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ONTOLOGY REPORT - ANNOTATIONS

Term:aspartate family amino acid biosynthetic process
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Accession:GO:0009067 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
Synonyms:exact_synonym: aspartate family amino acid anabolism;   aspartate family amino acid biosynthesis;   aspartate family amino acid formation;   aspartate family amino acid synthesis


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asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) involved_in
acts_upstream_of_or_within 		IDA
IEA
IBA
ISO 		GO_REF:0000002
GO_REF:0000043
GO_REF:0000033
(PMID:2573597) 		InterPro
UniProt
GO_Central
RGD		 PMID:2573597 PMID:2887559 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043, RGD:2316002 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050 		JBrowse link
G Asnsd1 asparagine synthetase domain containing 1 involved_in IEA GO_REF:0000043
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 9:55,618,799...55,631,064
Ensembl chr 9:55,618,799...55,631,064 		JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:4193185) 		GO_Central
Ensembl
RGD		 PMID:4193185 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871 		JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:71,563,562...71,576,446
Ensembl chr16:71,563,534...71,570,468 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (PMID:4193185) RGD PMID:4193185 NCBI chr19:9,180,428...9,206,113
Ensembl chr19:9,180,431...9,206,111 		JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 involved_in ISO
IEA 		(PMID:10934207)
GO_REF:0000107 		RGD
Ensembl		 PMID:10934207 GO_REF:0000107 NCBI chr 8:101,964,318...102,047,022
Ensembl chr 8:101,964,318...102,047,022 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:16447251) 		Ensembl
RGD		 PMID:16447251 GO_REF:0000107 NCBI chr12:25,313,070...25,323,631
Ensembl chr12:25,313,072...25,323,631 		JBrowse link
L-asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050 		JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IBA
IEA 		(PMID:18230605)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:18230605 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:26,594,854...26,614,715 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in ISO
IEA
IBA 		(PMID:18230605)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:18230605 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:26,630,502...26,647,450
Ensembl chr 2:26,630,510...26,651,326 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:62,911,705...62,996,544
Ensembl chr17:62,911,771...62,996,541 		JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in ISO
IEA
ISS 		(PMID:15938715)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000104
GO_REF:0000041
GO_REF:0000024 		RGD
Ensembl
InterPro
UniProt		 PMID:15938715 GO_REF:0000002 GO_REF:0000024 GO_REF:0000041 GO_REF:0000104 GO_REF:0000107 NCBI chr 6:51,035,267...51,042,229
Ensembl chr 6:51,034,931...51,042,855 		JBrowse link
G Apip APAF1 interacting protein involved_in ISO
IEA
IBA 		(PMID:22837397), (PMID:23285211)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000104
GO_REF:0000041
GO_REF:0000033 		RGD
Ensembl
InterPro
UniProt
GO_Central		 PMID:22837397 PMID:23285211 GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 GO_REF:0000107 NCBI chr 3:109,886,919...109,913,295
Ensembl chr 3:109,886,953...109,915,862 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in ISO
IEA
IBA
ISS 		(PMID:15843022)
GO_REF:0000002
GO_REF:0000104
GO_REF:0000041
GO_REF:0000033
GO_REF:0000024 		RGD
InterPro
UniProt
GO_Central		 PMID:15843022 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 NCBI chr14:9,835,626...9,862,051
Ensembl chr14:9,835,627...9,873,668 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA
IBA 		GO_REF:0000041
GO_REF:0000104
GO_REF:0000033 		UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 NCBI chr19:40,812,114...40,819,846
Ensembl chr19:40,812,094...40,822,607 		JBrowse link
G Mtap methylthioadenosine phosphorylase involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000104
GO_REF:0000041 		GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 NCBI chr 5:108,990,270...109,036,494
Ensembl chr 5:108,988,830...109,055,214 		JBrowse link
lysine biosynthetic process via aminoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:9,731,592...9,748,934
Ensembl chr 8:9,738,172...9,748,953 		JBrowse link
G Aass aminoadipate-semialdehyde synthase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:52,572,146...52,628,811
Ensembl chr 4:52,572,147...52,657,600 		JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IEA GO_REF:0000043
