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ONTOLOGY REPORT - ANNOTATIONS


Term:apoptotic mitochondrial changes
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Accession:GO:0008637 term browser browse the term
Definition:The morphological and physiological alterations undergone by mitochondria during apoptosis.
Comment:This term was created to reflect the fundamental role of the mitochondrial compartment in apoptosis. Most processes under this node occur during the signaling phase of apoptosis, but e.g. GO:0043653 'mitochondrial fragmentation involved in apoptotic process' cannot be confidently placed under the signaling phase. For this reason, the parent term GO:0008637 'apoptotic mitochondrial changes' is not linked to the signaling or execution phase specifically, but its descendants are when current knowledge allows for it.



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apoptotic mitochondrial changes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm2 apoptosis inducing factor, mitochondria associated 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:11980907)
RGD PMID:11980907 PMID:21873635 RGD:13792537 NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236
JBrowse link
G Akt1 AKT serine/threonine kinase 1 acts_upstream_of_or_within ISO (MGI:2669068|PMID:12869584) RGD PMID:12869584 MGI:2669068 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IEP RGD PMID:30131474 RGD:15036798 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISO (PMID:19061639) RGD PMID:19061639 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:9843949)
(MGI:2677915|PMID:12925707)
GO_REF:0000024
RGD
UniProt
PMID:9843949 PMID:12925707 GO_REF:0000024 MGI:2677915 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO (MGI:2686748|PMID:14707049) RGD PMID:14707049 MGI:2686748 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bid BH3 interacting domain death agonist involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1277505|PMID:9727492)
RGD PMID:9727492 PMID:21873635 MGI:1277505, RGD:13792537 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bik BCL2-interacting killer involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1202139|PMID:9525867)
RGD PMID:9525867 PMID:21873635 MGI:1202139, RGD:13792537 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (MGI:2686748|PMID:14707049) RGD PMID:14707049 MGI:2686748 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:12082630) RGD PMID:12082630 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Dap3 death associated protein 3 acts_upstream_of_or_within ISO (MGI:1926997|PMID:11017876) RGD PMID:11017876 MGI:1926997 NCBI chr 2:174,319,341...174,347,489
Ensembl chr 2:174,318,983...174,346,461
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within ISO MGI:104990 (MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:3047441 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Hk2 hexokinase 2 acts_upstream_of_or_within ISO MGI:1353495|MGI:2145814 (MGI:3777889|PMID:18350175)
(PMID:18350175)
RGD PMID:18350175 MGI:3777889 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:21854881 PMID:21873635 RGD:10402841, RGD:13792537 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Jtb jumping translocation breakpoint acts_upstream_of_or_within ISO (MGI:5009395|PMID:17369841) RGD PMID:17369841 MGI:5009395 NCBI chr 2:175,685,392...175,689,609
Ensembl chr 2:175,684,993...175,690,108
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 acts_upstream_of_or_within ISO (MGI:3577836|PMID:15882989) RGD PMID:15882989 MGI:3577836 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member acts_upstream_of_or_within ISO (MGI:4421270|PMID:19919825) RGD PMID:19919825 MGI:4421270 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 involved_in ISO
ISS
(PMID:15186778)
GO_REF:0000024
RGD
UniProt
PMID:15186778 GO_REF:0000024 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
JBrowse link
G Pim2 Pim-2 proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (MGI:2669068|PMID:12869584) RGD PMID:12869584 MGI:2669068 NCBI chr  X:14,617,582...14,622,851
Ensembl chr  X:14,617,582...14,622,851
JBrowse link
G Ppif peptidylprolyl isomerase F acts_upstream_of_or_within ISO MGI:1315197|MGI:1353495 (MGI:3777889|PMID:18350175) RGD PMID:18350175 MGI:3777889 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta acts_upstream_of_or_within ISO (MGI:3694309|PMID:16717086) RGD PMID:16717086 MGI:3694309 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
