ONTOLOGY REPORT - ANNOTATIONS |
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Term: | aspartate family amino acid metabolic process |
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Accession: | GO:0009066
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browse the term
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Definition: | The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. |
Synonyms: | exact_synonym: | aspartate family amino acid metabolism |
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ASPG |
asparaginase |
involved_in |
TAS IEA |
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Reactome UniProt |
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GO_REF:0000117 Reactome:R-HSA-8963693 |
NCBI chr14:104,085,700...104,115,582
Ensembl chr14:104,085,686...104,115,582
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NAT8L |
N-acetyltransferase 8 like |
involved_in |
TAS |
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Reactome |
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Reactome:R-HSA-8963693 |
NCBI chr 4:2,059,327...2,069,089
Ensembl chr 4:2,059,327...2,069,089
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BHMT |
betaine--homocysteine S-methyltransferase |
involved_in |
IMP |
(PMID:10529246) |
UniProt |
PMID:10529246 |
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NCBI chr 5:79,111,809...79,132,288
Ensembl chr 5:79,111,809...79,132,288
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ASNS |
asparagine synthetase (glutamine-hydrolyzing) |
involved_in acts_upstream_of_or_within |
ISO IBA IEA IDA IC |
(PMID:2573597) (PMID:2564390) |
RGD GO_Central UniProt MGI InterPro |
PMID:2564390 PMID:2573597 PMID:2887559 |
GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 RGD:2316002 |
NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542
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ASNSD1 |
asparagine synthetase domain containing 1 |
involved_in |
IEA |
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UniProt InterPro |
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GO_REF:0000002 GO_REF:0000043 |
NCBI chr 2:189,661,459...189,670,831
Ensembl chr 2:189,661,385...189,670,831
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ASRGL1 |
asparaginase and isoaspartyl peptidase 1 |
acts_upstream_of_or_within involved_in |
ISO IBA IDA ISS |
PMID:12753071 (PMID:19839645) |
MGI GO_Central UniProt |
PMID:12753071 PMID:19839645 |
GO_REF:0000024 GO_REF:0000033 RGD:1299508 |
NCBI chr11:62,337,448...62,401,431
Ensembl chr11:62,337,448...62,393,412
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ASPG |
asparaginase |
involved_in |
ISO |
PMID:9575212 |
UniProt |
PMID:9575212 |
RGD:1299414 |
NCBI chr14:104,085,700...104,115,582
Ensembl chr14:104,085,686...104,115,582
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NIT2 |
nitrilase family member 2 |
involved_in |
IDA IBA |
(PMID:22674578) |
BHF-UCL GO_Central |
PMID:22674578 |
GO_REF:0000033 |
NCBI chr 3:100,334,757...100,361,635
Ensembl chr 3:100,334,739...100,361,635
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GOT1 |
glutamic-oxaloacetic transaminase 1 |
involved_in acts_upstream_of_or_within |
IEA ISO IBA |
(PMID:4193185) |
Ensembl MGI GO_Central |
PMID:4193185 |
GO_REF:0000033 GO_REF:0000107 |
NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
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GOT1L1 |
glutamic-oxaloacetic transaminase 1 like 1 |
involved_in |
IBA |
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GO_Central |
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GO_REF:0000033 |
NCBI chr 8:37,934,281...37,940,124
Ensembl chr 8:37,934,281...37,940,124
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GOT2 |
glutamic-oxaloacetic transaminase 2 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:4193185) |
Ensembl MGI |
PMID:4193185 |
GO_REF:0000107 |
NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
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DDO |
D-aspartate oxidase |
involved_in |
IDA IBA |
(PMID:9163533) |
UniProt GO_Central |
PMID:9163533 |
GO_REF:0000033 |
NCBI chr 6:110,388,321...110,415,575
Ensembl chr 6:110,391,771...110,415,575
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GOT1 |
glutamic-oxaloacetic transaminase 1 |
involved_in |
IDA |
(PMID:2241899) |
UniProt |
PMID:2241899 |
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NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
