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ONTOLOGY REPORT - ANNOTATIONS


Term:aspartate family amino acid biosynthetic process
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Accession:GO:0009067 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
Synonyms:exact_synonym: aspartate family amino acid anabolism;   aspartate family amino acid biosynthesis;   aspartate family amino acid formation;   aspartate family amino acid synthesis


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asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) IDA
IBA
ISO
PMID:21873635
(PMID:2573597)
RGD PMID:2573597, PMID:2887559, PMID:21873635 RGD:2316002, RGD:13792537 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Asnsd1 asparagine synthetase domain containing 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:52,988,042...53,009,054
Ensembl chr 9:53,004,499...53,009,054
JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 ISO
IBA
(MGI:53641|PMID:4193185)
PMID:21873635
RGD PMID:4193185, PMID:21873635 MGI:53641, RGD:13792537 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:69,022,756...69,035,507
Ensembl chr16:69,022,784...69,028,179
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 ISO (MGI:53641|PMID:4193185) RGD PMID:4193185 MGI:53641 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 IEA
ISO
GO_REF:0000107
(PMID:10934207)
Ensembl
RGD
PMID:10934207 GO_REF:0000107 NCBI chr 8:99,977,334...100,059,736
Ensembl chr 8:99,977,334...100,059,736
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 ISO (MGI:6202004|PMID:16447251) RGD PMID:16447251 MGI:6202004 NCBI chr12:22,716,421...22,726,982
Ensembl chr12:22,716,423...22,726,982
JBrowse link
L-asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase ISO
IEA
(PMID:18230605)
GO_REF:0000107
RGD
Ensembl
PMID:18230605 GO_REF:0000107 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 ISO
IEA
(PMID:18230605)
GO_REF:0000107
RGD
Ensembl
PMID:18230605 GO_REF:0000107 NCBI chr 2:23,272,320...23,289,266
Ensembl chr 2:23,272,328...23,289,266
JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 IEA
ISS
ISO
GO_REF:0000041
GO_REF:0000024
(PMID:15938715)
UniProt
RGD
PMID:15938715 GO_REF:0000024, GO_REF:0000041 NCBI chr 6:47,940,211...47,947,173
Ensembl chr 6:47,940,183...47,947,230
JBrowse link
G Apip APAF1 interacting protein IEA
IBA
ISO
GO_REF:0000041
PMID:21873635
(PMID:22837397), (PMID:23285211)
UniProt
RGD
PMID:22837397, PMID:23285211, PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 3:92,969,128...92,998,104
Ensembl chr 3:92,969,141...92,995,483
JBrowse link
G Enoph1 enolase-phosphatase 1 IEA
IBA
ISS
ISO
GO_REF:0000041
PMID:21873635
GO_REF:0000024
(PMID:15843022)
UniProt
RGD
PMID:15843022, PMID:21873635 GO_REF:0000024, GO_REF:0000041, RGD:13792537 NCBI chr14:11,172,359...11,198,799
Ensembl chr14:11,172,362...11,198,194
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr19:25,360,299...25,366,283
Ensembl chr19:25,360,164...25,366,806
JBrowse link
G Mtap methylthioadenosine phosphorylase IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 5:107,711,077...107,777,530
Ensembl chr 5:107,711,077...107,777,530
JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:92,969,128...92,998,104
Ensembl chr 3:92,969,141...92,995,483
JBrowse link
G Enoph1 enolase-phosphatase 1 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:11,172,359...11,198,799
Ensembl chr14:11,172,362...11,198,194
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr19:25,360,299...25,366,283
Ensembl chr19:25,360,164...25,366,806
JBrowse link
lysine biosynthetic process via aminoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:1,432,757...1,450,175
Ensembl chr 8:1,439,340...1,450,138
JBrowse link
G Aass aminoadipate-semialdehyde synthase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:50,152,005...50,208,935
Ensembl chr 4:50,152,452...50,200,328
JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase IDA
ISO
(MGI:3510291|PMID:15217352) RGD PMID:15217352, PMID:15845641 MGI:3510291, RGD:1359026 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO (PMID:25633902) RGD PMID:25633902 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:18,640,274...18,721,298
Ensembl chr14:18,640,277...18,720,357
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO
IBA
MGI:2385823 (MGI:3510291|PMID:15217352)
PMID:21873635
RGD PMID:15217352, PMID:21873635 MGI:3510291, RGD:13792537 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase IDA
ISO
IEA
MGI:2180496 (MGI:1930456|PMID:11158293)
GO_REF:0000107
(PMID:23825108)
RGD
Ensembl
PMID:11158293, PMID:23825108, PMID:15845641, PMID:11730351 GO_REF:0000107, MGI:1930456, RGD:1359026, RGD:1601423 NCBI chr17:66,210,444...66,295,014
Ensembl chr17:66,210,461...66,295,014
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO
IBA
(PMID:11466310)
PMID:21873635
(MGI:3710265|PMID:17369066)
RGD PMID:11466310, PMID:17369066, PMID:21873635 MGI:3710265, RGD:13792537 NCBI chr 1:37,743,089...37,774,485
Ensembl chr 1:37,743,147...37,774,015
JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thnsl2 threonine synthase-like 2 NOT ISO (MGI:3690523|PMID:17034760) RGD PMID:17034760 MGI:3690523 NCBI chr 4:98,976,559...98,997,187
Ensembl chr 4:98,976,550...98,995,590
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20030
    metabolic process 12185
      nitrogen compound metabolic process 10212
        organonitrogen compound metabolic process 6949
          organonitrogen compound biosynthetic process 2023
            alpha-amino acid biosynthetic process 64
              aspartate family amino acid biosynthetic process 22
                L-isoleucine biosynthetic process 0
                asparagine biosynthetic process + 2
                aspartate biosynthetic process 3
                hydroxylysine biosynthetic process 2
                lysine biosynthetic process + 2
                methionine biosynthetic process + 12
                threonine biosynthetic process 1
Path 2
Term Annotations click to browse term
  biological_process 20030
    metabolic process 12185
      cellular metabolic process 10964
        organic acid metabolic process 1007
          oxoacid metabolic process 969
            carboxylic acid metabolic process 950
              cellular amino acid metabolic process 268
                alpha-amino acid metabolic process 190
                  alpha-amino acid biosynthetic process 64
                    aspartate family amino acid biosynthetic process 22
                      L-isoleucine biosynthetic process 0
                      asparagine biosynthetic process + 2
                      aspartate biosynthetic process 3
                      hydroxylysine biosynthetic process 2
                      lysine biosynthetic process + 2
                      methionine biosynthetic process + 12
                      threonine biosynthetic process 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.