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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA-methyltransferase activity
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Accession:GO:0009008 term browser browse the term
Definition:Catalysis of the transfer of a methyl group to a DNA molecule.
Synonyms:exact_synonym: DNA transmethylase activity;   deoxyribonucleate methylase activity;   deoxyribonucleate methyltransferase activity;   deoxyribonucleic acid methylase activity;   deoxyribonucleic acid methyltransferase activity
 broad_synonym: DNA methylase
 related_synonym: Type II DNA methylase;   deoxyribonucleic acid modification methylase activity
 xref: reactome:R-HSA-5227490 "NoRC:HDAC:DNMT methylates cytosine of the rRNA genes"
 never_in_taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe


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DNA-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 enables IDA
IEA		 (PMID:18754681) UniProt
Ensembl		 PMID:18754681 GO_REF:0000107 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta enables NAS
IEA		 (PMID:10325416), (PMID:10555141), (PMID:11102980) UniProt
InterPro		 PMID:10325416 PMID:10555141 PMID:11102980 GO_REF:0000002 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase enables TAS (PMID:2405387) PINC PMID:2405387 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 enables ISO
IBA
IEA
TAS
IDA		 (PMID:8940105)
(PMID:21745816)		 RGD
GO_Central
InterPro
PINC
UniProt
Ensembl
RHEA		 PMID:8940105 PMID:12473678 PMID:21745816 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 RGD:1359078 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha enables IDA
IBA
IEA		 (PMID:12138111), (PMID:19786833) ARUK-UCL
GO_Central
RHEA
Ensembl		 PMID:12138111 PMID:19786833 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta enables IEA
TAS
IDA
NAS		 (PMID:10433969)
(PMID:16543361)
(PMID:10647011)		 RHEA
UniProt
MGI		 PMID:10433969 PMID:10647011 PMID:16543361 GO_REF:0000116 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G DNMT3L DNA methyltransferase 3 like NOT|enables ISO (PMID:11934864) MGI PMID:11934864 NCBI chr21:44,246,339...44,261,897
Ensembl chr21:44,246,339...44,262,216 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3B DNA methyltransferase 3 beta enables IBA GO_Central GO_REF:0000033 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 enables IEA UniProt GO_REF:0000003 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha enables IEA UniProt GO_REF:0000003 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta enables IEA UniProt GO_REF:0000003 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 enables IEA UniProt GO_REF:0000003 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha enables IEA UniProt GO_REF:0000003 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta enables IEA UniProt GO_REF:0000003 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
site-specific DNA-methyltransferase (adenine-specific) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL4 methyltransferase 4, N6-adenosine enables IEA
IBA
IDA		 (PMID:32183942) RHEA
GO_Central
UniProt		 PMID:32183942 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr18:2,537,530...2,571,505
Ensembl chr18:2,537,525...2,571,509 		JBrowse link
G N6AMT1 N-6 adenine-specific DNA methyltransferase 1 enables
NOT|enables		 IDA (PMID:30017583)
(PMID:30392959), (PMID:31632689), (PMID:31636962)		 UniProt PMID:30017583 PMID:30392959 PMID:31632689 PMID:31636962 NCBI chr21:28,575,598...28,885,367
Ensembl chr21:28,872,191...28,885,371 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19683
    catalytic activity 6023
      catalytic activity, acting on a nucleic acid 655
        catalytic activity, acting on DNA 266
          DNA-methyltransferase activity 7
            DNA (cytosine-5-)-methyltransferase activity + 4
            site-specific DNA-methyltransferase (adenine-specific) activity 2
            site-specific DNA-methyltransferase (cytosine-N4-specific) activity 0
Path 2
Term Annotations click to browse term
  molecular_function 19683
    catalytic activity 6023
      transferase activity 2450
        transferase activity, transferring one-carbon groups 234
          methyltransferase activity 225
            DNA-methyltransferase activity 7
              DNA (cytosine-5-)-methyltransferase activity + 4
              site-specific DNA-methyltransferase (adenine-specific) activity 2
              site-specific DNA-methyltransferase (cytosine-N4-specific) activity 0
paths to the root