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ONTOLOGY REPORT - ANNOTATIONS

Term:determination of adult lifespan
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Accession:GO:0008340 term browser browse the term
Definition:The pathways that regulate the duration of the adult phase of the life-cycle of an animal.


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determination of adult lifespan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankle1 ankyrin repeat and LEM domain containing 1 NOT|involved_in ISO (MGI:5800654|PMID:27010503) RGD PMID:27010503 MGI:5800654 NCBI chr16:18,076,413...18,082,356
Ensembl chr16:18,076,492...18,083,729 		JBrowse link
G Atm ATM serine/threonine kinase acts_upstream_of_or_within ISO MGI:3605986|MGI:894697 (MGI:3836659|PMID:19061978) RGD PMID:19061978 MGI:3836659 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atn1 atrophin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:4360645 (MGI:4359552|PMID:19681162)
GO_REF:0000107		 RGD
Ensembl		 PMID:19681162 GO_REF:0000107 MGI:4359552 NCBI chr 4:157,554,287...157,568,092
Ensembl chr 4:157,551,276...157,568,132 		JBrowse link
G Atp8a2 ATPase phospholipid transporting 8A2 acts_upstream_of_or_within ISO MGI:1856273 (MGI:60062|PMID:1634998) RGD PMID:1634998 MGI:60062 NCBI chr15:33,817,309...34,350,193
Ensembl chr15:33,819,755...34,350,223 		JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 acts_upstream_of_or_within ISO MGI:1351641 (MGI:5439233|PMID:22867887) RGD PMID:22867887 MGI:5439233 NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISO UniProtKB:P02340 (MGI:4944151|PMID:20818388) RGD PMID:20818388 MGI:4944151 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Cfh complement factor H acts_upstream_of_or_within ISO (MGI:5883383|PMID:28057640) RGD PMID:28057640 MGI:5883383 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Cgas cyclic GMP-AMP synthase acts_upstream_of_or_within ISO MGI:1328317 (MGI:5699498|PMID:26371324) RGD PMID:26371324 MGI:5699498 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Coq7 coenzyme Q7, hydroxylase involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:2157003 (MGI:4359329|PMID:19478076)		 RGD PMID:19478076 PMID:21873635 MGI:4359329, RGD:13792537 NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:172,835,188...172,851,158 		JBrowse link
G Dmd dystrophin acts_upstream_of_or_within ISO MGI:1342270 (MGI:5515277|PMID:23798567) RGD PMID:23798567 MGI:5515277 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:1857079|MGI:3785162|MGI:6402836 (MGI:5515276|PMID:23798568), (MGI:5704242|PMID:26624227), (MGI:6101307|PMID:24770645), (MGI:6282476|PMID:28798354) RGD PMID:23798568 PMID:24770645 PMID:26624227 PMID:28798354 MGI:5515276 MGI:5704242 MGI:6101307 MGI:6282476 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within ISO MGI:2183944 (MGI:3696605|PMID:17183314) RGD PMID:17183314 MGI:3696605 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit acts_upstream_of_or_within ISO MGI:2183949 (MGI:2179786|PMID:11950998), (MGI:3692802|PMID:17020410) RGD PMID:11950998 PMID:17020410 MGI:2179786 MGI:3692802 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease acts_upstream_of_or_within ISO MGI:3043589 (MGI:3041918|PMID:15082767) RGD PMID:15082767 MGI:3041918 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472 		JBrowse link
G Gba glucosylceramidase beta acts_upstream_of_or_within ISO (MGI:3795074|PMID:18346921) RGD PMID:18346921 MGI:3795074 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Ghrhr growth hormone releasing hormone receptor acts_upstream_of_or_within ISO MGI:1856425 (MGI:2135699|PMID:11371619) RGD PMID:11371619 MGI:2135699 NCBI chr 4:84,498,159...84,532,847
Ensembl chr 4:84,500,212...84,532,776 		JBrowse link
