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ONTOLOGY REPORT - ANNOTATIONS


Term:aspartate family amino acid metabolic process
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Accession:GO:0009066 term browser browse the term
Definition:The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
Synonyms:exact_synonym: aspartate family amino acid metabolism



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aspartate family amino acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspg asparaginase involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 6:131,176,727...131,196,268
Ensembl chr 6:131,176,874...131,196,268
JBrowse link
'de novo' L-methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IEA
(PMID:10529246)
GO_REF:0000107
RGD
Ensembl
PMID:10529246 GO_REF:0000107 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) involved_in
acts_upstream_of_or_within
IDA
IBA
ISO
GO_REF:0000033
(PMID:2573597)
GO_Central
RGD
PMID:2573597 PMID:2887559 GO_REF:0000033, RGD:2316002 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Asnsd1 asparagine synthetase domain containing 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:48,126,808...48,139,073
Ensembl chr 9:48,126,808...48,139,073
JBrowse link
asparagine catabolic process via L-aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asrgl1 asparaginase and isoaspartyl peptidase 1 involved_in
acts_upstream_of_or_within
ISO
IBA
IDA
(PMID:19839645)
GO_REF:0000033
PMID:12753071
RGD
GO_Central
PMID:19839645 PMID:12753071 PMID:12753071 GO_REF:0000033, RGD:1299508, RGD:1299508 NCBI chr 1:206,006,103...206,027,115
Ensembl chr 1:206,006,109...206,027,108
JBrowse link
asparagine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspg asparaginase involved_in IDA PMID:9575212 UniProt PMID:9575212 RGD:1299414 NCBI chr 6:131,176,727...131,196,268
Ensembl chr 6:131,176,874...131,196,268
JBrowse link
G Nit2 nitrilase family, member 2 involved_in ISO
IBA
IEA
(PMID:22674578)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:22674578 GO_REF:0000033 GO_REF:0000107 NCBI chr11:43,363,839...43,378,713
Ensembl chr11:43,363,985...43,375,024
JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
(PMID:4193185)
GO_REF:0000033
Ensembl
RGD
GO_Central
PMID:4193185 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:64,860,308...64,873,656
Ensembl chr16:64,860,704...64,866,162
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (PMID:4193185) RGD PMID:4193185 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
aspartate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddo D-aspartate oxidase involved_in ISO
IBA
(PMID:9163533)
GO_REF:0000033
RGD
GO_Central
PMID:9163533 GO_REF:0000033 NCBI chr20:44,090,823...44,109,962
Ensembl chr20:44,090,914...44,133,095
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 involved_in ISO
IEA
(PMID:2241899)
GO_REF:0000107
RGD
Ensembl
PMID:2241899 GO_REF:0000107 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 involved_in ISO
IBA
(PMID:2567216)
GO_REF:0000033
RGD
GO_Central
PMID:2567216 GO_REF:0000033 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
aspartate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adss1 adenylosuccinate synthase 1 IDA RGD PMID:3759987 RGD:5135303 NCBI chr 6:131,679,795...131,702,012
Ensembl chr 6:131,679,701...131,701,998
JBrowse link
G Adss2 adenylosuccinate synthase 2 IDA RGD PMID:71897 RGD:5135533 NCBI chr13:89,769,240...89,799,577
Ensembl chr13:89,769,244...89,799,604
JBrowse link
G Aspa aspartoacylase involved_in ISO MGI:2447776 (PMID:28077719) RGD PMID:28077719 NCBI chr10:57,891,704...57,945,267
Ensembl chr10:57,892,104...57,945,272
JBrowse link
G Ass1 argininosuccinate synthase 1 involved_in ISO (PMID:7977368) RGD PMID:7977368 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
JBrowse link
G Ddo D-aspartate oxidase acts_upstream_of_or_within ISO MGI:3625623 (PMID:16525061) RGD PMID:16525061 NCBI chr20:44,090,823...44,109,962
Ensembl chr20:44,090,914...44,133,095
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 involved_in IDA
ISS
GO_REF:0000024 UniProt
RGD
PMID:2837211 GO_REF:0000024, RGD:2289377 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 involved_in IMP
