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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular amino acid biosynthetic process
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Accession:GO:0008652 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
Synonyms:exact_synonym: amino acid biosynthetic process;   cellular amino acid anabolism;   cellular amino acid biosynthesis;   cellular amino acid formation;   cellular amino acid synthesis
 xref: Wikipedia:Amino_acid_synthesis


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arginine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asl argininosuccinate lyase JBrowse link 12 30,160,922 30,178,348 RGD:632221
G Ass1 argininosuccinate synthase 1 JBrowse link 3 10,327,411 10,375,847 RGD:631755
RGD:13792537
RGD:1624291
RGD:12859071
RGD:1600115
G Nags N-acetylglutamate synthase JBrowse link 10 90,084,607 90,089,693 RGD:13792537
arginine biosynthetic process via ornithine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asl argininosuccinate lyase JBrowse link 12 30,160,922 30,178,348 RGD:1600115
RGD:13792537
G Otc ornithine carbamoyltransferase JBrowse link X 13,524,804 13,601,074 RGD:13792537
asparagine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asns asparagine synthetase (glutamine-hydrolyzing) JBrowse link 4 33,742,876 33,761,106 RGD:2316002
RGD:13792537
RGD:1624291
G Asnsd1 asparagine synthetase domain containing 1 JBrowse link 9 52,988,042 53,009,054 RGD:1600115
aspartate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:1624291
RGD:13792537
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 JBrowse link 16 69,022,756 69,035,507 RGD:13792537
G Got2 glutamic-oxaloacetic transaminase 2 JBrowse link 19 9,587,637 9,613,323 RGD:1624291
RGD:1600115
beta-alanine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dpyd dihydropyrimidine dehydrogenase JBrowse link 2 221,823,692 222,694,627 RGD:1600115
G Upb1 beta-ureidopropionase 1 JBrowse link 20 14,167,383 14,193,724 RGD:634224
beta-alanine biosynthetic process via 3-ureidopropionate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Upb1 beta-ureidopropionase 1 JBrowse link 20 14,167,383 14,193,724 RGD:13792537
RGD:1600115
RGD:1624291
branched-chain amino acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcat1 branched chain amino acid transaminase 1 JBrowse link 4 179,259,305 179,340,021 RGD:1600115
G Bcat2 branched chain amino acid transaminase 2 JBrowse link 1 101,553,900 101,572,103 RGD:1600115
citrulline biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 JBrowse link 1 259,641,673 259,674,521 RGD:1624291
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase JBrowse link 6 26,657,507 26,680,459 RGD:10755426
RGD:13792537
G Otc ornithine carbamoyltransferase JBrowse link X 13,524,804 13,601,074 RGD:4144071
RGD:13792537
RGD:1624291
cysteine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbs cystathionine beta synthase JBrowse link 20 10,361,987 10,386,663 RGD:1624291
G Cth cystathionine gamma-lyase JBrowse link 2 264,266,959 264,293,040 RGD:1359024
RGD:1600115
RGD:1624291
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:1624291
cysteine biosynthetic process from serine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbs cystathionine beta synthase JBrowse link 20 10,361,987 10,386,663 RGD:1359024
RGD:13792537
cysteine biosynthetic process via cystathionine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbs cystathionine beta synthase JBrowse link 20 10,361,987 10,386,663 RGD:1600115
G Cth cystathionine gamma-lyase JBrowse link 2 264,266,959 264,293,040 RGD:1624291
RGD:13792537
D-serine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Srr serine racemase JBrowse link 10 61,756,138 61,772,327 RGD:1624291
RGD:13792537
gamma-aminobutyric acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abat 4-aminobutyrate aminotransferase JBrowse link 10 7,093,406 7,200,439 RGD:9588538
G Gad1 glutamate decarboxylase 1 JBrowse link 3 56,861,440 56,902,139 RGD:6480258
G Slc1a3 solute carrier family 1 member 3 JBrowse link 2 57,860,881 57,935,363 RGD:1624291
RGD:1600115
glutamate biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gls glutaminase JBrowse link 9 54,212,622 54,284,879 RGD:1600115
RGD:13792537
RGD:1624291
G Gls2 glutaminase 2 JBrowse link 7 2,605,679 2,621,853 RGD:13792537
G Glud1 glutamate dehydrogenase 1 JBrowse link 16 10,661,486 10,695,557 RGD:1624291
G Slc1a3 solute carrier family 1 member 3 JBrowse link 2 57,860,881 57,935,363 RGD:1624291
G Slc25a12 solute carrier family 25 member 12 JBrowse link 3 57,881,951 57,998,214 RGD:13628741
glutamine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Glul glutamate-ammonia ligase JBrowse link 13 71,331,052 71,340,207 RGD:2301548
RGD:2301547
G Lgsn lengsin, lens protein with glutamine synthetase domain JBrowse link 9 37,458,603 37,490,117 RGD:13792537
