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ONTOLOGY REPORT - ANNOTATIONS

Term:endosome to lysosome transport
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Accession:GO:0008333 term browser browse the term
Definition:The directed movement of substances from endosomes to lysosomes.


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endosome to lysosome transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aktip AKT interacting protein involved_in ISO
IEA
ISS		 (PMID:18799622)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:18799622 GO_REF:0000024 GO_REF:0000107 NCBI chr19:15,866,811...15,877,123
Ensembl chr19:15,866,928...15,886,663 		JBrowse link
G Atg14 autophagy related 14 acts_upstream_of_or_within ISO UniProtKB:O95295 (PMID:22797916) RGD PMID:22797916 NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113 		JBrowse link
G Becn2 beclin 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:23954414)
(MGI:5528919|PMID:23954414)		 RGD PMID:23954414 MGI:5528919 NCBI chr13:87,842,980...87,892,410
Ensembl chr13:87,844,531...87,845,787 		JBrowse link
G Bin1 bridging integrator 1 involved_in ISO
IEA		 (PMID:27179792)
GO_REF:0000107		 RGD
Ensembl		 PMID:27179792 GO_REF:0000107 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263 		JBrowse link
G Cdx2 caudal type homeo box 2 acts_upstream_of_or_within ISO (MGI:4457791|PMID:20551175) RGD PMID:20551175 MGI:4457791 NCBI chr12:7,726,798...7,733,142
Ensembl chr12:7,726,798...7,733,142 		JBrowse link
G Chmp3 charged multivesicular body protein 3 IMP RGD PMID:18076377 RGD:4892661 NCBI chr 4:103,576,453...103,622,566
Ensembl chr 4:103,576,515...103,623,959 		JBrowse link
G Chmp5 charged multivesicular body protein 5 acts_upstream_of_or_within ISO MGI:3626293 (MGI:3622513|PMID:16567502) RGD PMID:16567502 MGI:3622513 NCBI chr 5:56,081,385...56,098,529
Ensembl chr 5:56,081,343...56,098,529 		JBrowse link
G Clec16a C-type lectin domain containing 16A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:4,927,799...5,123,749
Ensembl chr10:4,928,030...5,123,578 		JBrowse link
G Dennd3 DENN domain containing 3 involved_in ISO (MGI:5448516|PMID:21718402) RGD PMID:21718402 MGI:5448516 NCBI chr 7:105,415,870...105,473,583
Ensembl chr 7:105,415,677...105,473,592 		JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L involved_in ISO (PMID:24790097) RGD PMID:24790097 NCBI chr11:64,814,926...64,824,539
Ensembl chr11:64,814,926...64,824,538 		JBrowse link
G Epg5 ectopic P-granules 5 autophagy tethering factor involved_in ISO (PMID:29130391) RGD PMID:29130391 NCBI chr18:71,403,990...71,502,079
Ensembl chr18:71,404,010...71,501,502 		JBrowse link
G Fhip1b FHF complex subunit HOOK interacting protein 1B involved_in ISO
IEA
ISS
IBA		 (PMID:18799622)
GO_REF:0000107
GO_REF:0000024
PMID:21873635		 RGD
Ensembl
UniProt		 PMID:18799622 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 1:159,718,679...159,748,449
Ensembl chr 1:159,726,004...159,748,408 		JBrowse link
G Gprasp1 G protein-coupled receptor associated sorting protein 1 involved_in ISO
IEA
ISS		 (PMID:23954414)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:23954414 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:98,764,853...98,772,685
Ensembl chr  X:98,709,841...98,772,851 		JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate IMP RGD PMID:19808888 RGD:4892648 NCBI chr10:105,739,617...105,757,838
Ensembl chr10:105,739,296...105,757,835 		JBrowse link
G Hook1 hook microtubule-tethering protein 1 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr 5:110,824,501...110,887,791
Ensembl chr 5:110,824,501...110,887,787 		JBrowse link
G Hook2 hook microtubule-tethering protein 2 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr19:23,151,869...23,170,139