JBrowse link
G Rnf7 ring finger protein 7 acts_upstream_of_or_within ISO (MGI:1333612|PMID:10082581) RGD PMID:10082581 MGI:1333612 NCBI chr 8:97,038,845...97,048,080
Ensembl chr 8:97,038,840...97,047,824
JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1315197|MGI:2145814 (MGI:3777889|PMID:18350175)
Ensembl
RGD
PMID:18350175 GO_REF:0000107 MGI:3777889 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO MGI:1857344 (MGI:1931647|PMID:11226230) RGD PMID:11226230 MGI:1931647 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
mitochondrial fragmentation involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg3 autophagy related 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:4835103|PMID:20723759)
UniProt
RGD
PMID:20723759 GO_REF:0000024 MGI:4835103 NCBI chr11:55,624,928...55,653,212
Ensembl chr11:55,624,917...55,653,224
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in ISO
ISS
(PMID:12499352)
GO_REF:0000024
RGD
UniProt
PMID:12499352 GO_REF:0000024 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO (PMID:20436456) RGD PMID:20436456 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:15824730) RGD PMID:15824730 NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636
JBrowse link
G Dnm1l dynamin 1-like involved_in IMP
IBA
ISO
PMID:21873635
(PMID:12499352), (PMID:18353969), (PMID:21149567)
RGD PMID:12499352 PMID:18353969 PMID:21149567 PMID:17443673 PMID:21873635 RGD:12738363, RGD:13792537 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 involved_in ISO
ISS
(PMID:16778220)
GO_REF:0000024
RGD
UniProt
PMID:16778220 GO_REF:0000024 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Fis1 fission, mitochondrial 1 involved_in IMP
IBA
ISO
ISS
PMID:21873635
(PMID:16118244), (PMID:17545159), (PMID:18353969), (PMID:19864424)
GO_REF:0000024
RGD
UniProt
PMID:16118244 PMID:17545159 PMID:18353969 PMID:19864424 PMID:18940801 More... GO_REF:0000024, RGD:2314538, RGD:13792537 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Mff mitochondrial fission factor involved_in ISO
IEA
(PMID:18353969), (PMID:21149567)
GO_REF:0000107
RGD
Ensembl
PMID:18353969 PMID:21149567 GO_REF:0000107 NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039
JBrowse link
G Nptx1 neuronal pentraxin 1 IMP RGD PMID:22279230 RGD:6903322 NCBI chr10:104,811,107...104,820,358
Ensembl chr10:104,811,403...104,820,367
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta IMP RGD PMID:18940801 RGD:2314538 NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:28761318 RGD:13432138 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (PMID:26618722) RGD PMID:26618722 NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618
JBrowse link
mitochondrial outer membrane permeabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO MGI:1929260 (MGI:5566519|PMID:20436477) RGD PMID:20436477 MGI:5566519 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 involved_in ISO
ISS
(PMID:18188704) RGD PMID:18188704 PMID:18188704 RGD:8553738 NCBI chr 1:243,024,611...243,031,749
Ensembl chr 1:243,024,614...243,031,653
JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in IBA
ISO
PMID:21873635
(PMID:18371312)
RGD PMID:18371312 PMID:21873635 RGD:13792537 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bnip3l BCL2 interacting protein 3 like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 acts_upstream_of_or_within ISO (MGI:2158099|PMID:11700312) RGD PMID:11700312 MGI:2158099 NCBI chr 3:154,335,558...154,519,006
Ensembl chr 3:154,335,400...154,518,793
JBrowse link
G LOC102548901 protein Bop-like involved_in ISO (PMID:23055042) RGD PMID:23055042
G Rhot1 ras homolog family member T1 involved_in ISO (PMID:12482879) RGD PMID:12482879 NCBI chr10:65,198,700...65,262,807
Ensembl chr10:65,170,560...65,262,804
JBrowse link
G Rhot2 ras homolog family member T2 involved_in ISS
ISO
GO_REF:0000024
(PMID:12482879)
UniProt
RGD
PMID:12482879 GO_REF:0000024 NCBI chr10:14,858,954...14,864,751
Ensembl chr10:14,858,956...14,864,751
JBrowse link
G Vdac2 voltage-dependent anion channel 2 involved_in ISO
ISS
(PMID:31015432)
GO_REF:0000024
RGD
UniProt
PMID:31015432 GO_REF:0000024 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
JBrowse link
