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ONTOLOGY REPORT - ANNOTATIONS


Term:attachment of spindle microtubules to kinetochore
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Accession:GO:0008608 term browser browse the term
Definition:The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex.
Comment:This class covers all attachments of spindle microtubules to the kinetochore, including the many incorrect attachments which initially form and are later corrected to stable attachments with the correct orientation for segregation to proceed (sister chromatid biorientation).
Synonyms:exact_synonym: attachment of spindle microtubules to chromosome;   kinetochore-microtubule attachment;   microtubule anchoring at kinetochore;   spindle chromosome attachment;   spindle kinetochore attachment
 narrow_synonym: microtubule capture
 broad_synonym: kinetochore microtubule interaction;   microtubule and chromosome interaction;   spindle-chromosome interaction
 related_synonym: amphotelic attachment;   bipolar attachment;   microtubule and kinetochore interaction
 alt_id: GO:0051313



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attachment of spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas1 BRCA1 A complex subunit involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 5:100,804,802...100,845,864
Ensembl chr 5:100,805,192...100,820,965
JBrowse link
G Abraxas2 BRISC complex subunit involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 7:132,859,225...132,885,114
Ensembl chr 7:132,859,225...132,885,111
JBrowse link
G Bub3 BUB3 mitotic checkpoint protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:131,560,367...131,571,895
Ensembl chr 7:131,560,222...131,571,895
JBrowse link
G Cenpe centromere protein E involved_in
acts_upstream_of_or_within
IMP
TAS
(MGI:2673075|PMID:12925705)
(MGI:2388532|PMID:12147697)
UniProt
MGI
PMID:12147697 PMID:12925705 MGI:2388532 MGI:2673075 NCBI chr 3:135,212,563...135,273,540
Ensembl chr 3:135,212,537...135,273,611
JBrowse link
G Eml4 echinoderm microtubule associated protein like 4 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:83,350,930...83,480,361
Ensembl chr17:83,350,931...83,480,361
JBrowse link
G Knl1 kinetochore scaffold 1 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 2:119,047,119...119,110,497
Ensembl chr 2:119,047,119...119,105,501
JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:71,496,100...71,526,857
Ensembl chr17:71,496,100...71,526,857
JBrowse link
G Nuf2 NUF2, NDC80 kinetochore complex component acts_upstream_of_or_within ISO MGI GO_REF:0000008 MGI:2154458 NCBI chr 1:169,497,934...169,531,464
Ensembl chr 1:169,497,934...169,531,464
JBrowse link
G Sgo1 shugoshin 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:53,674,786...53,691,331
Ensembl chr17:53,674,786...53,689,333
JBrowse link
G Tex14 testis expressed gene 14 involved_in IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:5318128|PMID:22405274)
GO_Central
UniProt
PMID:21873635 PMID:22405274 MGI:5318128 MGI:6201960 NCBI chr11:87,405,013...87,555,823
Ensembl chr11:87,405,065...87,555,823
JBrowse link
G Zfp207 zinc finger protein 207 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr11:80,383,279...80,408,561
Ensembl chr11:80,383,279...80,405,733
JBrowse link
attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:122,568,015...122,573,130
Ensembl chr 8:122,568,015...122,573,554
JBrowse link
G Cenpc1 centromere protein C1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 5:86,012,018...86,065,962
Ensembl chr 5:86,012,024...86,065,583
JBrowse link
G Cenpe centromere protein E involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:135,212,563...135,273,540
Ensembl chr 3:135,212,537...135,273,611
JBrowse link
G Champ1 chromosome alignment maintaining phosphoprotein 1 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 8:13,869,641...13,881,639
Ensembl chr 8:13,869,641...13,881,639
JBrowse link
G Kif2c kinesin family member 2C involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:117,159,633...117,182,624
Ensembl chr 4:117,159,639...117,182,639
JBrowse link
G Mad1l1 MAD1 mitotic arrest deficient 1-like 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 5:140,008,689...140,321,608
Ensembl chr 5:140,008,689...140,321,552
JBrowse link
G Mis12 MIS12 kinetochore complex component involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:71,019,568...71,027,371
Ensembl chr11:71,019,611...71,027,371
JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr17:71,496,100...71,526,857
Ensembl chr17:71,496,100...71,526,857
JBrowse link
G Nuf2 NUF2, NDC80 kinetochore complex component involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 1:169,497,934...169,531,464
Ensembl chr 1:169,497,934...169,531,464
JBrowse link
G Seh1l SEH1-like (S. cerevisiae involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:67,774,876...67,795,487
Ensembl chr18:67,774,876...67,795,487
JBrowse link
homologous chromosome orientation involved in meiotic metaphase I plate congression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 breast cancer 2, early onset involved_in ISO RGD
