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ONTOLOGY REPORT - ANNOTATIONS


Term:aspartate family amino acid metabolic process
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Accession:GO:0009066 term browser browse the term
Definition:The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
Synonyms:exact_synonym: aspartate family amino acid metabolism


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'de novo' L-methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine--homocysteine S-methyltransferase involved_in ISO (PMID:10529246) UniProt PMID:10529246 NCBI chrNW_004955425:21,992,219...22,009,389
Ensembl chrNW_004955425:21,991,665...22,009,855
JBrowse link
asparagine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspg asparaginase involved_in ISO PMID:9575212 UniProt PMID:9575212 RGD:1299414 NCBI chrNW_004955538:2,765,215...2,785,390
Ensembl chrNW_004955538:2,765,104...2,785,526
JBrowse link
G Nit2 nitrilase family member 2 involved_in ISO (PMID:22674578) BHF-UCL PMID:22674578 NCBI chrNW_004955427:1,856,794...1,867,545
Ensembl chrNW_004955427:1,856,794...1,866,596
JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) MGI PMID:4193185 MGI:53641 NCBI chrNW_004955507:5,346,937...5,370,072
Ensembl chrNW_004955507:5,346,838...5,370,072
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) MGI PMID:4193185 MGI:53641 NCBI chrNW_004955433:16,121,795...16,145,129
Ensembl chrNW_004955433:16,122,824...16,145,113
JBrowse link
aspartate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddo D-aspartate oxidase involved_in ISO (PMID:9163533) UniProt PMID:9163533 NCBI chrNW_004955411:35,142,415...35,163,234
Ensembl chrNW_004955411:35,143,735...35,163,276
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 involved_in ISO (PMID:2241899) UniProt PMID:2241899 NCBI chrNW_004955507:5,346,937...5,370,072
Ensembl chrNW_004955507:5,346,838...5,370,072
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 involved_in ISO (PMID:2567216) UniProt PMID:2567216 NCBI chrNW_004955433:16,121,795...16,145,129
Ensembl chrNW_004955433:16,122,824...16,145,113
JBrowse link
aspartate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adss1 adenylosuccinate synthase 1 ISO RGD PMID:3759987 RGD:5135303 NCBI chrNW_004955538:3,179,299...3,196,251
Ensembl chrNW_004955538:3,179,299...3,196,251
JBrowse link
G Adss2 adenylosuccinate synthase 2 ISO RGD PMID:71897 RGD:5135533 NCBI chrNW_004955406:7,684,979...7,715,179
Ensembl chrNW_004955406:7,683,596...7,715,616
JBrowse link
G Aspa aspartoacylase involved_in ISO (MGI:5819291|PMID:28077719) MGI PMID:28077719 MGI:5819291 NCBI chrNW_004955467:13,277,014...13,332,658
Ensembl chrNW_004955467:13,280,254...13,316,114
JBrowse link
G Ass1 argininosuccinate synthase 1 involved_in ISO (PMID:7977368) BHF-UCL PMID:7977368 NCBI chrNW_004955513:443,372...485,190
Ensembl chrNW_004955513:445,462...485,190
JBrowse link
G Ddo D-aspartate oxidase acts_upstream_of_or_within ISO (MGI:3617951|PMID:16525061) MGI PMID:16525061 MGI:3617951 NCBI chrNW_004955411:35,142,415...35,163,234
Ensembl chrNW_004955411:35,143,735...35,163,276
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 ISO RGD PMID:2837211 RGD:2289377 NCBI chrNW_004955507:5,346,937...5,370,072
Ensembl chrNW_004955507:5,346,838...5,370,072
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 ISO RGD PMID:12686151 RGD:2289396 NCBI chrNW_004955433:16,121,795...16,145,129
Ensembl chrNW_004955433:16,122,824...16,145,113
JBrowse link
G Nat8l N-acetyltransferase 8 like involved_in ISO (MGI:5819291|PMID:28077719) MGI PMID:28077719 MGI:5819291 NCBI chrNW_004955514:1,207,310...1,213,732 JBrowse link
glutamate catabolic process to aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) MGI PMID:4193185 MGI:53641 NCBI chrNW_004955507:5,346,937...5,370,072
Ensembl chrNW_004955507:5,346,838...5,370,072
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) MGI PMID:4193185 MGI:53641 NCBI chrNW_004955433:16,121,795...16,145,129
Ensembl chrNW_004955433:16,122,824...16,145,113
JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 involved_in ISO (PMID:10934207) CAFA PMID:10934207 NCBI chrNW_004955474:11,392,163...11,473,918
Ensembl chrNW_004955474:11,392,163...11,475,508
JBrowse link
G Plod3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 involved_in ISO (MGI:6202004|PMID:16447251) UniProt PMID:16447251 MGI:6202004 NCBI chrNW_004955456:16,082,424...16,090,773
Ensembl chrNW_004955456:16,082,437...16,093,389
JBrowse link
L-asparagine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in ISO (PMID:11960987) UniProt PMID:11960987 NCBI chrNW_004955413:25,406,589...25,408,727
Ensembl chrNW_004955413:25,406,589...25,412,218
JBrowse link
L-lysine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase acts_upstream_of_or_within ISO (MGI:1350812|PMID:10567240) MGI PMID:10567240 MGI:1350812 NCBI chrNW_004955479:3,746,003...3,805,835
Ensembl chrNW_004955479:3,742,757...3,814,338
JBrowse link
L-lysine catabolic process to acetyl-CoA via L-pipecolate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pipox pipecolic acid and sarcosine oxidase involved_in ISO (PMID:10642506) UniProt PMID:10642506 NCBI chrNW_004955481:4,128,503...4,225,027
Ensembl chrNW_004955481:4,128,509...4,143,334
JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine--homocysteine S-methyltransferase involved_in ISO (PMID:18230605) BHF-UCL PMID:18230605 NCBI chrNW_004955425:21,992,219...22,009,389
Ensembl chrNW_004955425:21,991,665...22,009,855
JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in ISO (PMID:15938715) UniProt PMID:15938715 NCBI chrNW_004955487:3,816,428...3,822,663
Ensembl chrNW_004955487:3,816,428...3,822,663
JBrowse link
G Apip APAF1 interacting protein involved_in ISO (PMID:22837397), (PMID:23285211) UniProt PMID:22837397 PMID:23285211 NCBI chrNW_004955422:11,405,721...11,426,700
Ensembl chrNW_004955422:11,405,721...11,429,146
JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in ISO (PMID:15843022) UniProt PMID:15843022 NCBI chrNW_004955433:6,522,663...6,549,352
Ensembl chrNW_004955433:6,522,663...6,549,352
JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine--homocysteine S-methyltransferase acts_upstream_of_or_within ISO (MGI:3510291|PMID:15217352) RGD
MGI
PMID:15217352 PMID:15845641 MGI:3510291 RGD:1359026 NCBI chrNW_004955425:21,992,219...22,009,389
Ensembl chrNW_004955425:21,991,665...22,009,855
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) BHF-UCL PMID:25633902 NCBI chrNW_004955466:5,422,141...5,485,773
Ensembl chrNW_004955466:5,420,702...5,485,773
JBrowse link
G Mthfr methylenetetrahydrofolate reductase acts_upstream_of_or_within ISO (MGI:3510291|PMID:15217352) MGI PMID:15217352 MGI:3510291 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in
acts_upstream_of_or_within
ISO PMID:20424322
(MGI:1930456|PMID:11158293)
(PMID:23825108)
RGD
BHF-UCL
MGI
PMID:11158293 PMID:11730351 PMID:15845641 PMID:20424322 PMID:23825108 MGI:1930456 RGD:10054082 RGD:1359026 RGD:1601423 NCBI chrNW_004955492:3,372,915...3,474,173
Ensembl chrNW_004955492:3,376,512...3,474,180
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (PMID:11466310)
(MGI:3710265|PMID:17369066)
BHF-UCL PMID:11466310 PMID:17369066 MGI:3710265 NCBI chrNW_004955504:5,412,290...5,435,409
Ensembl chrNW_004955504:5,413,586...5,435,645
JBrowse link
methionine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mat1a methionine adenosyltransferase 1A involved_in ISO (PMID:10677294) UniProt PMID:10677294 NCBI chrNW_004955510:283,860...300,991
Ensembl chrNW_004955510:281,331...300,985
JBrowse link
methionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnmt glycine N-methyltransferase acts_upstream_of_or_within ISO (MGI:3842675|PMID:17937387) MGI PMID:17937387 MGI:3842675 NCBI chrNW_004955437:8,944,288...8,946,642
Ensembl chrNW_004955437:8,944,047...8,946,642
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (MGI:5621260|PMID:23190757) BHF-UCL PMID:23190757 MGI:5621260 NCBI chrNW_004955466:5,422,141...5,485,773
Ensembl chrNW_004955466:5,420,702...5,485,773
JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in ISO (PMID:10551815) BHF-UCL PMID:10551815 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:21121936 RGD:7207080 NCBI chrNW_004955492:3,372,915...3,474,173
Ensembl chrNW_004955492:3,376,512...3,474,180
JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thnsl2 threonine synthase like 2 NOT|acts_upstream_of_or_within ISO (MGI:3690523|PMID:17034760) MGI PMID:17034760 MGI:3690523 NCBI chrNW_004955424:526,967...543,603
Ensembl chrNW_004955424:526,602...543,603
JBrowse link
threonine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phgdh phosphoglycerate dehydrogenase acts_upstream_of_or_within ISO (MGI:3835979|PMID:19114063) MGI PMID:19114063 MGI:3835979 NCBI chrNW_004955435:22,757,473...22,803,123
Ensembl chrNW_004955435:22,757,454...22,803,123
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12307
    metabolic process 7442
      primary metabolic process 6417
        amino acid metabolic process 197
          proteinogenic amino acid metabolic process 99
            aspartate family amino acid metabolic process 27
              L-lysine metabolic process + 2
              asparagine metabolic process + 3
              aspartate family amino acid biosynthetic process + 13
              aspartate family amino acid catabolic process + 6
              aspartate metabolic process + 8
              hydroxylysine metabolic process + 2
              methionine metabolic process + 10
              threonine metabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 12307
    cellular process 11488
      cellular metabolic process 6653
        organic acid metabolic process 660
          oxoacid metabolic process 656
            carboxylic acid metabolic process 648
              alpha-amino acid metabolic process 147
                L-amino acid metabolic process 107
                  aspartate family amino acid metabolic process 27
                    L-lysine metabolic process + 2
                    asparagine metabolic process + 3
                    aspartate family amino acid biosynthetic process + 13
                    aspartate family amino acid catabolic process + 6
                    aspartate metabolic process + 8
                    hydroxylysine metabolic process + 2
                    methionine metabolic process + 10
                    threonine metabolic process + 2
paths to the root