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ONTOLOGY REPORT - ANNOTATIONS


Term:aspartate family amino acid metabolic process
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Accession:GO:0009066 term browser browse the term
Definition:The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
Synonyms:exact_synonym: aspartate family amino acid metabolism



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aspartate family amino acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASPG asparaginase involved_in IEA UniProt GO_REF:0000117
asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASNS asparagine synthetase (glutamine-hydrolyzing) involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(PMID:2573597)
GO_Central
MGI
RGD
PMID:2573597 PMID:2887559 PMID:21873635 RGD:2316002 NCBI chr 9:77,318,341...77,336,290
Ensembl chr 9:77,318,213...77,509,020
JBrowse link
G ASNSD1 asparagine synthetase domain containing 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr15:94,261,910...94,272,129
Ensembl chr15:94,261,905...94,272,129
JBrowse link
asparagine catabolic process via L-aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASRGL1 asparaginase and isoaspartyl peptidase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
(PMID:21873635)
PMID:12753071
GO_Central
MGI
Ensembl
PMID:12753071 PMID:21873635 GO_REF:0000107 RGD:1299508 NCBI chr 2:9,328,260...9,353,384
Ensembl chr 2:9,328,269...9,353,340
JBrowse link
asparagine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASPG asparaginase involved_in ISO PMID:9575212 UniProt PMID:9575212 RGD:1299414
G DEDD death effector domain containing involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:89,311,308...89,323,692
Ensembl chr 4:89,311,310...89,323,724
JBrowse link
G NIT2 nitrilase family member 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:158,630,997...158,653,164
Ensembl chr13:158,630,743...158,653,095
JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GOT1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:53641|PMID:4193185)
GO_Central
MGI
PMID:4193185 PMID:21873635 MGI:53641 NCBI chr14:110,608,422...110,635,825
Ensembl chr14:110,608,430...110,635,874
JBrowse link
G GOT1L1 glutamic-oxaloacetic transaminase 1 like 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:48,500,156...48,506,992
Ensembl chr15:48,500,068...48,507,021
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:53641|PMID:4193185) Ensembl
MGI
PMID:4193185 GO_REF:0000107 MGI:53641 NCBI chr 6:20,407,203...20,431,849
Ensembl chr 6:20,407,198...20,432,068
JBrowse link
aspartate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDO D-aspartate oxidase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:76,391,112...76,417,147
Ensembl chr 1:76,390,493...76,417,301
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:110,608,422...110,635,825
Ensembl chr14:110,608,430...110,635,874
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 involved_in IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 6:20,407,203...20,431,849
Ensembl chr 6:20,407,198...20,432,068
JBrowse link
aspartate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADSS1 adenylosuccinate synthase 1 ISO RGD PMID:3759987 RGD:5135303
G ADSS2 adenylosuccinate synthase 2 ISO RGD PMID:71897 RGD:5135533 NCBI chr10:17,220,081...17,259,141
Ensembl chr10:17,220,208...17,259,166
JBrowse link
G ASS1 argininosuccinate synthase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:270,531,434...270,586,364
Ensembl chr 1:270,531,589...270,586,361
JBrowse link
G BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:126,168,944...126,184,813
Ensembl chr 1:126,165,991...126,184,870
JBrowse link
G DDO D-aspartate oxidase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3617951|PMID:16525061) Ensembl
MGI
PMID:16525061 GO_REF:0000107 MGI:3617951 NCBI chr 1:76,391,112...76,417,147
Ensembl chr 1:76,390,493...76,417,301
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 involved_in ISS
ISO
UniProt
RGD
PMID:2837211 GO_REF:0000024 RGD:2289377 NCBI chr14:110,608,422...110,635,825
Ensembl chr14:110,608,430...110,635,874
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 involved_in ISS
ISO
UniProt
RGD
PMID:12686151 GO_REF:0000024 RGD:2289396 NCBI chr 6:20,407,203...20,431,849
Ensembl chr 6:20,407,198...20,432,068
JBrowse link
glutamate catabolic process to aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GOT1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:53641|PMID:4193185) Ensembl
MGI
PMID:4193185 GO_REF:0000107 MGI:53641 NCBI chr14:110,608,422...110,635,825
Ensembl chr14:110,608,430...110,635,874
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:53641|PMID:4193185) Ensembl
MGI
PMID:4193185 GO_REF:0000107 MGI:53641 NCBI chr 6:20,407,203...20,431,849
Ensembl chr 6:20,407,198...20,432,068
JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:86,402,673...86,513,167
Ensembl chr13:86,401,244...86,513,105
JBrowse link
G PLOD3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,911,787...8,919,525
Ensembl chr 3:8,911,787...8,919,516
JBrowse link
L-asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASNS asparagine synthetase (glutamine-hydrolyzing) involved_in IEA UniProt GO_REF:0000041 NCBI chr 9:77,318,341...77,336,290
Ensembl chr 9:77,318,213...77,509,020
JBrowse link
L-asparagine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,738,880...8,745,225
JBrowse link
L-lysine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AASS aminoadipate-semialdehyde synthase acts_upstream_of_or_within ISO (MGI:1350812|PMID:10567240) MGI PMID:10567240 MGI:1350812 NCBI chr18:24,938,366...25,039,197
Ensembl chr18:24,974,816...25,039,196
JBrowse link
L-lysine catabolic process to acetyl-CoA via L-pipecolate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100515508 peroxisomal sarcosine oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:45,306,327...45,319,938
Ensembl chr12:45,257,188...45,322,767
JBrowse link
G LOC110255229 peroxisomal sarcosine oxidase involved_in IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr12:45,256,806...45,270,755
Ensembl chr12:45,257,188...45,322,767
JBrowse link
L-lysine catabolic process to acetyl-CoA via saccharopine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AASS aminoadipate-semialdehyde synthase involved_in IEA UniProt GO_REF:0000041 NCBI chr18:24,938,366...25,039,197
Ensembl chr18:24,974,816...25,039,196
JBrowse link
G DLST dihydrolipoamide S-succinyltransferase involved_in IEA UniProt GO_REF:0000041 NCBI chr 7:98,091,161...98,111,267
Ensembl chr 7:98,091,123...98,111,572
JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHMT betaine--homocysteine S-methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:87,911,093...87,935,252
Ensembl chr 2:87,866,607...87,935,253
JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 involved_in ISO (PMID:18230605) BHF-UCL PMID:18230605 NCBI chr 2:87,866,631...87,882,623
Ensembl chr 2:87,866,607...87,935,253
JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADI1 acireductone dioxygenase 1 involved_in IEA UniProt GO_REF:0000041 NCBI chr 3:131,295,257...131,303,663
Ensembl chr 3:131,295,257...131,304,337
JBrowse link
G APIP APAF1 interacting protein involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr 2:26,095,020...26,115,462
Ensembl chr 2:26,095,038...26,115,464
JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
UniProt
PMID:21873635 GO_REF:0000002 GO_REF:0000041 NCBI chr 8:135,775,743...135,802,404
Ensembl chr 8:135,775,745...135,802,388
JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr 2:65,348,609...65,354,892
Ensembl chr 2:65,348,004...65,354,919
JBrowse link
G MTAP methylthioadenosine phosphorylase involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr 1:200,882,954...200,934,389
Ensembl chr 1:200,882,955...200,934,639
JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APIP APAF1 interacting protein involved_in IEA UniProt GO_REF:0000104 NCBI chr 2:26,095,020...26,115,462
Ensembl chr 2:26,095,038...26,115,464
JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr 8:135,775,743...135,802,404
Ensembl chr 8:135,775,745...135,802,388
JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr 2:65,348,609...65,354,892
Ensembl chr 2:65,348,004...65,354,919
JBrowse link
L-threonine catabolic process to glycine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TDH L-threonine 3-dehydrogenase involved_in IEA UniProt GO_REF:0000041 NCBI chr14:14,577,009...14,597,695 JBrowse link
lysine biosynthetic process via aminoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:35,903,902...35,948,573
Ensembl chr 9:35,904,029...35,948,575
JBrowse link
G AASS aminoadipate-semialdehyde synthase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:24,938,366...25,039,197
Ensembl chr18:24,974,816...25,039,196
JBrowse link
lysine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:126,168,944...126,184,813
Ensembl chr 1:126,165,991...126,184,870
JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHMT betaine--homocysteine S-methyltransferase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3510291|PMID:15217352) InterPro
UniProt
MGI
RGD
PMID:15217352 PMID:15845641 GO_REF:0000002 GO_REF:0000117 MGI:3510291 RGD:1359026 NCBI chr 2:87,911,093...87,935,252
Ensembl chr 2:87,866,607...87,935,253
JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr 2:87,866,631...87,882,623
Ensembl chr 2:87,866,607...87,935,253
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) BHF-UCL PMID:25633902 NCBI chr 7:88,471,317...88,533,690
Ensembl chr 7:88,471,414...88,537,600
JBrowse link
G MTHFR methylenetetrahydrofolate reductase involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3510291|PMID:15217352)
