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ONTOLOGY REPORT - ANNOTATIONS

Term:aspartate family amino acid metabolic process
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Accession:GO:0009066 term browser browse the term
Definition:The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
Synonyms:exact_synonym: aspartate family amino acid metabolism

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'de novo' L-methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine--homocysteine S-methyltransferase involved_in ISO (PMID:10529246) UniProt PMID:10529246 NCBI chrNW_004955425:21,992,219...22,009,389
Ensembl chrNW_004955425:21,991,665...22,009,855 		JBrowse link
asparagine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspg asparaginase involved_in ISO PMID:9575212 UniProt PMID:9575212 RGD:1299414 NCBI chrNW_004955538:2,765,215...2,785,390
Ensembl chrNW_004955538:2,765,104...2,785,526 		JBrowse link
G Nit2 nitrilase family member 2 involved_in ISO (PMID:22674578) BHF-UCL PMID:22674578 NCBI chrNW_004955427:1,856,794...1,867,545
Ensembl chrNW_004955427:1,856,794...1,866,596 		JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within ISO (PMID:4193185) MGI PMID:4193185 NCBI chrNW_004955507:5,346,937...5,370,072
Ensembl chrNW_004955507:5,346,838...5,370,072 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (PMID:4193185) MGI PMID:4193185 NCBI chrNW_004955433:16,121,795...16,145,129
Ensembl chrNW_004955433:16,122,824...16,145,113 		JBrowse link
aspartate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddo D-aspartate oxidase involved_in ISO (PMID:9163533) UniProt PMID:9163533 NCBI chrNW_004955411:35,142,415...35,163,234
Ensembl chrNW_004955411:35,143,735...35,163,276 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 involved_in ISO (PMID:2241899) UniProt PMID:2241899 NCBI chrNW_004955507:5,346,937...5,370,072
Ensembl chrNW_004955507:5,346,838...5,370,072 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 involved_in ISO (PMID:2567216) UniProt PMID:2567216 NCBI chrNW_004955433:16,121,795...16,145,129
Ensembl chrNW_004955433:16,122,824...16,145,113 		JBrowse link
aspartate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adss1 adenylosuccinate synthase 1 ISO RGD PMID:3759987 RGD:5135303 NCBI chrNW_004955538:3,179,299...3,196,251
Ensembl chrNW_004955538:3,179,299...3,196,251 		JBrowse link
G Adss2 adenylosuccinate synthase 2 ISO RGD PMID:71897 RGD:5135533 NCBI chrNW_004955406:7,684,979...7,715,179
Ensembl chrNW_004955406:7,683,596...7,715,616 		JBrowse link
G Aspa aspartoacylase involved_in ISO (PMID:28077719) MGI PMID:28077719 NCBI chrNW_004955467:13,277,014...13,332,658
Ensembl chrNW_004955467:13,280,254...13,316,114 		JBrowse link
G Ass1 argininosuccinate synthase 1 involved_in ISO (PMID:7977368) BHF-UCL PMID:7977368 NCBI chrNW_004955513:443,372...485,190
Ensembl chrNW_004955513:445,462...485,190 		JBrowse link
G Ddo D-aspartate oxidase acts_upstream_of_or_within ISO (PMID:16525061) MGI PMID:16525061 NCBI chrNW_004955411:35,142,415...35,163,234
Ensembl chrNW_004955411:35,143,735...35,163,276 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 ISO RGD PMID:2837211 RGD:2289377 NCBI chrNW_004955507:5,346,937...5,370,072
Ensembl chrNW_004955507:5,346,838...5,370,072 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 ISO RGD PMID:12686151 RGD:2289396 NCBI chrNW_004955433:16,121,795...16,145,129
Ensembl chrNW_004955433:16,122,824...16,145,113 		JBrowse link
G Nat8l N-acetyltransferase 8 like involved_in ISO (PMID:28077719) MGI PMID:28077719 NCBI chrNW_004955514:1,207,310...1,213,732 JBrowse link
glutamate catabolic process to aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within ISO (PMID:4193185) MGI PMID:4193185 NCBI chrNW_004955507:5,346,937...5,370,072
Ensembl chrNW_004955507:5,346,838...5,370,072 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (PMID:4193185) MGI PMID:4193185 NCBI chrNW_004955433:16,121,795...16,145,129
Ensembl chrNW_004955433:16,122,824...16,145,113 		JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 involved_in ISO (PMID:10934207) CAFA PMID:10934207 NCBI chrNW_004955474:11,392,163...11,473,918
Ensembl chrNW_004955474:11,392,163...11,475,508 		JBrowse link
G Plod3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 involved_in ISO (MGI:6202004|PMID:16447251) UniProt PMID:16447251 MGI:6202004 NCBI chrNW_004955456:16,082,424...16,090,773
Ensembl chrNW_004955456:16,082,437...16,093,389 		JBrowse link
L-asparagine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in ISO (PMID:11960987) UniProt PMID:11960987 NCBI chrNW_004955413:25,406,589...25,408,727
Ensembl chrNW_004955413:25,406,589...25,412,218 		JBrowse link
L-lysine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase acts_upstream_of_or_within ISO (PMID:10567240) MGI PMID:10567240 NCBI chrNW_004955479:3,746,003...3,805,835
Ensembl chrNW_004955479:3,742,757...3,814,338 		JBrowse link
L-lysine catabolic process to acetyl-CoA via L-pipecolate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pipox pipecolic acid and sarcosine oxidase involved_in ISO (PMID:10642506) UniProt PMID:10642506 NCBI chrNW_004955481:4,128,503...4,225,027
