ONTOLOGY REPORT - ANNOTATIONS |
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Term: | aspartate family amino acid metabolic process |
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Accession: | GO:0009066
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browse the term
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Definition: | The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. |
Synonyms: | exact_synonym: | aspartate family amino acid metabolism |
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Aspg |
asparaginase |
involved_in |
IEA |
GO_REF:0000117 |
UniProt |
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GO_REF:0000117 |
NCBI chr 6:131,176,727...131,196,268
Ensembl chr 6:131,176,874...131,196,268
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Bhmt |
betaine-homocysteine S-methyltransferase |
involved_in |
ISO IEA |
(PMID:10529246) GO_REF:0000107 |
RGD Ensembl |
PMID:10529246 |
GO_REF:0000107 |
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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Asns |
asparagine synthetase (glutamine-hydrolyzing) |
involved_in acts_upstream_of_or_within |
IDA IBA ISO |
GO_REF:0000033 (PMID:2573597) |
GO_Central RGD |
PMID:2573597 PMID:2887559 |
GO_REF:0000033, RGD:2316002 |
NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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Asnsd1 |
asparagine synthetase domain containing 1 |
involved_in |
IEA |
GO_REF:0000043 |
UniProt |
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GO_REF:0000043 |
NCBI chr 9:48,126,808...48,139,073
Ensembl chr 9:48,126,808...48,139,073
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Asrgl1 |
asparaginase and isoaspartyl peptidase 1 |
involved_in acts_upstream_of_or_within |
ISO IBA IDA |
(PMID:19839645) GO_REF:0000033 PMID:12753071 |
RGD GO_Central |
PMID:19839645 PMID:12753071 PMID:12753071 |
GO_REF:0000033, RGD:1299508, RGD:1299508 |
NCBI chr 1:206,006,103...206,027,115
Ensembl chr 1:206,006,109...206,027,108
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Aspg |
asparaginase |
involved_in |
IDA |
PMID:9575212 |
UniProt |
PMID:9575212 |
RGD:1299414 |
NCBI chr 6:131,176,727...131,196,268
Ensembl chr 6:131,176,874...131,196,268
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Nit2 |
nitrilase family, member 2 |
involved_in |
ISO IBA IEA |
(PMID:22674578) GO_REF:0000033 GO_REF:0000107 |
RGD GO_Central Ensembl |
PMID:22674578 |
GO_REF:0000033 GO_REF:0000107 |
NCBI chr11:43,363,839...43,378,713
Ensembl chr11:43,363,985...43,375,024
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Got1 |
glutamic-oxaloacetic transaminase 1 |
involved_in acts_upstream_of_or_within |
IEA ISO IBA |
GO_REF:0000107 (PMID:4193185) GO_REF:0000033 |
Ensembl RGD GO_Central |
PMID:4193185 |
GO_REF:0000033 GO_REF:0000107 |
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
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Got1l1 |
glutamic-oxaloacetic transaminase 1-like 1 |
involved_in |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr16:64,860,308...64,873,656
Ensembl chr16:64,860,704...64,866,162
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Got2 |
glutamic-oxaloacetic transaminase 2 |
acts_upstream_of_or_within |
ISO |
(PMID:4193185) |
RGD |
PMID:4193185 |
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NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
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Ddo |
D-aspartate oxidase |
involved_in |
ISO IBA |
(PMID:9163533) GO_REF:0000033 |
RGD GO_Central |
PMID:9163533 |
GO_REF:0000033 |
NCBI chr20:44,090,823...44,109,962
Ensembl chr20:44,090,914...44,133,095
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Got1 |
glutamic-oxaloacetic transaminase 1 |
involved_in |
ISO IEA |
(PMID:2241899) GO_REF:0000107 |
RGD Ensembl |
PMID:2241899 |
GO_REF:0000107 |
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
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Got2 |
glutamic-oxaloacetic transaminase 2 |
involved_in |
ISO IBA |
(PMID:2567216) GO_REF:0000033 |
RGD GO_Central |
PMID:2567216 |
GO_REF:0000033 |
NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
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Adss1 |
adenylosuccinate synthase 1 |
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IDA |
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RGD |
PMID:3759987 |
RGD:5135303 |
NCBI chr 6:131,679,795...131,702,012
Ensembl chr 6:131,679,701...131,701,998
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Adss2 |
adenylosuccinate synthase 2 |
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IDA |
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RGD |