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GOT2 |
glutamic-oxaloacetic transaminase 2 |
involved_in |
IDA IBA |
(PMID:2567216) |
UniProt GO_Central |
PMID:2567216 |
GO_REF:0000033 |
NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
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ADSS1 |
adenylosuccinate synthase 1 |
involved_in |
ISO IEA |
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RGD Ensembl |
PMID:3759987 |
GO_REF:0000107 RGD:5135303 |
NCBI chr14:104,724,229...104,747,325
Ensembl chr14:104,724,174...104,747,325
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ADSS2 |
adenylosuccinate synthase 2 |
involved_in |
ISO IEA |
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RGD Ensembl |
PMID:71897 |
GO_REF:0000107 RGD:5135533 |
NCBI chr 1:244,408,494...244,452,060
Ensembl chr 1:244,408,494...244,451,909
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ASPA |
aspartoacylase |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr17:3,474,110...3,503,405
Ensembl chr17:3,472,374...3,503,405
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ASS1 |
argininosuccinate synthase 1 |
involved_in |
IMP |
(PMID:7977368) |
BHF-UCL |
PMID:7977368 |
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NCBI chr 9:130,444,707...130,501,274
Ensembl chr 9:130,444,961...130,501,274
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DDO |
D-aspartate oxidase |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:16525061) |
Ensembl MGI |
PMID:16525061 |
GO_REF:0000107 |
NCBI chr 6:110,388,321...110,415,575
Ensembl chr 6:110,391,771...110,415,575
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GOT1 |
glutamic-oxaloacetic transaminase 1 |
involved_in |
ISO ISS |
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RGD UniProt |
PMID:2837211 |
GO_REF:0000024 RGD:2289377 |
NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
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GOT2 |
glutamic-oxaloacetic transaminase 2 |
involved_in |
ISO ISS |
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RGD UniProt |
PMID:12686151 |
GO_REF:0000024 RGD:2289396 |
NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
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NAT8L |
N-acetyltransferase 8 like |
involved_in |
ISO |
(PMID:28077719) |
MGI |
PMID:28077719 |
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NCBI chr 4:2,059,327...2,069,089
Ensembl chr 4:2,059,327...2,069,089
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GOT1 |
glutamic-oxaloacetic transaminase 1 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:4193185) |
Ensembl MGI |
PMID:4193185 |
GO_REF:0000107 |
NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
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GOT2 |
glutamic-oxaloacetic transaminase 2 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:4193185) |
Ensembl MGI |
PMID:4193185 |
GO_REF:0000107 |
NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
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PLOD2 |
procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 |
involved_in |
IDA |
(PMID:10934207) |
CAFA |
PMID:10934207 |
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NCBI chr 3:146,069,440...146,161,184
Ensembl chr 3:146,035,139...146,163,725
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PLOD3 |
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 7:101,205,984...101,217,581
Ensembl chr 7:101,205,977...101,218,420
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ASNS |
asparagine synthetase (glutamine-hydrolyzing) |
involved_in |
IEA |
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UniProt |
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GO_REF:0000041 |
NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542
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ATF4 |
activating transcription factor 4 |
involved_in |
IDA |
(PMID:11960987) |
UniProt |
PMID:11960987 |
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NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683
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AASS |
aminoadipate-semialdehyde synthase |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:10567240) |
Ensembl MGI |
PMID:10567240 |
GO_REF:0000107 |
NCBI chr 7:122,073,549...122,144,249
Ensembl chr 7:122,064,583...122,144,308
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PIPOX |
pipecolic acid and sarcosine oxidase |
involved_in |
IDA IBA |
(PMID:10642506) |
UniProt GO_Central |
PMID:10642506 |