GO_Central
MGI
PMID:15217352 PMID:21873635 MGI:3510291 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,636...71,881,820
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:1930456|PMID:11158293) RGD
UniProt
MGI
PMID:11158293 PMID:11730351 PMID:15845641 GO_REF:0000117 MGI:1930456 RGD:1359026 RGD:1601423 NCBI chr14:54,546,978...54,652,780
Ensembl chr14:54,546,981...54,652,759
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr16:74,245,214...74,270,828
Ensembl chr16:74,245,224...74,270,802
JBrowse link
methionine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAT1A methionine adenosyltransferase 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:82,109,405...82,126,487
Ensembl chr14:82,109,404...82,127,049
JBrowse link
methionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADI1 acireductone dioxygenase 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:131,295,257...131,303,663
Ensembl chr 3:131,295,257...131,304,337
JBrowse link
G GNMT glycine N-methyltransferase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3842675|PMID:17937387) Ensembl
MGI
PMID:17937387 GO_REF:0000107 MGI:3842675 NCBI chr 7:38,038,359...38,041,218
Ensembl chr 7:38,038,358...38,041,218
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (MGI:5621260|PMID:23190757) BHF-UCL PMID:23190757 MGI:5621260 NCBI chr 7:88,471,317...88,533,690
Ensembl chr 7:88,471,414...88,537,600
JBrowse link
G MTHFR methylenetetrahydrofolate reductase involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,636...71,881,820
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:21121936 RGD:7207080 NCBI chr14:54,546,978...54,652,780
Ensembl chr14:54,546,981...54,652,759
JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G THNSL2 threonine synthase like 2 NOT|acts_upstream_of_or_within ISO (MGI:3690523|PMID:17034760) MGI PMID:17034760 MGI:3690523 NCBI chr 3:57,800,976...57,821,296
Ensembl chr 3:57,799,026...57,823,440
JBrowse link
threonine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCAT glycine C-acetyltransferase involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:10,027,133...10,038,494
Ensembl chr 5:10,011,009...10,038,433
JBrowse link
G LOC110255953 probable low-specificity L-threonine aldolase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:3,728,742...3,734,209 JBrowse link
G SDS serine dehydratase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:38,503,922...38,513,908
Ensembl chr14:38,503,930...38,513,880
JBrowse link
G SDSL serine dehydratase like involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:38,471,162...38,484,459
Ensembl chr14:38,471,165...38,484,155
JBrowse link
G TDH L-threonine 3-dehydrogenase involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
(MGI:5292271|PMID:21896756)
(PMID:21873635)
UniProt
MGI
GO_Central
PMID:21873635 PMID:21896756 GO_REF:0000024 MGI:5292271 NCBI chr14:14,577,009...14,597,695 JBrowse link
threonine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PHGDH phosphoglycerate dehydrogenase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3835979|PMID:19114063) Ensembl
MGI
PMID:19114063 GO_REF:0000107 MGI:3835979 NCBI chr 4:101,445,977...101,478,144
Ensembl chr 4:101,408,308...101,478,144
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16673
    metabolic process 10521
      primary metabolic process 9354
        cellular amino acid metabolic process 271
          alpha-amino acid metabolic process 192
            aspartate family amino acid metabolic process 42
              asparagine metabolic process + 7
              aspartate family amino acid biosynthetic process + 21
              aspartate family amino acid catabolic process + 14
              aspartate metabolic process + 8
              hydroxylysine metabolic process + 2
              lysine metabolic process + 6
              methionine metabolic process + 13
              threonine metabolic process + 7
Path 2
Term Annotations click to browse term
  biological_process 16673
    metabolic process 10521
      cellular metabolic process 9547
        organic acid metabolic process 888
          oxoacid metabolic process 861
            carboxylic acid metabolic process 844
              cellular amino acid metabolic process 271
                alpha-amino acid metabolic process 192
                  aspartate family amino acid metabolic process 42
                    asparagine metabolic process + 7
                    aspartate family amino acid biosynthetic process + 21
                    aspartate family amino acid catabolic process + 14
                    aspartate metabolic process + 8
                    hydroxylysine metabolic process + 2
                    lysine metabolic process + 6
                    methionine metabolic process + 13
                    threonine metabolic process + 7
paths to the root