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ONTOLOGY REPORT - ANNOTATIONS

Term:aspartate family amino acid metabolic process
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Accession:GO:0009066 term browser browse the term
Definition:The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
Synonyms:exact_synonym: aspartate family amino acid metabolism


show annotations for term's descendants           Sort by:
aspartate family amino acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASPG asparaginase involved_in IEA UniProt GO_REF:0000117 NCBI chr14:84,711,400...84,739,769
Ensembl chr14:104,517,278...104,544,589 		JBrowse link
'de novo' L-methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHMT betaine--homocysteine S-methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:36,181,183...36,201,833
Ensembl chr 5:36,670,854...36,728,993 		JBrowse link
asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASNS asparagine synthetase (glutamine-hydrolyzing) involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:2573597) RGD
TreeGrafter
InterPro
UniProt
Ensembl
MGI		 PMID:2573597 PMID:2887559 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 RGD:2316002 NCBI chr 7:89,811,363...89,831,733
Ensembl chr 7:103,392,540...103,413,046 		JBrowse link
G ASNSD1 asparagine synthetase domain containing 1 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr2B:76,967,753...76,977,139
Ensembl chr2B:194,887,530...194,896,927 		JBrowse link
G LOC100981233 asparagine synthetase [glutamine-hydrolyzing]-like involved_in IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr 8:43,010,778...43,045,817 JBrowse link
asparagine catabolic process via L-aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASRGL1 asparaginase and isoaspartyl peptidase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:12753071 MGI
TreeGrafter
Ensembl		 PMID:12753071 GO_REF:0000107 GO_REF:0000118 RGD:1299508 NCBI chr11:57,700,104...57,750,371
Ensembl chr11:61,056,817...61,107,485 		JBrowse link
asparagine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASPG asparaginase involved_in ISO PMID:9575212 UniProt PMID:9575212 RGD:1299414 NCBI chr14:84,711,400...84,739,769
Ensembl chr14:104,517,278...104,544,589 		JBrowse link
G NIT2 nitrilase family member 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:97,427,470...97,448,354
Ensembl chr 3:104,109,804...104,130,535 		JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GOT1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:4193185) Ensembl
TreeGrafter
MGI		 PMID:4193185 GO_REF:0000107 GO_REF:0000118 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178 		JBrowse link
G GOT1L1 glutamic-oxaloacetic transaminase 1 like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:37,234,593...37,241,464
Ensembl chr 8:34,412,465...34,418,343 		JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (PMID:4193185) MGI PMID:4193185 NCBI chr16:38,995,770...39,022,750
Ensembl chr16:58,120,781...58,147,378 		JBrowse link
aspartate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDO D-aspartate oxidase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:108,199,861...108,223,844
Ensembl chr 6:112,269,271...112,292,980 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178 		JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:38,995,770...39,022,750
Ensembl chr16:58,120,781...58,147,378 		JBrowse link
aspartate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADSS1 adenylosuccinate synthase 1 ISO RGD PMID:3759987 RGD:5135303 Ensembl chr14:105,169,769...105,190,333 JBrowse link
G ADSS2 adenylosuccinate synthase 2 ISO RGD PMID:71897 RGD:5135533 NCBI chr 1:220,020,480...220,063,658
Ensembl chr 1:225,401,544...225,444,984 		JBrowse link
G ASPA aspartoacylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:3,492,304...3,517,882
Ensembl chr17:3,522,858...3,546,279 		JBrowse link
G ASS1 argininosuccinate synthase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:101,569,442...101,625,899
Ensembl chr 9:130,219,993...130,276,036 		JBrowse link
G DDO D-aspartate oxidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16525061) Ensembl
MGI		 PMID:16525061 GO_REF:0000107 NCBI chr 6:108,199,861...108,223,844
Ensembl chr 6:112,269,271...112,292,980 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 ISO RGD PMID:2837211 RGD:2289377 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178 		JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 ISO RGD PMID:12686151 RGD:2289396 NCBI chr16:38,995,770...39,022,750
Ensembl chr16:58,120,781...58,147,378 		JBrowse link
G NAT8L N-acetyltransferase 8 like involved_in ISO (PMID:28077719) MGI PMID:28077719 NCBI chr 4:2,201,326...2,211,302 JBrowse link
glutamate catabolic process to aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GOT1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:4193185) Ensembl
