Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:sterol 14-demethylase activity
go back to main search page
Accession:GO:0008398 term browser browse the term
Definition:Catalysis of the reaction: a 14alpha-methyl steroid + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = a delta14 steroid + formate + 4 H+ + 4 H2O + 3 oxidized [NADPH-hemoprotein reductase].
Synonyms:narrow_synonym: cytochrome P450 51 activity;   cytochrome P450 CYP51;   lanosterol 14-alpha-demethylase activity;   lanosterol 14-demethylase activity;   obtusufoliol 14-demethylase activity
 related_synonym: lanosterol 14alpha-demethylase activity;   sterol 14-alpha-demethylase activity;   sterol 14alpha-demethylase activity
 xref: EC:1.14.14.154;   MetaCyc:1.14.13.70-RXN;   RHEA:54028


show annotations for term's descendants           Sort by:
sterol 14-demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 enables ISO
IEA		 RGD
Ensembl		 PMID:7581240 PMID:7665087 GO_REF:0000107 RGD:1298863 RGD:2316902 NCBI chr14:17,746,654...17,767,019
Ensembl chr14:17,746,656...17,766,658 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21949
    catalytic activity 5721
      demethylase activity 42
        sterol 14-demethylase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21949
    catalytic activity 5721
      oxidoreductase activity 775
        monooxygenase activity 113
          oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 29
            sterol 14-demethylase activity 1
paths to the root