glycine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC688286 similar to threonine aldolase 1 JBrowse link 10 106,877,585 106,883,706 RGD:13792537
G Sardh sarcosine dehydrogenase JBrowse link 3 5,737,203 5,802,153 RGD:634034
G Shmt1 serine hydroxymethyltransferase 1 JBrowse link 10 47,030,813 47,059,216 RGD:2300383
G Shmt2 serine hydroxymethyltransferase 2 JBrowse link 7 70,824,718 70,829,822 RGD:2300383
glycine biosynthetic process from serine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shmt1 serine hydroxymethyltransferase 1 JBrowse link 10 47,030,813 47,059,216 RGD:2300383
RGD:13792537
G Shmt2 serine hydroxymethyltransferase 2 JBrowse link 7 70,824,718 70,829,822 RGD:2300383
RGD:13792537
glycine biosynthetic process, by transamination of glyoxylate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase JBrowse link 9 100,281,339 100,291,292 RGD:1599457
RGD:13792537
RGD:1624291
G Agxt2 alanine-glyoxylate aminotransferase 2 JBrowse link 2 60,337,667 60,379,144 RGD:1624291
RGD:1600115
histidine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 JBrowse link 6 99,282,850 99,350,367 RGD:1600115
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like JBrowse link 14 18,640,274 18,721,298 RGD:1600115
hydroxylysine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 JBrowse link 5 164,720,629 164,747,071 RGD:1600115
RGD:13792537
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 JBrowse link 8 99,977,334 100,059,736 RGD:1600115
RGD:13792537
RGD:1624291
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 JBrowse link 12 22,716,421 22,726,982 RGD:13792537
RGD:1624291
L-asparagine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asns asparagine synthetase (glutamine-hydrolyzing) JBrowse link 4 33,742,876 33,761,106 RGD:1600115
L-methionine salvage term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bhmt betaine-homocysteine S-methyltransferase JBrowse link 2 23,236,573 23,256,158 RGD:1624291
RGD:1600115
G Bhmt2 betaine-homocysteine S-methyltransferase 2 JBrowse link 2 23,272,320 23,289,266 RGD:1624291
RGD:1600115
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adi1 acireductone dioxygenase 1 JBrowse link 6 47,940,211 47,947,173 RGD:1600115
RGD:1624291
G Apip APAF1 interacting protein JBrowse link 3 92,969,128 92,998,104 RGD:1600115
RGD:13792537
RGD:1624291
G Enoph1 enolase-phosphatase 1 JBrowse link 14 11,172,359 11,198,799 RGD:1600115
RGD:13792537
RGD:1624291
G Mri1 methylthioribose-1-phosphate isomerase 1 JBrowse link 19 25,360,299 25,366,283 RGD:1600115
RGD:13792537
G Mtap methylthioadenosine phosphorylase JBrowse link 5 107,711,077 107,777,530 RGD:1600115
RGD:13792537
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apip APAF1 interacting protein JBrowse link 3 92,969,128 92,998,104 RGD:1600115
G Enoph1 enolase-phosphatase 1 JBrowse link 14 11,172,359 11,198,799 RGD:1600115
G Mri1 methylthioribose-1-phosphate isomerase 1 JBrowse link 19 25,360,299 25,366,283 RGD:1600115
L-proline biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 JBrowse link 1 259,641,673 259,674,521 RGD:1600115
G LOC108348083 delta-1-pyrroline-5-carboxylate synthase JBrowse link 1 259,057,407 259,089,727 RGD:1600115
G Noxred1 NADP-dependent oxidoreductase domain containing 1 JBrowse link 6 111,243,232 111,271,107 RGD:13792537
G Oat ornithine aminotransferase JBrowse link 1 204,562,289 204,582,070 RGD:1600115
G Pycr1 pyrroline-5-carboxylate reductase 1 JBrowse link 10 109,817,300 109,822,218 RGD:1600115
RGD:13792537
G Pycr2 pyrroline-5-carboxylate reductase 2 JBrowse link 13 99,184,624 99,188,418 RGD:1600115
RGD:13792537
G Pycr3 pyrroline-5-carboxylate reductase 3 JBrowse link 7 116,949,882 116,955,150 RGD:1600115
RGD:13792537
RGD:1624291
L-serine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Phgdh phosphoglycerate dehydrogenase JBrowse link 2 200,484,245 200,513,564 RGD:1600115
G Psat1 phosphoserine aminotransferase 1 JBrowse link 1 233,124,089 233,145,941 RGD:13792537
G Psph phosphoserine phosphatase JBrowse link 12 30,514,128 30,526,551 RGD:13792537
G Shmt2 serine hydroxymethyltransferase 2 JBrowse link 7 70,824,718 70,829,822 RGD:2300380
leucine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcat1 branched chain amino acid transaminase 1 JBrowse link 4 179,259,305 179,340,021 RGD:13792537
G Bcat2 branched chain amino acid transaminase 2 JBrowse link 1 101,553,900 101,572,103 RGD:1582175
RGD:13792537
lysine biosynthetic process via aminoadipic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase JBrowse link 8 1,432,757 1,450,175 RGD:13792537
G Aass aminoadipate-semialdehyde synthase JBrowse link 4 50,152,005 50,208,935 RGD:13792537
methionine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bhmt betaine-homocysteine S-methyltransferase JBrowse link 2 23,236,573 23,256,158 RGD:1359026