Ensembl chrNW_004955481:4,128,509...4,143,334 		JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine--homocysteine S-methyltransferase involved_in ISO (PMID:18230605) BHF-UCL PMID:18230605 NCBI chrNW_004955425:21,992,219...22,009,389
Ensembl chrNW_004955425:21,991,665...22,009,855 		JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in ISO (PMID:15938715) UniProt PMID:15938715 NCBI chrNW_004955487:3,816,428...3,822,663
Ensembl chrNW_004955487:3,816,428...3,822,663 		JBrowse link
G Apip APAF1 interacting protein involved_in ISO (PMID:22837397), (PMID:23285211) UniProt PMID:22837397 PMID:23285211 NCBI chrNW_004955422:11,405,721...11,426,700
Ensembl chrNW_004955422:11,405,721...11,429,146 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in ISO (PMID:15843022) UniProt PMID:15843022 NCBI chrNW_004955433:6,522,663...6,549,352
Ensembl chrNW_004955433:6,522,663...6,549,352 		JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine--homocysteine S-methyltransferase acts_upstream_of_or_within ISO (PMID:15217352) RGD
MGI		 PMID:15217352 PMID:15845641 RGD:1359026 NCBI chrNW_004955425:21,992,219...22,009,389
Ensembl chrNW_004955425:21,991,665...22,009,855 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) BHF-UCL PMID:25633902 NCBI chrNW_004955466:5,422,141...5,485,773
Ensembl chrNW_004955466:5,420,702...5,485,773 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase acts_upstream_of_or_within ISO (PMID:15217352) MGI PMID:15217352 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase acts_upstream_of_or_within
involved_in		 ISO (PMID:11158293)
PMID:20424322
(PMID:23825108)		 RGD
MGI
BHF-UCL		 PMID:11158293 PMID:11730351 PMID:15845641 PMID:20424322 PMID:23825108 RGD:10054082 RGD:1359026 RGD:1601423 NCBI chrNW_004955492:3,372,915...3,474,173
Ensembl chrNW_004955492:3,376,512...3,474,180 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (PMID:11466310)
(PMID:17369066)
(MGI:3710265|PMID:17369066)		 BHF-UCL PMID:11466310 PMID:17369066 MGI:3710265 NCBI chrNW_004955504:5,412,290...5,435,409
Ensembl chrNW_004955504:5,413,586...5,435,645 		JBrowse link
methionine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mat1a methionine adenosyltransferase 1A involved_in ISO (PMID:10677294) UniProt PMID:10677294 NCBI chrNW_004955510:283,860...300,991
Ensembl chrNW_004955510:281,331...300,985 		JBrowse link
methionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnmt glycine N-methyltransferase acts_upstream_of_or_within ISO (PMID:17937387) MGI PMID:17937387 NCBI chrNW_004955437:8,944,288...8,946,642
Ensembl chrNW_004955437:8,944,047...8,946,642 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (MGI:5621260|PMID:23190757)
(PMID:23190757)		 BHF-UCL PMID:23190757 MGI:5621260 NCBI chrNW_004955466:5,422,141...5,485,773
Ensembl chrNW_004955466:5,420,702...5,485,773 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in ISO (PMID:10551815) BHF-UCL PMID:10551815 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:21121936 RGD:7207080 NCBI chrNW_004955492:3,372,915...3,474,173
Ensembl chrNW_004955492:3,376,512...3,474,180 		JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thnsl2 threonine synthase like 2 NOT|acts_upstream_of_or_within ISO (PMID:17034760) MGI PMID:17034760 NCBI chrNW_004955424:526,967...543,603
Ensembl chrNW_004955424:526,602...543,603 		JBrowse link
threonine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phgdh phosphoglycerate dehydrogenase acts_upstream_of_or_within ISO (PMID:19114063) MGI PMID:19114063 NCBI chrNW_004955435:22,757,473...22,803,123
Ensembl chrNW_004955435:22,757,454...22,803,123 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12533
    cellular process 11968
      metabolic process 7959
        primary metabolic process 7010
          amino acid metabolic process 209
            proteinogenic amino acid metabolic process 114
              aspartate family amino acid metabolic process 27
                L-lysine metabolic process + 2
                asparagine metabolic process + 3
                aspartate family amino acid biosynthetic process + 13
                aspartate family amino acid catabolic process + 6
                aspartate metabolic process + 8
                hydroxylysine metabolic process + 2
                methionine metabolic process + 10
                threonine metabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 12533
    cellular process 11968
      metabolic process 7959
        small molecule metabolic process 1316
          organic acid metabolic process 678
            oxoacid metabolic process 674
              carboxylic acid metabolic process 666
                alpha-amino acid metabolic process 157
                  L-amino acid metabolic process 130
                    aspartate family amino acid metabolic process 27
                      L-lysine metabolic process + 2
                      asparagine metabolic process + 3
                      aspartate family amino acid biosynthetic process + 13
                      aspartate family amino acid catabolic process + 6
                      aspartate metabolic process + 8
                      hydroxylysine metabolic process + 2
                      methionine metabolic process + 10
                      threonine metabolic process + 2
paths to the root