negative regulation of mitochondrial membrane permeability involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa2 acetyl-CoA acyltransferase 2 involved_in ISO
IEA
(PMID:18371312)
GO_REF:0000107
RGD
Ensembl
PMID:18371312 GO_REF:0000107 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Bnip3 BCL2 interacting protein 3 IMP RGD PMID:17980495 RGD:11561965 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Nol3 nucleolar protein 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:5573029|PMID:24312627)
Ensembl
RGD
PMID:24312627 GO_REF:0000107 MGI:5573029 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Slc25a4 solute carrier family 25 member 4 IDA RGD PMID:22564366 RGD:9681467 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa2 acetyl-CoA acyltransferase 2 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:18371312)
Ensembl
UniProt
RGD
PMID:18371312 GO_REF:0000024 GO_REF:0000107 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:15901672) RGD PMID:15901672 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:9393856)
(PMID:15901672), (PMID:9393856)
RGD PMID:9393856 PMID:15901672 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO (MGI:5796062|PMID:27098698) RGD PMID:27098698 MGI:5796062 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:104995 (MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:3047441 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:20625543) RGD PMID:20625543
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (MGI:4437986|PMID:19096392) RGD PMID:19096392 MGI:4437986 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Mpv17l MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:1,988,451...2,025,300
Ensembl chr10:1,988,136...2,007,649
JBrowse link
G Slc25a31 solute carrier family 25 member 31 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:123,695,387...123,711,275
Ensembl chr 2:123,695,408...123,710,795
JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:19154410)
UniProt
RGD
PMID:19154410 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967
JBrowse link
G Slc35f6 solute carrier family 35, member F6 involved_in ISS
ISO
GO_REF:0000024
(PMID:19154410)
UniProt
RGD
PMID:19154410 GO_REF:0000024 NCBI chr 6:25,725,822...25,737,720
Ensembl chr 6:25,725,819...25,737,730
JBrowse link
G Tmem14a transmembrane protein 14A involved_in ISO (PMID:21723035) RGD PMID:21723035 NCBI chr 9:23,640,594...23,652,379
Ensembl chr 9:23,733,039...23,734,463
Ensembl chr 9:23,733,039...23,734,463
JBrowse link
negative regulation of release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5294538|PMID:18977203)
UniProt
RGD
PMID:18977203 GO_REF:0000024 MGI:5294538 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Arrb2 arrestin, beta 2 IMP RGD PMID:19171933 RGD:5510006 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Avp arginine vasopressin involved_in ISO (PMID:18402937) RGD PMID:18402937 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:15901672) RGD PMID:15901672 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:9393856)
(PMID:15901672), (PMID:9393856)
RGD PMID:9393856 PMID:15901672 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l2 Bcl2-like 2 IDA RGD PMID:10724126 RGD:14394498 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Fxn frataxin involved_in IEA
ISO
GO_REF:0000107
(PMID:16608849)
Ensembl
RGD
PMID:16608849 GO_REF:0000107 NCBI chr 1:221,874,007...221,897,841
Ensembl chr 1:221,872,420...221,897,540
JBrowse link
G Ghitm growth hormone inducible transmembrane protein involved_in ISO (PMID:18417609) RGD PMID:18417609 NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879
JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in ISO
IEA
(PMID:12221075)
GO_REF:0000107
RGD
Ensembl
PMID:12221075 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Hgf hepatocyte growth factor involved_in ISO (PMID:20655899) RGD PMID:20655899 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A acts_upstream_of_or_within ISO (MGI:5306879|PMID:21856340) RGD PMID:21856340 MGI:5306879 NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5294538|PMID:18977203)
UniProt
RGD
PMID:18977203 GO_REF:0000024 MGI:5294538 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Lmna lamin A/C involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4879057|PMID:21151901)
Ensembl
RGD
