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ONTOLOGY REPORT - ANNOTATIONS

Term:aspartate family amino acid biosynthetic process
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Accession:GO:0009067 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
Synonyms:exact_synonym: aspartate family amino acid anabolism;   aspartate family amino acid biosynthesis;   aspartate family amino acid formation;   aspartate family amino acid synthesis


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'de novo' L-methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IEA		 (PMID:10529246)
GO_REF:0000107		 RGD
Ensembl		 PMID:10529246 GO_REF:0000107 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) involved_in
acts_upstream_of_or_within		 IDA
IBA
ISO		 GO_REF:0000033
(PMID:2573597)		 GO_Central
RGD		 PMID:2573597 PMID:2887559 GO_REF:0000033, RGD:2316002 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Asnsd1 asparagine synthetase domain containing 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:48,126,808...48,139,073
Ensembl chr 9:48,126,808...48,139,073 		JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
(PMID:4193185)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:4193185 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:64,860,308...64,873,656
Ensembl chr16:64,860,704...64,866,162 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (PMID:4193185) RGD PMID:4193185 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 involved_in ISO
IEA		 (PMID:10934207)
GO_REF:0000107		 RGD
Ensembl		 PMID:10934207 GO_REF:0000107 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 involved_in ISO
IEA		 (MGI:6202004|PMID:16447251)
GO_REF:0000107		 RGD
Ensembl		 PMID:16447251 GO_REF:0000107 MGI:6202004 NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960 		JBrowse link
L-asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IEA
IBA		 (PMID:18230605)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:18230605 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in IEA
ISO
IBA		 GO_REF:0000107
(PMID:18230605)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:18230605 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475 		JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IEA
ISS
ISO		 GO_REF:0000041
GO_REF:0000024
(PMID:15938715)		 UniProt
RGD		 PMID:15938715 GO_REF:0000024 GO_REF:0000041 NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842 		JBrowse link
G Apip APAF1 interacting protein involved_in IEA
IBA
ISO		 GO_REF:0000041
GO_REF:0000033
(PMID:22837397), (PMID:23285211)		 UniProt
GO_Central
RGD		 PMID:22837397 PMID:23285211 GO_REF:0000033 GO_REF:0000041 NCBI chr 3:89,431,964...89,458,000
Ensembl chr 3:89,432,037...89,458,340 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA
IBA
ISO
ISS		 GO_REF:0000041
GO_REF:0000033
(PMID:15843022)
GO_REF:0000024		 UniProt
GO_Central
RGD		 PMID:15843022 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA
IBA		 GO_REF:0000041
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 NCBI chr19:23,907,327...23,913,721
Ensembl chr19:23,907,335...23,913,320 		JBrowse link
G Mtap methylthioadenosine phosphorylase involved_in IEA
IBA		 GO_REF:0000041
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 NCBI chr 5:103,874,460...103,920,684
Ensembl chr 5:103,873,020...103,939,406 		JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:89,431,964...89,458,000
Ensembl chr 3:89,432,037...89,458,340 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr19:23,907,327...23,913,721
Ensembl chr19:23,907,335...23,913,320 		JBrowse link
lysine biosynthetic process via aminoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:1,453,226...1,463,990
Ensembl chr 8:1,452,282...1,463,966 		JBrowse link
G Aass aminoadipate-semialdehyde synthase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136 		JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase acts_upstream_of_or_within IDA
ISO		 (PMID:15217352) RGD PMID:15217352 PMID:15845641 RGD:1359026 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO
IEA		 (PMID:25633902)
GO_REF:0000107		 RGD
Ensembl		 PMID:25633902 GO_REF:0000107 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2385823 (PMID:15217352)		 GO_Central
RGD		 PMID:15217352 GO_REF:0000033 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase acts_upstream_of_or_within
involved_in		 IDA
ISO
IBA		 MGI:2180496 (PMID:11158293)
PMID:20424322
GO_REF:0000033
(PMID:23825108)		 RGD
GO_Central		 PMID:11158293 PMID:23825108 PMID:15845641 PMID:20424322 PMID:11730351 GO_REF:0000033, RGD:1359026, RGD:10054082, RGD:1601423 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO
IBA
IEA		 (PMID:11466310)
GO_REF:0000033
GO_REF:0000043
(MGI:3710265|PMID:17369066)		 RGD
GO_Central
UniProt		 PMID:11466310 PMID:17369066 GO_REF:0000033 GO_REF:0000043 MGI:3710265 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thnsl2 threonine synthase-like 2 NOT|acts_upstream_of_or_within ISO (PMID:17034760) RGD PMID:17034760 NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12289
      biosynthetic process 8419
        amino acid biosynthetic process 79
          alpha-amino acid biosynthetic process 70
            L-amino acid biosynthetic process 64
              aspartate family amino acid biosynthetic process 22
                L-isoleucine biosynthetic process 0
                asparagine biosynthetic process + 2
                aspartate biosynthetic process 3
                hydroxylysine biosynthetic process 2
                lysine biosynthetic process + 2
                methionine biosynthetic process + 12
                threonine biosynthetic process 1
Path 2
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12289
      cellular metabolic process 10294
        organic acid metabolic process 1033
          oxoacid metabolic process 1022
            carboxylic acid metabolic process 1007
              carboxylic acid biosynthetic process 326
                alpha-amino acid biosynthetic process 70
                  L-amino acid biosynthetic process 64
                    aspartate family amino acid biosynthetic process 22
                      L-isoleucine biosynthetic process 0
                      asparagine biosynthetic process + 2
                      aspartate biosynthetic process 3
                      hydroxylysine biosynthetic process 2
                      lysine biosynthetic process + 2
                      methionine biosynthetic process + 12
                      threonine biosynthetic process 1
paths to the root