ISS
GO_REF:0000024 UniProt
RGD
PMID:12686151 GO_REF:0000024, RGD:2289396 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Nat8l N-acetyltransferase 8-like involved_in ISO MGI:87914 (PMID:28077719) RGD PMID:28077719 NCBI chr14:76,756,077...76,762,712
Ensembl chr14:76,756,077...76,763,411
JBrowse link
glutamate catabolic process to aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:4193185)
Ensembl
RGD
PMID:4193185 GO_REF:0000107 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (PMID:4193185) RGD PMID:4193185 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 involved_in ISO
IEA
(PMID:10934207)
GO_REF:0000107
RGD
Ensembl
PMID:10934207 GO_REF:0000107 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 involved_in ISO
IEA
(MGI:6202004|PMID:16447251)
GO_REF:0000107
RGD
Ensembl
PMID:16447251 GO_REF:0000107 MGI:6202004 NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960
JBrowse link
L-asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
L-asparagine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in ISO (PMID:11960987) RGD PMID:11960987 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
L-lysine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase acts_upstream_of_or_within ISO (PMID:10567240) RGD PMID:10567240 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
JBrowse link
L-lysine catabolic process to acetyl-CoA via L-pipecolate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pipox pipecolic acid and sarcosine oxidase involved_in ISO
IBA
(PMID:10642506)
GO_REF:0000033
RGD
GO_Central
PMID:10642506 GO_REF:0000033 NCBI chr10:62,769,874...62,783,484
Ensembl chr10:62,769,900...62,782,370
JBrowse link
L-lysine catabolic process to acetyl-CoA via saccharopine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332
JBrowse link
G Aass aminoadipate-semialdehyde synthase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IEA
IBA
(PMID:18230605)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:18230605 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in IEA
ISO
IBA
GO_REF:0000107
(PMID:18230605)
GO_REF:0000033
Ensembl
RGD
GO_Central
PMID:18230605 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475
JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IEA
ISS
ISO
GO_REF:0000041
GO_REF:0000024
(PMID:15938715)
UniProt
RGD
PMID:15938715 GO_REF:0000024 GO_REF:0000041 NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842
JBrowse link
G Apip APAF1 interacting protein involved_in IEA
IBA
ISO
GO_REF:0000041
GO_REF:0000033
(PMID:22837397), (PMID:23285211)
UniProt
GO_Central
RGD
PMID:22837397 PMID:23285211 GO_REF:0000033 GO_REF:0000041 NCBI chr 3:89,431,964...89,458,000
Ensembl chr 3:89,432,037...89,458,340
JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA
IBA
ISO
ISS
GO_REF:0000041
GO_REF:0000033
(PMID:15843022)
GO_REF:0000024
UniProt
GO_Central
RGD
PMID:15843022 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA
IBA
GO_REF:0000041
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000041 NCBI chr19:23,907,327...23,913,721
Ensembl chr19:23,907,335...23,913,320
JBrowse link
G Mtap methylthioadenosine phosphorylase involved_in IEA
IBA
GO_REF:0000041
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000041 NCBI chr 5:103,874,460...103,920,684
Ensembl chr 5:103,873,020...103,939,406
JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:89,431,964...89,458,000
Ensembl chr 3:89,432,037...89,458,340
JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr19:23,907,327...23,913,721
Ensembl chr19:23,907,335...23,913,320
JBrowse link
lysine biosynthetic process via aminoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:1,453,226...1,463,990
Ensembl chr 8:1,452,282...1,463,966
JBrowse link
G Aass aminoadipate-semialdehyde synthase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase acts_upstream_of_or_within IDA
ISO
(PMID:15217352) RGD PMID:15217352 PMID:15845641 RGD:1359026 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO
IEA
(PMID:25633902)
GO_REF:0000107
RGD
Ensembl
PMID:25633902 GO_REF:0000107 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112
JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:2385823 (PMID:15217352)