PMID:21151901 GO_REF:0000107 MGI:4879057 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:18006463 RGD:12738362 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA
IEA
IBA
ISO
PMID:10590251
GO_REF:0000107
PMID:21873635
(PMID:15004034)
Ensembl
RGD
PMID:15004034 PMID:10590251 PMID:21873635 GO_REF:0000107, RGD:10047155, RGD:13792537 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
ISO
GO_REF:0000024
(MGI:3692706|PMID:16839884)
(PMID:21149567)
ParkinsonsUK-UCL
RGD
PMID:16839884 PMID:21149567 GO_REF:0000024 MGI:3692706 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Pam16 presequence translocase associated motor 16 IDA RGD PMID:24069394 RGD:13462066 NCBI chr10:10,942,534...10,950,654
Ensembl chr10:10,943,001...10,950,649
JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISS
ISO
GO_REF:0000024
(MGI:3692706|PMID:16839884)
ParkinsonsUK-UCL
RGD
PMID:16839884 GO_REF:0000024 MGI:3692706 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506
JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISS
ISO
GO_REF:0000024
(PMID:19228691)
UniProt
RGD
PMID:19228691 GO_REF:0000024 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Prelid1 PRELI domain containing 1 involved_in ISO (PMID:23931759) RGD PMID:23931759 NCBI chr17:9,305,349...9,308,389
Ensembl chr17:9,305,361...9,308,407
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
ISS
(PMID:19880420), (PMID:23453807)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:19880420 PMID:23453807 GO_REF:0000024 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISO
ISS
(PMID:19729910)
GO_REF:0000024
RGD
UniProt
PMID:19729910 GO_REF:0000024 NCBI chr  X:104,656,809...104,665,126
Ensembl chr  X:104,656,812...104,665,097
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO (PMID:23931759) RGD PMID:23931759 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042
JBrowse link
positive regulation of mitochondrial membrane permeability involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in ISO
ISS
(PMID:22304920)
GO_REF:0000024
RGD
UniProt
PMID:22304920 GO_REF:0000024 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO MGI:1197519 (MGI:3581932|PMID:15967824) RGD PMID:15967824 MGI:3581932 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2l11 Bcl2-like 11 acts_upstream_of_or_within ISO MGI:99702 (MGI:3581932|PMID:15967824) RGD PMID:15967824 MGI:3581932 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Mir29a microRNA 29a involved_in ISO (PMID:20041405) RGD PMID:20041405 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir29b1 microRNA 29b-1 involved_in ISO (PMID:20041405) RGD PMID:20041405 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067
JBrowse link
G Mir29b2 microRNA 29b-2 involved_in ISO (PMID:20041405) RGD PMID:20041405 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456
JBrowse link
G Stpg1 sperm-tail PG-rich repeat containing 1 involved_in IBA
ISO
PMID:21873635
(PMID:23028632)
RGD PMID:23028632 PMID:21873635 RGD:13792537 NCBI chr 5:147,717,084...147,769,792
Ensembl chr 5:147,726,646...147,769,788
JBrowse link
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 acts_upstream_of_or_within ISO (MGI:4437986|PMID:19096392) RGD PMID:19096392 MGI:4437986 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO
GO_REF:0000024
(MGI:5796067|PMID:26949185)
UniProt
RGD
PMID:26949185 GO_REF:0000024 MGI:5796067 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 involved_in ISO (PMID:26666268), (PMID:30092269) RGD PMID:26666268 PMID:30092269 NCBI chr20:12,725,839...12,727,638
Ensembl chr20:12,725,842...12,732,763
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISS
ISO
GO_REF:0000024
(MGI:5514334|PMID:16543145)
UniProt
RGD
PMID:16543145 GO_REF:0000024 MGI:5514334 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
ISO
GO_REF:0000024
(MGI:5514334|PMID:16543145)
UniProt
RGD
PMID:16543145 GO_REF:0000024 MGI:5514334 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO UniProtKB:Q9HD36 (PMID:19255499) RGD PMID:19255499 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor involved_in ISO (PMID:15034012) RGD PMID:15034012 NCBI chr 6:131,705,312...131,709,697
Ensembl chr 6:131,705,323...131,709,690
JBrowse link
G Zfp13 zinc finger protein 13 involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:12,615,470...12,623,615
Ensembl chr10:12,615,190...12,623,615
JBrowse link
