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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA-methyltransferase activity
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Accession:GO:0009008 term browser browse the term
Definition:Catalysis of the transfer of a methyl group to a DNA molecule.
Synonyms:exact_synonym: DNA transmethylase activity;   deoxyribonucleate methylase activity;   deoxyribonucleate methyltransferase activity;   deoxyribonucleic acid methylase activity;   deoxyribonucleic acid methyltransferase activity
 broad_synonym: DNA methylase
 related_synonym: Type II DNA methylase;   deoxyribonucleic acid modification methylase activity
 xref: reactome:R-HSA-5227490 "NoRC:HDAC:DNMT methylates cytosine of the rRNA genes"
 never_in_taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe

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DNA-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936485:19,547,836...19,570,716 JBrowse link
G LOC101971479 DNA (cytosine-5)-methyltransferase 3B-like enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936995:173,828...179,021 JBrowse link
DNA (cytosine-5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 enables ISO
IEA		 RGD
TreeGrafter
RHEA
Ensembl
InterPro
UniProt		 PMID:12473678 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 RGD:1359078 NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936493:6,963,406...7,013,256
Ensembl chrNW_004936493:6,935,386...7,007,610 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta enables ISO (PMID:16543361), (PMID:22133874), (PMID:27841881), (PMID:9662389)
(PMID:17938196)		 MGI PMID:9662389 PMID:16543361 PMID:17938196 PMID:22133874 PMID:27841881 NCBI chrNW_004936485:19,547,836...19,570,716 JBrowse link
G Dnmt3l DNA methyltransferase 3 like NOT|enables ISO (PMID:11934864) MGI PMID:11934864 NCBI chrNW_004936500:143,078...160,318
Ensembl chrNW_004936500:143,078...160,212 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt3b DNA methyltransferase 3 beta enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936485:19,547,836...19,570,716 JBrowse link
G LOC101971479 DNA (cytosine-5)-methyltransferase 3B-like enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936995:173,828...179,021 JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 enables IEA UniProt GO_REF:0000003 NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha enables IEA UniProt GO_REF:0000003 NCBI chrNW_004936493:6,963,406...7,013,256
Ensembl chrNW_004936493:6,935,386...7,007,610 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta enables IEA UniProt GO_REF:0000003 NCBI chrNW_004936485:19,547,836...19,570,716 JBrowse link
G LOC101971479 DNA (cytosine-5)-methyltransferase 3B-like enables IEA UniProt GO_REF:0000003 NCBI chrNW_004936995:173,828...179,021 JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 enables IEA UniProt GO_REF:0000003 NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha enables IEA UniProt GO_REF:0000003 NCBI chrNW_004936493:6,963,406...7,013,256
Ensembl chrNW_004936493:6,935,386...7,007,610 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta enables IEA UniProt GO_REF:0000003 NCBI chrNW_004936485:19,547,836...19,570,716 JBrowse link
G LOC101971479 DNA (cytosine-5)-methyltransferase 3B-like enables IEA UniProt GO_REF:0000003 NCBI chrNW_004936995:173,828...179,021 JBrowse link
site-specific DNA-methyltransferase (adenine-specific) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl4 methyltransferase 4, N6-adenosine enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936672:1,911,109...1,940,897
Ensembl chrNW_004936672:1,910,851...1,941,520 		JBrowse link
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 NOT|enables ISO
IEA		 (PMID:30392959), (PMID:31632689), (PMID:31636962) UniProt
Ensembl		 PMID:30392959 PMID:31632689 PMID:31636962 GO_REF:0000107 NCBI chrNW_004936500:13,086,873...13,099,814
Ensembl chrNW_004936500:13,084,595...13,099,844 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18185
    catalytic activity 5254
      catalytic activity, acting on a nucleic acid 580
        catalytic activity, acting on DNA 237
          DNA-methyltransferase activity 7
            DNA (cytosine-5-)-methyltransferase activity + 5
            site-specific DNA-methyltransferase (adenine-specific) activity 2
            site-specific DNA-methyltransferase (cytosine-N4-specific) activity 0
Path 2
Term Annotations click to browse term
  molecular_function 18185
    catalytic activity 5254
      transferase activity 2123
        transferase activity, transferring one-carbon groups 202
          methyltransferase activity 191
            DNA-methyltransferase activity 7
              DNA (cytosine-5-)-methyltransferase activity + 5
              site-specific DNA-methyltransferase (adenine-specific) activity 2
              site-specific DNA-methyltransferase (cytosine-N4-specific) activity 0
paths to the root