GO_REF:0000117 		UniProt GO_REF:0000043 GO_REF:0000117 NCBI chr 6:51,035,267...51,042,229
Ensembl chr 6:51,034,931...51,042,855 		JBrowse link
G Apip APAF1 interacting protein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:109,886,919...109,913,295
Ensembl chr 3:109,886,953...109,915,862 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase involved_in
acts_upstream_of_or_within 		IDA
IEA
ISO 		GO_REF:0000002
GO_REF:0000117
(PMID:15217352) 		InterPro
UniProt
RGD		 PMID:15217352 PMID:15845641 GO_REF:0000002 GO_REF:0000117, RGD:1359026 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:26,594,854...26,614,715 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in IEA GO_REF:0000117
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000117 NCBI chr 2:26,630,502...26,647,450
Ensembl chr 2:26,630,510...26,651,326 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:9,835,626...9,862,051
Ensembl chr14:9,835,627...9,873,668 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr19:40,812,114...40,819,846
Ensembl chr19:40,812,094...40,822,607 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in
acts_upstream_of 		IEA
ISO 		GO_REF:0000043
(PMID:25633902) 		UniProt
RGD		 PMID:25633902 GO_REF:0000043 NCBI chr 6:100,713,510...100,781,013
Ensembl chr 6:100,713,681...100,781,957 		JBrowse link
G Mthfd1-ps1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1, pseudogene 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:136,648,931...136,652,187 JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:17,374,139...17,455,508
Ensembl chr14:17,374,144...17,454,322 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase acts_upstream_of_or_within
involved_in 		ISO
IBA 		MGI:2385823 (PMID:15217352)
GO_REF:0000033 		RGD
GO_Central		 PMID:15217352 GO_REF:0000033 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in
acts_upstream_of_or_within 		IDA
IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000002
GO_REF:0000043
GO_REF:0000033
PMID:20424322
MGI:2180496 (PMID:11158293)
(PMID:23825108) 		Ensembl
InterPro
UniProt
GO_Central
RGD		 PMID:11158293 PMID:23825108 PMID:15845641 PMID:20424322 PMID:11730351 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107, RGD:1359026, RGD:10054082, RGD:1601423 NCBI chr17:62,911,705...62,996,544
Ensembl chr17:62,911,771...62,996,541 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO
IEA
IBA 		(PMID:11466310)
GO_REF:0000117
GO_REF:0000033
GO_REF:0000043
(PMID:17369066) 		RGD
UniProt
GO_Central		 PMID:11466310 PMID:17369066 GO_REF:0000033 GO_REF:0000043 GO_REF:0000117 NCBI chr 1:36,695,376...36,727,341
Ensembl chr 1:36,695,460...36,727,807 		JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thnsl2 threonine synthase-like 2 NOT|acts_upstream_of_or_within ISO (PMID:17034760) RGD PMID:17034760 NCBI chr 4:104,671,305...104,691,084
Ensembl chr 4:104,670,925...104,691,959 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20667
    cellular process 19647
      metabolic process 12252
        primary metabolic process 10847
          amino acid metabolic process 312
            proteinogenic amino acid metabolic process 186
              proteinogenic amino acid biosynthetic process 62
                aspartate family amino acid biosynthetic process 23
                  L-isoleucine biosynthetic process 0
                  asparagine biosynthetic process + 2
                  aspartate biosynthetic process 3
                  hydroxylysine biosynthetic process 2
                  lysine biosynthetic process + 2
                  methionine biosynthetic process + 13
                  threonine biosynthetic process 1
Path 2
Term Annotations click to browse term
  biological_process 20667
    cellular process 19647
      metabolic process 12252
        small molecule metabolic process 1983
          organic acid metabolic process 1082
            oxoacid metabolic process 1068
              carboxylic acid metabolic process 1053
                alpha-amino acid metabolic process 229
                  L-amino acid metabolic process 196
                    L-amino acid biosynthetic process 56
                      aspartate family amino acid biosynthetic process 23
                        L-isoleucine biosynthetic process 0
                        asparagine biosynthetic process + 2
                        aspartate biosynthetic process 3
                        hydroxylysine biosynthetic process 2
                        lysine biosynthetic process + 2
                        methionine biosynthetic process + 13
                        threonine biosynthetic process 1
paths to the root