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbc3 Bcl-2 binding component 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:17024184)
MGI:2681654 (MGI:3804133|PMID:16705087)
RGD PMID:16705087 PMID:17024184 PMID:21873635 MGI:3804133, RGD:13792537 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within ISO MGI:2678372 (MGI:2675761|PMID:12952892) RGD PMID:12952892 MGI:2675761 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 acts_upstream_of_or_within ISO (MGI:3607027|PMID:16227588) RGD PMID:16227588 MGI:3607027 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784
JBrowse link
positive regulation of release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in ISO (PMID:17289999) RGD PMID:17289999 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 IMP RGD PMID:12485416 RGD:2317097 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in ISO
ISS
(PMID:14963330), (PMID:21262771)
GO_REF:0000024
RGD
UniProt
PMID:14963330 PMID:21262771 GO_REF:0000024 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISO
IEA
IBA
UniProtKB:P70444 (PMID:21041309)
GO_REF:0000002
PMID:21873635
RGD
InterPro
PMID:21041309 PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2l11 Bcl2-like 11 involved_in ISO UniProtKB:P70444 (PMID:17289999), (PMID:21041309) RGD PMID:17289999 PMID:21041309 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bid BH3 interacting domain death agonist involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
UniProtKB:P70444 (PMID:17289999), (PMID:21041309), (PMID:21262771), (PMID:32029622)
UniProtKB:O08734|UniProtKB:P70444 (MGI:5009197|PMID:10950869), (MGI:5009775|PMID:21041309)
UniProt
RGD
PMID:10950869 PMID:17289999 PMID:21041309 PMID:21262771 PMID:32029622 More... GO_REF:0000024 MGI:5009197 MGI:5009775, RGD:13792537 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bik BCL2-interacting killer involved_in ISO (PMID:21041309) RGD PMID:21041309 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
JBrowse link
G Bmf Bcl2 modifying factor involved_in ISO UniProtKB:P70444 (MGI:5009775|PMID:21041309) RGD PMID:21041309 MGI:5009775 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO (PMID:20436456) RGD PMID:20436456 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Casp1 caspase 1 involved_in ISO (MGI:3029677|PMID:14663141) RGD PMID:14663141 MGI:3029677 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Cideb cell death-inducing DFFA-like effector b involved_in ISO (PMID:12595532) RGD PMID:12595532 NCBI chr15:29,252,203...29,256,759
Ensembl chr15:29,252,213...29,256,605
JBrowse link
G Dnm1l dynamin 1-like involved_in ISO (PMID:21149567) RGD PMID:21149567 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Fam162a family with sequence similarity 162, member A involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:5319617|PMID:15082785)
(PMID:15082785)
PMID:21873635
UniProt
RGD
PMID:15082785 PMID:21873635 GO_REF:0000024 MGI:5319617, RGD:13792537 NCBI chr11:64,680,937...64,711,239
Ensembl chr11:64,680,323...64,711,239
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Hrk harakiri, BCL2 interacting protein involved_in ISO (PMID:21041309) RGD PMID:21041309 NCBI chr12:38,387,484...38,409,652 JBrowse link
G LOC120095320 protein FAM162A-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:36,389,447...36,391,357
Ensembl chr10:36,390,113...36,390,613
JBrowse link
G Mff mitochondrial fission factor involved_in ISO
IEA
(PMID:21149567)
GO_REF:0000107
RGD
Ensembl
PMID:21149567 GO_REF:0000107 NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:18852119)
PMID:21873635
UniProt
RGD
PMID:18852119 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in ISO
IEA
(PMID:22984561)
GO_REF:0000107
RGD
Ensembl
PMID:22984561 GO_REF:0000107 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) RGD PMID:16199525 NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643
JBrowse link
G Pdcd5 programmed cell death 5 involved_in ISO (PMID:16374546) RGD PMID:16374546 NCBI chr 1:88,305,869...88,311,200
Ensembl chr 1:88,305,869...88,311,200
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:19880420) RGD PMID:19880420 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Pla2g6 phospholipase A2 group VI IDA RGD PMID:18936091 RGD:6482750 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO (PMID:22984561) RGD PMID:22984561 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14500711), (PMID:14699081), (PMID:15705586), (PMID:17289999) RGD PMID:14500711 PMID:14699081 PMID:15705586 PMID:17289999 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISS
ISO
GO_REF:0000024
(MGI:3575990|PMID:15800627)
UniProt
RGD
PMID:15800627 GO_REF:0000024 MGI:3575990 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:14730312) RGD PMID:14730312 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Tnfsf10 TNF superfamily member 10 involved_in ISO (PMID:22266862) RGD PMID:22266862 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:14963330) RGD PMID:14963330 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Wdr35 WD repeat domain 35 IMP RGD PMID:23289926 RGD:11553920 NCBI chr 6:31,771,315...31,831,450
Ensembl chr 6:31,771,360...31,831,029
JBrowse link
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO MGI:1857429 (MGI:2675761|PMID:12952892) RGD PMID:12952892 MGI:2675761 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 acts_upstream_of ISO MGI:2681654 (MGI:3804133|PMID:16705087) RGD PMID:16705087 MGI:3804133 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) RGD PMID:16199525 NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643
JBrowse link
regulation of mitochondrial membrane permeability involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO MGI:108093|MGI:1929260|MGI:98834 (MGI:3042308|PMID:14963330), (MGI:5521267|PMID:23744079) RGD PMID:14963330 PMID:23744079 MGI:3042308 MGI:5521267 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO MGI:1929260|MGI:99702 (MGI:3042308|PMID:14963330), (MGI:5521267|PMID:23744079) RGD PMID:14963330 PMID:23744079 MGI:3042308 MGI:5521267 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:5444772|PMID:23051746)
ParkinsonsUK-UCL
RGD
PMID:23051746 GO_REF:0000024 MGI:5444772 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:108093|MGI:99702 (MGI:5521267|PMID:23744079), (MGI:5566519|PMID:20436477) RGD PMID:20436477 PMID:23744079 MGI:5521267 MGI:5566519 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189
JBrowse link
G Naif1 nuclear apoptosis inducing factor 1 involved_in ISO (PMID:16378748) RGD PMID:16378748 NCBI chr 3:15,742,337...15,747,672
Ensembl chr 3:15,742,919...15,747,669
JBrowse link
G Them4 thioesterase superfamily member 4 involved_in ISO
ISS
(PMID:19168129)
GO_REF:0000024
RGD
UniProt
PMID:19168129 GO_REF:0000024 NCBI chr 2:181,953,550...181,974,708
Ensembl chr 2:181,953,550...181,974,708
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:99702 (MGI:3042308|PMID:14963330) RGD PMID:14963330 MGI:3042308 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:18591963) RGD PMID:18591963 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863
JBrowse link
G Tmem102 transmembrane protein 102 involved_in ISO (PMID:17828305) RGD PMID:17828305 NCBI chr10:54,523,901...54,525,999
Ensembl chr10:54,523,585...54,525,990
JBrowse link
regulation of release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plscr3 phospholipid scramblase 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:14573790), (PMID:18358005)
UniProt
RGD
PMID:14573790 PMID:18358005 GO_REF:0000024 NCBI chr10:54,566,556...54,573,240
Ensembl chr10:54,566,873...54,578,709
JBrowse link
release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098 (MGI:3760368|PMID:11311799) RGD PMID:11311799 MGI:3760368 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Bad BCL2-associated agonist of cell death involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3029528 (MGI:3029504|PMID:12431371)
RGD PMID:12431371 PMID:21873635 MGI:3029504, RGD:13792537 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in IMP
ISO
positive regulation
(MGI:5009197|PMID:10950869)
UniProtKB:O08734 (PMID:16199525), (PMID:21041309), (PMID:9843949)
RGD PMID:9843949 PMID:10950869 PMID:16199525 PMID:21041309 PMID:18252800 MGI:5009197, RGD:2313987 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
MGI:108093|MGI:98834 (MGI:1203837|PMID:9560217), (MGI:2677915|PMID:12925707), (MGI:2681362|PMID:14623868), (MGI:3028818|PMID:14614769), (MGI:3042308|PMID:14963330), (MGI:3688960|PMID:17052454)
(PMID:16199525), (PMID:17052454), (PMID:25609812), (PMID:9843949)
PMID:21873635
RGD PMID:9560217 PMID:9843949 PMID:12925707 PMID:14614769 PMID:14623868 More... MGI:1203837 MGI:2677915 MGI:2681362 MGI:3028818 MGI:3042308 MGI:3688960, RGD:14394498, RGD:13792537 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in IBA