GO_REF:0000033 |
NCBI chr17:29,043,141...29,057,216
Ensembl chr17:28,950,513...29,057,216
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AADAT |
aminoadipate aminotransferase |
involved_in |
IEA |
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UniProt |
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GO_REF:0000041 |
NCBI chr 4:170,060,222...170,094,292
Ensembl chr 4:170,060,222...170,091,699
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G |
AASS |
aminoadipate-semialdehyde synthase |
involved_in |
IEA |
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UniProt |
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GO_REF:0000041 |
NCBI chr 7:122,073,549...122,144,249
Ensembl chr 7:122,064,583...122,144,308
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DLST |
dihydrolipoamide S-succinyltransferase |
involved_in |
IEA |
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UniProt |
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GO_REF:0000041 |
NCBI chr14:74,881,916...74,903,743
Ensembl chr14:74,881,891...74,903,743
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BHMT |
betaine--homocysteine S-methyltransferase |
involved_in |
IDA IBA |
(PMID:18230605) |
BHF-UCL GO_Central |
PMID:18230605 |
GO_REF:0000033 |
NCBI chr 5:79,111,809...79,132,288
Ensembl chr 5:79,111,809...79,132,288
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BHMT2 |
betaine--homocysteine S-methyltransferase 2 |
involved_in |
IDA IBA |
(PMID:18230605) |
BHF-UCL GO_Central |
PMID:18230605 |
GO_REF:0000033 |
NCBI chr 5:79,069,767...79,090,069
Ensembl chr 5:79,069,767...79,090,069
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ADI1 |
acireductone dioxygenase 1 |
involved_in |
IDA IEA |
(PMID:15938715) |
UniProt InterPro |
PMID:15938715 |
GO_REF:0000002 GO_REF:0000041 GO_REF:0000104 |
NCBI chr 2:3,497,366...3,519,531
Ensembl chr 2:3,497,366...3,519,531
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APIP |
APAF1 interacting protein |
involved_in |
IEA IBA IMP |
(PMID:22837397), (PMID:23285211) |
UniProt GO_Central InterPro |
PMID:22837397 PMID:23285211 |
GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 |
NCBI chr11:34,882,295...34,916,379
Ensembl chr11:34,853,094...34,916,379
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ENOPH1 |
enolase-phosphatase 1 |
involved_in |
IEA IBA IDA |
(PMID:15843022) |
UniProt GO_Central InterPro |
PMID:15843022 |
GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 |
NCBI chr 4:82,430,590...82,461,177
Ensembl chr 4:82,430,590...82,461,177
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MRI1 |
methylthioribose-1-phosphate isomerase 1 |
involved_in |
TAS IBA IEA |
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Reactome GO_Central UniProt |
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GO_REF:0000033 GO_REF:0000041 Reactome:R-HSA-1237112 |
NCBI chr19:13,764,522...13,774,282
Ensembl chr19:13,764,522...13,774,282
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MTAP |
methylthioadenosine phosphorylase |
involved_in |
IEA IBA |
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UniProt GO_Central |
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GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 |
NCBI chr 9:21,802,636...21,941,115
Ensembl chr 9:21,802,636...21,937,651
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G |
APIP |
APAF1 interacting protein |
involved_in |
IEA |
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UniProt |
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GO_REF:0000104 |
NCBI chr11:34,882,295...34,916,379
Ensembl chr11:34,853,094...34,916,379
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ENOPH1 |
enolase-phosphatase 1 |
involved_in |
IEA |
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UniProt |
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GO_REF:0000104 |
NCBI chr 4:82,430,590...82,461,177
Ensembl chr 4:82,430,590...82,461,177
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G |
MRI1 |
methylthioribose-1-phosphate isomerase 1 |
involved_in |
IEA |
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UniProt |
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GO_REF:0000104 |
NCBI chr19:13,764,522...13,774,282
Ensembl chr19:13,764,522...13,774,282
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G |
RIDA |
reactive intermediate imine deaminase A homolog |
involved_in |
TAS |
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Reactome |
