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ONTOLOGY REPORT - ANNOTATIONS


Term:aspartate family amino acid metabolic process
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Accession:GO:0009066 term browser browse the term
Definition:The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
Synonyms:exact_synonym: aspartate family amino acid metabolism



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asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase involved_in
acts_upstream_of_or_within
IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
RGD
PMID:2887559 PMID:21873635 GO_REF:0000008 GO_REF:0000096 MGI:2154458 MGI:4417868 MGI:6201960 RGD:2316002 NCBI chr 6:7,675,165...7,693,209
Ensembl chr 6:7,675,169...7,693,254
JBrowse link
asparagine catabolic process via L-aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asrgl1 asparaginase like 1 involved_in
acts_upstream_of_or_within
ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000008 GO_REF:0000096 MGI:2154458 MGI:4417868 MGI:4834177 MGI:6201960 NCBI chr19:9,111,719...9,135,566
Ensembl chr19:9,109,868...9,135,636
JBrowse link
asparagine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspg asparaginase involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr12:112,106,683...112,127,573
Ensembl chr12:112,106,679...112,127,559
JBrowse link
G Nit2 nitrilase family, member 2 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr16:57,156,665...57,167,332
Ensembl chr16:57,156,665...57,167,341
JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1, soluble acts_upstream_of_or_within
involved_in
IDA
IBA
(MGI:53641|PMID:4193185)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:4193185 PMID:21873635 MGI:53641 MGI:6201960 NCBI chr19:43,499,752...43,524,605
Ensembl chr19:43,499,752...43,524,605
JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 8:27,197,459...27,223,845
Ensembl chr 8:27,197,459...27,223,828
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial acts_upstream_of_or_within IDA (MGI:53641|PMID:4193185) MGI PMID:4193185 MGI:53641 NCBI chr 8:95,864,133...95,888,401
Ensembl chr 8:95,864,134...95,888,547
JBrowse link
aspartate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddo D-aspartate oxidase involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr10:40,630,011...40,681,847
Ensembl chr10:40,630,011...40,681,847
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:43,499,752...43,524,605
Ensembl chr19:43,499,752...43,524,605
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 8:95,864,133...95,888,401
Ensembl chr 8:95,864,134...95,888,547
JBrowse link
aspartate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adss adenylosuccinate synthetase, non muscle involved_in ISO RGD
MGI
PMID:71897 GO_REF:0000096 MGI:4417868 RGD:5135533 NCBI chr 1:177,763,176...177,796,695
Ensembl chr 1:177,762,962...177,796,511
JBrowse link
G Adssl1 adenylosuccinate synthetase like 1 involved_in ISO RGD
MGI
PMID:3759987 GO_REF:0000096 MGI:4417868 RGD:5135303 NCBI chr12:112,620,047...112,641,355
Ensembl chr12:112,620,045...112,641,360
JBrowse link
G Ass1 argininosuccinate synthetase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:31,470,270...31,520,670
Ensembl chr 2:31,470,207...31,520,672
JBrowse link
G Ddo D-aspartate oxidase acts_upstream_of_or_within IMP (MGI:3617951|PMID:16525061) MGI PMID:16525061 MGI:3617951 NCBI chr10:40,630,011...40,681,847
Ensembl chr10:40,630,011...40,681,847
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble involved_in ISO RGD
MGI
PMID:2837211 GO_REF:0000096 MGI:4417868 RGD:2289377 NCBI chr19:43,499,752...43,524,605
Ensembl chr19:43,499,752...43,524,605
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial involved_in ISO RGD
MGI
PMID:12686151 GO_REF:0000096 MGI:4417868 RGD:2289396 NCBI chr 8:95,864,133...95,888,401
Ensembl chr 8:95,864,134...95,888,547
JBrowse link
glutamate catabolic process to aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1, soluble acts_upstream_of_or_within IDA (MGI:53641|PMID:4193185) MGI PMID:4193185 MGI:53641 NCBI chr19:43,499,752...43,524,605
Ensembl chr19:43,499,752...43,524,605
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial acts_upstream_of_or_within IDA (MGI:53641|PMID:4193185) MGI PMID:4193185 MGI:53641 NCBI chr 8:95,864,133...95,888,401
Ensembl chr 8:95,864,134...95,888,547
JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:92,539,636...92,608,428
Ensembl chr 9:92,542,223...92,608,428
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 involved_in IDA (MGI:6202004|PMID:16447251) UniProt PMID:16447251 MGI:6202004 NCBI chr 5:136,987,019...136,996,646