MGI
PMID:16964288 GO_REF:0000096 MGI:4417868 RGD:1599505 NCBI chr 5:150,522,297...150,570,147
Ensembl chr 5:150,522,630...150,570,329
JBrowse link
lateral attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpe centromere protein E involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:135,212,563...135,273,540
Ensembl chr 3:135,212,537...135,273,611
JBrowse link
mitotic sister chromatid biorientation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bod1 biorientation of chromosomes in cell division 1 involved_in ISO (PMID:17938248), (PMID:24157919) UniProt PMID:17938248 PMID:24157919 NCBI chr11:31,665,150...31,671,862
Ensembl chr11:31,665,181...31,671,885
JBrowse link
monopolar spindle attachment to meiosis I kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpc1 centromere protein C1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 5:86,012,018...86,065,962
Ensembl chr 5:86,012,024...86,065,583
JBrowse link
positive regulation of attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1, autophagy related involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:101,288,258...101,302,286
Ensembl chr11:101,285,952...101,302,286
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 1:178,321,108...178,338,891
Ensembl chr 1:178,321,108...178,337,797
JBrowse link
positive regulation of attachment of spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1 cyclin B1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:100,778,739...100,786,486
Ensembl chr13:100,778,650...100,786,570
JBrowse link
G Cenpe centromere protein E involved_in IMP (MGI:2447982|PMID:12361599) UniProt PMID:12361599 MGI:2447982 NCBI chr 3:135,212,563...135,273,540
Ensembl chr 3:135,212,537...135,273,611
JBrowse link
G Rcc2 regulator of chromosome condensation 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:140,701,473...140,723,220
Ensembl chr 4:140,700,541...140,723,220
JBrowse link
G Sirt2 sirtuin 2 involved_in IMP (MGI:5567889|PMID:24334550) UniProt PMID:24334550 MGI:5567889 NCBI chr 7:28,766,752...28,788,665
Ensembl chr 7:28,766,735...28,788,661
JBrowse link
positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:69,045,624...69,051,664
Ensembl chr11:69,045,647...69,051,664
JBrowse link
regulation of attachment of spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC, WNT signaling pathway regulator acts_upstream_of_or_within ISO
IMP
(MGI:3701148|PMID:17227893) MGI PMID:17227893 GO_REF:0000008 MGI:2154458 MGI:3701148 NCBI chr18:34,220,297...34,322,190
Ensembl chr18:34,220,924...34,322,552
JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:137,319,696...137,357,759
Ensembl chr 4:137,319,696...137,357,720
JBrowse link
G Ect2 ect2 oncogene involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 3:27,097,222...27,154,253
Ensembl chr 3:27,097,222...27,153,878
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 2:118,813,988...118,837,210
Ensembl chr 2:118,814,003...118,853,957
JBrowse link
G Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:191,821,449...191,833,049
Ensembl chr 1:191,821,444...191,833,050
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:99,620,496...99,651,656
Ensembl chr15:99,620,496...99,651,656
JBrowse link
G Spag5 sperm associated antigen 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:78,301,470...78,322,457
Ensembl chr11:78,301,529...78,322,457
JBrowse link
sister chromatid biorientation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Champ1 chromosome alignment maintaining phosphoprotein 1 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 8:13,869,641...13,881,639
Ensembl chr 8:13,869,641...13,881,639
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr14:73,192,858...73,325,951
Ensembl chr14:73,183,673...73,325,822
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28616
    cellular process 17624
      cell cycle process 1174
        attachment of spindle microtubules to kinetochore 34
          attachment of mitotic spindle microtubules to kinetochore + 14
          attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation + 2
          negative regulation of attachment of spindle microtubules to kinetochore + 0
          positive regulation of attachment of spindle microtubules to kinetochore + 7
          regulation of attachment of spindle microtubules to kinetochore + 14
          sister chromatid biorientation + 3
Path 2
Term Annotations click to browse term
  biological_process 28616
    cellular process 17624
      cell cycle 1591
        cell cycle process 1174
          nuclear chromosome segregation 279
            attachment of spindle microtubules to kinetochore 34
              attachment of mitotic spindle microtubules to kinetochore + 14
              attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation + 2
              negative regulation of attachment of spindle microtubules to kinetochore + 0
              positive regulation of attachment of spindle microtubules to kinetochore + 7
              regulation of attachment of spindle microtubules to kinetochore + 14
              sister chromatid biorientation + 3
paths to the root