873635 MGI:3710265, RGD:13792537 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thnsl2 threonine synthase-like 2 NOT|acts_upstream_of_or_within ISO (MGI:3690523|PMID:17034760) RGD PMID:17034760 MGI:3690523 NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    metabolic process 11791
      primary metabolic process 10525
        cellular amino acid metabolic process 276
          cellular amino acid biosynthetic process 72
            alpha-amino acid biosynthetic process 66
              aspartate family amino acid biosynthetic process 22
                L-isoleucine biosynthetic process 0
                asparagine biosynthetic process + 2
                aspartate biosynthetic process 3
                hydroxylysine biosynthetic process 2
                lysine biosynthetic process + 2
                methionine biosynthetic process + 12
                threonine biosynthetic process 1
Path 2
Term Annotations click to browse term
  biological_process 19512
    metabolic process 11791
      cellular metabolic process 10675
        organic acid metabolic process 1009
          oxoacid metabolic process 978
            carboxylic acid metabolic process 962
              carboxylic acid biosynthetic process 296
                cellular amino acid biosynthetic process 72
                  alpha-amino acid biosynthetic process 66
                    aspartate family amino acid biosynthetic process 22
                      L-isoleucine biosynthetic process 0
                      asparagine biosynthetic process + 2
                      aspartate biosynthetic process 3
                      hydroxylysine biosynthetic process 2
                      lysine biosynthetic process + 2
                      methionine biosynthetic process + 12
                      threonine biosynthetic process 1
paths to the root