MGI		 PMID:4193185 GO_REF:0000107 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178 		JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (PMID:4193185) MGI PMID:4193185 NCBI chr16:38,995,770...39,022,750
Ensembl chr16:58,120,781...58,147,378 		JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:143,091,833...143,181,831
Ensembl chr 3:150,675,424...150,764,939 		JBrowse link
G PLOD3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:93,347,335...93,358,921
Ensembl chr 7:106,587,858...106,599,605 		JBrowse link
L-asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASNS asparagine synthetase (glutamine-hydrolyzing) involved_in IEA UniProt GO_REF:0000041 NCBI chr 7:89,811,363...89,831,733
Ensembl chr 7:103,392,540...103,413,046 		JBrowse link
L-asparagine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 involved_in ISO (PMID:11960987) UniProt PMID:11960987 NCBI chr22:20,426,743...20,428,892
Ensembl chr22:38,248,094...38,249,249 		JBrowse link
L-lysine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AASS aminoadipate-semialdehyde synthase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10567240) Ensembl
MGI		 PMID:10567240 GO_REF:0000107 NCBI chr 7:114,084,792...114,155,558
Ensembl chr 7:126,769,655...126,840,346 		JBrowse link
L-lysine catabolic process to acetyl-CoA via L-pipecolate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIPOX pipecolic acid and sarcosine oxidase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:27,717,083...27,820,776
Ensembl chr17:28,225,831...28,240,210 		JBrowse link
L-lysine catabolic process to acetyl-CoA via saccharopine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AASS aminoadipate-semialdehyde synthase involved_in IEA UniProt GO_REF:0000041 NCBI chr 7:114,084,792...114,155,558
Ensembl chr 7:126,769,655...126,840,346 		JBrowse link
G DLST dihydrolipoamide S-succinyltransferase involved_in IEA UniProt GO_REF:0000041 NCBI chr14:55,433,358...55,455,876
Ensembl chr14:74,278,128...74,300,133 		JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHMT betaine--homocysteine S-methyltransferase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:36,181,183...36,201,833
Ensembl chr 5:36,670,854...36,728,993 		JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:36,223,429...36,242,187
Ensembl chr 5:36,670,854...36,728,993 		JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADI1 acireductone dioxygenase 1 involved_in IEA Ensembl
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000104 GO_REF:0000107 NCBI chr2A:3,509,162...3,538,064
Ensembl chr2A:3,430,158...3,458,248 		JBrowse link
G APIP APAF1 interacting protein involved_in IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000118 NCBI chr11:34,855,437...34,889,486
Ensembl chr11:34,730,671...34,764,732 		JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt
TreeGrafter
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:41,741,072...41,771,150
Ensembl chr 4:47,591,329...47,621,357 		JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt
TreeGrafter		 GO_REF:0000041 GO_REF:0000118 NCBI chr19:13,327,569...13,336,286
Ensembl chr19:14,060,859...14,067,222 		JBrowse link
G MTAP methylthioadenosine phosphorylase involved_in IEA UniProt
TreeGrafter		 GO_REF:0000041 GO_REF:0000104 GO_REF:0000118 NCBI chr 9:21,637,543...21,769,698
Ensembl chr 9:22,266,376...22,382,218 		JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APIP APAF1 interacting protein involved_in IEA UniProt GO_REF:0000104 NCBI chr11:34,855,437...34,889,486
Ensembl chr11:34,730,671...34,764,732 		JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr 4:41,741,072...41,771,150
Ensembl chr 4:47,591,329...47,621,357 		JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr19:13,327,569...13,336,286
Ensembl chr19:14,060,859...14,067,222 		JBrowse link
lysine biosynthetic process via aminoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:100,969,185...100,990,296
Ensembl chr11:104,452,913...104,474,063 		JBrowse link
G AASS aminoadipate-semialdehyde synthase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:114,084,792...114,155,558
Ensembl chr 7:126,769,655...126,840,346 		JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADI1 acireductone dioxygenase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr2A:3,509,162...3,538,064
Ensembl chr2A:3,430,158...3,458,248 		JBrowse link
G APIP APAF1 interacting protein involved_in IEA UniProt GO_REF:0000043 NCBI chr11:34,855,437...34,889,486
Ensembl chr11:34,730,671...34,764,732 		JBrowse link
G BHMT betaine--homocysteine S-methyltransferase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15217352) RGD
MGI
UniProt
InterPro		 PMID:15217352 PMID:15845641 GO_REF:0000002 GO_REF:0000117 RGD:1359026 NCBI chr 5:36,181,183...36,201,833
Ensembl chr 5:36,670,854...36,728,993 		JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000117 NCBI chr 5:36,223,429...36,242,187