Ensembl chr 5:136,987,019...136,996,648
JBrowse link
L-asparagine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:80,255,184...80,257,545
Ensembl chr15:80,255,184...80,257,541
JBrowse link
L-lysine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase acts_upstream_of_or_within IDA (MGI:1350812|PMID:10567240) MGI PMID:10567240 MGI:1350812 NCBI chr 6:23,072,173...23,132,986
Ensembl chr 6:23,072,173...23,132,986
JBrowse link
L-lysine catabolic process to acetyl-CoA via L-pipecolate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pipox pipecolic acid oxidase involved_in ISO
ISS
IBA
(MGI:1353685|PMID:10642506)
(MGI:6201960|PMID:21873635)
MGI
UniProt
GO_Central
PMID:10642506 PMID:21873635 GO_REF:0000096 MGI:1353685 MGI:4834177 MGI:6201960 NCBI chr11:77,880,614...77,893,872
Ensembl chr11:77,880,615...77,894,096
JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine methyltransferase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:93,616,891...93,637,758
Ensembl chr13:93,616,675...93,637,961
JBrowse link
G Bhmt2 betaine-homocysteine methyltransferase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:93,656,097...93,674,302
Ensembl chr13:93,655,720...93,674,302
JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:28,675,207...28,682,175
Ensembl chr12:28,675,231...28,682,175
JBrowse link
G Apip APAF1 interacting protein involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 2:103,073,675...103,092,649
Ensembl chr 2:103,073,675...103,092,644
JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 5:100,039,028...100,068,925
Ensembl chr 5:100,039,985...100,068,760
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 8:84,250,576...84,257,324
Ensembl chr 8:84,249,906...84,257,326
JBrowse link
G Mtap methylthioadenosine phosphorylase involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 4:89,137,370...89,181,090
Ensembl chr 4:89,137,122...89,181,081
JBrowse link
lysine biosynthetic process via aminoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:4,294,793...4,309,617
Ensembl chr 9:4,294,793...4,309,471
JBrowse link
G Aass aminoadipate-semialdehyde synthase involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 6:23,072,173...23,132,986
Ensembl chr 6:23,072,173...23,132,986
JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr12:28,675,207...28,682,175
Ensembl chr12:28,675,231...28,682,175
JBrowse link
G Apip APAF1 interacting protein acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr 2:103,073,675...103,092,649
Ensembl chr 2:103,073,675...103,092,644
JBrowse link
G Bhmt betaine-homocysteine methyltransferase acts_upstream_of_or_within
involved_in
IDA
ISO
(MGI:3510291|PMID:15217352) MGI
RGD
PMID:15217352 PMID:15845641 GO_REF:0000096 MGI:3510291 MGI:4417868 RGD:1359026 NCBI chr13:93,616,891...93,637,758
Ensembl chr13:93,616,675...93,637,961
JBrowse link
G Bhmt2 betaine-homocysteine methyltransferase 2 acts_upstream_of_or_within ISO (MGI:1927917|PMID:11087663) MGI PMID:11087663 MGI:1927917 NCBI chr13:93,656,097...93,674,302
Ensembl chr13:93,655,720...93,674,302
JBrowse link
G Enoph1 enolase-phosphatase 1 acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr 5:100,039,028...100,068,925
Ensembl chr 5:100,039,985...100,068,760
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr 8:84,250,576...84,257,324
Ensembl chr 8:84,249,906...84,257,326
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:76,254,406...76,319,820
Ensembl chr12:76,255,298...76,319,803
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr 5:90,930,873...91,021,368
Ensembl chr 5:90,931,117...91,021,368
JBrowse link
G Mthfr methylenetetrahydrofolate reductase acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:3510291|PMID:15217352)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:15217352 PMID:21873635 MGI:3510291 MGI:6201960 NCBI chr 4:148,039,077...148,059,562
Ensembl chr 4:148,039,077...148,059,551
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in
acts_upstream_of_or_within
ISO
IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:1930456|PMID:11158293)
MGI
GOC
RGD
PMID:11158293 PMID:11730351 PMID:15845641 PMID:21873635 GO_REF:0000096 MGI:1930456 MGI:4417868 MGI:4834177 MGI:6201960 RGD:1359026 RGD:1601423 NCBI chr13:12,181,331...12,258,199
Ensembl chr13:12,182,712...12,258,113
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO
IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:3710265|PMID:17369066)
MGI
GO_Central
BHF-UCL
