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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA-methyltransferase activity
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Accession:GO:0009008 term browser browse the term
Definition:Catalysis of the transfer of a methyl group to a DNA molecule.
Synonyms:exact_synonym: DNA transmethylase activity;   deoxyribonucleate methylase activity;   deoxyribonucleate methyltransferase activity;   deoxyribonucleic acid methylase activity;   deoxyribonucleic acid methyltransferase activity
 broad_synonym: DNA methylase
 related_synonym: Type II DNA methylase;   deoxyribonucleic acid modification methylase activity
 xref: reactome:R-HSA-5227490 "NoRC:HDAC:DNMT methylates cytosine of the rRNA genes"
 never_in_taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe


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DNA-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta enables IEA InterPro GO_REF:0000002 NCBI chr20:29,049,993...29,096,957
Ensembl chr20:30,186,069...30,215,487 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 enables ISO
IEA		 RGD
TreeGrafter
UniProt
Ensembl
InterPro
RHEA		 PMID:12473678 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 RGD:1359078 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2A:25,229,593...25,344,733
Ensembl chr2A:25,331,095...25,412,605 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta enables IEA Ensembl GO_REF:0000107 NCBI chr20:29,049,993...29,096,957
Ensembl chr20:30,186,069...30,215,487 		JBrowse link
G DNMT3L DNA methyltransferase 3 like NOT|enables ISO (PMID:11934864) MGI PMID:11934864 NCBI chr21:30,503,194...30,520,237
Ensembl chr21:43,798,778...43,814,283 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3B DNA methyltransferase 3 beta enables IEA TreeGrafter GO_REF:0000118 NCBI chr20:29,049,993...29,096,957
Ensembl chr20:30,186,069...30,215,487 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 enables IEA UniProt GO_REF:0000003 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha enables IEA UniProt GO_REF:0000003 NCBI chr2A:25,229,593...25,344,733
Ensembl chr2A:25,331,095...25,412,605 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta enables IEA UniProt GO_REF:0000003 NCBI chr20:29,049,993...29,096,957
Ensembl chr20:30,186,069...30,215,487 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 enables IEA UniProt GO_REF:0000003 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha enables IEA UniProt GO_REF:0000003 NCBI chr2A:25,229,593...25,344,733
Ensembl chr2A:25,331,095...25,412,605 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta enables IEA UniProt GO_REF:0000003 NCBI chr20:29,049,993...29,096,957
Ensembl chr20:30,186,069...30,215,487 		JBrowse link
site-specific DNA-methyltransferase (adenine-specific) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL4 methyltransferase 4, N6-adenosine enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:11,711,502...11,745,222
Ensembl chr18:14,018,279...14,051,974 		JBrowse link
G N6AMT1 N-6 adenine-specific DNA methyltransferase 1 NOT|enables ISO
IEA		 (PMID:30392959), (PMID:31632689), (PMID:31636962) UniProt
Ensembl		 PMID:30392959 PMID:31632689 PMID:31636962 GO_REF:0000107 NCBI chr21:15,303,430...15,316,596
Ensembl chr21:28,694,294...28,704,745 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19165
    catalytic activity 5365
      catalytic activity, acting on a nucleic acid 600
        catalytic activity, acting on DNA 243
          DNA-methyltransferase activity 6
            DNA (cytosine-5-)-methyltransferase activity + 4
            site-specific DNA-methyltransferase (adenine-specific) activity 2
            site-specific DNA-methyltransferase (cytosine-N4-specific) activity 0
Path 2
Term Annotations click to browse term
  molecular_function 19165
    catalytic activity 5365
      transferase activity 2154
        transferase activity, transferring one-carbon groups 205
          methyltransferase activity 193
            DNA-methyltransferase activity 6
              DNA (cytosine-5-)-methyltransferase activity + 4
              site-specific DNA-methyltransferase (adenine-specific) activity 2
              site-specific DNA-methyltransferase (cytosine-N4-specific) activity 0
paths to the root