Ensembl chr 5:36,670,854...36,728,993 		JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:41,741,072...41,771,150
Ensembl chr 4:47,591,329...47,621,357 		JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr19:13,327,569...13,336,286
Ensembl chr19:14,060,859...14,067,222 		JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:44,969,573...45,041,296
Ensembl chr14:63,223,484...63,293,881 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15217352) MGI
TreeGrafter		 PMID:15217352 GO_REF:0000118 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:11158293) RGD
TreeGrafter
MGI
UniProt
Ensembl
InterPro		 PMID:11158293 PMID:11730351 PMID:15845641 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 RGD:1359026 RGD:1601423 NCBI chr 1:212,353,195...212,463,304
Ensembl chr 1:217,358,050...217,460,946 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:8,195,868...8,228,071
Ensembl chr 5:8,017,403...8,049,322 		JBrowse link
methionine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAT1A methionine adenosyltransferase 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:76,677,815...76,697,512
Ensembl chr10:80,280,063...80,298,291 		JBrowse link
methionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADI1 acireductone dioxygenase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:3,509,162...3,538,064
Ensembl chr2A:3,430,158...3,458,248 		JBrowse link
G GNMT glycine N-methyltransferase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17937387) Ensembl
MGI		 PMID:17937387 GO_REF:0000107 NCBI chr 6:42,550,631...42,554,385
Ensembl chr 6:43,846,560...43,849,679 		JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (MGI:5621260|PMID:23190757)
(PMID:23190757)		 BHF-UCL PMID:23190757 MGI:5621260 NCBI chr14:44,969,573...45,041,296
Ensembl chr14:63,223,484...63,293,881 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:21121936 RGD:7207080 NCBI chr 1:212,353,195...212,463,304
Ensembl chr 1:217,358,050...217,460,946 		JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G THNSL2 threonine synthase like 2 NOT|acts_upstream_of_or_within ISO (PMID:17034760) MGI PMID:17034760 NCBI chr2A:87,303,022...87,319,494
Ensembl chr2A:89,212,442...89,228,446 		JBrowse link
threonine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCAT glycine C-acetyltransferase involved_in IEA InterPro GO_REF:0000002 NCBI chr22:18,722,886...18,731,963
Ensembl chr22:36,554,067...36,563,429 		JBrowse link
G LOC100990410 L-threonine 3-dehydrogenase, mitochondrial involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:7,837,080...7,855,179 JBrowse link
G SDS serine dehydratase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:110,995,164...111,006,668
Ensembl chr12:114,377,650...114,388,839 		JBrowse link
G SDSL serine dehydratase like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:111,024,957...111,040,900
Ensembl chr12:114,406,738...114,422,347 		JBrowse link
threonine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PHGDH phosphoglycerate dehydrogenase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19114063) Ensembl
MGI		 PMID:19114063 GO_REF:0000107 NCBI chr 1:82,803,155...82,835,465
Ensembl chr 1:117,800,843...117,833,462 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16786
    cellular process 16372
      metabolic process 11065
        primary metabolic process 9784
          amino acid metabolic process 292
            proteinogenic amino acid metabolic process 166
              aspartate family amino acid metabolic process 41
                L-lysine metabolic process + 3
                asparagine metabolic process + 7
                aspartate family amino acid biosynthetic process + 22
                aspartate family amino acid catabolic process + 12
                aspartate metabolic process + 9
                hydroxylysine metabolic process + 2
                methionine metabolic process + 13
                threonine metabolic process + 6
Path 2
Term Annotations click to browse term
  biological_process 16786
    cellular process 16372
      metabolic process 11065
        small molecule metabolic process 1682
          organic acid metabolic process 923
            oxoacid metabolic process 916
              carboxylic acid metabolic process 896
                alpha-amino acid metabolic process 215
                  L-amino acid metabolic process 186
                    aspartate family amino acid metabolic process 41
                      L-lysine metabolic process + 3
                      asparagine metabolic process + 7
                      aspartate family amino acid biosynthetic process + 22
                      aspartate family amino acid catabolic process + 12
                      aspartate metabolic process + 9
                      hydroxylysine metabolic process + 2
                      methionine metabolic process + 13
                      threonine metabolic process + 6
paths to the root