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ONTOLOGY REPORT - ANNOTATIONS

Term:intrinsic apoptotic signaling pathway in response to oxidative stress
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Accession:GO:0008631 term browser browse the term
Definition:The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.
Synonyms:exact_synonym: oxidative stress-induced intrinsic apoptotic signaling pathway
 related_synonym: induction of apoptosis by oxidative stress


show annotations for term's descendants           Sort by:
intrinsic apoptotic signaling pathway in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member IMP protein:altered expression:liver (rat) RGD PMID:29589772 RGD:14975297 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Arl6ip5 ARF like GTPase 6 interacting protein 5 involved_in ISO
IEA 		(PMID:18387645)
GO_REF:0000107 		RGD
Ensembl		 PMID:18387645 GO_REF:0000107 NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608 		JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO (PMID:12855558) RGD PMID:12855558 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:23568032), (PMID:23979599)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:23568032 PMID:23979599 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:16085184) 		GO_Central
RGD		 PMID:16085184 GO_REF:0000033 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Diablol1 diablo, IAP-binding mitochondrial protein like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:141,744,994...141,746,345
Ensembl chr 5:141,744,961...141,746,356 		JBrowse link
G Gpx1 glutathione peroxidase 1 acts_upstream_of_or_within ISO
IEA 		MGI:2158814 (PMID:11562367), (PMID:15663476)
GO_REF:0000107
MGI:2158814 (PMID:16373599) 		RGD
Ensembl		 PMID:11562367 PMID:15663476 PMID:16373599 GO_REF:0000107 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gskip GSK3B interacting protein involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:25920809) 		UniProt
Ensembl
RGD		 PMID:25920809 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:124,586,087...124,609,106
Ensembl chr 6:124,586,070...124,609,100 		JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:15659221 RGD:1641883 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G LOC134486345 serine/threonine-protein kinase 24-like involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		(PMID:21771788), (PMID:26095851)
GO_REF:0000107
GO_REF:0000033
(PMID:18948261) 		RGD
Ensembl
GO_Central		 PMID:18948261 PMID:21771788 PMID:26095851 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Mapt microtubule-associated protein tau IDA RGD PMID:12420308 RGD:8158111 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Melk maternal embryonic leucine zipper kinase acts_upstream_of_or_within ISO
IEA 		(PMID:18948261)
GO_REF:0000107 		RGD
Ensembl		 PMID:18948261 GO_REF:0000107 NCBI chr 5:63,336,151...63,396,254
Ensembl chr 5:58,540,449...58,600,937 		JBrowse link
G Nox1 NADPH oxidase 1 acts_upstream_of ISO
IEA 		MGI:3616995 (PMID:19661248)
GO_REF:0000107 		RGD
Ensembl		 PMID:19661248 GO_REF:0000107 NCBI chr  X:101,572,338...101,625,571
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:18541534) 		UniProt
Ensembl
RGD		 PMID:18541534 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO
IEA 		(PMID:21030605)
GO_REF:0000107 		RGD
Ensembl		 PMID:21030605 GO_REF:0000107 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Rnf7 ring finger protein 7 acts_upstream_of_or_within ISO (PMID:10082581) RGD PMID:10082581 NCBI chr 8:97,038,845...97,048,080
Ensembl chr 8:97,038,840...97,047,824 		JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO
IEA 		MGI:1857480 (PMID:15642323)
GO_REF:0000107 		RGD
Ensembl		 PMID:15642323 GO_REF:0000107 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Stk24 serine/threonine kinase 24 involved_in ISO
IEA
ISS 		(PMID:19604147)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:19604147 GO_REF:0000024 GO_REF:0000107 NCBI chr15:98,363,707...98,458,940
Ensembl chr15:98,365,791...98,460,553 		JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats acts_upstream_of_or_within
involved_in 		ISO
IBA 		MGI:3043446 (PMID:15271982)
GO_REF:0000033 		RGD
GO_Central		 PMID:15271982 GO_REF:0000033 NCBI chr 8:61,259,415...61,347,789
Ensembl chr 8:61,259,477...61,347,789 		JBrowse link
G Zfp622 zinc finger protein 622 involved_in ISO (PMID:21771788) RGD PMID:21771788 NCBI chr 2:78,205,655...78,224,888
Ensembl chr 2:76,335,609...76,493,898 		JBrowse link
intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map2k4 mitogen activated protein kinase kinase 4 involved_in ISO (PMID:24705900) RGD PMID:24705900 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO
IEA 		UniProtKB:O00506 (PMID:22652780)
GO_REF:0000107 		RGD
Ensembl		 PMID:22652780 GO_REF:0000107 NCBI chr 2:162,602,516...162,644,690
Ensembl chr 2:160,303,449...160,346,018 		JBrowse link
G Stk25 serine/threonine kinase 25 involved_in ISO
IEA 		UniProtKB:Q9BUL8 (PMID:22652780)
GO_REF:0000107 		RGD
Ensembl		 PMID:22652780 GO_REF:0000107 NCBI chr 9:101,609,218...101,621,458
Ensembl chr 9:94,161,836...94,174,244 		JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO
