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ONTOLOGY REPORT - ANNOTATIONS


Term:secondary active organic cation transmembrane transporter activity
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Accession:GO:0008513 term browser browse the term
Definition:Enables the transfer of organic cations from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
Synonyms:narrow_synonym: polyspecific organic cation transmembrane transporter activity
 related_synonym: organic cation porter activity
 alt_id: GO:0015354
 xref: reactome:R-HSA-549241 "SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol"



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secondary active organic cation transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC22A4 solute carrier family 22 member 4 enables TAS Reactome Reactome:R-HSA-549241 NCBI chr 5:132,294,394...132,344,190
Ensembl chr 5:132,294,394...132,344,190
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Path 1
Term Annotations click to browse term
  molecular_function 19691
    transporter activity 1301
      transmembrane transporter activity 1179
        organic cation transmembrane transporter activity 85
          secondary active organic cation transmembrane transporter activity 1
Path 2
Term Annotations click to browse term
  molecular_function 19691
    transporter activity 1301
      transmembrane transporter activity 1179
        active transmembrane transporter activity 465
          secondary active transmembrane transporter activity 292
            secondary active organic cation transmembrane transporter activity 1
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