Ensembl chr19:23,151,870...23,164,181 		JBrowse link
G Hook3 hook microtubule-tethering protein 3 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr16:65,954,293...66,058,812
Ensembl chr16:65,954,350...66,061,338 		JBrowse link
G Kif13a kinesin family member 13A involved_in ISO (PMID:19841138) RGD PMID:19841138 NCBI chr17:17,766,597...17,948,517
Ensembl chr17:17,766,597...17,943,615 		JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:6364606 (MGI:6510385|PMID:33357458)
GO_REF:0000107		 RGD
Ensembl		 PMID:33357458 GO_REF:0000107 MGI:6510385 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Mgrn1 mahogunin ring finger 1 involved_in ISO
IEA
IBA		 (PMID:17229889)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:17229889 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr10:10,638,881...10,688,332
Ensembl chr10:10,638,880...10,688,315 		JBrowse link
G Mtm1 myotubularin 1 involved_in ISO
ISS		 (PMID:14722070)
GO_REF:0000024		 RGD
UniProt		 PMID:14722070 GO_REF:0000024 NCBI chr 6:488,923...506,882
Ensembl chr 6:488,969...506,860 		JBrowse link
G Pcdhga3 protocadherin gamma subfamily A, 3 acts_upstream_of_or_within ISO (MGI:5317350|PMID:21917590) RGD PMID:21917590 MGI:5317350 NCBI chr18:29,499,148...29,667,865
Ensembl chr18:29,493,954...29,667,868 		JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:90,908,304...90,915,862
Ensembl chr 1:90,904,742...90,915,820 		JBrowse link
G Plekhf2 pleckstrin homology and FYVE domain containing 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:24,091,077...24,106,758
Ensembl chr 5:24,090,688...24,106,601 		JBrowse link
G Pxk PX domain containing serine/threonine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:16,759,857...16,828,452
Ensembl chr15:16,759,862...16,828,444 		JBrowse link
G Rab12 RAB12, member RAS oncogene family involved_in ISS
ISO		 GO_REF:0000024
(MGI:5448516|PMID:21718402)		 UniProt
RGD		 PMID:21718402 GO_REF:0000024 MGI:5448516 NCBI chr 9:106,480,301...106,506,895
Ensembl chr 9:106,480,301...106,506,910 		JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO
IBA		 (PMID:18272684)
PMID:21873635		 RGD PMID:18272684 PMID:21873635 RGD:13792537 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889 		JBrowse link
G Rab7b Rab7b, member RAS oncogene family involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581 		JBrowse link
G Rhob ras homolog family member B involved_in ISO
ISS		 (PMID:10508588)
GO_REF:0000024		 RGD
UniProt		 PMID:10508588 GO_REF:0000024 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108 		JBrowse link
G Rilp Rab interacting lysosomal protein involved_in ISO (PMID:18272684) RGD PMID:18272684 NCBI chr10:60,355,276...60,358,434
Ensembl chr10:60,355,278...60,358,781 		JBrowse link
G Scyl2 SCY1 like pseudokinase 2 involved_in ISO (PMID:19643732) RGD PMID:19643732 NCBI chr 7:24,064,404...24,117,338
Ensembl chr 7:24,064,404...24,117,305 		JBrowse link
G Snapin SNAP-associated protein involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
UniProtKB:Q6ZNE5 (PMID:22797916)		 Ensembl
RGD		 PMID:22797916 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 2:175,971,575...175,974,164
Ensembl chr 2:175,971,257...175,974,231 		JBrowse link
G Snx16 sorting nexin 16 involved_in IBA
IEA
ISS
ISO		 PMID:21873635
GO_REF:0000107
GO_REF:0000024
(PMID:12813048)		 Ensembl
UniProt
RGD		 PMID:12813048 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 2:91,335,896...91,357,622
Ensembl chr 2:91,336,092...91,357,619 		JBrowse link
G Snx27 sorting nexin 27 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:182,135,904...182,218,906
Ensembl chr 2:182,135,905...182,218,906 		JBrowse link
G Sort1 sortilin 1 involved_in ISO