IEA 		(PMID:21177249)
GO_REF:0000107 		RGD
Ensembl		 PMID:21177249 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO UniProtKB:Q99LX0 (PMID:14652021) RGD PMID:14652021 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA 		(PMID:21177249), (PMID:23261939)
GO_REF:0000107 		RGD
Ensembl		 PMID:21177249 PMID:23261939 GO_REF:0000107 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car3 carbonic anhydrase 3 IMP RGD PMID:29559661 RGD:408427357 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:24947010) RGD PMID:24947010 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IMP
IEA 		(PMID:17579517)
GO_REF:0000107 		RGD
Ensembl		 PMID:17579517 PMID:17579517 GO_REF:0000107, RGD:8693356 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q99497 (PMID:24947010) 		Ensembl
RGD		 PMID:24947010 GO_REF:0000107 NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Trap1 TNF receptor-associated protein 1 involved_in IMP PMID:17579517 ParkinsonsUK-UCL PMID:17579517 RGD:8693356 NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981 		JBrowse link
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:24475098) RGD PMID:24475098 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:27525436 ARUK-UCL PMID:27525436 RGD:13601987 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of ISO (PMID:25590961) RGD PMID:25590961 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gpx1 glutathione peroxidase 1 acts_upstream_of_or_within ISO
IEA 		MGI:2158814 (PMID:16373599)
GO_REF:0000107 		RGD
Ensembl		 PMID:16373599 GO_REF:0000107 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15731106) 		Ensembl
RGD		 PMID:15731106 GO_REF:0000107 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA 		(PMID:23043106)
GO_REF:0000107 		RGD
Ensembl		 PMID:23043106 GO_REF:0000107 NCBI chr10:46,669,721...46,675,768
Ensembl chr10:46,170,167...46,176,267 		JBrowse link
G Matcap1 microtubule associated tyrosine carboxypeptidase 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:33,158,053...33,166,784
Ensembl chr19:33,158,056...33,166,445 		JBrowse link
G Mir29b1 microRNA 29b-1 involved_in ISO (PMID:19956414) RGD PMID:19956414 NCBI chr 4:60,618,334...60,618,414
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mir29b2 microRNA 29b-2 involved_in ISO (PMID:19956414) RGD PMID:19956414 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO
IEA 		(PMID:23043106)
GO_REF:0000107 		RGD
Ensembl		 PMID:23043106 GO_REF:0000107 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nme5 NME/NM23 family member 5 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:12788088) 		GO_Central
RGD		 PMID:12788088 GO_REF:0000033 NCBI chr18:26,163,558...26,180,742
Ensembl chr18:26,163,555...26,180,794 		JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO (PMID:15004034) RGD PMID:15004034 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of ISO (PMID:22523093) RGD PMID:22523093 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISO
ISS 		(PMID:26095851)
GO_REF:0000024 		RGD
UniProt		 PMID:26095851 GO_REF:0000024 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA 		(PMID:17317627)
GO_REF:0000107 		RGD
Ensembl		 PMID:17317627 GO_REF:0000107 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sod2 superoxide dismutase 2 involved_in ISO
IEA 		(PMID:12551919)
GO_REF:0000107 		RGD
Ensembl		 PMID:12551919 GO_REF:0000107 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in IMP
IEA
ISO 		PMID:23392669
GO_REF:0000107
UniProtKB:Q9ES19 (PMID:23392669) 		Ensembl
RGD		 PMID:23392669 PMID:23392669 GO_REF:0000107, RGD:10047168 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Cpe carboxypeptidase E IMP RGD PMID:25426952 RGD:405650601 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21752258) 		Ensembl
RGD		 PMID:21752258 GO_REF:0000107 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Fbxo7 F-box protein 7 acts_upstream_of
involved_in 		ISO
IEA 		(PMID:26310625)
GO_REF:0000107
(PMID:25029497) 		RGD
Ensembl		 PMID:25029497 PMID:26310625 GO_REF:0000107 NCBI chr 7:19,696,951...19,725,180
Ensembl chr 7:17,809,231...17,837,530 		JBrowse link
G Fgf2 fibroblast growth factor 2 IMP RGD PMID:25426952 RGD:405650601 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fzd1 frizzled class receptor 1 involved_in ISO (PMID:21752258) RGD PMID:21752258 NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISO
IEA 		(PMID:24899725)
GO_REF:0000107 		RGD
Ensembl		 PMID:24899725 GO_REF:0000107 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Il10 interleukin 10 involved_in ISO
IEA 		ComplexPortal:CPX-1134 (PMID:21857966)
GO_REF:0000107 		RGD
Ensembl		 PMID:21857966 GO_REF:0000107 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Nono non-POU domain containing, octamer-binding involved_in ISO
IEA 		(PMID:15790595)
GO_REF:0000107 		RGD
Ensembl		 PMID:15790595 GO_REF:0000107 NCBI chr  X:66,554,131...66,571,992
Ensembl chr  X:66,554,098...66,571,952 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO 		GO_REF:0000024
(PMID:24899725)
(PMID:15790595), (PMID:16632486), (PMID:23743200) 		ParkinsonsUK-UCL
RGD		 PMID:15790595 PMID:16632486 PMID:23743200 PMID:24899725 GO_REF:0000024 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA 		(PMID:16632486)