G Hdac9 histone deacetylase 9 acts_upstream_of_or_within ISO MGI:1890508 (MGI:5139938|PMID:21746928) RGD PMID:21746928 MGI:5139938 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333 		JBrowse link
G Htt huntingtin acts_upstream_of_or_within ISO MGI:2177757|MGI:2177767|MGI:2177768 (MGI:1926691|PMID:11062468), (MGI:1929816|PMID:11152661) RGD PMID:11062468 PMID:11152661 MGI:1926691 MGI:1929816 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Icmt isoprenylcysteine carboxyl methyltransferase acts_upstream_of_or_within ISO MGI:1890508 (MGI:5500993|PMID:23686339) RGD PMID:23686339 MGI:5500993 NCBI chr 5:162,804,368...162,811,129
Ensembl chr 5:162,804,368...162,811,128 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2386884 (MGI:1266928|PMID:9620849)		 Ensembl
RGD		 PMID:9620849 GO_REF:0000107 MGI:1266928 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 acts_upstream_of_or_within ISO MGI:1100508 (MGI:3693423|PMID:16501027) RGD PMID:16501027 MGI:3693423 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 acts_upstream_of_or_within ISO MGI:107501 (MGI:3693423|PMID:16501027) RGD PMID:16501027 MGI:3693423 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603 		JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO MGI:5607735|MGI:6488172|MGI:98246|MGI:98248 (MGI:4947196|PMID:21156207), (MGI:5561131|PMID:24719109), (MGI:6487992|PMID:32239694) RGD PMID:21156207 PMID:24719109 PMID:32239694 MGI:4947196 MGI:5561131 MGI:6487992 NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071 		JBrowse link
G Kl Klotho acts_upstream_of_or_within ISO MGI:1889570 (MGI:1099360|PMID:9363890) RGD PMID:9363890 MGI:1099360 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
G Large1 LARGE xylosyl- and glucuronyltransferase 1 acts_upstream_of_or_within ISO MGI:94909 (MGI:5515277|PMID:23798567), (MGI:5585386|PMID:24722207) RGD PMID:23798567 PMID:24722207 MGI:5515277 MGI:5585386 NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930 		JBrowse link
G Lep leptin acts_upstream_of_or_within ISO MGI:1328317 (MGI:5829115|PMID:28069950) RGD PMID:28069950 MGI:5829115 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2451080 (MGI:5702564|PMID:25147230)
GO_REF:0000107		 RGD
Ensembl		 PMID:25147230 GO_REF:0000107 MGI:5702564 NCBI chr 1:232,024,351...232,167,329
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:19692353) RGD PMID:19692353 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Meg3 maternally expressed 3 acts_upstream_of_or_within ISO MGI:3842511 (MGI:3841506|PMID:19264764) RGD PMID:19264764 MGI:3841506 NCBI chr 6:128,491,808...128,524,010 JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1858055 (MGI:1351797|PMID:10545954)		 Ensembl
RGD		 PMID:10545954 GO_REF:0000107 MGI:1351797 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO MGI:1858014|MGI:2151803 (MGI:1100204|PMID:9390556), (MGI:1351797|PMID:10545954) RGD PMID:9390556 PMID:10545954 MGI:1100204 MGI:1351797 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1342057|MGI:1350341|MGI:1934018 (MGI:5439233|PMID:22867887), (MGI:5621235|PMID:25524704), (MGI:5819191|PMID:26147524), (MGI:6219748|PMID:26607664) RGD PMID:22867887 PMID:25524704 PMID:26147524 PMID:26607664 MGI:5439233 MGI:5621235 MGI:5819191 MGI:6219748 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Polg DNA polymerase gamma, catalytic subunit acts_upstream_of_or_within ISO MGI:3046825 (MGI:3045911|PMID:15164064) RGD PMID:15164064 MGI:3045911 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO MGI:1856024|MGI:1856025 (MGI:2135699|PMID:11371619) RGD PMID:11371619 MGI:2135699 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
G Prdm2 PR/SET domain 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2388354 (MGI:2149923|PMID:11544182)		 Ensembl
RGD		 PMID:11544182 GO_REF:0000107 MGI:2149923 NCBI chr 5:155,421,066...155,531,884
Ensembl chr 5:155,422,134...155,531,825 		JBrowse link
