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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA-methyltransferase activity
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Accession:GO:0009008 term browser browse the term
Definition:Catalysis of the transfer of a methyl group to a DNA molecule.
Synonyms:exact_synonym: DNA transmethylase activity;   deoxyribonucleate methylase activity;   deoxyribonucleate methyltransferase activity;   deoxyribonucleic acid methylase activity;   deoxyribonucleic acid methyltransferase activity
 broad_synonym: DNA methylase
 related_synonym: Type II DNA methylase;   deoxyribonucleic acid modification methylase activity
 xref: reactome:R-HSA-5227490 "NoRC:HDAC:DNMT methylates cytosine of the rRNA genes"
 never_in_taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe

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DNA-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 enables ISO (PMID:1606615)
(PMID:18754681)		 MGI
UniProt		 PMID:1606615 PMID:18754681 NCBI chrNW_004624828:2,316,042...2,358,866
Ensembl chrNW_004624828:2,315,251...2,358,711 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624842:6,450,972...6,505,929
Ensembl chrNW_004624842:6,450,852...6,475,785 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 enables ISO
IEA		 RGD
TreeGrafter
RHEA
InterPro
UniProt		 PMID:12473678 GO_REF:0000002 GO_REF:0000104 GO_REF:0000116 GO_REF:0000118 RGD:1359078 NCBI chrNW_004624828:2,316,042...2,358,866
Ensembl chrNW_004624828:2,315,251...2,358,711 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624738:7,481,084...7,581,332
Ensembl chrNW_004624738:7,485,842...7,581,056 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta enables ISO (PMID:17938196)
(PMID:16543361), (PMID:22133874), (PMID:27841881), (PMID:9662389)		 MGI PMID:9662389 PMID:16543361 PMID:17938196 PMID:22133874 PMID:27841881 NCBI chrNW_004624842:6,450,972...6,505,929
Ensembl chrNW_004624842:6,450,852...6,475,785 		JBrowse link
G Dnmt3l DNA methyltransferase 3 like NOT|enables ISO (PMID:11934864) MGI PMID:11934864 NCBI chrNW_004624745:29,869,174...29,878,189
Ensembl chrNW_004624745:29,869,196...29,878,169 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt3b DNA methyltransferase 3 beta enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624842:6,450,972...6,505,929
Ensembl chrNW_004624842:6,450,852...6,475,785 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 enables IEA UniProt GO_REF:0000003 NCBI chrNW_004624828:2,316,042...2,358,866
Ensembl chrNW_004624828:2,315,251...2,358,711 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha enables IEA UniProt GO_REF:0000003 NCBI chrNW_004624738:7,481,084...7,581,332
Ensembl chrNW_004624738:7,485,842...7,581,056 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta enables IEA UniProt GO_REF:0000003 NCBI chrNW_004624842:6,450,972...6,505,929
Ensembl chrNW_004624842:6,450,852...6,475,785 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 enables IEA UniProt GO_REF:0000003 NCBI chrNW_004624828:2,316,042...2,358,866
Ensembl chrNW_004624828:2,315,251...2,358,711 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha enables IEA UniProt GO_REF:0000003 NCBI chrNW_004624738:7,481,084...7,581,332
Ensembl chrNW_004624738:7,485,842...7,581,056 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta enables IEA UniProt GO_REF:0000003 NCBI chrNW_004624842:6,450,972...6,505,929
Ensembl chrNW_004624842:6,450,852...6,475,785 		JBrowse link
site-specific DNA-methyltransferase (adenine-specific) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC110347613 modification methylase CcrMI-like enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004625101:16,922...17,641 JBrowse link
G Mettl4 methyltransferase 4, N6-adenosine enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624770:12,905,138...12,937,859
Ensembl chrNW_004624770:12,905,100...12,938,189 		JBrowse link
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 NOT|enables ISO (PMID:30392959), (PMID:31632689), (PMID:31636962)
(PMID:30017583)		 UniProt PMID:30017583 PMID:30392959 PMID:31632689 PMID:31636962 NCBI chrNW_004624745:16,908,683...16,922,941
Ensembl chrNW_004624745:16,908,686...16,920,351 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18442
    catalytic activity 5599
      catalytic activity, acting on a nucleic acid 625
        catalytic activity, acting on DNA 253
          DNA-methyltransferase activity 7
            DNA (cytosine-5-)-methyltransferase activity + 4
            site-specific DNA-methyltransferase (adenine-specific) activity 3
            site-specific DNA-methyltransferase (cytosine-N4-specific) activity 0
Path 2
Term Annotations click to browse term
  molecular_function 18442
    catalytic activity 5599
      transferase activity 2397
        transferase activity, transferring one-carbon groups 235
          methyltransferase activity 227
            DNA-methyltransferase activity 7
              DNA (cytosine-5-)-methyltransferase activity + 4
              site-specific DNA-methyltransferase (adenine-specific) activity 3
              site-specific DNA-methyltransferase (cytosine-N4-specific) activity 0
paths to the root