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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA-methyltransferase activity
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Accession:GO:0009008 term browser browse the term
Definition:Catalysis of the transfer of a methyl group to a DNA molecule.
Synonyms:exact_synonym: DNA transmethylase activity;   deoxyribonucleate methylase activity;   deoxyribonucleate methyltransferase activity;   deoxyribonucleic acid methylase activity;   deoxyribonucleic acid methyltransferase activity
 broad_synonym: DNA methylase
 related_synonym: Type II DNA methylase;   deoxyribonucleic acid modification methylase activity
 xref: reactome:R-HSA-5227490 "NoRC:HDAC:DNMT methylates cytosine of the rRNA genes"
 never_in_taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe


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DNA-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta enables IEA InterPro GO_REF:0000002 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 enables ISO
IBA
IEA		 RGD
GO_Central
Ensembl
InterPro
UniProt		 PMID:12473678 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 RGD:1359078 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta enables IEA Ensembl GO_REF:0000107 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900 		JBrowse link
G DNMT3L DNA methyltransferase 3 like NOT|enables ISO (PMID:11934864) MGI PMID:11934864 NCBI chr31:38,099,100...38,111,432 JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3B DNA methyltransferase 3 beta enables IBA GO_Central GO_REF:0000033 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900 		JBrowse link
site-specific DNA-methyltransferase (adenine-specific) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL4 methyltransferase 4, N6-adenosine enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:69,229,717...69,268,223
Ensembl chr 7:69,191,223...69,267,683 		JBrowse link
G N6AMT1 N-6 adenine-specific DNA methyltransferase 1 NOT|enables ISO (PMID:30392959), (PMID:31632689), (PMID:31636962)
(PMID:30017583)		 UniProt PMID:30017583 PMID:30392959 PMID:31632689 PMID:31636962 NCBI chr31:23,895,558...23,934,183
Ensembl chr31:23,895,584...23,909,940 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21949
    catalytic activity 5722
      catalytic activity, acting on a nucleic acid 614
        catalytic activity, acting on DNA 240
          DNA-methyltransferase activity 6
            DNA (cytosine-5-)-methyltransferase activity + 4
            site-specific DNA-methyltransferase (adenine-specific) activity 2
            site-specific DNA-methyltransferase (cytosine-N4-specific) activity 0
Path 2
Term Annotations click to browse term
  molecular_function 21949
    catalytic activity 5722
      transferase activity 2314
        transferase activity, transferring one-carbon groups 216
          methyltransferase activity 201
            DNA-methyltransferase activity 6
              DNA (cytosine-5-)-methyltransferase activity + 4
              site-specific DNA-methyltransferase (adenine-specific) activity 2
              site-specific DNA-methyltransferase (cytosine-N4-specific) activity 0
paths to the root