GO_Central
RGD
PMID:15217352 GO_REF:0000033 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
MGI:2180496 (PMID:11158293)
PMID:20424322
GO_REF:0000033
(PMID:23825108)
RGD
GO_Central
PMID:11158293 PMID:23825108 PMID:15845641 PMID:20424322 PMID:11730351 GO_REF:0000033, RGD:1359026, RGD:10054082, RGD:1601423 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO
IBA
IEA
(PMID:11466310)
GO_REF:0000033
GO_REF:0000043
(MGI:3710265|PMID:17369066)
RGD
GO_Central
UniProt
PMID:11466310 PMID:17369066 GO_REF:0000033 GO_REF:0000043 MGI:3710265 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425
JBrowse link
methionine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mat1a methionine adenosyltransferase 1A involved_in ISO
ISS
(PMID:10677294)
GO_REF:0000024
RGD
UniProt
PMID:10677294 GO_REF:0000024 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274
JBrowse link
methionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842
JBrowse link
G Gnmt glycine N-methyltransferase acts_upstream_of_or_within ISO MGI:3842652 (PMID:17937387) RGD PMID:17937387 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (MGI:5621260|PMID:23190757) RGD PMID:23190757 MGI:5621260 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in ISO UniProtKB:P53128 (PMID:10551815) RGD PMID:10551815 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase IMP RGD PMID:21121936 RGD:7207080 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thnsl2 threonine synthase-like 2 NOT|acts_upstream_of_or_within ISO (PMID:17034760) RGD PMID:17034760 NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017
JBrowse link
threonine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gcat glycine C-acetyltransferase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:110,595,126...110,601,474
Ensembl chr 7:110,595,091...110,601,473
JBrowse link
G Sds serine dehydratase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
JBrowse link
G Tdh L-threonine dehydrogenase involved_in
acts_upstream_of_or_within
ISO
IBA
(MGI:5905531|PMID:26492815)
(PMID:21896756)
GO_REF:0000033
RGD
GO_Central
PMID:21896756 PMID:26492815 GO_REF:0000033 MGI:5905531 NCBI chr15:37,739,823...37,753,365
Ensembl chr15:37,739,823...37,753,365
JBrowse link
G Tha1 threonine aldolase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:103,094,681...103,100,169
Ensembl chr10:103,094,681...103,100,519
JBrowse link
threonine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phgdh phosphoglycerate dehydrogenase acts_upstream_of_or_within ISO MGI:3769591 (PMID:19114063) RGD PMID:19114063 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19872
    metabolic process 11602
      organonitrogen compound metabolic process 5725
        proteinogenic amino acid metabolic process 173
          aspartate family amino acid metabolic process 42
            L-lysine metabolic process + 4
            asparagine metabolic process + 6
            aspartate family amino acid biosynthetic process + 22
            aspartate family amino acid catabolic process + 13
            aspartate metabolic process + 9
            hydroxylysine metabolic process + 2
            methionine metabolic process + 14
            threonine metabolic process + 6
Path 2
Term Annotations click to browse term
  biological_process 19872
    metabolic process 11602
      cellular metabolic process 9669
        organic acid metabolic process 1025
          oxoacid metabolic process 1014
            carboxylic acid metabolic process 999
              alpha-amino acid metabolic process 212
                L-amino acid metabolic process 184
                  aspartate family amino acid metabolic process 42
                    L-lysine metabolic process + 4
                    asparagine metabolic process + 6
                    aspartate family amino acid biosynthetic process + 22
                    aspartate family amino acid catabolic process + 13
                    aspartate metabolic process + 9
                    hydroxylysine metabolic process + 2
                    methionine metabolic process + 14
                    threonine metabolic process + 6
paths to the root