IEA		 (PMID:11331584)
GO_REF:0000107		 RGD
Ensembl		 PMID:11331584 GO_REF:0000107 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354 		JBrowse link
G Stx7 syntaxin 7 IDA RGD PMID:15133481 RGD:4892614 NCBI chr 1:21,197,075...21,237,320
Ensembl chr 1:21,197,075...21,237,279 		JBrowse link
G Stx8 syntaxin 8 IDA RGD PMID:15133481 RGD:4892614 NCBI chr10:52,655,643...52,900,048
Ensembl chr10:52,654,990...52,894,993 		JBrowse link
G Tgfbrap1 transforming growth factor, beta receptor associated protein 1 involved_in ISO (PMID:25266290) RGD PMID:25266290 NCBI chr 9:45,320,975...45,371,329
Ensembl chr 9:45,320,930...45,371,311 		JBrowse link
G Trak1 trafficking kinesin protein 1 involved_in ISO
IBA		 (PMID:18675823)
PMID:21873635		 RGD PMID:18675823 PMID:21873635 RGD:13792537 NCBI chr 8:120,984,445...121,139,357
Ensembl chr 8:120,984,431...121,139,367 		JBrowse link
G Trak2 trafficking kinesin protein 2 IDA RGD PMID:17062640 RGD:13208835 NCBI chr 9:60,348,531...60,414,036
Ensembl chr 9:60,350,012...60,413,996 		JBrowse link
G Tsg101 tumor susceptibility 101 involved_in IMP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:19808888 PMID:21873635 RGD:4892648, RGD:13792537 NCBI chr 1:97,412,689...97,442,589
Ensembl chr 1:97,410,848...97,442,554 		JBrowse link
G Uevld UEV and lactate/malate dehyrogenase domains involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:97,454,188...97,486,004
Ensembl chr 1:97,453,946...97,486,000 		JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in IDA
IBA
ISO		 PMID:21873635
(PMID:10888671)
PMID:15133481		 RGD PMID:10888671 PMID:15133481 PMID:21873635 PMID:15133481 RGD:4892614, RGD:13792537, RGD:4892614 NCBI chr12:16,728,486...16,764,261
Ensembl chr12:16,728,524...16,764,097 		JBrowse link
G Vipas39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog involved_in
NOT|involved_in		 ISO
IEA		 (PMID:19109425)
GO_REF:0000107
(PMID:25783203)		 RGD
Ensembl		 PMID:19109425 PMID:25783203 GO_REF:0000107 NCBI chr 6:106,888,284...106,913,139
Ensembl chr 6:106,888,284...106,913,117 		JBrowse link
G Vps11 VPS11 core subunit of CORVET and HOPS complexes involved_in ISO (PMID:25783203) RGD PMID:25783203 NCBI chr 8:44,684,129...44,698,568
Ensembl chr 8:44,684,127...44,698,568 		JBrowse link
G Vps16 VPS16 core subunit of CORVET and HOPS complexes involved_in ISO (PMID:25783203) RGD PMID:25783203 NCBI chr 3:117,622,534...117,644,041
Ensembl chr 3:117,622,542...117,646,441 		JBrowse link
G Vps18 VPS18 core subunit of CORVET and HOPS complexes involved_in ISO
IBA		 (PMID:25783203)
PMID:21873635		 RGD PMID:25783203 PMID:21873635 RGD:13792537 NCBI chr 3:106,279,444...106,290,298
Ensembl chr 3:106,279,425...106,291,964 		JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes involved_in ISO
IEA		 (PMID:25783203)
GO_REF:0000107		 RGD
Ensembl		 PMID:25783203 GO_REF:0000107 NCBI chr12:33,024,596...33,051,399
Ensembl chr12:33,024,650...33,051,393 		JBrowse link
G Vps33b VPS33B, late endosome and lysosome associated NOT|involved_in ISO (PMID:25783203) RGD PMID:25783203 NCBI chr 1:134,223,967...134,247,232
Ensembl chr 1:134,223,949...134,246,970 		JBrowse link
G Vps39 VPS39 subunit of HOPS complex involved_in ISO (PMID:25266290), (PMID:25783203) RGD PMID:25266290 PMID:25783203 NCBI chr 3:107,266,846...107,304,884
Ensembl chr 3:107,267,310...107,304,975 		JBrowse link
G Vps41 VPS41 subunit of HOPS complex involved_in ISO (PMID:25783203) RGD PMID:25783203 NCBI chr17:46,063,132...46,227,533
Ensembl chr17:46,063,124...46,227,791 		JBrowse link
endosome to lysosome transport of low-density lipoprotein particle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl8b ADP-ribosylation factor like GTPase 8B involved_in ISS
ISO		 GO_REF:0000024
(PMID:21802320)		 UniProt