G Rad54b RAD54 homolog B acts_upstream_of_or_within ISO MGI:107202|MGI:894697 (MGI:3836659|PMID:19061978) RGD PMID:19061978 MGI:3836659 NCBI chr 5:25,030,885...25,104,616
Ensembl chr 5:25,032,066...25,104,616 		JBrowse link
G Rad54l RAD54 like acts_upstream_of_or_within ISO MGI:107202|MGI:3605986 (MGI:3836659|PMID:19061978) RGD PMID:19061978 MGI:3836659 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070 		JBrowse link
G Scn1a sodium voltage-gated channel alpha subunit 1 acts_upstream_of_or_within ISO MGI:1309503|MGI:4458373|MGI:98248 (MGI:4947196|PMID:21156207) RGD PMID:21156207 MGI:4947196 NCBI chr 3:50,952,790...51,071,804
Ensembl chr 3:50,952,791...51,071,699 		JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 acts_upstream_of_or_within ISO MGI:1309503|MGI:98246 (MGI:4947196|PMID:21156207) RGD PMID:21156207 MGI:4947196 NCBI chr 3:50,302,781...50,437,504
Ensembl chr 3:50,302,877...50,437,214 		JBrowse link
G Sgsh N-sulfoglucosamine sulfohydrolase acts_upstream_of_or_within ISO MGI:1351641 (MGI:5439233|PMID:22867887) RGD PMID:22867887 MGI:5439233 NCBI chr10:104,596,810...104,613,510
Ensembl chr10:104,598,112...104,613,486 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:25541994)
(MGI:7258357|PMID:31002797)		 RGD PMID:25541994 PMID:31002797 MGI:7258357 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Sod1 superoxide dismutase 1 acts_upstream_of_or_within ISO MGI:1857872 (MGI:3640408|PMID:16377630) RGD PMID:16377630 MGI:3640408 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase acts_upstream_of_or_within ISO MGI:1890508 (MGI:5913114|PMID:23695662) RGD PMID:23695662 MGI:5913114 NCBI chr  X:14,421,028...14,434,216
Ensembl chr  X:14,421,109...14,433,982 		JBrowse link
G Suv39h1-ps1 SUV39H1 histone lysine methyltransferase, pseudogene 1 acts_upstream_of_or_within ISO MGI:1890508 (MGI:5913114|PMID:23695662) RGD PMID:23695662 MGI:5913114 NCBI chr  X:141,793,695...141,795,558 JBrowse link
G Terc telomerase RNA component acts_upstream_of_or_within ISO MGI:109635 (MGI:3050262|PMID:15235603) RGD PMID:15235603 MGI:3050262 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Tfcp2l1 transcription factor CP2-like 1 acts_upstream_of_or_within ISO MGI:3707684 (MGI:3703120|PMID:17079272) RGD PMID:17079272 MGI:3703120 NCBI chr13:29,733,813...29,793,870
Ensembl chr13:29,733,840...29,793,870 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO (MGI:4944151|PMID:20818388) RGD PMID:20818388 MGI:4944151 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO MGI:2385473 (MGI:3588617|PMID:16107615) RGD PMID:16107615 MGI:3588617 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:104663|MGI:2442261|MGI:3052754 (MGI:3052278|PMID:15254239), (MGI:5699498|PMID:26371324), (MGI:5829115|PMID:28069950) RGD PMID:15254239 PMID:26371324 PMID:28069950 MGI:3052278 MGI:5699498 MGI:5829115 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Wrn WRN RecQ like helicase acts_upstream_of_or_within ISO MGI:109558 (MGI:3050262|PMID:15235603) RGD PMID:15235603 MGI:3050262 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:1099440|MGI:1888594|MGI:1931221|MGI:2180033 (MGI:2178865|PMID:11923874), (MGI:3583382|PMID:15980864), (MGI:3789238|PMID:16079796), (MGI:3797328|PMID:18443001), (MGI:5139938|PMID:21746928), (MGI:5500993|PMID:23686339), (MGI:5824440|PMID:27799555), (MGI:5913114|PMID:23695662) RGD PMID:11923874 PMID:15980864 PMID:16079796 PMID:18443001 PMID:21746928 More... MGI:2178865 MGI:3583382 MGI:3789238 MGI:3797328 MGI:5139938 MGI:5500993 MGI:5824440 MGI:5913114 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110 		JBrowse link
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  biological_process 19738
    multicellular organismal process 9179
      determination of adult lifespan 51
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