GO_REF:0000107 		RGD
Ensembl		 PMID:16632486 GO_REF:0000107 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
IGI
ISS 		(PMID:17314283)
(PMID:23858059)
GO_REF:0000107
PMID:23392669
GO_REF:0000024 		RGD
Ensembl
ParkinsonsUK-UCL		 PMID:17314283 PMID:23858059 PMID:23392669 GO_REF:0000024 GO_REF:0000107, RGD:10047168 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in ISO (PMID:23743200) RGD PMID:23743200 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549 		JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO
IEA 		(PMID:21752258)
GO_REF:0000107 		RGD
Ensembl		 PMID:21752258 GO_REF:0000107 NCBI chr 7:131,817,558...131,821,605
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
neuron intrinsic apoptotic signaling pathway in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Daxx death-domain associated protein involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q99683 (PMID:15983381) 		Ensembl
RGD		 PMID:15983381 GO_REF:0000107 NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO
IEA 		UniProtKB:Q9UER7 (PMID:15983381)
GO_REF:0000107 		RGD
Ensembl		 PMID:15983381 GO_REF:0000107 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nox1 NADPH oxidase 1 acts_upstream_of_or_within ISO
IEA 		MGI:3616995 (PMID:19661248)
GO_REF:0000107 		RGD
Ensembl		 PMID:19661248 GO_REF:0000107 NCBI chr  X:101,572,338...101,625,571
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (PMID:22555455) RGD PMID:22555455 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Sfpq splicing factor proline and glutamine rich involved_in ISO
IEA 		(PMID:15790595)
GO_REF:0000107 		RGD
Ensembl		 PMID:15790595 GO_REF:0000107 NCBI chr 5:144,621,678...144,637,930
Ensembl chr 5:139,338,075...139,353,472 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISO
IEA 		(PMID:12551919)
GO_REF:0000107 		RGD
Ensembl		 PMID:12551919 GO_REF:0000107 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Vnn1 vanin 1 involved_in ISO
IEA 		(PMID:15282320)
GO_REF:0000107 		RGD
Ensembl		 PMID:15282320 GO_REF:0000107 NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:21,537,094...21,547,395 		JBrowse link
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:28386847 RGD:329337357 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO
IEA 		(PMID:23858059)
GO_REF:0000107 		RGD
Ensembl		 PMID:23858059 GO_REF:0000107 NCBI chr 2:172,447,738...172,609,591
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO UniProtKB:Q9WVS6 (PMID:23858059) RGD PMID:23858059 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IMP RGD PMID:27614125 RGD:329961568 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Ralbp1 ralA binding protein 1 IMP RGD PMID:23788031 RGD:12904719 NCBI chr 9:112,903,289...112,940,093
Ensembl chr 9:105,456,425...105,492,707 		JBrowse link
regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P4hb prolyl 4-hydroxylase subunit beta involved_in ISO
IEA 		(PMID:12095988)
GO_REF:0000107 		RGD
Ensembl		 PMID:12095988 GO_REF:0000107 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:12095988)
GO_REF:0000107 		HGNC
RGD
Ensembl		 PMID:12095988 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090 		JBrowse link
regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:15983381) RGD PMID:15983381 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IMP RGD PMID:17347665 RGD:10414071 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Prodh proline dehydrogenase involved_in ISO (PMID:23743200) RGD PMID:23743200 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30684126) RGD PMID:30684126 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      signal transduction 7313
        apoptotic signaling pathway 688
          intrinsic apoptotic signaling pathway 349
            intrinsic apoptotic signaling pathway in response to oxidative stress 70
              intrinsic apoptotic signaling pathway in response to hydrogen peroxide + 9
              negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 34
              neuron intrinsic apoptotic signaling pathway in response to oxidative stress + 25
              positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 10
              regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 48
Path 2
Term Annotations click to browse term
  biological_process 20543
    biological regulation 13835
      regulation of biological process 13398
        regulation of cellular process 13032
          signal transduction 7313
            apoptotic signaling pathway 688
              intrinsic apoptotic signaling pathway 349
                intrinsic apoptotic signaling pathway in response to oxidative stress 70
                  intrinsic apoptotic signaling pathway in response to hydrogen peroxide + 9
                  negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 34
                  neuron intrinsic apoptotic signaling pathway in response to oxidative stress + 25
                  positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 10
                  regulation of oxidative stress-induced intrinsic apoptotic signaling pathway + 48
paths to the root