PMID:71897 |
RGD:5135533 |
NCBI chr13:89,769,240...89,799,577
Ensembl chr13:89,769,244...89,799,604
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Aspa |
aspartoacylase |
involved_in |
ISO |
MGI:2447776 (PMID:28077719) |
RGD |
PMID:28077719 |
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NCBI chr10:57,891,704...57,945,267
Ensembl chr10:57,892,104...57,945,272
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Ass1 |
argininosuccinate synthase 1 |
involved_in |
ISO |
(PMID:7977368) |
RGD |
PMID:7977368 |
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NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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Ddo |
D-aspartate oxidase |
acts_upstream_of_or_within |
ISO |
MGI:3625623 (PMID:16525061) |
RGD |
PMID:16525061 |
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NCBI chr20:44,090,823...44,109,962
Ensembl chr20:44,090,914...44,133,095
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Got1 |
glutamic-oxaloacetic transaminase 1 |
involved_in |
IDA ISS |
GO_REF:0000024 |
UniProt RGD |
PMID:2837211 |
GO_REF:0000024, RGD:2289377 |
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
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Got2 |
glutamic-oxaloacetic transaminase 2 |
involved_in |
IMP ISS |
GO_REF:0000024 |
UniProt RGD |
PMID:12686151 |
GO_REF:0000024, RGD:2289396 |
NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
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Nat8l |
N-acetyltransferase 8-like |
involved_in |
ISO |
MGI:87914 (PMID:28077719) |
RGD |
PMID:28077719 |
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NCBI chr14:76,756,077...76,762,712
Ensembl chr14:76,756,077...76,763,411
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Got1 |
glutamic-oxaloacetic transaminase 1 |
involved_in acts_upstream_of_or_within |
IEA ISO |
GO_REF:0000107 (PMID:4193185) |
Ensembl RGD |
PMID:4193185 |
GO_REF:0000107 |
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
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Got2 |
glutamic-oxaloacetic transaminase 2 |
acts_upstream_of_or_within |
ISO |
(PMID:4193185) |
RGD |
PMID:4193185 |
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NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
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Plod2 |
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 |
involved_in |
ISO IEA |
(PMID:10934207) GO_REF:0000107 |
RGD Ensembl |
PMID:10934207 |
GO_REF:0000107 |
NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
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Plod3 |
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 |
involved_in |
ISO IEA |
(MGI:6202004|PMID:16447251) (PMID:16447251) GO_REF:0000107 |
RGD Ensembl |
PMID:16447251 |
GO_REF:0000107 MGI:6202004 |
NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960
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Asns |
asparagine synthetase (glutamine-hydrolyzing) |
involved_in |
IEA |
GO_REF:0000041 |
UniProt |
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GO_REF:0000041 |
NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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Atf4 |
activating transcription factor 4 |
involved_in |
ISO |
(PMID:11960987) |
RGD |
PMID:11960987 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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Aass |
aminoadipate-semialdehyde synthase |
acts_upstream_of_or_within |
ISO |
(PMID:10567240) |
RGD |
PMID:10567240 |
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NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
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Pipox |
pipecolic acid and sarcosine oxidase |
involved_in |
ISO IBA |
(PMID:10642506) GO_REF:0000033 |
RGD GO_Central |
PMID:10642506 |
GO_REF:0000033 |
NCBI chr10:62,769,874...62,783,484
Ensembl chr10:62,769,900...62,782,370
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Aadat |
aminoadipate aminotransferase |
involved_in |
IEA |
GO_REF:0000041 |
UniProt |
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GO_REF:0000041 |
NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332
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Aass |
aminoadipate-semialdehyde synthase |
involved_in |
IEA |
GO_REF:0000041 |
UniProt |
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GO_REF:0000041 |
NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
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Dlst |
dihydrolipoamide S-succinyltransferase |
involved_in |
IEA |
GO_REF:0000041 |
UniProt |
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GO_REF:0000041 |
NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
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Bhmt |
betaine-homocysteine S-methyltransferase |
involved_in |
ISO IEA IBA |
(PMID:18230605) GO_REF:0000107 GO_REF:0000033 |
RGD Ensembl GO_Central |
PMID:18230605 |
GO_REF:0000033 GO_REF:0000107 |
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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Bhmt2 |
betaine-homocysteine S-methyltransferase 2 |
involved_in |
IEA ISO IBA |
GO_REF:0000107 (PMID:18230605) GO_REF:0000033 |
Ensembl RGD GO_Central |
PMID:18230605 |
GO_REF:0000033 GO_REF:0000107 |
NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475
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Adi1 |
acireductone dioxygenase 1 |
involved_in |
IEA ISS ISO |
GO_REF:0000041 GO_REF:0000024 (PMID:15938715) |
UniProt RGD |
PMID:15938715 |
GO_REF:0000024 GO_REF:0000041 |
NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842
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Apip |
APAF1 interacting protein |
involved_in |
IEA IBA ISO |
GO_REF:0000041 GO_REF:0000033 (PMID:22837397), (PMID:23285211) |
UniProt GO_Central RGD |
PMID:22837397 PMID:23285211 |
GO_REF:0000033 GO_REF:0000041 |
NCBI chr 3:89,431,964...89,458,000
Ensembl chr 3:89,432,037...89,458,340
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Enoph1 |
enolase-phosphatase 1 |
involved_in |
IEA IBA ISO ISS |
GO_REF:0000041 GO_REF:0000033 (PMID:15843022) GO_REF:0000024 |
UniProt GO_Central RGD |
PMID:15843022 |
GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 |
NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273
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Mri1 |
methylthioribose-1-phosphate isomerase 1 |
involved_in |
IEA IBA |
GO_REF:0000041 GO_REF:0000033 |
UniProt GO_Central |
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GO_REF:0000033 GO_REF:0000041 |
NCBI chr19:23,907,327...23,913,721
Ensembl chr19:23,907,335...23,913,320
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Mtap |
methylthioadenosine phosphorylase |
involved_in |
IEA IBA |
GO_REF:0000041 GO_REF:0000033 |
UniProt GO_Central |
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GO_REF:0000033 GO_REF:0000041 |
NCBI chr 5:103,874,460...103,920,684
Ensembl chr 5:103,873,020...103,939,406
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Apip |
APAF1 interacting protein |
involved_in |
IEA |
GO_REF:0000104 |
UniProt |
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GO_REF:0000104 |
NCBI chr 3:89,431,964...89,458,000
Ensembl chr 3:89,432,037...89,458,340
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Enoph1 |
enolase-phosphatase 1 |
involved_in |
IEA |
GO_REF:0000104 |
UniProt |
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GO_REF:0000104 |
NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273
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Mri1 |
methylthioribose-1-phosphate isomerase 1 |
involved_in |
IEA |
GO_REF:0000104 |
UniProt |
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GO_REF:0000104 |
NCBI chr19:23,907,327...23,913,721
Ensembl chr19:23,907,335...23,913,320
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Aasdhppt |
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
involved_in |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr 8:1,453,226...1,463,990
Ensembl chr 8:1,452,282...1,463,966
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Aass |
aminoadipate-semialdehyde synthase |
involved_in |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
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Bhmt |
betaine-homocysteine S-methyltransferase |
acts_upstream_of_or_within |
IDA ISO |
(PMID:15217352) |
RGD |
PMID:15217352 PMID:15845641 |
RGD:1359026 |
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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G |
Bhmt2 |
betaine-homocysteine S-methyltransferase 2 |
involved_in |
IEA |
GO_REF:0000117 |
UniProt |
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GO_REF:0000117 |
NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475
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Mthfd1 |
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 |
involved_in |
ISO IEA |
(PMID:25633902) GO_REF:0000107 |
RGD Ensembl |
PMID:25633902 |
GO_REF:0000107 |
NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
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G |
Mthfd2l |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
involved_in |
IEA |
GO_REF:0000043 |
UniProt |
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GO_REF:0000043 |
NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112