PMID:17369066 PMID:21873635 GO_REF:0000096 MGI:3710265 MGI:4834177 MGI:6201960 NCBI chr13:68,560,780...68,582,169
Ensembl chr13:68,560,780...68,582,149
JBrowse link
methionine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mat1a methionine adenosyltransferase I, alpha involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr14:41,105,012...41,124,428
Ensembl chr14:41,105,035...41,124,412
JBrowse link
methionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr12:28,675,207...28,682,175
Ensembl chr12:28,675,231...28,682,175
JBrowse link
G Gnmt glycine N-methyltransferase acts_upstream_of_or_within IMP (MGI:3842675|PMID:17937387) MGI PMID:17937387 MGI:3842675 NCBI chr17:46,725,664...46,729,211
Ensembl chr17:46,725,664...46,729,168
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase involved_in IMP (MGI:5621260|PMID:23190757) BHF-UCL PMID:23190757 MGI:5621260 NCBI chr12:76,254,406...76,319,820
Ensembl chr12:76,255,298...76,319,803
JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:148,039,077...148,059,562
Ensembl chr 4:148,039,077...148,059,551
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in ISO RGD
MGI
PMID:21121936 GO_REF:0000096 MGI:4417868 RGD:7207080 NCBI chr13:12,181,331...12,258,199
Ensembl chr13:12,182,712...12,258,113
JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thnsl2 threonine synthase-like 2 (bacterial) NOT|acts_upstream_of_or_within IDA (MGI:3690523|PMID:17034760) MGI PMID:17034760 MGI:3690523 NCBI chr 6:71,128,166...71,144,380
Ensembl chr 6:71,128,166...71,144,439
JBrowse link
threonine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gcat glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase) involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr15:79,030,874...79,042,531
Ensembl chr15:79,030,874...79,038,353
Ensembl chr15:79,030,874...79,038,353
JBrowse link
G Sds serine dehydratase involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 5:120,476,547...120,483,932
Ensembl chr 5:120,476,526...120,483,932
JBrowse link
G Sdsl serine dehydratase-like involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 5:120,458,193...120,472,825
Ensembl chr 5:120,458,186...120,472,810
JBrowse link
G Tdh L-threonine dehydrogenase involved_in
acts_upstream_of_or_within
IDA
IBA
(MGI:5905531|PMID:26492815)
(MGI:6201960|PMID:21873635)
(MGI:5292271|PMID:21896756)
UniProt
GO_Central
MGI
PMID:21873635 PMID:21896756 PMID:26492815 MGI:5292271 MGI:5905531 MGI:6201960 NCBI chr14:63,492,347...63,509,092
Ensembl chr14:63,492,347...63,509,092
JBrowse link
G Tha1 threonine aldolase 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr11:117,867,949...117,873,526
Ensembl chr11:117,867,952...117,873,481
JBrowse link
threonine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phgdh 3-phosphoglycerate dehydrogenase acts_upstream_of_or_within IMP (MGI:3835979|PMID:19114063) MGI PMID:19114063 MGI:3835979 NCBI chr 3:98,313,171...98,339,969
Ensembl chr 3:98,313,170...98,339,990
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28627
    metabolic process 11326
      primary metabolic process 9959
        cellular amino acid metabolic process 263
          alpha-amino acid metabolic process 187
            aspartate family amino acid metabolic process 38
              asparagine metabolic process + 5
              aspartate family amino acid biosynthetic process + 21
              aspartate family amino acid catabolic process + 12
              aspartate metabolic process + 7
              hydroxylysine metabolic process + 2
              lysine metabolic process + 3
              methionine metabolic process + 14
              threonine metabolic process + 7
Path 2
Term Annotations click to browse term
  biological_process 28627
    metabolic process 11326
      cellular metabolic process 10136
        organic acid metabolic process 1002
          oxoacid metabolic process 970
            carboxylic acid metabolic process 950
              cellular amino acid metabolic process 263
                alpha-amino acid metabolic process 187
                  aspartate family amino acid metabolic process 38
                    asparagine metabolic process + 5
                    aspartate family amino acid biosynthetic process + 21
                    aspartate family amino acid catabolic process + 12
                    aspartate metabolic process + 7
                    hydroxylysine metabolic process + 2
                    lysine metabolic process + 3
                    methionine metabolic process + 14
                    threonine metabolic process + 7
paths to the root