RGD		 PMID:21802320 GO_REF:0000024 NCBI chr 4:141,748,634...141,792,605
Ensembl chr 4:141,748,587...141,792,596 		JBrowse link
G Tpcn2 two pore segment channel 2 involved_in ISO (MGI:5691857|PMID:25144390) RGD PMID:25144390 MGI:5691857 NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236 		JBrowse link
endosome to lysosome transport via multivesicular body sorting pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lyst lysosomal trafficking regulator involved_in ISO (PMID:9606205) RGD PMID:9606205 NCBI chr17:86,241,384...86,443,501
Ensembl chr17:86,241,384...86,443,480 		JBrowse link
G Mvb12a multivesicular body subunit 12A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:18,252,227...18,257,111
Ensembl chr16:18,252,222...18,257,539 		JBrowse link
G Ubxn6 UBX domain protein 6 involved_in ISO (PMID:21822278) RGD PMID:21822278 NCBI chr 9:900,883...906,047
Ensembl chr 9:900,884...906,124 		JBrowse link
G Vcp valosin-containing protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:21822278)		 UniProt
RGD		 PMID:21822278 GO_REF:0000024 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:15024011) RGD PMID:15024011 NCBI chr13:22,907,105...22,932,200
Ensembl chr13:22,907,109...22,932,229 		JBrowse link
multivesicular body-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp3 charged multivesicular body protein 3 involved_in ISO (PMID:16554368) RGD PMID:16554368 NCBI chr 4:103,576,453...103,622,566
Ensembl chr 4:103,576,515...103,623,959 		JBrowse link
neurotransmitter receptor transport, postsynaptic endosome to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3d1 adaptor related protein complex 3 subunit delta 1 involved_in IBA
ISO		 PMID:21873635
(MGI:5819335|PMID:24217640)		 RGD PMID:24217640 PMID:21873635 MGI:5819335, RGD:13792537 NCBI chr 7:8,970,249...9,005,651
Ensembl chr 7:8,970,291...9,005,643 		JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 involved_in IBA
ISO		 PMID:21873635
(MGI:5819335|PMID:24217640)		 RGD PMID:24217640 PMID:21873635 MGI:5819335, RGD:13792537 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227 		JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:177,201,361...177,297,019
Ensembl chr 1:177,201,288...177,297,024 		JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:92,683,778...92,745,842
Ensembl chr10:92,683,761...92,746,126 		JBrowse link
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:92,827,441...92,869,632
Ensembl chr10:92,829,196...92,869,614 		JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:65,800,059...65,831,246
Ensembl chr 1:65,800,355...65,831,006 		JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:65,755,334...65,775,567
Ensembl chr 1:65,755,334...65,779,089 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    cellular process 18233
      vesicle-mediated transport 1576
        endosome to lysosome transport 65
          endosome to lysosome transport of low-density lipoprotein particle 2
          endosome to lysosome transport via multivesicular body sorting pathway + 6
          neurotransmitter receptor transport, postsynaptic endosome to lysosome 7
Path 2
Term Annotations click to browse term
  biological_process 19553
    localization 5546
      establishment of localization 4870
        transport 4545
          intracellular transport 1357
            vacuolar transport 139
              lysosomal transport 114
                endosome to lysosome transport 65
                  endosome to lysosome transport of low-density lipoprotein particle 2
                  endosome to lysosome transport via multivesicular body sorting pathway + 6
                  neurotransmitter receptor transport, postsynaptic endosome to lysosome 7
paths to the root