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ONTOLOGY REPORT - ANNOTATIONS

Term:GDP-mannose 4,6-dehydratase activity
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Accession:GO:0008446 term browser browse the term
Definition:Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H2O.
Synonyms:related_synonym: GDP-D-mannose 4,6-dehydratase activity;   GDP-D-mannose dehydratase activity;   GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming);   GDP-mannose 4,6-hydro-lyase activity;   GDPmannose 4,6-dehydratase activity;   Gmd;   guanosine 5'-diphosphate-D-mannose oxidoreductase activity;   guanosine diphosphomannose 4,6-dehydratase activity;   guanosine diphosphomannose oxidoreductase activity
 xref: EC:4.2.1.47;   KEGG_REACTION:R00888;   MetaCyc:GDPMANDEHYDRA-RXN;   RHEA:23820;   reactome:R-HSA-6787632 "GMDS dehydrates GDP-Man to GDP-DHDMan"


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GDP-mannose 4,6-dehydratase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gmds GDP-mannose 4, 6-dehydratase enables ISS
ISO
IBA		 GO_REF:0000024
UniProtKB:Q8K3X3 (PMID:9525924), (PMID:9603974)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:9525924 PMID:9603974 GO_REF:0000024 GO_REF:0000033 NCBI chr17:32,095,315...32,621,975
Ensembl chr17:32,095,386...32,621,961 		JBrowse link
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  molecular_function 20890
    catalytic activity 6118
      lyase activity 214
        carbon-oxygen lyase activity 91
          hydro-lyase activity 71
            GDP-mannose 4,6-dehydratase activity 1
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