ISO
PMID:21873635
(PMID:11463392)
RGD PMID:11463392 PMID:21873635 RGD:13792537 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISS
ISO
PMID:9843949
(MGI:3700463|PMID:9843949)
RGD PMID:9843949 PMID:9843949 MGI:3700463, RGD:8554139 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in
acts_upstream_of_or_within
ISO (PMID:9843949)
MGI:99702 (MGI:3688960|PMID:17052454)
RGD PMID:9843949 PMID:17052454 MGI:3688960 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within
involved_in
IDA
ISO
(MGI:4940333|PMID:9873064)
MGI:2158671 (MGI:2137769|PMID:11369777)
(MGI:5619478|PMID:18084238)
(PMID:17052454)
RGD PMID:9873064 PMID:11369777 PMID:17052454 PMID:18084238 PMID:18252800 MGI:2137769 MGI:4940333 MGI:5619478, RGD:2313987 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO (PMID:27505430) RGD PMID:27505430 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Casp2 caspase 2 involved_in ISO (PMID:12065594) RGD PMID:12065594 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Cck cholecystokinin IDA RGD PMID:11964411 RGD:625521 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
JBrowse link
G Dnm1l dynamin 1-like involved_in ISO (PMID:20850011) RGD PMID:20850011 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Fis1 fission, mitochondrial 1 involved_in ISO (PMID:19864424) RGD PMID:19864424 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Ggct gamma-glutamyl cyclotransferase involved_in ISO (PMID:16765912) RGD PMID:16765912 NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IMP induces release following removal of NGF from sympathetic neurons RGD PMID:11301023 RGD:2290592 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:15504737 RGD:2298783 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mff mitochondrial fission factor involved_in ISO
IEA
(PMID:18353969)
GO_REF:0000107
RGD
Ensembl
PMID:18353969 GO_REF:0000107 NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within
involved_in
ISO MGI:2678372 (MGI:2675761|PMID:12952892)
(MGI:5009174|PMID:14699081)
RGD PMID:12952892 PMID:14699081 MGI:2675761 MGI:5009174 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Sfn stratifin involved_in ISO (PMID:11574543) RGD PMID:11574543 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO MGI:1857344|MGI:1857480 (MGI:3654558|PMID:10212301), (MGI:3691744|PMID:15642323) RGD PMID:10212301 PMID:15642323 MGI:3654558 MGI:3691744 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Timm50 translocase of inner mitochondrial membrane 50 acts_upstream_of_or_within ISO (PMID:15044455) RGD PMID:15044455 NCBI chr 1:83,574,872...83,582,769
Ensembl chr 1:83,556,757...83,582,793
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:99702 (MGI:3042308|PMID:14963330), (MGI:3574697|PMID:15483136) RGD PMID:14963330 PMID:15483136 MGI:3042308 MGI:3574697 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO (MGI:3574697|PMID:15483136) RGD PMID:15483136 MGI:3574697 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
release of matrix enzymes from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in ISO
ISS
(PMID:9843949)
GO_REF:0000024
RGD
UniProt
PMID:9843949 GO_REF:0000024 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20094
    cellular process 18691
      cell death 2260
        programmed cell death 2066
          apoptotic process 2009
            apoptotic mitochondrial changes 124
              mitochondrial fragmentation involved in apoptotic process 12
              regulation of mitochondrial membrane permeability involved in apoptotic process + 49
              release of cytochrome c from mitochondria + 65
              release of matrix enzymes from mitochondria 1
Path 2
Term Annotations click to browse term
  biological_process 20094
    cellular process 18691
      cellular component organization or biogenesis 6758
        cellular component organization 6506
          organelle organization 3660
            mitochondrion organization 600
              apoptotic mitochondrial changes 124
                mitochondrial fragmentation involved in apoptotic process 12
                regulation of mitochondrial membrane permeability involved in apoptotic process + 49
                release of cytochrome c from mitochondria + 65
                release of matrix enzymes from mitochondria 1
paths to the root