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ONTOLOGY REPORT - ANNOTATIONS

Term:ubiquitin-like modifier activating enzyme activity
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Accession:GO:0008641 term browser browse the term
Definition:Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.
Synonyms:narrow_synonym: small protein activating enzyme activity
 alt_id: GO:0008642

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Atg12 activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 enables ISO (PMID:22170151)
(PMID:20723759)
(PMID:37943659)
(PMID:11890701) 		UniProt
MGI		 PMID:11890701 PMID:20723759 PMID:22170151 PMID:37943659 NCBI chrNW_004955429:14,076,976...14,301,034
Ensembl chrNW_004955429:14,076,960...14,304,236 		JBrowse link
Atg8 activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 enables ISO (PMID:11890701) MGI PMID:11890701 NCBI chrNW_004955429:14,076,976...14,301,034
Ensembl chrNW_004955429:14,076,960...14,304,236 		JBrowse link
FAT10 activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Uba6 ubiquitin like modifier activating enzyme 6 enables ISO (PMID:17889673) UniProt PMID:17889673 NCBI chrNW_004955447:5,213,792...5,282,266
Ensembl chrNW_004955447:5,213,146...5,284,553 		JBrowse link
ISG15 activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Uba7 ubiquitin like modifier activating enzyme 7 enables ISO (PMID:16428300)
(PMID:15485925), (PMID:16139798) 		HGNC-UCL
MGI		 PMID:15485925 PMID:16139798 PMID:16428300 NCBI chrNW_004955532:1,697,667...1,706,668
Ensembl chrNW_004955532:1,695,956...1,706,676 		JBrowse link
NEDD8 activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nae1 NEDD8 activating enzyme E1 subunit 1 contributes_to ISO (PMID:12740388) UniProtKB PMID:12740388 NCBI chrNW_004955433:23,333,797...23,358,255
Ensembl chrNW_004955433:23,333,742...23,358,579 		JBrowse link
G Uba3 ubiquitin like modifier activating enzyme 3 contributes_to
enables 		ISO (PMID:12740388)
(PMID:19245792)
(PMID:10207026) 		UniProt
MGI
RGD		 PMID:10207026 PMID:11818503 PMID:12740388 PMID:19245792 RGD:634396 NCBI chrNW_004955421:18,781,015...18,801,266
Ensembl chrNW_004955421:18,780,730...18,801,266 		JBrowse link
SUMO activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sae1 SUMO1 activating enzyme subunit 1 contributes_to ISO (PMID:10187858), (PMID:20164921)
(PMID:15094046) 		UniProt
MGI		 PMID:10187858 PMID:15094046 PMID:20164921 NCBI chrNW_004955574:1,090,446...1,158,266
Ensembl chrNW_004955574:1,090,446...1,161,972 		JBrowse link
G Uba2 ubiquitin like modifier activating enzyme 2 contributes_to
enables 		ISO (PMID:10187858)
(PMID:15094046)
(PMID:21554500)
(PMID:20164921) 		UniProt
MGI		 PMID:10187858 PMID:15094046 PMID:20164921 PMID:21554500 NCBI chrNW_004955468:4,034,776...4,072,766
Ensembl chrNW_004955468:4,034,854...4,072,106 		JBrowse link
ubiquitin activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Uba1 ubiquitin like modifier activating enzyme 1 enables ISO (PMID:12629039), (PMID:21685362)
(PMID:1511901)
(PMID:33108101) 		MGI
UniProt		 PMID:1511901 PMID:12629039 PMID:21685362 PMID:33108101 NCBI chrNW_004955516:876,542...898,763
Ensembl chrNW_004955516:876,354...891,206 		JBrowse link
G Uba6 ubiquitin like modifier activating enzyme 6 enables ISO (PMID:23499007) MGI PMID:23499007 NCBI chrNW_004955447:5,213,792...5,282,266
Ensembl chrNW_004955447:5,213,146...5,284,553 		JBrowse link
UFM1 activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Uba5 ubiquitin like modifier activating enzyme 5 enables ISO (PMID:27545681)
(PMID:15071506), (PMID:27653677), (PMID:29295865), (PMID:30412706), (PMID:34588452)
(PMID:20018847), (PMID:33372156)
(PMID:21304510) 		UniProt
MGI		 PMID:15071506 PMID:20018847 PMID:21304510 PMID:27545681 PMID:27653677 More... NCBI chrNW_004955501:5,841,516...5,864,304
Ensembl chrNW_004955501:5,841,606...5,870,953 		JBrowse link
URM1 activating enzyme activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mocs3 molybdenum cofactor synthesis 3 enables ISO (PMID:19017811) UniProt PMID:19017811 NCBI chrNW_004955445:7,470,030...7,472,323
Ensembl chrNW_004955445:7,470,888...7,472,267 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 14440
    ATP-dependent activity 335
      ubiquitin-like modifier activating enzyme activity 10
        Atg12 activating enzyme activity 1
        Atg8 activating enzyme activity 1
        FAT10 activating enzyme activity 1
        Hub1 activating enzyme activity 0
        ISG15 activating enzyme activity 1
        NEDD8 activating enzyme activity 2
        SUMO activating enzyme activity 2
        UFM1 activating enzyme activity 1
        URM1 activating enzyme activity 1
        ubiquitin activating enzyme activity 2
Path 2
Term Annotations click to browse term
  molecular_function 14440
    catalytic activity 3888
      ligase activity 141
        ligase activity, forming carbon-sulfur bonds 36
          ubiquitin-like modifier activating enzyme activity 10
            Atg12 activating enzyme activity 1
            Atg8 activating enzyme activity 1
            FAT10 activating enzyme activity 1
            Hub1 activating enzyme activity 0
            ISG15 activating enzyme activity 1
            NEDD8 activating enzyme activity 2
            SUMO activating enzyme activity 2
            UFM1 activating enzyme activity 1
            URM1 activating enzyme activity 1
            ubiquitin activating enzyme activity 2
paths to the root