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Reactome:R-HSA-8849175 |
NCBI chr 8:98,102,344...98,117,171
Ensembl chr 8:98,102,344...98,117,171
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G |
AASDHPPT |
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
involved_in |
IBA |
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GO_Central |
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GO_REF:0000033 |
NCBI chr11:106,077,662...106,098,695
Ensembl chr11:106,075,501...106,098,699
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AASS |
aminoadipate-semialdehyde synthase |
involved_in |
IBA |
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GO_Central |
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GO_REF:0000033 |
NCBI chr 7:122,073,549...122,144,249
Ensembl chr 7:122,064,583...122,144,308
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G |
ADI1 |
acireductone dioxygenase 1 |
involved_in |
IEA |
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UniProt |
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GO_REF:0000043 |
NCBI chr 2:3,497,366...3,519,531
Ensembl chr 2:3,497,366...3,519,531
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G |
APIP |
APAF1 interacting protein |
involved_in |
IEA |
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UniProt |
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GO_REF:0000043 |
NCBI chr11:34,882,295...34,916,379
Ensembl chr11:34,853,094...34,916,379
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G |
BHMT |
betaine--homocysteine S-methyltransferase |
acts_upstream_of_or_within involved_in |
ISO IEA |
(PMID:15217352) |
RGD MGI UniProt InterPro |
PMID:15217352 PMID:15845641 |
GO_REF:0000002 GO_REF:0000117 RGD:1359026 |
NCBI chr 5:79,111,809...79,132,288
Ensembl chr 5:79,111,809...79,132,288
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G |
BHMT2 |
betaine--homocysteine S-methyltransferase 2 |
involved_in |
IEA |
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InterPro UniProt |
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GO_REF:0000002 GO_REF:0000117 |
NCBI chr 5:79,069,767...79,090,069
Ensembl chr 5:79,069,767...79,090,069
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ENOPH1 |
enolase-phosphatase 1 |
involved_in |
IEA |
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UniProt |
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GO_REF:0000043 |
NCBI chr 4:82,430,590...82,461,177
Ensembl chr 4:82,430,590...82,461,177
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G |
MRI1 |
methylthioribose-1-phosphate isomerase 1 |
involved_in |
IEA |
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UniProt |
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GO_REF:0000043 |
NCBI chr19:13,764,522...13,774,282
Ensembl chr19:13,764,522...13,774,282
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MTHFD1 |
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 |
involved_in |
IMP |
(PMID:25633902) |
BHF-UCL |
PMID:25633902 |
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NCBI chr14:64,388,353...64,460,025
Ensembl chr14:64,388,031...64,463,457
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G |
MTHFD2L |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like |
involved_in |
IEA |
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UniProt |
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GO_REF:0000043 |
NCBI chr 4:74,114,560...74,303,099
Ensembl chr 4:74,114,174...74,303,099
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MTHFR |
methylenetetrahydrofolate reductase |
involved_in acts_upstream_of_or_within |
IBA ISO |
(PMID:15217352) |
GO_Central MGI |
PMID:15217352 |
GO_REF:0000033 |
NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
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MTR |
5-methyltetrahydrofolate-homocysteine methyltransferase |
involved_in acts_upstream_of_or_within |
ISO IMP IEA IBA |
(PMID:23825108) (PMID:11158293) |
RGD BHF-UCL UniProt InterPro GO_Central Ensembl MGI |
PMID:11158293 PMID:11730351 PMID:15845641 PMID:23825108 |
GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117 RGD:1359026 RGD:1601423 |
NCBI chr 1:236,795,281...236,903,981
Ensembl chr 1:236,795,260...236,921,278
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MTRR |
5-methyltetrahydrofolate-homocysteine methyltransferase reductase |
involved_in |
IDA IBA IEA |
(PMID:11466310) |
BHF-UCL GO_Central UniProt |
PMID:11466310 |
GO_REF:0000033 GO_REF:0000043 |