RGD:1624291
G Bhmt2 betaine-homocysteine S-methyltransferase 2 JBrowse link 2 23,272,320 23,289,266 RGD:1600115
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 JBrowse link 6 99,282,850 99,350,367 RGD:1624291
RGD:1600115
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like JBrowse link 14 18,640,274 18,721,298 RGD:1600115
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:1624291
RGD:13792537
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase JBrowse link 17 66,210,444 66,295,014 RGD:1359026
RGD:1600115
RGD:1624291
RGD:1601423
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase JBrowse link 1 37,743,089 37,774,485 RGD:1624291
RGD:13792537
negative regulation of citrulline biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 13 50,091,644 50,153,808 RGD:1624291
RGD:1600115
ornithine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 JBrowse link 1 259,641,673 259,674,521 RGD:1624291
positive regulation of L-dopa biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
proline biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 JBrowse link 1 259,641,673 259,674,521 RGD:1624291
G Pycr1 pyrroline-5-carboxylate reductase 1 JBrowse link 10 109,817,300 109,822,218 RGD:1624291
G Pycr2 pyrroline-5-carboxylate reductase 2 JBrowse link 13 99,184,624 99,188,418 RGD:1624291
RGD:1600115
selenocysteine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sephs1 selenophosphate synthetase 1 JBrowse link 17 77,312,562 77,340,934 RGD:13792537
G Sephs2 selenophosphate synthetase 2 JBrowse link 1 198,719,158 198,721,476 RGD:1624291
serine family amino acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 JBrowse link 6 99,282,850 99,350,367 RGD:1624291
G Phgdh phosphoglycerate dehydrogenase JBrowse link 2 200,484,245 200,513,564 RGD:61693
threonine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Thnsl2 threonine synthase-like 2 JBrowse link 4 98,976,559 98,997,187 RGD:1624291
RGD:13792537
tyrosine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pah phenylalanine hydroxylase JBrowse link 7 28,066,639 28,129,772 RGD:1601531
RGD:13792537
RGD:1601535
valine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcat1 branched chain amino acid transaminase 1 JBrowse link 4 179,259,305 179,340,021 RGD:13792537
G Bcat2 branched chain amino acid transaminase 2 JBrowse link 1 101,553,900 101,572,103 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18157
    metabolic process 10835
      primary metabolic process 9749
        cellular amino acid metabolic process 264
          cellular amino acid biosynthetic process 66
            L-beta-ethynylserine biosynthetic process 0
            L-propargylglycine biosynthetic process 0
            alpha-amino acid biosynthetic process + 62
            amino acid salvage + 7
            aromatic amino acid family biosynthetic process + 4
            beta-alanine biosynthetic process + 2
            branched-chain amino acid biosynthetic process + 2
            diaminopimelate biosynthetic process 0
            fructoselysine biosynthetic process 0
            gamma-aminobutyric acid biosynthetic process 3
            negative regulation of cellular amino acid biosynthetic process + 1
            positive regulation of cellular amino acid biosynthetic process + 1
            regulation of cellular amino acid biosynthetic process + 2
            sulfur amino acid biosynthetic process + 15
Path 2
Term Annotations click to browse term
  biological_process 18157
    metabolic process 10835
      small molecule metabolic process 1715
        organic acid metabolic process 986
          oxoacid metabolic process 961
            carboxylic acid metabolic process 916
              cellular amino acid metabolic process 264
                cellular amino acid biosynthetic process 66
                  L-beta-ethynylserine biosynthetic process 0
                  L-propargylglycine biosynthetic process 0
                  alpha-amino acid biosynthetic process + 62
                  amino acid salvage + 7
                  aromatic amino acid family biosynthetic process + 4
                  beta-alanine biosynthetic process + 2
                  branched-chain amino acid biosynthetic process + 2
                  diaminopimelate biosynthetic process 0
                  fructoselysine biosynthetic process 0
                  gamma-aminobutyric acid biosynthetic process 3
                  negative regulation of cellular amino acid biosynthetic process + 1
                  positive regulation of cellular amino acid biosynthetic process + 1
                  regulation of cellular amino acid biosynthetic process + 2
                  sulfur amino acid biosynthetic process + 15
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.