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ONTOLOGY REPORT - ANNOTATIONS

Term:steroid 7-alpha-hydroxylase activity
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Accession:GO:0008387 term browser browse the term
Definition:Catalysis of the reaction: a steroid + AH2 + O2 = 7-alpha-hydroxysteroid + H2O.
Synonyms:narrow_synonym: cytochrome P450 CYP2A12


show annotations for term's descendants           Sort by:
steroid 7-alpha-hydroxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 enables ISO (PMID:10748047) RGD PMID:10748047 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775 		JBrowse link
24S-hydroxycholesterol 7-alpha-hydroxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
25-hydroxycholesterol 7-alpha-hydroxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:100,502,791...100,669,698 		JBrowse link
cholesterol 7-alpha-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 enables ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 enables IDA
ISO
IBA		 (PMID:11279518), (PMID:12114517), (PMID:15845870)
GO_REF:0000033
PMID:1694852
(PMID:12077124)		 RGD
GO_Central		 PMID:11279518 PMID:12077124 PMID:12114517 PMID:15845870 PMID:2335522 More... GO_REF:0000033, RGD:70535, RGD:70534 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
oxysterol 7-alpha-hydroxylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 enables TAS
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:12029625 GO_REF:0000033, RGD:1298868 NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:100,502,791...100,669,698 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      oxidoreductase activity 869
        oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 244
          steroid 7-alpha-hydroxylase activity 4
            24S-hydroxycholesterol 7-alpha-hydroxylase activity 1
            25-hydroxycholesterol 7-alpha-hydroxylase activity 1
            cholesterol 7-alpha-monooxygenase activity 2
            oxysterol 7-alpha-hydroxylase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      oxidoreductase activity 869
        monooxygenase activity 165
          steroid hydroxylase activity 36
            steroid 7-alpha-hydroxylase activity 4
              24S-hydroxycholesterol 7-alpha-hydroxylase activity 1
              25-hydroxycholesterol 7-alpha-hydroxylase activity 1
              cholesterol 7-alpha-monooxygenase activity 2
              oxysterol 7-alpha-hydroxylase activity 2
paths to the root