NCBI chr 5:7,850,859...7,901,113
Ensembl chr 5:7,851,186...7,906,025
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MAT1A |
methionine adenosyltransferase 1A |
involved_in |
IMP |
(PMID:10677294) |
UniProt |
PMID:10677294 |
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NCBI chr10:80,271,820...80,289,658
Ensembl chr10:80,271,820...80,289,658
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G |
ADI1 |
acireductone dioxygenase 1 |
involved_in |
IBA |
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GO_Central |
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GO_REF:0000033 |
NCBI chr 2:3,497,366...3,519,531
Ensembl chr 2:3,497,366...3,519,531
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GNMT |
glycine N-methyltransferase |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:17937387) |
Ensembl MGI |
PMID:17937387 |
GO_REF:0000107 |
NCBI chr 6:42,960,754...42,963,880
Ensembl chr 6:42,960,754...42,963,880
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MSRA |
methionine sulfoxide reductase A |
involved_in |
TAS |
(PMID:10452521) |
PINC |
PMID:10452521 |
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NCBI chr 8:10,054,292...10,428,891
Ensembl chr 8:10,054,292...10,428,891
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G |
MTHFD1 |
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 |
involved_in |
ISS IEA |
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BHF-UCL Ensembl |
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GO_REF:0000024 GO_REF:0000107 |
NCBI chr14:64,388,353...64,460,025
Ensembl chr14:64,388,031...64,463,457
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MTHFR |
methylenetetrahydrofolate reductase |
involved_in |
IGI IEA |
(PMID:10551815) |
BHF-UCL InterPro |
PMID:10551815 |
GO_REF:0000002 |
NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
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MTR |
5-methyltetrahydrofolate-homocysteine methyltransferase |
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ISO |
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RGD |
PMID:21121936 |
RGD:7207080 |
NCBI chr 1:236,795,281...236,903,981
Ensembl chr 1:236,795,260...236,921,278
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SMS |
spermine synthase |
involved_in |
TAS |
(PMID:7546290) |
PINC |
PMID:7546290 |
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NCBI chr X:21,940,709...21,994,837
Ensembl chr X:21,940,709...21,994,837
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THNSL2 |
threonine synthase like 2 |
NOT|acts_upstream_of_or_within |
ISO |
(PMID:17034760) |
MGI |
PMID:17034760 |
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NCBI chr 2:88,170,346...88,186,627
Ensembl chr 2:88,170,295...88,186,636
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GCAT |
glycine C-acetyltransferase |
involved_in |
IEA |
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InterPro |
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GO_REF:0000002 |
NCBI chr22:37,807,934...37,817,183
Ensembl chr22:37,807,905...37,817,176
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SDS |
serine dehydratase |
involved_in |
IBA |
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GO_Central |
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GO_REF:0000033 |
NCBI chr12:113,392,445...113,403,887
Ensembl chr12:113,392,445...113,426,301
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SDSL |
serine dehydratase like |
involved_in |
IBA |
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GO_Central |
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GO_REF:0000033 |
NCBI chr12:113,422,380...113,438,276
Ensembl chr12:113,422,380...113,438,276
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TDH |
L-threonine dehydrogenase (pseudogene) |
acts_upstream_of_or_within involved_in |
ISO |
(PMID:21896756) (PMID:26492815) (MGI:5905531|PMID:26492815) |
MGI UniProt |
PMID:21896756 PMID:26492815 |
MGI:5905531 |
NCBI chr 8:11,339,637...11,368,452
Ensembl chr 8:11,339,637...11,368,452 Ensembl chr 8:11,339,637...11,368,452
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G |
PHGDH |
phosphoglycerate dehydrogenase |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:19114063) |
Ensembl MGI |
PMID:19114063 |
GO_REF:0000107 |
NCBI chr 1:119,711,934...119,744,215
Ensembl chr 1:119,648,411...119,744,218
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Term paths to the root
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