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Mthfr |
methylenetetrahydrofolate reductase |
involved_in acts_upstream_of_or_within |
IBA ISO |
GO_REF:0000033 MGI:2385823 (PMID:15217352) |
GO_Central RGD |
PMID:15217352 |
GO_REF:0000033 |
NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
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Mtr |
5-methyltetrahydrofolate-homocysteine methyltransferase |
acts_upstream_of_or_within involved_in |
IDA ISO IBA |
MGI:2180496 (PMID:11158293) PMID:20424322 GO_REF:0000033 (PMID:23825108) |
RGD GO_Central |
PMID:11158293 PMID:23825108 PMID:15845641 PMID:20424322 PMID:11730351 |
GO_REF:0000033, RGD:1359026, RGD:10054082, RGD:1601423 |
NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
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Mtrr |
5-methyltetrahydrofolate-homocysteine methyltransferase reductase |
involved_in |
ISO IBA IEA |
(PMID:11466310) (PMID:17369066) GO_REF:0000033 GO_REF:0000043 (MGI:3710265|PMID:17369066) |
RGD GO_Central UniProt |
PMID:11466310 PMID:17369066 |
GO_REF:0000033 GO_REF:0000043 MGI:3710265 |
NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425
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Mat1a |
methionine adenosyltransferase 1A |
involved_in |
ISO ISS |
(PMID:10677294) GO_REF:0000024 |
RGD UniProt |
PMID:10677294 |
GO_REF:0000024 |
NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274
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G |
Adi1 |
acireductone dioxygenase 1 |
involved_in |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842
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Gnmt |
glycine N-methyltransferase |
acts_upstream_of_or_within |
ISO |
MGI:3842652 (PMID:17937387) |
RGD |
PMID:17937387 |
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NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
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Mthfd1 |
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 |
involved_in |
ISO |
(MGI:5621260|PMID:23190757) |
RGD |
PMID:23190757 |
MGI:5621260 |
NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
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Mthfr |
methylenetetrahydrofolate reductase |
involved_in |
ISO |
UniProtKB:P53128 (PMID:10551815) |
RGD |
PMID:10551815 |
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NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
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Mtr |
5-methyltetrahydrofolate-homocysteine methyltransferase |
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IMP |
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RGD |
PMID:21121936 |
RGD:7207080 |
NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
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Thnsl2 |
threonine synthase-like 2 |
NOT|acts_upstream_of_or_within |
ISO |
(PMID:17034760) |
RGD |
PMID:17034760 |
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NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017
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Gcat |
glycine C-acetyltransferase |
involved_in |
IEA |
GO_REF:0000002 |
InterPro |
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GO_REF:0000002 |
NCBI chr 7:110,595,126...110,601,474
Ensembl chr 7:110,595,091...110,601,473
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Sds |
serine dehydratase |
involved_in |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
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Sdsl |
serine dehydratase-like |
involved_in |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr12:36,099,693...36,109,914
Ensembl chr12:36,099,693...36,109,906
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Tdh |
L-threonine dehydrogenase |
involved_in acts_upstream_of_or_within |
ISO IBA |
(MGI:5905531|PMID:26492815) (PMID:26492815) (PMID:21896756) GO_REF:0000033 |
RGD GO_Central |
PMID:21896756 PMID:26492815 |
GO_REF:0000033 MGI:5905531 |
NCBI chr15:37,739,823...37,753,365
Ensembl chr15:37,739,823...37,753,365
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Tha1 |
threonine aldolase 1 |
involved_in |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr10:103,094,681...103,100,169
Ensembl chr10:103,094,681...103,100,519
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Phgdh |
phosphoglycerate dehydrogenase |
acts_upstream_of_or_within |
ISO |
MGI:3769591 (PMID:19114063) |
RGD |
PMID:19114063 |
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NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
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Term paths to the root
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