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ONTOLOGY REPORT - ANNOTATIONS

Term:protein-tyrosine sulfotransferase activity
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Accession:GO:0008476 term browser browse the term
Definition:Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate.
Synonyms:exact_synonym: protein-tyrosine sulphotransferase activity
 related_synonym: 3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase activity;   tyrosylprotein sulfotransferase activity
 xref: EC:2.8.2.20;   MetaCyc:PROTEIN-TYROSINE-SULFOTRANSFERASE-RXN;   RHEA:16801;   Reactome:R-HSA-9668023 "TPST1,2 transfer SO4(2-) from PAPS to FVIII";   Reactome:R-HSA-9668148 "F8 variant is not sulfonated at Y1699";   reactome:R-HSA-8954262 "TPST1,2 transfer SO4(2-) from PAPS to PODXL2"


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protein-tyrosine sulfotransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpst1 tyrosylprotein sulfotransferase 1 enables ISO
IEA
ISS
IBA		 (PMID:9501187)
GO_REF:0000003
GO_REF:0000024
GO_REF:0000117
GO_REF:0000033
MGI:2183366 (PMID:17046811), (PMID:9501187)		 RGD
UniProt
GO_Central		 PMID:9501187 PMID:17046811 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000117 NCBI chr12:26,544,536...26,605,706
Ensembl chr12:26,544,536...26,605,704 		JBrowse link
G Tpst2 tyrosylprotein sulfotransferase 2 enables ISO
IBA
IEA
ISS		 (PMID:23481380), (PMID:9733778)
MGI:3512111 (PMID:17046811), (PMID:9733778)
GO_REF:0000033
GO_REF:0000117
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:9733778 PMID:17046811 PMID:23481380 GO_REF:0000024 GO_REF:0000033 GO_REF:0000117 NCBI chr12:44,321,875...44,363,892
Ensembl chr12:44,321,875...44,362,329 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      catalytic activity, acting on a protein 2509
        protein-tyrosine sulfotransferase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      transferase activity 2397
        transferase activity, transferring sulphur-containing groups 78
          sulfotransferase activity 58
            protein-tyrosine sulfotransferase activity 2
paths to the root